Clinical trials: Post Operative Complications
Osteoarthritis
Bandgrip vs Traditional Sutures TJA
Total Joint Arthroplasty (TJA) has become one of the most performed elective procedures. While the results of this procedure are often consistent with high patient satisfaction and return-to-function, wound-related complications…
- Trial name
- NCT05166642
- Testing
- Bandgrip Micro-Anchor Wound Closure, Suture closure
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Center for Innovation and Research Organization
Postoperative Delirium, Hip Fractures
Intrathecal Dexmedetomidine and Postoperative Delirium in Elderly Hip Fracture Surgery
Postoperative delirium (POD) is a common and serious complication in elderly patients undergoing surgical repair for hip fractures, often triggered by acute pain, surgical stress, neuroinflammation, and opioid consumption.
- Trial name
- NCT07810556
- Testing
- Dexmedetomidine, Hyperbaric Bupivacaine with Normal Saline
- Volunteers
- 130 people
- Sponsor
- Assiut University
Emergence Agitation
Comparison of Emergence Agitation Between Sevoflurane and Desflurane Anesthesia After Orthognathic Surgery
Emergence agitation is a major concern in patients undergoing orthognathic surgery. The patients may experience the sense of suffocation during emergence due to nasotracheal intubation and orofacial edema.
- Trial name
- NCT01878656
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Chung-Ang University Hospital
Hypospadias, Complication,Postoperative
Evaluation of TIP Urethroplasty With Spongioplasty-Dartosoraphy Reinforcement in Pediatric Hypospadias
The study aimed to evaluation of Tubularized incised palate urethroplasty with spongioplasty-dartosoraphy reinforcement (group A) through comparing of functional and cosmetic results of this technique with the conventional TIP…
- Trial name
- NCT05960123
- Testing
- Tubularized Incised Plate (TIP) urethroplasty
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Al-Azhar University
Abdominal Surgery
Effects of ACBT and Blow Bottle Technique in Patients With Abdominal Surgeries Under General Anesthesia
A postoperative pulmonary complication (PPC) is the most common serious complication after Abdominal surgery under GA which lead to longer hospital stays and have deleterious outcomes on lung volumes, mucociliary clearance…
- Trial name
- NCT06454305
- Testing
- Active cycle of breathing technique, Blow Bottle Technique
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Postoperative Pain
Femoral or Sciatic Nerve Block to Provide Analgesia After Proximal Tibial Osteotomy
Proximal tibial osteotomy is associated with moderate to severe postoperative pain. The proximal part of the tibia is innervated by branches from the femoral nerve anteriorly and the sciatic nerve posteriorly.
- Trial name
- NCT05728294
- Testing
- Femoral nerve block with ropivacaine 0.5%, 20 ml, Sciatic nerve block with ropivacaine 0.5%, 20 ml
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Intrauterine Adhesion
Safety and Efficacy of Intrauterine Biological Barrier on Postoperative Adhesion After Hysteroscopic Adhesiolysis
To evaluate the safety and efficacy of Intrauterine Biological Barrier developed and produced by Chengdu TopRegMed Medical Technology Co., Ltd on postoperative adhesion after Hysteroscopic Adhesiolysis.
- Trial name
- NCT05475756
- Testing
- Intrauterine Biological Barrier, Intrauterine Adhesion Barrier Gel
- Where
- 6 sites in China
- Volunteers
- 264 people
- Sponsor
- Beijing Tiantan Hospital
Ventral Hernia, Incisional Hernia
Cryoneurolysis for Abdominal Wall Relaxation Prior to Ventral Hernia Repair
The goal of this clinical trial is to learn if cryoneurolysis, a targeted cold therapy applied to nerve branches, can relax the muscles of the abdomen to facilitate surgical repair of abdominal wall hernias.
- Conditions
- Ventral Hernia, Incisional Hernia, Hernia, Hernia Abdominal Wall
- Trial name
- NCT07874724
- Testing
- Cryoneurolysis
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of South Florida
Postoperative Complications
Use of Integrated Pulmonary Index to Predict Post-Operative Respiratory Adverse Events in High Risk Patients
The Capnostream 20p monitor by Medtronic is FDA-cleared and consists of a monitor which measures real-time respiratory status based on respiratory rate, pulse rate, pulse oximetry (SpO2) and end tidal carbon dioxide (etCO2) with…
- Trial name
- NCT03275324
- Testing
- Capnostream20p
- Volunteers
- 600 people
- Sponsor
- Stony Brook University
Postoperative Pain
Analgesic Efficacy of Fascia Iliaca Compartment Block Compared With Intrathecal Nalbuphine for Hip Surgery Under Spinal Anesthesia
It is already known that fascia iliaca compartment block and intrathecal nalbuphine are very effective ways in postoperative pain control in patients having hip surgeries.
