Clinical trials: Post Extraction Complication
Surgery, Pain, Postoperative
Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial
This trial is being completed to compare two commonly used options to treat pain after surgery. Participants that undergo gallbladder removal, hernia repair, and breast lump removal will be eligible to enroll.
- Trial name
- CARES (NCT05722002)
- Testing
- NSAID, Opioid, Acetaminophen
- Where
- 8 sites in United States, Canada
- Volunteers
- 900 people
- Sponsor
- University of Michigan
Post Operative Pain, Impacted Third Molar Tooth
Jaw Muscle Pain Post Wisdom Molar Surgery
The proposed design is a triple-blind, placebo-controlled randomized prospective phase II trial to assess the feasibility of employing the Temporo-masseteric Nerve Block (TMNB) injection to decrease jaw muscle pain, overall pain…
- Conditions
- Post Operative Pain, Impacted Third Molar Tooth, Muscle Pain
- Trial name
- NCT07094542
- Testing
- Temporo-masseteric Nerve Block Injection, Oral Pain Medications only
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Acute Pain
Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction
This study aims to evaluate the analgesic efficacy of single and multiple doses of a new fixed dose combination of nefopam hydrochloride 30 mg and paracetamol 500mg taken orally in comparison to each single component.
- Trial name
- NCT04622735
- Testing
- nefopam hydrochloride 30mg / paracetamol 500mg X2, Paracetamol 500 Mg Oral Tablet X2, Nefopam HCl 30 MG Oral Tablet X2
- Where
- 19 sites in Belgium, France and 3 more
- Volunteers
- 321 people
- Sponsor
- Unither Pharmaceuticals, France
Acute Kidney Injury, Cardiac Surgery
Fluid-removal Guided by VeXUS Score With Usual Care in Patients With Acute Kidney Injury After Cardiac Surgery
Acute kidney injury affects more than 30% of patients after cardiac surgery, and is associated with an excess in mortality. There is a clinical continuum between acute kidney injury (transient if <48h, persistent if >48h), the…
- Conditions
- Acute Kidney Injury, Cardiac Surgery, Venous Congestion, Hemodynamic Stability
- Trial name
- VeXUS (NCT06251713)
- Testing
- VeXUS score guided fluid management strategy, Usual care
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Bacteriuria Asymptomatic, Urinary Tract Infections
Bacteriuria and Indwelling Urinary Catheter.
Investigation of 1. The incidence of symptomatic bacteriuria during four weeks after removal of an IUC in inpatients at a rehabilitation clinic for patients ≥ 65 years compared with the incidence of symptomatic bacteriuria among…
- Trial name
- NCT05039203
- Testing
- Indwelling urinary catheter
- Where
- 2 sites in Sweden
- Volunteers
- 196 people
- Sponsor
- Region Stockholm
Facial Pain, Pain, Postoperative
Effectiveness of Alveogyl and Cutanplast Dressing on Postoperative Pain Following Tooth Extraction: A Clinical Trial
This study aims to assess the post-dental extraction pain following the application of two different dressing materials. Alvogyl® and Absorbable gelatin sponges
- Conditions
- Facial Pain, Pain, Postoperative, Pain, Orofacial
- Trial name
- NCT04779476
- Testing
- Socket Dressing
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Riyadh Elm University
Pain, Post Operative, Quality of Life
Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft
The goal of this randomized clinical trial is to compare patient-reported pain and oral health-related quality of life during the first postoperative week following extraction and bone graft surgery in patients who received…
- Trial name
- NCT05919745
- Testing
- Ibuprofen 600 mg, Acetaminophen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marquette University
Anesthesia Recovery
Airway Complications After LMA in Children
Background: The removal of Laryngeal Mask Airway (LMA) in children may be associated with respiratory adverse events. The incidence of these adverse events may be influenced by the type of anesthesia maintenance.
- Trial name
- NCT03553082
- Testing
- Sevoflurane, Propofol
- Where
- Lebanon
- Volunteers
- 135 people
- Sponsor
- American University of Beirut Medical Center
Acute Pain, Postoperative
This is a Study Evaluating the Efficacy and Safety of LTG-001 for Acute Pain After Surgical Removal of Impacted Third Molars
The goal of this clinical trial is to learn if LTG-001 works to treat pain after third molar removal surgery in adults. It will also learn about the safety of LTG-001.
- Trial name
- NCT06774625
- Testing
- LTG-001 High Dose, LTG-001 Mid Dose, LTG-001 Low Dose
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Latigo Biotherapeutics
Impacted Mandibular Third Molar, Postoperative Pain
Effect of Platelet-Rich Fibrin on Postoperative Pain, Trismus, and Edema After Mandibular Third Molar Surgery
Impacted mandibular third molars are among the most commonly encountered conditions in oral and maxillofacial surgery. Surgical removal of these teeth is frequently associated with postoperative complications such as pain, facial…
- Conditions
- Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Edema Face
- Trial name
- PRF-M3M (NCT07672951)
- Testing
- Platelet-rich fibrin (PRF), Sterile Absorbable Gelatin Sponge
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- PAEC General Hospital, Islamabad
Wound Healing, Alveolitis of Jaw
Effect of Curcumin Topical Spray on Wound Healing After Tooth Extraction
This randomized, single-blind, controlled clinical trial aims to evaluate the effects of a topical curcumin spray on post-extraction wound healing and postoperative symptoms in adults undergoing first molar extraction.
- Conditions
- Wound Healing, Alveolitis of Jaw, Tooth Extraction, Curcumin
- Trial name
- NCT07874789
- Testing
- Curcumin Topical Spray, Chlorhexidine Topical Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Surgical Complication, Colonic Disease
Immediate Versus Early (24-hours) Urinary Catheter Removal After Elective Minimally Invasive Colonic Resection
The primary aim of this study is to compare the rate of acute urinary retention (AUR) after immediate compared to early (24-hours) removal of urinary catheter (UC) in patients undergoing minimally invasive colorectal resection.
- Conditions
- Surgical Complication, Colonic Disease, Postoperative Complications, Urinary Retention Postoperative
- Trial name
- NCT05249192
- Testing
- Immediate urinary catheter removal, Early urinary catheter removal
- Where
- Italy
- Volunteers
- 216 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Postoperative Complications, Cataract
Safety and Efficacy Study of Topical Bromfenac Versus Placebo to Treat Ocular Inflammation After Cataract Surgery
The primary objective of this study was to investigate the efficacy of bromfenac sodium ophthalmic solution 0.09% for treatment of post-operative ocular inflammation in subjects who undergo cataract extraction and intraocular…
- Trial name
- NCT00198445
- Testing
- Bromfenac
- Where
- 39 sites in United States
- Volunteers
- 527 people
- Sponsor
- Bausch & Lomb Incorporated
Post-Operative Pain, Third Molar Extraction
Efficacy and Safety of Intranasal Morphine for Pain After Third Molar Extraction
This study involves approximately 200 patients designed to evaluate the efficacy and safety of intranasal (IN) morphine 7.5 mg and 15 mg, intravenous morphine (IV) 7.5 mg, immediate release oral (PO) morphine 60 mg or placebo in…
- Trial name
- NCT00390312
- Testing
- Intranasal Morphine 15 mg, Immediate Release Oral Morphine 60 mg, Intravenous morphine
- Volunteers
- 225 people
- Sponsor
- Javelin Pharmaceuticals
Post Operative Pain
Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars
1. To compare the postoperative pain between the patients who receive the systemic enzyme therapy and patients in the control group in the third and seventh day. 2.
- Trial name
- NCT05681312
- Testing
- systemic proteolytic enzyme (Tibrolin), Amoxicillin 500mg+metronidazole 500mg+ doliprane 100mg
- Where
- Iraq
- Volunteers
- 55 people
- Sponsor
- University of Baghdad
Pain, Postoperative
Potential Benefit of the Combination of Metamizole and Ibuprofen After Third Lower Molar Extraction
Postoperative pain is common and particularly outpatients may experience unsatisfactory pain relief. This randomized, double-blind, crossover study of postoperative pain in outpatients undergoing split-mouth, third lower molar…
- Trial name
- NovIbu (NCT02686021)
- Testing
- Metamizole and Ibuprofen
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University Hospital, Basel, Switzerland
Tooth Extraction, Postoperative Hemorrhage
Post-extraction Bleeding in Older Adults on Uninterrupted Antiplatelet Therapy
This prospective, assessor-blinded, controlled observational study compares bleeding after simple tooth extraction between adults aged 40 years or older who continue their antiplatelet therapy (aspirin, clopidogrel or dual…
- Conditions
- Tooth Extraction, Postoperative Hemorrhage, Platelet Aggregation Inhibitors
- Trial name
- NCT07913035
- Testing
- Antiplatelet therapy (uninterrupted), Simple tooth extraction with stepwise local haemostatic protocol
- Where
- Vietnam
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Kidney Transplant; Complications, Kidney Transplant Infection
Early vs Late Urinary Catheter Removal After Renal Transplantation
The purpose of this study is to compare frequency of UTI, urine leak and need for reoperation in patients after renal transplant with early or delayed Foley catheter removal.
- Conditions
- Kidney Transplant; Complications, Kidney Transplant Infection, Urinary Fistula, Urinary Tract Infections
- Trial name
- ELUCATR (NCT04815954)
- Testing
- Urinary catheter removal
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Warsaw
To Control Pain After Third Molar Surgery
Efficacy of Preoperative Administration of Paracetamol-codeine on Pain Following Impacted Mandibular Third Molar Surgery
Objectives: The aim of this study was to determine the effectiveness of preoperative administration of single-dose of paracetamol-codeine, in the relieving of acute post-operative pain after the surgical removal of an impacted…
- Trial name
- NCT03049878
- Testing
- Paracetamol Codeine
- Volunteers
- 32 people
- Sponsor
- University of Roma La Sapienza
Urinary Tract Infections
Early or Late Foley Removal After Thoracotomy
Is the early removal of Foley catheter safe in patients undergoing general thoracic surgery with an epidural catheter in place?
- Trial name
- NCT01611519
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic