Clinical trials: Post Mastectomy Complications
Postoperative Pain
Efficacy of Dexmedetomidine on Postoperative Analgesia
This prospective, randomized, double-blind study is designed to evaluate the postoperative analgesic efficacy of dexmedetomidine as an adjunct to ropivacaine in erector spinae block in patients undergoing radical mastectomy.
- Trial name
- EDPARMRCT (NCT05110339)
- Testing
- Ropivacaine plus dexmedetomidine, Ropivacaine
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- Universidad Autónoma de Tamaulipas
Pain, Breast Cancer
Effect of Ketalar to Prevent Postoperative Chronic Pain After Mastectomy
Prevalence of chronic pain after mastectomy is beyond 50% 3 months after surgery. This pain is related to a sensitization of the central nervous system through N-methyl-D-asparate (NMDA) receptors.
- Trial name
- NCT00129597
- Testing
- ketalar
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Breast Cancer, Surgery
Polyamine-free Diet to Prevent Post Surgery Hyperalgesia
After surgery, sensitization and hyperexcitability of central nervous system result in acute and long lasting postoperative pain.
- Trial name
- PoLyDOL (NCT00304850)
- Testing
- polyamine-free diet
- Where
- 5 sites in France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Bordeaux
Breast Cancer, Postoperative Pain, Acute
Rhomboid Intercostal Plane Block on Chronic Pain Incidence and Acute Pain Scores After Mastectomy
Rhomboid intercostal block is used to block lateral cutaneous branches of intercostal nerves between T3 and T9 dermatomes. RIB has been reported to be successful in attenuating acute pain following breast surgeries.
- Conditions
- Breast Cancer, Postoperative Pain, Acute, Postoperative Pain, Chronic, Neuropathic Pain
- Trial name
- NCT06019325
- Testing
- RIB
- Where
- Turkey (Türkiye)
- Volunteers
- 254 people
- Sponsor
- Muğla Sıtkı Koçman University
Surgery Date, Age
Quality of Life of Patients Who Have Undergone Bilateral Mastectomy
The investigators therefore aim to determine whether the type of mastectomy (preventive in a high-risk patient or therapeutic in a patient with a history of cancer), as well as the timing (immediate or delayed) and type of breast…
- Conditions
- Surgery Date, Age, BMI, Height
- Trial name
- RM BREAST Q (NCT07699913)
- Volunteers
- 115 people
- Sponsor
- University Hospital, Grenoble
Seroma Following Procedure, Infections
Single Versus Double Drains in the Axillary and Pectoral Regions After Modified Radical Mastectomy
Normally, after this surgery, skin is stitched in the usual simple way, with no quilting, and two drains are put in to remove serosa, one under the arm and one on the chest.
- Conditions
- Seroma Following Procedure, Infections, Pain, Postoperative
- Trial name
- SVDD (NCT07512141)
- Testing
- Double drains will be placed, A single drain will be placed
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sindh Institute of Urology and Transplantation
Postoperative Pain
Efficacy of Tramadol With Ropivacaine for Modified Pectoral Nerve Block in Breast Cancer Surgery
In this study the investigators will compare the post operative opoid consumption for patient undergoing modified radical mastectomy.
- Trial name
- NCT07775053
- Testing
- Pectoral Nerve Block
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sargodha Medical College
Postoperative Pain
Rhomboid Intercostal Block Versus Serratus Anterior Plane Block
evaluate and compare the impact of ultrasound guided rhomboid intercostal block versus serratus anterior plane block for analgesia after thoracodorsal artery perforator flap following partial mastectomy
- Trial name
- NCT05661279
- Testing
- general anesthesia, general anesthesia plus Rhomboid intercostal block, Serratus anterior plane block
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Breast Cancer, Post Operative Pain
Dexmedetomidine Versus Dexamethasone as Adjuncts in Erector Spinae Plane Block in Modified Radical Mastectomy
The aim of this study is to evaluate the analgesic efficacy and safety of adding dexmedetomidine versus dexamethasone to levobupivacaine in ultrasound guided ESPB for patients undergoing modified radical mastectomy
- Trial name
- NCT05447949
- Testing
- Adjuncts to levobupivacaine in Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Post-operative Pain
Postoperative Pain and Morphine Consumption After Mastectomy - Lyrica
This study will compare the effects of oral pregabalin with placebo on postoperative pain and morphine usage after mastectomy. Pregabalin is an anticonvulsant agent approved by the United States Food and Drug Administration (FDA)…
- Trial name
- NCT01391858
- Testing
- lyrica
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas Southwestern Medical Center
Post Mastectomy Complications
Intercostal Mulligan Moblization Post Mastectomy
the study is to evaluate the therapeutic efficacy of intercostal mulligan Mobilization in decreasing pain and improve ROM for shoulder dysfunction Patients post mastectomy.
- Trial name
- NCT07181980
- Testing
- Intercostal mulligan mobilization with shoulder abduction, Exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Pain, Postoperative, Non-Opioid Pain Management
Virtual Reality After Breast Reconstruction Surgery
This is a pilot study of virtual reality (VR) non-opioid management for women undergoing mastectomy and implant-based reconstruction.
- Conditions
- Pain, Postoperative, Non-Opioid Pain Management, Virtual Reality
- Trial name
- VR4BR (NCT03801616)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Complications
Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?
the investigators aim is to investigate and explore the effect 10 mg morphine added to local anesthetics in serratus anterior plane block for post mastectomy pain management after modified radical mastectomy in patients with…
- Trial name
- NCT02962024
- Testing
- Morphine Sulfate, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fatma Adel El sherif,MD
Postoperative Pain Following Modified Radical Mastectomy for Breast Cancer
Ultrasound-guided Thoracic Interfascial Plane Nerve Block Versus Erector Spinae Plane Block for Pain Control After Modified Radical Mastectomy
This study compares two methods of local pain control in patients undergoing Modified Radical Mastectomy, a common surgery for breast cancer( tumor in the breast) treatment.
- Trial name
- NCT06548646
- Testing
- Thoracic Interfascial Plane Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Safie ramez tewfeik abd el moneim
Breast Neoplasm Female, Complication of Radiation Therapy
Delayed-immediate Versus Delayed Breast Reconstruction in Breast Cancer Patients With Mastectomy and Radiation Therapy
In breast cancer patients treated by mastectomy and adjuvant post-mastectomy radiation therapy (PMRT) reconstruction is often delayed until 6 - 12 month after completion of chemotherapy and PMRT, due to high risk of complication.
- Conditions
- Breast Neoplasm Female, Complication of Radiation Therapy, Breast Implant; Complications
- Trial name
- NCT03730922
- Testing
- Delayed-immediate reconstruction, Delayed reconstruction
- Where
- 8 sites in Denmark
- Volunteers
- 590 people
- Sponsor
- Danish Breast Cancer Cooperative Group
Postmastectomy Lymphedema
Effect of Wii-console Based Exercise on Shoulder Range of Motion for Post-mastectomy Lymphedema Patients
PURPOSE: To determine the effect of wii-console based exercise on shoulder ROM of both sides for post-mastectomy patients, and highlighting the effect of dominancy.
- Trial name
- NCT05726656
- Testing
- traditional physical therapy session, wii console based exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Modified Radical Mastectomy, Post Operative Pain, Acute
Comparıson of Analgesıc Effıcacy of Dıfferent Volumes of Serratus Posterior Superıor Intercostal Plane Block After Modıfıed Radıcal Mastectomy Surgery
The aim of researchers is to compare the effects of three different local anesthetic concentrations and volumes on opioid consumption, postoperative analgesic efficacy, and pain scores during ultrasound-guided SPSIP blocks in…
- Conditions
- Modified Radical Mastectomy, Post Operative Pain, Acute, Facial Plane Blocks
- Trial name
- NCT07670078
- Testing
- Serratus Posterior Superior Intercostal Plane (SPSIP) block 40 ml of 0.1875% bupivacaine, Serratus Posterior Superior Intercostal Plane (SPSIP) 50 ml of 0.15% bupivacaine, Serratus Posterior Superior Intercostal Plane (SPSIP) 30 ml of 0.25% bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cumhuriyet University
Pain, Postoperative
Comparison of PECS II Block and Combined Serratus Anterior Plane Block to Reduce Acute Pain After Mastectomy
In this study, PECS II block or CSAB will be applied to patients who have had a modified radical mastectomy under general anesthesia for postoperative pain relief by using 30 ml of 0.25% bupivacaine .All patients will receive…
- Trial name
- NCT05961735
- Testing
- PECS II Block, Combined Serratus Anterior Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Mastectomy, Mastectomy Plus Axillary Lymph Node Dissection
Effect of Serratus and Pectoralis II Plane Block Versus Pectoralis II Alone on Acute Postoperative Pain After Mastectomy
The goal of this randomized controlled clinical trial is to determine whether adding a serratus anterior plane block (SAPB) to a pectoralis II (PECS II) block improves pain relief and reduces the need for opioids in adult women…
- Conditions
- Mastectomy, Mastectomy Plus Axillary Lymph Node Dissection, Nerve Block; Pain Medication, Pectoralis Nerve Block
- Trial name
- PECS (NCT07881237)
- Testing
- Serratus Anterior Plane Block (SAPB) group, Pectoral nerve block (PECS)
- Where
- Lebanon
- Volunteers
- 80 people
- Sponsor
- Lebanese American University
Postoperative Pain
Role of Transcrainal Direct Current Brain Stimulation in Acute and Chronic Post-mastectomy Pain Management
the role of transcranial magnetic stimulation over the primary motor cortex area on acute postoperative pain after breast cancer surgery and on the probability of developing chronic neuropathic pain.
- Trial name
- NCT03448315
- Testing
- tDCS
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University