Clinical trials: Post Herpetic Neuralgia
Zoster Without Complications
Regional Anesthesia to Relief Zoster Pain
Pain in Herpes is a serious issue for patients. at the acute phase it is a moderate to severe pain . 30% patients will develop a post herpetic neuralgia this percentage up to 70 % after 60 years old.
- Trial name
- NCT04133142
- Testing
- peripheral nerve block, inter fascial nerve block
- Where
- Vietnam
- Sponsor
- Vinmec Healthcare System
PHN - Post-Herpetic Neuritis
The Drug-drug Interaction of HSK16149 Capsule With Probenecid Tablets or Cimetidine Tablets in Healthy Subjects
This study is a single-center, open-label, crossover study, conducted in healthy Chinese populations, and plans to enroll 48 healthy adult subjects (male and female).
- Trial name
- NCT05881811
- Testing
- HSK16149，probenecid, cimetidine
- Where
- China
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Postherpetic Neuralgia, Healthy Age/Gender Matched Volunteers
Evaluation of Five Selected Markers in Skin Biopsies of Patients With Postherpetic Neuralgia and Healthy Controls
Postherpetic Neuralgia is a painful nerve condition that can occur when nerve fibers are damaged following an outbreak of shingles.
- Trial name
- STTR (NCT01379716)
- Testing
- skin biopsy
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Post Herpetic Neuralgia
A Study With Lido-Patch and Placebo Plaster in Patients Suffering From Postherpetic Neuralgia (PHN)
This study investigated the efficacy of the Lido-Patch (lidocaine 5% medicated plaster) in treatment of pain caused by PHN which is a neuropathic pain syndrome (nerve-related pain conditions) following an acute attack of herpes…
- Trial name
- NCT03745404
- Testing
- Lidocaine 5% medicated Plaster
- Volunteers
- 265 people
- Sponsor
- Grünenthal GmbH
Neuralgia, Pain
Pilot Study of High-Dose Capsaicin Patches to Treat Postherpetic Neuralgia Pain
The purpose of this study is to gain initial information on the tolerability of high-dose capsaicin patches in patients with Painful Postherpetic Neuralgia.
- Conditions
- Neuralgia, Pain, Peripheral Nervous System Diseases, Herpes Zoster
- Trial name
- NCT00034710
- Testing
- Capsaicin Patch
- Where
- 8 sites in United States
- Volunteers
- 42 people
- Sponsor
- NeurogesX
Herpes Zoster
A Study Exploring Efficacy of Peginterferon in Patients With Herpes Zoster
To evaluate the efficacy, optimal dose and efficacy trend of multiple subcutaneous injections of peginterferon α1b in patients with herpes zoster, and provide support for phase III clinical trials.
- Trial name
- NCT05492591
- Testing
- Peginterferon α1b, Peginterferon α1b with valacyclovir, Valacyclovir
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Institute Of Biological Products
Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis
Prospective Observation of the Fluoroscopy-guided Cervical Epidural Approach Using the Contralateral Oblique View
The aim of the present study is to investigate the safety and clinical utility of contralateral oblique view for fluoroscopic guided cervical epidural access.
- Conditions
- Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis, Cervical Radicular Pain, Herpes Zoster
- Trial name
- NCT04774458
- Testing
- Fluoroscopic-guided cervical epidural access
- Where
- South Korea
- Volunteers
- 439 people
- Sponsor
- Asan Medical Center
Postherpetic Neuralgia, Pain
Study of NGX-1998 for the Treatment of Postherpetic Neuralgia
The purpose of this study is to assess the efficacy, safety and tolerability of NGX-1998 applied for 5 minutes for the treatment of postherpetic neuralgia (PHN).
- Trial name
- NCT01228838
- Testing
- NGX-1998
- Where
- 35 sites in United States
- Volunteers
- 183 people
- Sponsor
- NeurogesX
Herpes Zoster, Neuralgia
NGX-4010 for the Treatment of Postherpetic Neuralgia
The purpose of the study is determine if an investigational drug, NGX-4010 (high-concentration capsaicin dermal patches) is effective in treating pain associated with post-herpetic neuralgia (PHN).
- Conditions
- Herpes Zoster, Neuralgia, Pain, Peripheral Nervous System Diseases
- Trial name
- NCT00061776
- Testing
- Capsaicin Dermal Patch
- Where
- 28 sites in United States
- Volunteers
- 300 people
- Sponsor
- NeurogesX
Neuralgia, Postherpetic
Safety and Efficacy of Gabapentin in Postherpetic Neuralgia
Gabapentin and pregabalin are treatments for some types of neuropathic pain, including postherpetic neuralgia (PHN). However, these treatments usually need to be taken 3 times a day for effective pain control.
- Trial name
- NCT00335933
- Testing
- Gabapentin extended-release tablets
- Where
- United States
- Volunteers
- 378 people
- Sponsor
- Depomed
Postherpetic Neuralgia
Evaluate the Efficacy and Safety of DWP05195 in Subjects With Post-Herpetic Neuralgia
The purpose of this study is to evaluate efficacy, safety of administered DWP05195 in Postherpetic Neuralgia.
- Trial name
- NCT01557010
- Testing
- DWP05195, Control
- Volunteers
- 140 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Shear Wave Elastography
Muscle Elasticity Assessment of Postherpetic Neuralgia Using Elasticity Ultrasound
Herpes zoster (HZ), also known as shingles, is caused by the varicella-zoster virus (VZV). Approximately 1/4 of the global population is affected by HZ, with statistics showing that about 90% of shingles patients experience acute…
- Trial name
- NCT05912738
- Testing
- Interventional therapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Postherpetic Neuralgia ( PHN )
Intradermal Exosomes, Platelet-Rich Plasma, and Steroids for Post-Herpetic Neuralgia
This randomized controlled clinical trial will evaluate and compare the efficacy and safety of intradermal injection of exosomes, platelet-rich plasma, and corticosteroid in patients with post-herpetic neuralgia.
- Trial name
- NCT07565844
- Testing
- Exosomes, PRP, Corticosteroids
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Zagazig University
Healthy Male and Female Subjects
Pharmacokinetics of Y-4 Tablets With Pregabalin Capsules and Riluzole Tablets in U.S. Healthy Participants
The primary goal of this clinical trial is to compare pharmacokinetic characteristics of Y-4 tablets with pregabalin capsules and riluzole tablets in the US healthy adult participants after single oral administration under fasted…
- Trial name
- NCT07618715
- Testing
- Y-4 tablet, Pregabalin capsule, Riluzole tablet
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Neurodawn Pharmaceutical Co., Ltd.
Neuralgia, Postherpetic
A Study Assessing Efficacy of Brivaracetam in Subjects With Persistent Pain After Shingles (Post-herpetic Neuralgia)
Study will assess efficacy, safety and tolerability of brivaracetam in post-herpetic neuralgia (PHN). Duration of 7 weeks divided into 3 periods with no up-titration, nor down-titration.
- Trial name
- NCT00160667
- Testing
- Brivaracetam
- Where
- 50 sites in Belgium, Bulgaria and 8 more
- Volunteers
- 152 people
- Sponsor
- UCB Pharma
Herpes Zoster, Postherpetic Neuralgia
Acupuncture in Herpes Zoster Neuralgia (ACUZoster)
Symptoms that herald herpes zoster include pruritus, dysesthesia and pain along the distribution of the involved dermatome. The most distressing symptom is typically pain and the most feared complication is postherpetic neuralgia…
- Conditions
- Herpes Zoster, Postherpetic Neuralgia, Pain
- Trial name
- ACUZoster (NCT00885586)
- Testing
- gabapentine, Acupuncture
- Where
- Germany
- Volunteers
- 68 people
- Sponsor
- Dominik Irnich
Postherpetic Neuralgia, Neuralgia
An Effectiveness and Safety Study With RWJ-333369 (Carisbamate) for the Study of Postherpetic Neuralgia (PHN).
The purpose of this study is to evaluate the safety, effectiveness, and tolerability of 200 mg of RWJ-333369 given twice daily compared with placebo in the treatment of postherpetic neuralgia.
- Conditions
- Postherpetic Neuralgia, Neuralgia, Herpes Zoster
- Trial name
- NCT00492323
- Testing
- carisbamate
- Volunteers
- 91 people
- Sponsor
- SK Life Science, Inc.
Peripheral Neuropathic Pain
A Phase 1b Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SR419
This study is to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SR419 in Patients with Peripheral Neuropathic Pain
- Trial name
- NCT04494815
- Testing
- SR419, active control
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- Shanghai SIMR Biotechnology Co., Ltd.
Deep Learning
Automated Detection and Diagnosis of Pathological DRGs in PHN Patients Using Deep Learning and Magnetic Resonance
Here, this study aimed to develop an automated system for detecting and diagnosing lesion DRGs in PHN patients based on deep learning.
- Trial name
- NCT06274502
- Testing
- YOLOv8
- Where
- 2 sites in China
- Volunteers
- 41 people
- Sponsor
- Huazhong University of Science and Technology
Post-herpetic Neuralgia
Dose Response Study of EMA401 in Patients With Post-herpetic Neuralgia (PHN)
This study was designed to characterize dose response, and evaluate safety and efficacy of three different doses of EMA401 compared to placebo in patients with post-herpetic neuralgia (PHN).
- Trial name
- EMPHENE (NCT03094195)
- Testing
- EMA401
- Where
- 58 sites in Australia, Austria and 17 more
- Volunteers
- 130 people
- Sponsor
- Novartis Pharmaceuticals