Clinical trials: Post Menopause
Dehydration, Menstruation
Hydration & Female Life Stages
Female life stages including premenopausal, perimenopausal, postmenopausal, are characterized by changing concentrations and patterns of hormones.
- Conditions
- Dehydration, Menstruation, Pre-menopause, Peri-menopausal Women
- Trial name
- NCT07653620
- Testing
- electrolyte beverage
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Breast Cancer
HOBOE: A Phase 3 Study of Adjuvant Triptorelin and Tamoxifen, Letrozole, or Letrozole and Zoledronic Acid in Premenopausal Patients With Breast Cancer.
The HOBOE study was amended in November 2009, and, after reaching enrollment of the first 500 patients, the study began recruiting premenopausal patients only.
- Trial name
- HOBOE (NCT00412022)
- Testing
- tamoxifen, triptorelin, letrozole
- Where
- 20 sites in Italy
- Volunteers
- 1,294 people
- Sponsor
- National Cancer Institute, Naples
Menopause
A Survey Evaluating Prevalence, Severity and Associated Factors in East Asian Women With Moderate-to-severe Menopause-related Vasomotor Symptoms (MR-VMS)
The purpose of this study is to estimate the prevalence of Vasomotor Symptoms (VMS) and prevalence of moderate to severe VMS in peri-menopausal women and post-menopausal women aged 40-65 in East Asia (China, South Korea and…
- Trial name
- NCT04553029
- Testing
- No intervention
- Where
- 3 sites in China, South Korea and 1 more
- Volunteers
- 3,399 people
- Sponsor
- Astellas Pharma Singapore Pte. Ltd.
Osteoporosis
CR9112792, a Follow-up of Study CR9108963
The purpose of this study is to determine whether bone mineral density has increased in a subgroup of postmenopausal osteoporotic women from study CR9108963, between 6 and 12 months following cessation of ronacaleret therapy.
- Trial name
- NCT00891553
- Testing
- DXA
- Where
- 3 sites in Denmark, Norway
- Volunteers
- 171 people
- Sponsor
- GlaxoSmithKline
Healthy
Bioavailability Study of Letrozole Tablets 2.5 mg of Dr.Reddy's Under Fasting Conditions
The purpose of this study is to compare bioavailability in healthy, post menopausal women subjects under fasting conditions.
- Trial name
- NCT01375452
- Testing
- Letrozole
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Hot Flashes, Menopause Surgical
Acupuncture With/Without Self-acupressure for Post-oophorectomy Hot Flashes in BRCA Carriers
Risk-reducing surgery with salpingo-oophorectomy (RRSO) is the standard recommended treatment for all female carriers of BRCA genes 1 and 2.
- Trial name
- BRCA (NCT05331209)
- Testing
- Acupuncture, Acupuncture-Acupressure
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Shaare Zedek Medical Center
Postmenopausal Period, Fatigue
The Effect of Progressive Relaxation Exercises on Sleep Quality and Fatigue in Postmenopausal Period
The population of the study will be postmenopausal women who applied to the KETEM unit of a hospital in western Turkey for examination. This study is a two-group randomized controlled study.
- Conditions
- Postmenopausal Period, Fatigue, Sleep Quality
- Trial name
- NCT05483413
- Testing
- progressive relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Alzheimer Disease
Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease
The goal of this study is to examine whether the administration of estrogen to post-menopausal women and women with mild to moderate Alzheimer's disease will enhance their memory and their capacity for learning.
- Trial name
- NCT00006399
- Testing
- Donepezil, Estrogen, Progesterone
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- National Center for Research Resources (NCRR)
Vasomotor Symptoms
Treatment of Vasomotor Symptoms in Korean Post Menopausal Women
Study to demonstrate that the therapeutic efficacy of Angeliq® is better than placebo in Korean postmenopausal women with hot flushes and other climacteric symptoms. Safety and tolerability of Angeliq.
- Trial name
- NCT00651599
- Testing
- Angeliq (Drospirenone/17ß-estradiol, BAY86-4891)
- Where
- 4 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Bayer
Atherosclerosis, Chlamydia Infections
Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections
Hardening of the arteries (atherosclerosis) and heart disease are much more common in men than in women. However, as women grow older, especially after menopause the incidence of atherosclerosis and heart disease increases.
