Clinical trials: Post Operative, active
Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction
Effect of Coughing Exercises Versus Incentive Spirometry on Respiratory Function and Recovery in Children After Cardiac Surgery.
This study examines the effects of coughing exercises and incentive spirometry (IS) on lung function and recovery in children who undergo heart surgery.
- Conditions
- Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction, Postoperative Recovery After Cardiac Surgery
- Trial name
- CEXIS (NCT07405333)
- Testing
- Coughing Exercises, Incentive Spirometry, Standard Postoperative Care
- Where
- 4 sites in Iraq
- Volunteers
- 99 people
- Sponsor
- University of Baghdad
Postoperative Delirium
The Effect of Bupivacaine Liposome Preemptive Analgesia on Postoperative Pain and Delirium in Elderly Patients Undergoing Hip Fracture Surgery
To explore the effects of bupivacaine liposomes in preemptive analgesia for iliofascial block on postoperative pain and postoperative delirium in elderly patients with hip fractures, to optimize perioperative analgesia…
- Trial name
- NCT07066111
- Testing
- Tramadol, bupivacaine liposome (ultrasound-guided high iliofascial space block)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Dexmedetomidine, Lidocaine
Intravenous Lidocaine Plus Intratracheal Dexmedetomidine on Postoperative Sore Throat
Objective: The present study was to investigate the effect of intravenous lidocaine combined with intratracheal dexmedetomidine on postoperative sore throat in patients undergoing thyroid cancer surgery.
- Conditions
- Dexmedetomidine, Lidocaine, Sore Throat
- Trial name
- NCT06952309
- Testing
- Intracheal dexmedetomidine, Intravenous lidocaine, Intravenous lidocaine combined with intracheal dexmedetomidine
- Volunteers
- 144 people
- Sponsor
- Anqing Municipal Hospital
Hip Osteoarthritis, Hip Injuries
Positioning for Hip Arthroscopic Surgery to Reduce Postoperative Numbness
Compared to the knee and shoulder, the hip joint leaves relatively little space to maneuver arthroscopic instruments and camera.
- Conditions
- Hip Osteoarthritis, Hip Injuries, Hip Sprain, Hip Strain
- Trial name
- NCT05038709
- Testing
- The Pink Pad Hip Kit
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Postoperative Complications
Intraoperative Fluid Management Guided by Internal Jugular Vein on Postoperative Complications in Abdominal Surgeries
This study investigates the role of respiratory variation in the internal jugular vein as a tool for intraoperative fluid management during abdominal surgeries under general anesthesia.
- Trial name
- NCT07041021
- Testing
- Respiratory variation of the Internal Jugular Vein (IJV)
- Where
- 2 sites in Egypt
- Volunteers
- 84 people
- Sponsor
- Suez Canal University
Chronic Low-back Pain, Herniated Disc
LISA Post Market Clinical Follow-Up Study: Documentation of Clinical Outcomes After Surgery With LISA Implant
The study is a post-market surveillance study of the Lumbar Implant for Stiffness Augmentation (LISA), a medical device, which is used to treat low-back pain that accompanies degenerative lesions of grades II, III, and IV…
- Conditions
- Chronic Low-back Pain, Herniated Disc, Degenerative Disc Disease, Lumbar Canal Stenosis
- Trial name
- LISA-PMCF (NCT04631133)
- Testing
- Lumbar Implant for Stiffness Augmentation (LISA)
- Where
- 5 sites in Denmark, France and 1 more
- Volunteers
- 136 people
- Sponsor
- BACKBONE
Periprosthetic Joint Infection (PJI), Periprosthetic Knee Infection
Analysis of the Etiopathogenesis of Postoperative Complications in Orthopedic Patients Using Knee and Hip Arthroplasty as an Example
Relevance and Rationale Due to the widespread development of high-tech medical care in traumatology and orthopedics for patients with severe forms of hip and knee osteoarthritis and aseptic necrosis, and the increasing number of…
- Conditions
- Periprosthetic Joint Infection (PJI), Periprosthetic Knee Infection, Periprosthetic Hip Infection, Diagnostic
- Trial name
- NCT07813832
- Where
- Russia
- Volunteers
- 750 people
- Sponsor
- People's Friendship University of Russia
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Postoperative Neurocognitive Dysfunction, Postoperative Neurocognitive Disorder
The Role of Neuroinflammation on Neurocognitive Outcome in Cardiac Surgery
RATIONALE: Postoperative cognitive changes are common after cardiac surgery and can be categorised into three main types: postoperative delirium (POD), delayed neurocognitive recovery (DNCR) and postoperative neurocognitive…
- Conditions
- Postoperative Neurocognitive Dysfunction, Postoperative Neurocognitive Disorder, Cardiac Surgery, Major Surgery Under General Anesthesia
- Trial name
- INOCS (NCT07200726)
- Testing
- Observational study design - no intervention
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Ziekenhuis Oost-Limburg
Inguinal Hernia, Postoperative Pain
Ultrasound-Guided Ilioinguinal-Iliohypogastric Nerve Block Following Spinal Anesthesia Comparing Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Unilateral Inguinal Hernia Repair
This study evaluates and compares the pain-relieving efficacy and safety of adding either dexmedetomidine or nalbuphine to bupivacaine in an ultrasound-guided ilioinguinal-iliohypogastric nerve block for patients undergoing…
- Trial name
- NCT07837492
- Testing
- Bupivacaine, Nalbuphine, Dexmedetomidine
- Volunteers
- 102 people
- Sponsor
- Assiut University
Postoperative Delirium, Postoperative Cognitive Dysfunction
Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool
This observational cohort study is designed to validate the CogCheck application as a risk prediction tool for postoperative delirium in patients undergoing cardiac surgery.
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Cognitive Decline, Cognitive Impairment
- Trial name
- CogCheck-Valid (NCT03360838)
- Testing
- CogCheck
- Where
- Switzerland
- Volunteers
- 475 people
- Sponsor
- University Hospital, Basel, Switzerland
Morbid Obesity
Bougie Sleeve Trial
Staple-line leak is the most frequent and incapacitating complication after laparoscopic sleeve gastrectomy (LSG). The aim of this prospective randomized trial is to compare the staple-line leak rate after LSG according to the…
- Trial name
- BOUST (NCT02937649)
- Testing
- Laparoscopic sleeve gastrectomy using 48-Fr bougie, Laparoscopic sleeve gastrectomy using standard care bougie
- Where
- 12 sites in France
- Volunteers
- 1,658 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Orthognathic Surgical Site Infection
Antibiotics for Prevention of Infection Following Orthognathic Surgery
Orthognathic surgery describes a group of procedures aimed at correcting developmental or acquired deformities of the jaws and facial skeleton.
- Trial name
- NCT05852158
- Testing
- Cefazolin 2 GM Injection, Cefazolin Injection
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Abdul El-Rabbany
Postoperative Pain, Acute, Postoperative Complications
Minimally Invasive Esophagectomy Pain Control Trial
A pilot randomized controlled trial comparing intercostal nerve blocks, cryo-ablation plus intercostal nerve blocks, and serratus plane catheter plus intercostal nerve blocks in patients undergoing esophagectomies with minimally…
- Trial name
- NCT05906134
- Testing
- Local intercostal nerve block, Cryo-analgesia and intercostal nerve block, Serratus plane catheter blocks and intercostal nerve blocks
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Swedish Medical Center
Colon Adenocarcinoma, Microsatellite Stable Colon Carcinoma
Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer
This phase II/III trial compares the effect of the combination of encorafenib and cetuximab to usual care (patient observation) for reducing the chance of cancer recurrence after standard surgery and chemotherapy in patients with…
- Conditions
- Colon Adenocarcinoma, Microsatellite Stable Colon Carcinoma, Stage IIB Colon Cancer AJCC v8, Stage IIC Colon Cancer AJCC v8
- Trial name
- NCT05710406
- Testing
- Encorafenib, Cetuximab, Biospecimen Collection
- Where
- 202 sites in United States
- Volunteers
- 1 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Enhanced Recovery After Surgery in a Pediatric Population
Dex +/- Caffeine Sedation in a Post-MRI Recovery in a Pediatric Population
Dexmedetomidine (Dex), a selective α2-adrenergic receptor agonist, is the most used sedative for procedural sedation in children and in pediatric Intensive Care Unit (PICU) because it is associated with less respiratory…
- Trial name
- NCT06538584
- Testing
- Caffeine citrate 15mg/kg, 0.9% Sodium Citrate
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Calcaneal Fractures
Sustentaculum Tali Screw Fixation Mode and Postoperative Foot-Ankle Function in Calcaneal Fractures
This is an observational, ambidirectional cohort study. Calcaneal fractures are the most common tarsal bone fractures, and most are intra-articular fractures involving the subtalar joint.
- Trial name
- NCT07822698
- Testing
- Screw Tip Position Relative to the Sustentaculum Tali
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Peking University Third Hospital
Postoperative Complications, Thoracic Surgery
Wearable Device-Based Early Warning of Postoperative Complications in Thoracic Surgery
After thoracic surgery, some patients may develop complications such as lung infection, abnormal heart rhythm, fluid around the lung, prolonged air leak, wound infection, emergency department visits, or hospital readmission.
- Conditions
- Postoperative Complications, Thoracic Surgery, Perioperative Monitoring
- Trial name
- wearable (NCT07646730)
- Testing
- Wearable device-based perioperative monitoring
- Where
- China
- Volunteers
- 650 people
- Sponsor
- Tongji Hospital
Postoperative Pain
Comparison of Analgesic Effects of TAP Block and RSB in RALPs
In this research, we aim to compare the postoperative analgesic efficacy of these two peripheral blocks in patients undergoing RALP who have received preoperative TAP block and RSB block.
- Trial name
- NCT06681571
- Testing
- TAP Block, RSB
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Postoperative Pain
QL Block Versus EO Plane Block for Analgesia After Open Nephrectomy
This prospective randomized clinical trial aims to compare two ultrasound-guided regional anesthesia techniques, the transmuscular quadratus lumborum (QL) block and the external oblique (EO) plane block, for pain relief after…
- Trial name
- NCT07787221
- Testing
- Quadratus Lumborum Block (QLB), External Oblique Plane Block
- Where
- 2 sites in Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
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