Clinical trials: Post ICU Discharge
Critical Illness, Delirium in the Intensive Care Unit
Pilot Feasibility Study of a Pragmatic Mixed-Methods Randomized Controlled Trial on a Follow-Up Bundle of Care for ICU Survivors and Caregivers
~80% of ICU survivors experience profound long-term cognitive, physical, and psychiatric impairments known as post-intensive care syndrome (PICS).
- Trial name
- IMPACT-ICU (NCT06681649)
- Testing
- Intervention
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Queen's University
Pediatric ALL, Critical Illness
Singapore's Health Outcomes After Critical Illness in Kids
What is the problem? Every year about 2.5 million children are affected by critical illness and require admission to the pediatric intensive care unit (PICU).
- Conditions
- Pediatric ALL, Critical Illness, Post Intensive Care Unit Syndrome
- Trial name
- SHACK (NCT04637113)
- Testing
- This is a non-interventional study
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Stress Ulcer Prophylaxis
Economic Outcomes of Enteral and Parenteral Proton Pump Inhibitor (PPI) Use in the Intensive Care Unit (ICU)
This study will be a retrospective electronic medical chart review of all patients admitted to adult intensive care medicine units (ICU) at The Nebraska Medical Center over a three-year period from January 2006 through December…
- Trial name
- NCT00919152
- Where
- United States
- Volunteers
- 534 people
- Sponsor
- University of Nebraska
Septic Shock
Association Between Muscle L3 CT Scan Muscle Derived Parameters of Muscle Function Upon Intensive Care Unit Admission and 3 Months Mortality After ICU Discharge for Patients Admitted for Septic Shock. The SIMS Study
Muscle dysfunction in intensive care units is associated with significant morbidity and mortality. During septic shock, there is an increased catabolism and systemic inflammation resulting in quantitative and qualitative muscle…
- Trial name
- SIMS (NCT07483710)
- Testing
- Evaluation of muscle dysfunction in intensive care units for septic schock patients
- Where
- 4 sites in France
- Volunteers
- 196 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anxiety, Depression
Nursing Intervention in the Patient Being Discharged From the Intensive Care Unit
Background: Psychiatric disorders, such as anxiety, depression or post-traumatic stress disorder (PTSD), are common among critical disease survivors.
- Trial name
- NCT04527627
- Testing
- Nursing Empowerment Intervention
- Where
- 3 sites in Spain
- Volunteers
- 178 people
- Sponsor
- Hospital Clinic of Barcelona
Covid19
Respiratory Muscle Function, Dyspnea, Exercise Capacity and Quality of Life in Severe COVID19 Patients
Further knowledge regarding sequelae in severe COVID-19 patients who have required ICU admission for invasive mechanical ventilation is still needed.
- Trial name
- NCT04853940
- Testing
- Data collection and clinical testing of subjects
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Health-related Quality of Life
Health-related Quality of Life and Functional Impairments After Intensive Care Unit Discharge
Diagnostic and therapeutic progress of the last twenty years has been accompanied by an evolution in the morbidity and mortality of intensive care unit (ICU) patients.
- Trial name
- CritiQoL2 (NCT05111522)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Versailles Hospital
Heart Failure and Chronic Kidney Disease Post-ICU
Dapagliflozin for Cardio-renal Protection After ICU Discharge
Several millions of patients are admitted to ICUs in Europe or USA each year. We and others, have shown that patients discharged from intensive care units (ICU) have a high incidence of cardiovascular and/or renal events and high…
- Trial name
- DAPA-ICU (NCT07025629)
- Testing
- Dapagliflozin 10 MG Oral Tablet [Farxiga]
- Where
- 2 sites in France
- Volunteers
- 600 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critically Ill Patients
Effects of Compound Ejiao Syrup on Exercise Tolerance and Quality of Life in Critically Ill Patients After ICU Discharge: A Double-Blind, Multicenter,Randomized Controlled Clinical Study
This study, titled "Effect of Compound Ejiao Jiang on Exercise Tolerance and Quality of Life of Critically Ill Patients after Discharge from ICU: A Double-Blind, Multicenter, Randomized Controlled Clinical Study (LIFT Study),"…
- Trial name
- NCT07157748
- Testing
- Fufang E'jiao Jiang
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Third Military Medical University
Critical Illness
REhabilitation After Critical Illness Assisted Discharge Pack (RECAP)
The complexity of critical illness can result in both physical and psychological consequences for survivors, which can extend past the intensive unit care stay and after hospital discharge.
- Trial name
- RECAP (NCT02415634)
- Testing
- RECAP, Control
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- Maire Gilmartin
Posttraumatic Stress Disorder, Parents
Posttraumatic Stress Disorder in Parents and Children After Discharge From the Pediatric Intensive Care Unit
Background: If disorders that occur immediately after a trauma are not treated, they may become chronic and turn into severe health problems.
- Conditions
- Posttraumatic Stress Disorder, Parents, Children, Only
- Trial name
- PTSD (NCT05186844)
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Intensive Care (ICU) Myopathy
Biomechanical Properties in Intensive Care Unit (ICU) Survivors 12-month After Discharge
Intensive care unit (ICU) admission is associated with muscle weakness and ICU survivors report persevering limitation of physical capacity for years after discharge.
- Trial name
- NCT01364714
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Kidney Injury
Impact of a Treatment With Angiotensin Receptor Blocker on Outcome After Acute Kidney Injury in Patients Discharged From the ICU.
The patients discharged from intensive care units (ICU) have a high incidence of cardiovascular events and mortality rate during the year following ICU discharge.
- Trial name
- START-or-NOT (NCT05272878)
- Testing
- IRBESARTAN, tablet, 150 mg
- Where
- France
- Volunteers
- 508 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neurocognitive Dysfunction
Neuro-cognitive Function 1 Year Post ICU Discharge Among VV ECMO Survivors
In the past three years, in the general intensive care unit in Meir medical center, 25 patients were treated with ECMO, of which two patients were treated with VA ECMO and the rest with VV ECMO.
- Trial name
- NCT06224088
- Testing
- VV ECMO
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Meir Medical Center
Symptoms and Signs, Symptom Cluster
Patient Reported Symptoms the First Week After Intensive Care Unit Discharge and up to Hospital Discharge
The overall objective of this study is a) to increase knowledge about ICU patient's symptoms and symptom clusters during the first week after ICU discharge, and b) to identify cognitive, psychological, and physical symptoms and…
- Conditions
- Symptoms and Signs, Symptom Cluster, Follow-up Care, Critical Illness
- Trial name
- NCT05266118
- Where
- 2 sites in Norway
- Volunteers
- 177 people
- Sponsor
- Ostfold Hospital Trust
Fatigue
Fatigue One Year After ICU Discharge
The investigators contacted consecutive adult patients admitted to intensive care unit (ICU) and mechanically ventilated for at least 72 hours to invite them to an interview at hospital.
- Trial name
- NCT02684877
- Testing
- Questionnaire
- Volunteers
- 56 people
- Sponsor
- Università degli Studi di Ferrara
Sepsis
Long-term Assessment of Patients Treated in the ICU for Sepsis
This study is a prospective, observational cohort clinical registry designed to describe clinical and epidemiological characteristics and outcomes of adult patients hospitalized with sepsis.
- Trial name
- LAPTUS (NCT07502794)
- Testing
- Usual Care
- Where
- Brazil
- Volunteers
- 760 people
- Sponsor
- Hospital Israelita Albert Einstein
Premature Birth of Newborn, Family
GPS (Giving Parents Support): Parent Navigation After NICU Discharge
BACKGROUND: Annually >400,000 US newborns require neonatal intensive care unit (NICU) care.1/3 will require ongoing or specialty care after discharge.
- Conditions
- Premature Birth of Newborn, Family, Immature Newborn, Newborn Morbidity
- Trial name
- GPS (NCT02643472)
- Testing
- Parent Navigator, Care Notebook
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Children's National Research Institute
Post-acute COVID-19 Syndrome, Long-COVID
Sociodemographic, Clinical, Quality of Life and Health Care Conditions in COVID-19 Survivors.
Sociodemographic, Clinical, Quality of Life, and Health Care Conditions After Hospital Discharge in Patients Who Required Admission to the Intensive Care Unit for COVID-19 at the Hospital Universitario Nacional Between April 2020…
- Conditions
- Post-acute COVID-19 Syndrome, Long-COVID, COVID-19, Long COVID
- Trial name
- NCT05185674
- Testing
- Exposure: Coronavirus disease 2019 (COVID-19)
- Where
- Colombia
- Volunteers
- 114 people
- Sponsor
- Javier Eslava
Post Intensive Care Unit Syndrome
Long-term Follow up in Survivors of Critical Illness
Survivors of critical illness may suffer from persistent physical, cognitive and mental impairments, such as muscle weakness, dysfunction in the memory and executive domains, post-traumatic stress disorders, depression, and…
- Trial name
- NCT04608994
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia