Clinical trials: Post Menopause
Osteoporosis
Compliance and Persistence With Osteoporosis Treatment and Attitude Towards Future Therapy Among Post-menopausal Israeli Women During Drug Treatment or Drug Holiday
The purpose of the study is to provide information about the rate of response and persistence to drug therapies for osteoporosis.
- Trial name
- CONTINUITY (NCT01854086)
- Testing
- Questionnaires about compliance and persistence with bisphosphonates treatment
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Meir Medical Center
Parkinson's Disease
POETRY: Study of Estrogen Replacement Therapy in Postmenopausal Women With Parkinson's Disease
The primary objectives of the POETRY study are to assess the safety and tolerability of estrogen replacement therapy (ERT) in postmenopausal women with Parkinson's disease (PD) and to assess recruitment for a study of ERT in…
- Trial name
- NCT00234676
- Testing
- Premarin ®
- Where
- 6 sites in United States
- Volunteers
- 23 people
- Sponsor
- The Parkinson Study Group
Vaginal Atrophy, Vulvar Atrophy
VG101 Phase I/II to Treat Vulvar and Vaginal Atrophy in Post-Menopausal Women
To conduct a prospective, randomized, blinded, placebo controlled, dose escalation clinical trial in 4 cohorts of 10 postmenopausal women (total N=40) aged 45 to 65 years with at least one menopausal vaginal symptom, vaginal pH >…
- Trial name
- NCT00453089
- Testing
- VG101
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bionovo
Postmenopause
Tolerability & Safety of Premarin Vaginal Cream in Indian Postmenopausal Women
This post-marketing study will provide local safety and tolerance data on the use of Premarin® vaginal cream.
- Trial name
- NCT00484107
- Testing
- Conjugated Estrogen Cream (Premarin®)
- Volunteers
- 200 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Sexual Functions and Problems in the Adult
Effects of Tribulus Terrestris on Sexual Function in Post-menopausal Women
Objective: To study the effects of Tribulus terrestris on sexuality in postmenopausal women.
- Trial name
- NCT01407445
- Testing
- Tribulus terrestris
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Metastatic Breast Cancer
Trial Evaluating Dovitinib Combined With Fulvestrant, in Postmenopausal Patients With HER2- and HR+ Breast Cancer
This trial is designed to enroll postmenopausal patients with locally advanced or metastatic, HER2- and HR+ breast cancer not amenable to curative treatment by surgery or radiotherapy, and whose disease has progressed on or after…
- Trial name
- NCT01528345
- Testing
- Dovitinib, Fulvestrant
- Where
- 67 sites in United States, Argentina and 13 more
- Volunteers
- 97 people
- Sponsor
- Novartis Pharmaceuticals
Exercise-induced Joint Pain Stiffness and Cartilage Turnover
NEM® Versus Placebo on Exercise-induced Joint Pain, Stiffness, & Cartilage Turnover In Healthy, Post-Menopausal Women
This study is intended to evaluate the effect of the dietary supplement NEM® brand eggshell membrane versus placebo in reducing exercise-induced joint pain \& stiffness \& cartilage turnover in healthy post-menopausal women.
- Trial name
- NCT02751944
- Testing
- NEM
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ESM Technologies, LLC
Osteoporosis, Osteopenia
Isoflavones for Promoting Calcium Absorption and Preventing Bone Loss in Post Menopausal Women
Estrogen is a hormone that helps prevent calcium loss and bone breakdown. During menopause, estrogen levels decrease. Insufficient amounts of estrogen may lead to bone loss and possibly osteoporosis.
- Trial name
- NCT00244907
- Testing
- Genistein vs Risedronate
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Purdue University
Menopause, Menopause Hot Flashes
Effects of a Dietary Intervention Based on the Dietary Guidelines for the Brazilian Population on the Reduction of Menopausal Symptoms in Overweight and Obese Women
The menopausal transition is associated with significant hormonal changes that negatively impact many women's quality of life. Vasomotor symptoms, sleep disturbances, mood changes, and genitourinary symptoms are frequently…
- Conditions
- Menopause, Menopause Hot Flashes, Overweight , Obesity, Perimenopause, Climacteric Syndrome
- Trial name
- NCT07822230
- Testing
- Nutritional guidelines on healthy eating based on the Dietary Guidelines for the Brazilian Population in printed material and 5 in-person and virtual meetings, Nutritional guidelines on healthy eating based on the Dietary Guidelines for the Brazilian Population only in printed material
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Atherosclerosis
Study of Anti-atherosclerotic Activity of Karinat in Postmenopausal Women
The purpose of this study is to investigate the anti-atherosclerotic action of natural drug Karinat based on phytoestrogen-rich botanicals in postmenopausal women.
