Clinical trials: Post Herpetic Neuralgia
Neuralgia, Postherpetic
A 13-Week, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Postherpetic Neuralgia
The purpose of this study is to evaluate efficacy and safety of pregabalin in the treatment of postherpetic neuralgia in a dose-ranging manner.
- Trial name
- NCT00394901
- Testing
- Pregabalin
- Where
- 39 sites in Japan
- Volunteers
- 372 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Postherpetic Neuralgia ( PHN )
A Clinical Trial to Evaluate the Efficacy and Safety of HL-1186 Tablet in the Treatment of Postherpetic Neuralgia
This is a multicenter, randomized, double-blind, double-dummy, placebo- and active-controlled, parallel-group trial to evaluate the safety, efficacy and pharmacokinetic (PK) profile of HL-1186 Tablet in patients with postherpetic…
- Trial name
- NCT07758920
- Testing
- HL-1186, Pregabalin capsule
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Yidian Pharmaceutical Technology Development Co., Ltd.
Peripheral Nervous System Diseases, Pain
Study of NGX-4010 for the Treatment of Postherpetic Neuralgia
The purpose of the study is to assess the efficacy and safety of NGX-4010 applied for 60 minutes for the treatment of postherpetic neuralgia (PHN).
- Conditions
- Peripheral Nervous System Diseases, Pain, Neuralgia, Herpes Zoster
- Trial name
- NCT00115310
- Testing
- NGX-4010
- Volunteers
- 400 people
- Sponsor
- NeurogesX
Treatment of PHN
3VM1001 Cream for the Treatment of Pain Associated With Post Herpetic Neuralgia (PHN)
Post-herpetic neuralgia (PHN) is pain following acute herpes zoster; defined as pain lasting longer than 3 months. Current first line management consists of tricyclic anti-depressants and anti-convulsants such as gabapentin and…
- Trial name
- PHN (NCT03421613)
- Testing
- 3VM1001
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- CDA Research Group, Inc.
Herpes Zoster, Pain
The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster
Postherpetic neuralgia (PHN) is the most common complication of herpes zoster (HZ) and represents a major clinical challenge due to its chronicity and impact on quality of life.
- Conditions
- Herpes Zoster, Pain, Postherpetic Neuralgia
- Trial name
- NCT07361796
- Testing
- Venlafaxine combined conventional therapy, Conventional therapy
- Where
- China
- Volunteers
- 832 people
- Sponsor
- Beijing Tiantan Hospital
Postherpetic Neuralgia ( PHN )
Electroacupuncture for PHN: Efficacy and Biomarker Evaluation in a Multicenter, Randomized, Sham-Controlled Trial Protocol
The investigators are conducting a clinical study with the following objectives: to evaluate the clinical efficacy of electroacupuncture combined with pregabalin in treating Postherpetic Neuralgia(PHN); to investigate the…
- Trial name
- NCT06990854
- Testing
- Electroacupuncture (Hans-100A, Nanjing Jisheng Medical Technology, China), Pharmacotherapy：① Pregabalin ( Lyrica™ ，Pfizer Inc. America) ② Methylcobalamin ( Mecobalamin tablets， Weicai (China) Pharmaceutical Co., Ltd， China）
- Where
- China
- Volunteers
- 207 people
- Sponsor
- Dexiong Han
Postherpetic Neuralgia
Efficacy and Safety of Eslicarbazepine Acetate as Therapy for Patients With Post-Herpetic Neuralgia
The primary objective of the study is to assess the efficacy of eslicarbazepine acetate (ESL) as therapy for patients with post-herpetic neuralgia.
- Trial name
- NCT00981227
- Testing
- Eslicarbazepine acetate
- Volunteers
- 567 people
- Sponsor
- Bial - Portela C S.A.
Postpartum Depression
Online PHN CBT for PPD
The primary objective of this study is to determine if online group CBT for PPD delivered by public health nurses is superior to postnatal care as usual in: a) acutely treating PPD, b) reducing relapse and recurrence, c)…
- Trial name
- NCT04928742
- Testing
- Group Cognitive Behavioural Therapy (CBT)
- Where
- Canada
- Volunteers
- 159 people
- Sponsor
- McMaster University
Postherpetic Neuralgia
Efficacy and Safety Study of Z160 in Subjects With Postherpetic Neuralgia
This study will compare Z160 and placebo in patients with Postherpetic Neuralgia for safety and efficacy for a period of 6 weeks.
- Trial name
- PHN (NCT01757873)
- Testing
- Z160
- Where
- 53 sites in United States
- Volunteers
- 144 people
- Sponsor
- Zalicus
Depression Disorders, Herpetic Neuralgia
Ketamine for Postherpetic Neuralgia With Depression
This clinical trial examines the antidepressant efficacy and safety of a single low-dose intravenous esketamine combined with oral duloxetine in patients with postherpetic neuralgia and depression (duration more than 1 month).
- Trial name
- NCT06968624
- Testing
- Intravenous Ketamine Infusions, Intravenous normal saline, Oral Duloxetine 60mg
- Volunteers
- 50 people
- Sponsor
- Huazhong University of Science and Technology
Postherpetic; Neuralgia, Trigeminal (Etiology)
Esketamine Combined With PRF for Trigeminal Postherpetic Neuralgia
This trial's primary objective is to compare the analgesic efficacy of esketamine in combination with pulsed radiofrequency (PRF) against that of PRF monotherapy in patients with trigeminal postherpetic neuralgia (TPHN).