- Trial name
- NCT06818396
- Testing
- US-guided fascia iliaca compartment block (FICB) and spinal anesthesia, Intrathecal nalbuphine and spinal anesthesia, Spinal anesthesia
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Dental Pulp Necrosis, Pulpitis
Metagenomic Analysis and Postoperative Pain in Infected Root Canals Using Different Irrigation Protocols
Achieving effective root canal disinfection while minimizing postoperative pain is a critical goal in endodontic therapy. Advanced irrigation protocols, such as ultrasonic activation, laser activation, negative pressure…
- Trial name
- NCT07546773
- Testing
- Ultrasonic Irrigation Activation, Laser-Activated Irrigation, Mechanical Irrigation Activation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Post Operative Nausea and Vomiting
Effects of Preoperative Carbohydrate Rich Drinks on Immediate Postoperative Outcome in Total Knee Arthroplasty
The aim of this study is to investigate the effect of preoperative carbohydrate rich drinks on postoperative nausea and vomiting in total knee arthroplasty. This is a prospective, double blinded, randomized controlled trial.
- Trial name
- PONV (NCT03380754)
- Testing
- Nutricia preOp
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Diastolic Dysfunction
Pre-operative Focused Transthoracic Echocardiography for Prediction of Post-operative Cardiac Complications
The extent focused transthoracic echocardiography when done pre-operatively to patients admitted for elective surgery and suspected to be at risk of cardiac disease specially the geriatric population can affect perioperative…
- Trial name
- NCT04114474
- Testing
- TRANSTHORACIC ECHOCARDIOGRAPY
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- South Egypt Cancer Institute
Surgical Site Infection, Length of Stay
Prevena to Prevent Surgical Site Infection After Emergency Abdominal Laparotomy
Post-operative wound complications in abdominal surgery have a major impact on patient outcomes and the real impact of Closed incision negative pressure therapy (CINVt) is not clear in the literature moreover concerning its…
- Conditions
- Surgical Site Infection, Length of Stay, Seroma, Hematoma
- Trial name
- CiPNT/SSI (NCT04496180)
- Testing
- Closed incision negative pressure therapy versus standard dressing after emergency abdominal laparotomies
- Volunteers
- 334 people
- Sponsor
- University Hospital, Geneva
Post Operative Pain
A Comparative Study of Intrathecal Dexmedetomidine and Fentanyl As Additives to Bupivacaine in Pott's Fracture
The aim of this study is to compare the addition of intrathecal dexmedetomidine or fentanyl as adjuvants to hyperbaric bupivacaine in the onset and duration of sensory and motor block, and postoperative analgesia.
- Trial name
- NCT06502262
- Testing
- Bupivacaine Hydrochloride, Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Cancer Surgery, Prehabilitation
Preoperative Physical Exercise, Nutritional Support, and Psychological Intervention (Multimodal Prehabilitation) to Strengthen Patients' Overall Health and Reduce Postoperative Complications
In this prospective, randomized, controlled trial patients undergoing major gastrointestinal cancer surgery will be exercised (intervention group) 4 weeks before surgery with a high-intensity interval training (HIIT).
- Trial name
- PREHAB (NCT07389746)
- Testing
- Multimodal Prehabilitation
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- University Hospital of Cologne
Postoperative Nausea and Vomiting, Vomiting
Dexamethasone for the Treatment of Established Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) are frequent after surgery and anaesthesia. Dexamethasone is widely used as antiemetic for the prevention of PONV.
- Trial name
- DexPonv (NCT01975727)
- Testing
- Dexamethasone 3 mg, Dexamethasone 6 mg, Dexamethasone 12 mg
- Where
- 4 sites in Switzerland
- Volunteers
- 256 people
- Sponsor
- University Hospital, Geneva
Foot, Sleep
Effect of Footbath on Pain Severity and Sleep Quality
The goal of this clinical trial is to examine the effect of hot water foot bath on the patients' pain severity and sleep quality levels on the night of the lumbar degenerative disc surgery.
- Conditions
- Foot, Sleep, Pain
- Trial name
- NCT05658783
- Testing
- Hot water foot bath
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Trakya University
Phantom Limb Pain
Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study
When a limb is traumatically severed, pain perceived in the part of the body that no longer exists often develops. This is called "phantom limb" pain, and is different from "stump" pain, which is pain within the part of the limb…
- Trial name
- DoD-PLP-Tx (NCT01824082)
- Testing
- Perineural infusion [continuous peripheral nerve block(s)]
- Where
- 4 sites in United States
- Volunteers
- 144 people
- Sponsor
- University of California, San Diego
Acute Kidney Injury
Association Between Postoperative Administration of L-Arginine and CSA-AKI
To investigate the association between the the early administration of L-Arginine after CPB-assisted cardiac surgery and the incidence of CS-AKI in adult patients. To test if it can reduce the incidence of post-operative AKI.
- Trial name
- NCT06248359
- Testing
- L-Arginine hydrochloride
- Where
- China
- Volunteers
- 5,135 people
- Sponsor
- Xijing Hospital
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