Clinical trials: Post ERCP Acute Pancreatitis
Post-ERCP Acute Pancreatitis
Low-acid Contrast Media for Preventing Post ERCP Pancreatitis
Title： Low-acid contrast media for preventing post ERCP pancreatitis: a multicenter, retrospective, cohort study (LAMP-R) . Objective: Main objective: This study aims to determine whether low-acid contrast media can reduce the…
- Trial name
- LAMP-R (NCT07391787)
- Testing
- Ioversol, Iopromide, Iohexol
- Where
- 2 sites in China
- Volunteers
- 3,979 people
- Sponsor
- Shandong University
Pancreatitis, Acute, Gastrointestinal Disease
Oral Resveratrol to Prevent Post-ERCP Pancreatitis
Acute pancreatitis is the most common and feared complication of ERCP, occurring after 1% to 30% of procedures. Since 2012, a multicenter RCT was published in NEJM, indomethacin use in high risk patients was considered a…
- Trial name
- NCT02947932
- Testing
- Resveratrol, Indomethacin
- Volunteers
- 2,700 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Post-ERCP Acute Pancreatitis
Randomized Controlled Trial of Rectal Indomethacin Versus Combined Pancreatic Stent Placement and Rectal Indomethacin for Preventing Post-ERCP Pancreatitis
The goal of this clinical trial is to compare rectal indomethacin alone versus combined pancreatic duct stenting and rectal indomethacin in prevention of post ERCP pancreatitis.
- Trial name
- NCT05857514
- Testing
- Rectal Indomethacin, Prophylactic Pancreatic duct stenting
- Where
- 2 sites in India
- Volunteers
- 384 people
- Sponsor
- Moti Lal Nehru Medical College
Post-ERCP Acute Pancreatitis
Rectal Indomethacin and Oral Tacrolimus Versus Combination to Prevent Post-ERCP Pancreatitis
This research is being done to see if using oral tacrolimus before endoscopy, can prevent pancreatitis that may occur after ERCP (a type of gastrointestinal endoscopy).
- Trial name
- INTRO (NCT05252754)
- Testing
- Tacrolimus capsule, Rectal Indomethacin
- Where
- 5 sites in United States, India and 1 more
- Volunteers
- 4,874 people
- Sponsor
- Johns Hopkins University
Choledocholithiasis, Cholecystolithiasis
One-stage and Delayed Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiopancreatography with Endoscopic Sphincterotomy in Cholecystocholedocholithiasis
In this study, it is planned to compare ERCP with ES + delayed LC in children, with one-stage LC + ERCP with ES in adults to confirm that ERCP with ES + delayed LC is more suitable for pediatric patients with…
- Conditions
- Choledocholithiasis, Cholecystolithiasis, Cholangiopancreatography, Endoscopic Retrograde, Laparoscopic Cholecystectomy
- Trial name
- NCT06676241
- Testing
- endoscopic retrograde cholangiopancreatography; laparoscopic cholecystectomy, endoscopic retrograde cholangiopancreatography;laparoscopic cholecystectomy
- Where
- Russia
- Volunteers
- 44 people
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
Post-ERCP Acute Pancreatitis, NSAIDs
Prevention of Post-ERCP Pancreatitis by Indomethacin vs Diclofenac
Post-ERCP pancreatitis (PEP) is the most common complication after ERCP, which was associated with occasional mortality, prolonged hospital days and increased health costs.
- Conditions
- Post-ERCP Acute Pancreatitis, NSAIDs, Indomethacin, Diclofenac
- Trial name
- NCT05947461
- Testing
- 100mg diclofenac, 100mg indomethacin
- Where
- 11 sites in China
- Volunteers
- 1,204 people
- Sponsor
- Air Force Military Medical University, China
Post-ERCP Acute Pancreatitis
Post-ERCP Pancreatitis Prevention by Stent Insertion
The presented study is designed to analyze the efficacy of pancreatic stent insertion in patients undergoing ERCP with accidental cannulation of the pancreatic duct.
- Trial name
- PEPSI (NCT01673763)
- Testing
- Stent insertion into the main pancreatic duct
- Where
- 4 sites in Belgium, Germany and 2 more
- Volunteers
- 169 people
- Sponsor
- Technical University of Munich
Pancreatitis, Acute
Prophylaxis of Post-ERCP Acute Pancreatitis
This study aims to compare indomethacin and the combination of indomethacin and aggressive lactated Ringer infusion in terms of efficacy in preventing post-ERCP acute pancreatitis (PEP).
- Trial name
- PEPPER (NCT05381428)
- Testing
- Indomethacin suppository, Indomethacin suppository and high-flow lactated ringer infusion combination
- Where
- 10 sites in Italy
- Volunteers
- 184 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Post-ERCP Acute Pancreatitis.
Diclofenac vs. Placebo in a Randomized Double Blind Controlled Trial in Post ERCP Pancreatitis
1. The most common complication of endoscopic retrograde cholangio-pancreaticography (ERCP) is pancreatitis. 2. Several studies showed that non-steroidal anti-inflammatory drugs (NSAIDs) can prevent the post ERCP pancreatitis…
- Trial name
- NCT01946984
- Testing
- ERCP, Diclofenac hydroxyethylpyrrolidine, Normal Saline
- Where
- Palestinian Territories
- Volunteers
- 182 people
- Sponsor
- Specialized Arab Hospital
Post-ERCP Acute Pancreatitis
Study of Forceps Cannulation During ERCP
A difficult cannulation has been identified as one of the high risk factors for developing post-ERCP pancreatitis (PEP). The accessibility and morphology of the papilla influence the level of cannulation difficulty.
- Trial name
- SOCCER (NCT05336630)
- Testing
- Forceps
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Post-ERCP Acute Pancreatitis
Lactated Ringers With or Without Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
Post-ERCP pancreatitis is a well-known and sometimes life-threatening complication of ERCP. Both LR and rectal indomethacin have shown benefit in preventing post-ERCP pancreatitis.
- Trial name
- IND+LRPEP (NCT02641561)
- Testing
- Indomethacin, Lactated Ringer's Solution, Normal Saline
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Acute Pancreatitis
The Association Between Post-ERCP Acute Pancreatitis and Various Genetic Mutations
Pancreatitis remains the most common complication of ERCP, with the reported incidence ranging from 2% to 9%. Although 80% of cases are mild, a significant number of patients may develop severe pancreatitis, that means additional…
- Trial name
- NCT02928718
- Testing
- ERCP
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Seoul National University Hospital
Acute Pancreatitis
Study of Peripheral Blood Non-coding RNAs as Diagnosis and Prognosis Biomarker for Acute Pancreatitis
It is important to identify patients with acute pancreatitis who are at risk for developing persistent organ failure early in the course of disease.
- Trial name
- NCRNAP (NCT02602808)
- Where
- 3 sites in China
- Volunteers
- 1,097 people
- Sponsor
- Changhai Hospital
Post-ERCP Acute Pancreatitis
Lactated Ringer's Solution to Prevent Post-ERCP Pancreatitis
This is a randomized, double-blinded, controlled trial. This study is a head to head comparison of normal saline (NS) infusion versus Lactated Ringer's (LR) infusion in patients, with the primary outcome of post-ERCP pancreatitis…
- Trial name
- NCT03215862
- Testing
- Lactated Ringer, Normal Saline 0.9% Infusion Solution Bag
- Volunteers
- 242 people
- Sponsor
- University of South Florida
Acute Biliary Pancreatitis
Prophylactic Sphincterotomy in Acute Biliary Pancreatitis Patients Unfit for Surgery
This is a prospective, multicenter, open-label, randomized controlled trial designed to evaluate the efficacy and safety of prophylactic endoscopic sphincterotomy (ES) in frail patients unfit for cholecystectomy following an…
- Trial name
- PROSECCO (NCT07238296)
- Testing
- Prophylactic endoscopic sphincterotomy
- Volunteers
- 92 people
- Sponsor
- Semmelweis University
Post-ERCP Acute Pancreatitis
Incidence and Risk Factor of Post-ERCP Pancreatitis in Chronic Pancreatitis
The purpose of this study is to compare the incidence of post-ERCP pancreatitis (PEP) in chronic pancreatitis (CP) patients to that in biliary disease patients, to determine whether CP patients in early clinical stage have a…
- Trial name
- NCT02781987
- Testing
- chronic pancreatitis
- Volunteers
- 2,028 people
- Sponsor
- Changhai Hospital
Post ERCP Acute Pancreatitis
Indomethacin Decreases Post-ERCP Pancreatitis
Endoscopic retrograde cholangiopancreatography (ERCP) is now a widely accepted therapy for treating benign and malignant diseases of the pancreatobiliary tree.
- Trial name
- Indomethacin (NCT02110810)
- Testing
- Indomethacin, 2.6-g suppository of glycerin
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Instituto Mexicano del Seguro Social
Acute Pancreatitis
Timing of Indomethacin Administration for the Prevention of Post-ERCP Pancreatitis (PEP)
To determine if the timing of administration of indomethacin affects the primary outcome of post-ERCP pancreatitis (PEP). Patients undergoing ERCP will be randomly assigned to receive pre or post-procedure rectal indomethacin to…
- Trial name
- NCT02111707
- Testing
- Rectal indomethacin 100mg one time before or after ERCP
- Where
- Canada
- Volunteers
- 534 people
- Sponsor
- University of Alberta
Post-ERCP Acute Pancreatitis
IV Ibuprofen for the Prevention of Post-ERCP Pancreatitis
Endoscopic retrograde cholangiopancreatography (ERCP) is an advanced endoscopic technique utilized to diagnose and treat pathologic conditions involving the ducts draining the liver and pancreas.
- Trial name
- NCT02241512
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Texas Southwestern Medical Center
Post-ERCP Acute Pancreatitis
Somatostatin, Octreotide, Pentoxyfilline in the Prevention of Post-ERCP Pancreatitis and Molecular Markers
Octreotide, somatostatin and pentoxyfilline commercially available drugs that are used in various clinical situations. They are safe and known for years.
- Trial name
- NCT00222092
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Ioannina