- Trial name
- NCT06914180
- Testing
- esketamine group, control group
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Beijing Tiantan Hospital
Trigeminal Neuralgia, Idiopathic, Postherpetic; Neuralgia, Trigeminal (Etiology)
Ganglionic Local Opioid Analgesia at the Ganglion Cervicale Superius
The blockade of the superior cervical ganglion (GCS) of the sympathetic trunk is a very special form of therapy. The transoral blocking technique, also known as GLOA (ganglionic local opioid analgesia), is very suitable for…
- Conditions
- Trigeminal Neuralgia, Idiopathic, Postherpetic; Neuralgia, Trigeminal (Etiology), Glossopharyngeal Neuralgia, Atypical Facial Pain
- Trial name
- GLOA-MRT (NCT05257655)
- Testing
- MRI after ganglionic local opioid analgesia (GLOA)
- Where
- Austria
- Volunteers
- 3 people
- Sponsor
- Klinikum Klagenfurt am Wörthersee
Neuropathic Pain
Efficacy and Safety of Topical Versus Systemic Treatment in Postherpetic Neuralgia and Diabetic Polyneuropathic Pain
The purpose of this study is to evaluate lidocaine as topical treatment for peripheral neuropathic pain (as stand-alone treatment and in combination with systemic treatment)
- Trial name
- NCT00414349
- Testing
- Topical analgesic, oral intake
- Where
- United Kingdom
- Volunteers
- 431 people
- Sponsor
- Grünenthal GmbH
Pain, Neuropathy;Peripheral
Morphological and Metabolic Changes of Dorsal Root Ganglion and Sympathetic Ganglion in Patients With Postherpetic Neuralgia on MRI
Object: Postherpetic neuralgia (PHN) is pain that persists for 1-3 months after herpes zoster onset. It is the most common complication of herpes zoster and occurs in 15-40% of patients with herpes zoster.
- Trial name
- NCT04880408
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huazhong University of Science and Technology
Pain, Diabetic Neuropathies
A Phase 2 Study of Tapentadol Extended-Release (JNS024ER) ) in Japanese Participants With Chronic Pain Due to Diabetic Neuropathic Pain or Postherpetic Neuralgia
The purpose of this study is to investigate the efficacy and safety of tapentadol extended-release (ER) tablets in Japanese participants with moderate to severe chronic (lasting a long time) pain due to painful diabetic…
- Conditions
- Pain, Diabetic Neuropathies, Neuralgia, Postherpetic Neuralgia
- Trial name
- NCT01124617
- Testing
- Tapentadol
- Where
- 31 sites in Japan
- Volunteers
- 91 people
- Sponsor
- Janssen Pharmaceutical K.K.
Post Herpetic Neuralgia
A Study With Lido-Patch and Placebo Plaster in Patients Suffering From Postherpetic Neuralgia (PHN)
This study investigated the efficacy of the Lido-Patch (lidocaine 5% medicated plaster) in treatment of pain caused by PHN which is a neuropathic pain syndrome (nerve-related pain conditions) following an acute attack of herpes…
- Trial name
- NCT03745404
- Testing
- Lidocaine 5% medicated Plaster
- Volunteers
- 265 people
- Sponsor
- Grünenthal GmbH
Pain
[S,S]-Reboxetine Dose-Range Finding Trial
The purpose of this study is to determine the effectiveness of different doses of [S,S]-Reboxetine in the treatment of chronic pain following a shingles infection
- Trial name
- NCT00288652
- Testing
- [S,S]-Reboxetine
- Where
- 79 sites in United States
- Volunteers
- 280 people
- Sponsor
- Pfizer
Pain, Neuropathic Pain
Study to Evaluate Efficacy, Safety, Tolerability and Pharmacokinetics of AZD1386 in Patients With Peripheral Neuropathic Pain
The primary aim of this study is to investigate if AZD1386 is efficacious as an analgesic in patients with peripheral neuropathic pain.
- Trial name
- AVANT (NCT00976534)
- Testing
- AZD1386
- Where
- 12 sites in Canada, Denmark and 2 more
- Volunteers
- 90 people
- Sponsor
- AstraZeneca
Post-Herpetic Neuralgia (PHN)
Crossover Post-herpetic Neuralgia (PHN)
The purpose of the study is to evaluate the efficacy of study drug (BMS-954561) as compared to placebo in the treatment of patients with post-herpetic neuralgia (PHN).
- Trial name
- NCT01305538
- Testing
- BMS-954561
- Where
- 23 sites in United States, France
- Volunteers
- 100 people
- Sponsor
- Bristol-Myers Squibb
Neuralgia, Shingles
Dose-Finding Study of REN-1654 in Patients With Post-Herpetic Neuralgia
The purpose of this study is to gain initial safety and efficacy data on the experimental agent REN-1654 in patients with painful post-herpetic neuralgia (PHN).
- Conditions
- Neuralgia, Shingles, Peripheral Nervous System Disease
- Trial name
- NCT00099528
- Testing
- REN-1654
- Where
- 16 sites in United States
- Volunteers
- 90 people
- Sponsor
- Renovis