Clinical trials: Post Menopausal Osteoporosis
Osteoporosis, Osteoporosis, Postmenopausal
3-Week Parathyroid Hormone-related Protein (PTHrP) Dose Escalation Study in Post-Menopausal Women
The main purpose of this study is to determine the safety and effectiveness of three week daily subcutaneous injections of Parathyroid Hormone-related Protein (1-36).
- Trial name
- NCT00222872
- Testing
- Parathyroid Hormone-related Protein
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Osteoporosis
Assessment of Anti-RANKL Antibody in Post-menopausal Women
This is a single-center, open-label, dose-escalating study to evaluate the safety, pharmacokinetics, immunogenicity, and preliminary efficacy of single dose subcutaneous injection of a fully human monoclonal antibody of receptor…
- Trial name
- NCT03242512
- Testing
- TK006
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jiangsu T-Mab Biopharma Co.,Ltd
Osteoporosis in Cushing's Syndrome, Osteoporosis in Post-menopausal Women
Cushing's Osteoporosis Specificities
Osteoporosis induced by glucocorticoids excess constitutes the main cause of secondary osteoporosis. Most of data available are provided from cohort studies of patients treated by corticosteroids, affecting among 1% of…
- Trial name
- SOCS (NCT03162068)
- Testing
- Osteodensitometry and pQCT
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Osteoporosis, Postmenopausal
A Study of 2 Different Formulations of Blosozumab (LY2541546) in Post Menopausal Women
The purpose of this study is to evaluate the tolerability of two different formulations of blosozumab in women who have reached menopause. This study will last approximately 12 weeks for each participant, not including screening.
- Trial name
- NCT02337387
- Testing
- Blosozumab
- Where
- 3 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Osteoporosis, Postmenopausal Bone Loss
Mediterranean Diet for Post-menopausal Women: Effects on Bone Turnover
The investigators propose a 24 week clinical research trial (12 week observational period followed by 12 week MedSD intervention) with feasibility of diet adoption and markers of bone turnover as the primary outcomes.
- Trial name
- MedSD (NCT01653275)
- Testing
- Mediterranean Diet
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- UConn Health
Osteoporosis, Postmenopausal
Quercetin's Effect on Bone Health and Inflammatory Markers
Quercetin is a plant-based flavonoid that is naturally found in many fruits and vegetables, and is considered to be a potent antioxidant with several expected health benefits such as anti-inflammatory effects and bone-conserving…
- Trial name
- NCT05371340
- Testing
- Quercetin (500 mg)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Bone Density, Osteopenia
The Influence of Vibration on Bone Mineral Density in Women Who Have Weak Bones After Menopause
This study will examine whether whole-body vibration slows down bone loss in healthy postmenopausal women with osteopenia. Whole-body vibration is a promising novel therapy that involves standing on a platform which produces…
- Conditions
- Bone Density, Osteopenia, Osteoporosis, Post-Menopause
- Trial name
- NCT00420940
- Testing
- Juvent 1000 Dynamic Motion Therapy (DMT) Platform
- Where
- Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Osteoporosis, Osteoporosis, Postmenopausal
A Study to Evaluate Food Effect on ONO-5920/YM529 Intermittent Formulation
The aim of the study is to evaluate the effects of food intake on the plasma concentration profile of YNO-5920/YM529 in post menopausal women.
- Conditions
- Osteoporosis, Osteoporosis, Postmenopausal, Bone Diseases
- Trial name
- NCT00965978
- Testing
- ONO-5920 / YM529
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Osteoporosis, Post-Menopausal
Combination Osteogenic Therapy in Established Osteoporosis
This study is designed to determine if combining parathyroid (PTH 1-34) with fluoride (MFPSR) therapy in a cyclic treatment regimen will: (1) produce a greater increase in bone density of the spine than would be produced by…
- Trial name
- NCT00018447
- Testing
- PTH 1-34, MFPSR-fluoride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Osteoporosis, Postmenopausal
Soluble Corn Fiber Effect on Bone Resorption in Post Menopausal Women
This study is designed to study the dose response effect of continuous Soluble Corn Fiber (SCF) intake over a 50 day period on bone resorption in healthy post menopausal women using the 41Calcium methodology.
- Trial name
- NCT02416947
- Testing
- 0 g SCF, 10g SCF, 20g SCF
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Purdue University
Osteoporosis, Postmenopausal
Dental Panoramic Radiographs to Screen for Post-menopausal Osteoporosis
Osteoporosis is a common disease that makes the bones fragile and easy to break. Osteoporotic fractures are a serious health problem resulting in pain, reduced mobility, increasing degree of dependence and sometimes death.
- Trial name
- OsteoPano (NCT03304743)
- Testing
- Dental panoramic radiograph
- Where
- Italy
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Parma
Osteoporosis, Osteoporotic Fracture of Vertebra
Development and Evaluation of an Exercise Intervention for Prevention of Vertebral Osteoporosis and Deformity in Postmenopausal Women
Osteoporotic fractures of the vertebrae (bones in the back) cause substantial pain and disability. Exercise could help to prevent these fractures by increasing bone strength and improving posture.
- Conditions
- Osteoporosis, Osteoporotic Fracture of Vertebra, Postural, Thoracic Kyphosis
- Trial name
- NCT04660825
- Testing
- A resistance band exercise programme, Control
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Osteoporosis
Role of T-cells in Post-Menopausal Osteoporosis
This is an observational study of women undergoing surgical menopause to determine whether T-cells play an important role in the etiology of post-menopausal osteoporosis.
- Trial name
- NCT00787904
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Atlanta VA Medical Center
Bone and Bones, Osteoporosis Risk
Nutritional Supplement and Bone Health in Post-Menopausal Women
The process of bone remodeling exhibits pronounced diurnal pattern that is important for bone health. A balanced rate of bone resorption is required to maintain bone health, a balance that can be disturbed during the lifecycle to…
- Conditions
- Bone and Bones, Osteoporosis Risk, Osteoporosis, Postmenopausal
- Trial name
- MBPS (NCT03337971)
- Testing
- MBPM
- Where
- Ireland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Osteoporosis in Post-menopausal Women, Vertebral Body Fractures
Effect of Muscle Stiffness on Vertebral Fractures in Women Over 60
This study aims to assess the quality of lumbar and abdominal core muscles through elastography and evaluate its impact on vertebral fracture risk.
- Conditions
- Osteoporosis in Post-menopausal Women, Vertebral Body Fractures, Balance, Postural
- Trial name
- NCT06687889
- Testing
- Elastography Measurements, Bone Mineral Density Measurement (DEXA), Berg balance scale
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Osteoporosis Risk
Investigation of the Effects of Physical Activity in Women at Risk of Osteoporosis
The goal of this clinical trial is to investigate the effects of the increase in the physical activity level of women at risk for osteoporosis in the post-menopausal period on the physical fitness, functional fitness age and…
- Trial name
- NCT06081764
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Post Menopausal Osteoporosis
A Study of Bone Turnover Markers in Post-Menopausal Women With Osteoporosis Treated With Monthly Boniva (Ibandronate)
This study will determine the rapidity of suppression of the bone resorption marker sCTX in post-menopausal women with osteoporosis.Other bone turnover markers will also be evaluated.
- Trial name
- NCT00303485
- Testing
- Vitamin D and calcium supplementation, ibandronate [Bonviva/Boniva]
- Where
- 10 sites in United States, Puerto Rico
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Osteoporosis, Postmenopausal
The Effects of Melatonin Treatment on Bone, Marrow, Sleep and Blood Pressure
Melatonin protects your bones while losing fat! This was previously demonstrated by our group. The mechanisms behind these findings are still elusive, and the aim of the present study is to assess the mechanisms.
- Trial name
- NCT04864509
- Testing
- Melatonin 10 MG
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Osteoporosis, Postmenopausal
Determination of Adipocyte Parameters in Iliac Crest Biopsies From Post Menopausal Women
To evaluate the effect of estrogen treatment on adipocytic and osteoblastic parameters by histomorphometrically measuring adipocyte volume (AV/TV) and adipocyte numbers in goldner's stained iliac crest bone biopsy specimens…
- Trial name
- NCT00443716
- Testing
- estrogen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Vitamin D Deficiency
Determination of Vitamin D Dose to Maintain Sufficiency Amongst Indian and Malay Women in the Tropics
Much research on vitamin D status has focused on seasonal variations in serum 25(OH)D levels in populations living at high altitudes and those of light-skinned Caucasian extraction, with little work done in multi ethnic…
- Trial name
- NCT02389179
- Testing
- Vitamin D3
- Where
- Malaysia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sharifah Faradila bt Wan Muhamad Hatta