- Trial name
- PEARS-POST (NCT01742000)
- Testing
- Karinat
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institute for Atherosclerosis Research, Russia
Hormone Therapy
Hormone Therapy and Angiotensin-Dependent Arterial and Renal Vasoconstriction in Humans
1. to investigate the association between route of administration of exogenous estrogen (transdermal vs. oral) and cardiorenal risk in cisgender (gender identity aligning with sex at birth) and transgender (gender identity not…
- Trial name
- NCT05442463
- Testing
- Captopril Tablets, Iohexol
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Postmenopause, Sexual Function
On the Effect of a Hybrid Health Literacy Intervention on Sexual Function and Digital Health Literacy in Menopausal Women
This randomized controlled study will evaluate whether a hybrid health literacy education program improves sexual function and digital health literacy in postmenopausal women.
- Conditions
- Postmenopause, Sexual Function, Health Literacy, Digital Health Literacy
- Trial name
- EHHLI-MNP (NCT07839416)
- Testing
- Hybrid Health Literacy Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Vaginal Disease
Open Non-Comparative Clinical Trial Study To Evaluate The Performance And Safety Of Ainara®
This study evaluates treatment with the medical device Ainara on the improvement of vaginal dryness evaluated by Vaginal Health Index (VHI) and Visual Analog Scale (VAS) in comparison with the baseline condition.
- Trial name
- NCT04245358
- Testing
- Ainara
- Where
- Romania
- Volunteers
- 50 people
- Sponsor
- Italfarmaco
Osteoporosis, Metabolic Syndrome
Body Composition and Risk for Development of Pre-diabetes in Post-menopausal Chinese Women in Singapore
This project aims to ascertain that novel imaging and metabolic markers can be used to identify as well as to validate and improve the detection of Singapore-Chinese women at increased risk of diabetes.
- Trial name
- NCT03503552
- Where
- Singapore
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- JeyaKumar Henry
Menopause, Postmenopausal Bone Loss
Effects of Tibilone on Bone Density, Menopause Symptoms and Breast Density in Women After Prophylactic Oophorectomy
Women undergoing surgical menopause often experience marked menopausal side effects but are reluctant to use estrogen or other female hormones to ease the transition to menopause because of worries that the hormones may increase…
- Conditions
- Menopause, Postmenopausal Bone Loss, Breast Cancer
- Trial name
- NCT00165204
- Testing
- Tibolone
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Dana-Farber Cancer Institute
Menopause, Hormone Replacement Therapy, Post-Menopausal
Impact of Professional Societies' Recommendations on Practical Use of Hormone Replacement Therapy
This study is conducted in Europe. The aim of this study is to verify the therapeutic effects of low-dose hormone replacement therapy (HRT) in female patients over adequately long time period in normal clinical practice…
- Trial name
- NCT01487304
- Testing
- Marketed low dose hormone replacement therapy
- Where
- Czechia
- Volunteers
- 3,760 people
- Sponsor
- Novo Nordisk A/S
Healthy
A Food Effect Study With ZN-c5 in Healthy Post-Menopausal Subjects
This is a single-center, randomized, open-label, two-period, 2-way crossover food effect study to determine the comparative bioavailability of ZN-c5 under fed and fasting conditions, following single-dose administration of ZN-c5…
- Trial name
- NCT04561752
- Testing
- ZN-c5
- Where
- New Zealand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zeno Alpha Inc.
Post Menopausal Osteoporosis
Study of the Impact of Mother-of-pearl Nutritional Supplementation on the Prevention of Post-menopausal Osteoporosis
Post-menopausal osteoporosis and the resulting fractures are an important cause of disability and loss of independence. They also increase the risk of morbidity and mortality.
- Trial name
- NUTRANACRE (NCT05571514)
- Testing
- Mother-of-pearl, Calcium Carbonate
- Where
- 7 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Breast Cancer
Safety Study of the Hypo-fractionated (Large Doses) Radiation Therapy in Post-menopausal Women With Breast Cancers
The purpose of this study is to determine whether high dose of radiation therapy (RT) are effective over standard 6-week radiation treatment in patients with breast cancer
- Trial name
- NCT02883985
- Testing
- 6 Gy/ fraction
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Osteoporosis, Postmenopausal
Dental Panoramic Radiographs to Screen for Post-menopausal Osteoporosis
Osteoporosis is a common disease that makes the bones fragile and easy to break. Osteoporotic fractures are a serious health problem resulting in pain, reduced mobility, increasing degree of dependence and sometimes death.
- Trial name
- OsteoPano (NCT03304743)
- Testing
- Dental panoramic radiograph
- Where
- Italy
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Parma