- Conditions
- Atherosclerosis, Chlamydia Infections, Cytomegalovirus Infections, Pneumonia, Bacterial
- Trial name
- NCT00001890
- Testing
- Estrogen therapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Menopause, Urinary Incontinence
Evaluation of the Safety and Performance of the MILTA GYNECO Vaginal Probe in Postmenopausal Women With Vaginal Atrophy
Vulvovaginal atrophy is common after menopause, with a significant negative effect on quality of life. Large cohort studies have reported the prevalence of vaginal dryness to be between 27% and 55% and dyspareunia between 32% and…
- Conditions
- Menopause, Urinary Incontinence, Atrophic Vaginitis
- Trial name
- SIVAM (NCT05058313)
- Testing
- Photobiomodulation
- Where
- 3 sites in France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Diabetes Mellitus, Type 2
A Research Study Looking Into the Effect of NNC0519-0130 on Blood Levels of a Birth Control Pill and Emptying of the Stomach in Women After Menopause
The purpose of the study is to investigate if NNC0519-0130 affects the blood levels of a birth control pill that contains the two hormones ethinylestradiol and levonorgestrel.
- Trial name
- NCT06513104
- Testing
- NNC0519-0130, Levonorgestrel + Ethinylestradiol, Paracetamol
- Where
- Germany
- Volunteers
- 47 people
- Sponsor
- Novo Nordisk A/S
Post Menopaused Female
Effects of Sensory Motor Training on Balance and Proprioception Among Post-Menopausal Obese Women
Postmenopausal obese women often have difficulties with balance and proprioception. Sensorimotor training is an important part of physical therapy interventions, with emerging evidence that it could be beneficial for…
- Trial name
- NCT04820738
- Testing
- Sensorimotor training exercises, Without Sensorimotor training exercises
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cardiovascular Diseases, Coronary Arteriosclerosis
Estrogen Replacement and Atherosclerosis (ERA) in Older Women
To determine if estrogen replacement therapy, with or without low dose progesterone, slows progression or induces regression of coronary atherosclerosis in postmenopausal women.
- Conditions
- Cardiovascular Diseases, Coronary Arteriosclerosis, Coronary Disease, Heart Diseases
- Trial name
- NCT00000549
- Testing
- estrogen replacement therapy, hormone replacement therapy, estrogens
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Post-menopausal Women
Investigation on the Sustained Effect of Anthocyanins on Endothelial Function in Postmenopausal Women
Anthocyanins are the most common polyphenols in berries and red wine, along with other flavonoids, phenolic acids, minerals and vitamins.
- Trial name
- Anthocyanins (NCT02517801)
- Testing
- Anthocyanin capsules
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Breast Cancer
Examination of Breast Cancer Cells of Pre-menopausal and Post-menopausal Women Before and After Exposure to Tamoxifen or Fulvestrant.
The purpose of this study is to microscopically examine breast cancer cells of pre-menopausal and post-menopausal women before and after exposure to one of the two commonly used breast cancer drugs, tamoxifen or fulvestrant.
- Trial name
- NCT02936206
- Testing
- Fulvestrant, Tamoxifen
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ovarian Cancer
Psychosexual Consequences of Risk-reducing Salpingo-oophorectomy
Short Rationale: Risk-reducing salpingo-oophorectomy (RRSO) is a mainstay in preventing ovarian cancer in BRCA1/2 mutation carriers, as ovarian cancer screening is ineffective in detecting ovarian cancer in an early and curable…
- Trial name
- PURSUE (NCT02372864)
- Testing
- Mindfulness based stress reduction (MBSR)
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- University Medical Center Groningen
Cardiovascular Diseases, Coronary Disease
Women's Estrogen/Progestin Lipid Lowering Hormone Atherosclerosis Regression Trial (WELL-HART)
To determine the effects, in postmenopausal women, of hormone replacement therapy on progression/regression of coronary heart disease, as measured by quantitative angiography.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000559
- Testing
- estrogen replacement therapy, hormone replacement therapy, estradiol
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Urinary Incontinence
A Comparison of Tolterodine and Placebo Treatments on Nocturnal Frequency and Sleep Quality in Women After Menopause.
This study is being done to compare frequency of urination during the night when women take tolterodine tablets vs. when they take placebo tablets.
- Trial name
- NCT00323635
- Testing
- tolterodine
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
CONcurrent vs SEqueNTial Adjuvant Treatments in Early Breast Cancer
Breast cancer is the most common form of cancer among women. For patients candidated for adjuvant chemotherapy and endocrine therapy the optimal timing for their has not been clearly defined yet.
- Trial name
- GIM10-CONSENT (NCT02918084)
- Testing
- Anastrozole or Letrozole or Exemestane
- Where
- 74 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy