Clinical trials: Post Operative Ileus, open to volunteers
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Postoperative Ileus, Bowel Paralysis
Gastrointestinal Stimulation As a Treatment of Postoperative Ileus Following Extensive Surgery
The goal of this clinical trial is to investigate the effect of gastrointestinal stimulation with a pacemaker on the length of postoperative bowel paralysis in patients undergoing major abdominal surgery due to metastasizing…
- Trial name
- STIMULATE (NCT05752071)
- Testing
- Gastric electrical stimulation
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Colon Cancer, Splenic Flexure Mobilization
Surgical Outcomes in Splenic Flexure Cancers: A Multicenter Comparison of Segmental vs. Extended Hemicolectomy (SPARROW Study)
SPARROW Study: Surgical Outcomes in Splenic Flexure Cancer Colonic cancers located at the splenic flexure where the transverse colon turns into the descending colon are uncommon and represent less than 10% of all colorectal…
- Conditions
- Colon Cancer, Splenic Flexure Mobilization, Right Hemicolectomy, Left Hemicolectomy
- Trial name
- SPARROW (NCT07289568)
- Testing
- Colectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Acibadem University
Ileus Postoperative, Gastrointestinal Function
Oral Lactulose for Gastrointestinal Recovery After Complex Appendectomy
This is a prospective, triple-blind, placebo-controlled, single-center randomized clinical trial to evaluate the efficacy and safety of early oral lactulose for promoting postoperative gastrointestinal functional recovery in…
- Conditions
- Ileus Postoperative, Gastrointestinal Function, Complicated Appendicitis
- Trial name
- NCT07589465
- Testing
- Lactulose oral solution
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Nanchong Central Hospital
Postoperative Ileus
Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery
A double blind, placebo controlled, randomized control trial studying the safety and efficacy of pyridostigmine as a rescue therapy for postoperative ileus.
- Trial name
- PESTI (NCT05334485)
- Testing
- Pyridostigmine Bromide
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stefan Holubar MD MS FACS, FASCRS
Cesarean Section, Postoperative Nausea and Vomiting (PONV)
Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section
Spinal anesthesia for elective cesarean section is frequently associated with hemodynamic instability and postoperative complications such as postoperative nausea and vomiting (PONV) and delayed gastrointestinal recovery.
- Conditions
- Cesarean Section, Postoperative Nausea and Vomiting (PONV), Postdural Puncture Headache (PDPH), Postoperative Ileus
- Trial name
- NCT07440667
- Testing
- Restrictive intraoperative crystalloid fluid strategy (≤3 mL/kg/h), Liberal intraoperative crystalloid fluid strategy (>3 mL/kg/h)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Nigde Omer Halisdemir University
Colorectal Surgery
Study of Postoperative Ileus in Digestive Surgery
Post-operative ileus is a temporary stoppage of bowel function following surgery. Indeed it can occur in 20% of cases during post-operative follow-up of bowel surgery.
- Trial name
- IPCID (NCT06018961)
- Testing
- Post-operative ileus surgery
- Where
- 2 sites in France
- Volunteers
- 161 people
- Sponsor
- University Hospital, Toulouse
the Intraoperative Hypotension
Intraoperative Hypotension and Metabolomics in Major Upper Gastrointestinal Surgery
We will investigate the effect of hypotension prediction index guidance on intraoperative hypotension and metabolomics in patients undergoing major upper gastrointestinal surgery
- Trial name
- NCT05828862
- Testing
- hypotension prediction index guidance
- Where
- Taiwan
- Volunteers
- 85 people
- Sponsor
- National Taiwan University Hospital
Post-Operative Ileus (POI)
At-Home Bowel Stimulation
Postoperative ileus (POI) is a common complication after ileostomy closure and is associated with patient discomfort, delayed return of bowel function, prolonged hospital stay, and increased healthcare costs.
- Trial name
- NCT07574437
- Testing
- At-home bowel stimulation
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- The Cleveland Clinic
Bowel Sounds, Colorectal Cancer
The Value of Bowel Sounds in Evaluating Postoperative Intestinal Function Recovery in Colorectal Cancer Patients
This study enrolls patients scheduled to undergo curative surgery for colorectal cancer. Bowel sounds will be assessed preoperatively and postoperatively.
- Conditions
- Bowel Sounds, Colorectal Cancer, Intestinal Obstruction, Postoperative Ileus
- Trial name
- BRIEF (NCT07705139)
- Testing
- colorectal surgery
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Zhongnan Hospital
Post Operative Patients
The Food Network Effect
The goal of this clinical trial is to learn if exposure to food related visual stimuli during the postoperative period can improve gastrointestinal recovery after abdominal surgery in adult patients.The main questions it aims to…
- Trial name
- NCT07618559
- Testing
- Food Related Visual Stimuli Exposure
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Casey Morehouse, DO
Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus
Neuromuscular Blocking Agents on Gastrointestinal Function Following Colorectal Surgery
This study is a clinical research project conducted at Xijing Hospital to compare the effects of two different neuromuscular blockade reversal strategies on the recovery of gastrointestinal (GI) function after colorectal surgery.
- Conditions
- Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus, Colorectal Surgery
- Trial name
- NCT07271875
- Testing
- Neostigmine + Atropine, Sugammadex
- Volunteers
- 560 people
- Sponsor
- Xijing Hospital
Postoperative Ileus
Dexamethasone in the Prevention of Post-spinal Paralytic Ileus After Cesarean Section
Postoperative ileus is a perplexing problem for clinical surgeons. It occurs not only after abdominal surgery but also after any surgery that requires general anesthesia.
- Trial name
- NCT05654649
- Testing
- 0.9%sodium chloride, Dexamethasone
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Ileus Postoperative
Effect of Lollipop on Postoperative Gastrointestinal Recovery in Children
Postoperative ileus is common in children. There are various method to prevent postoperative ileus. In this study, the investigators will explore the role of sucking lollipop after operation on the recovery of gastrointestinal…
- Trial name
- NCT06108011
- Testing
- Lollipop
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Delay in GI Recovery/Postoperative Ileus (POI)
TU-100 for Accelerating GI Recovery After Major Abdominopelvic Surgery (RC & CAWR)
This Phase 2, multicenter, randomized, double-blind, placebo-controlled master protocol study will evaluate the safety and efficacy of TU-100, adjunctive to an Enhanced Recovery After Surgery (ERAS) pathway, for accelerating…
- Trial name
- NCT07765589
- Testing
- TU-100
- Volunteers
- 240 people
- Sponsor
- Tsumura USA
Pain, Postoperative, Postoperative Ileus
Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal Surgery
Title: Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal Surgery: A Multicenter, Randomized, Controlled Trial The goal of this clinical trial is to evaluate the effectiveness and safety of tegileridine…
- Trial name
- NCT07412223
- Testing
- Tegileridine, Morphine
- Where
- 3 sites in China
- Volunteers
- 152 people
- Sponsor
- Xiangya Hospital of Central South University
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Acute Abdomen, Ileus
Rectus Sheath Catheters Following Midline Laparotomy
Rectus sheath catheters (RSC) are used for postoperative analgesia following midline laparotomies. Local anesthetics are applied to the posterior rectus sheath via the RSC.
- Conditions
- Acute Abdomen, Ileus, Colorectal Carcinoma
- Trial name
- NCT07099924
- Testing
- Ropivacaine 0.2%, Saline 0.9%
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Asklepios Kliniken Hamburg GmbH
Postoperative Ileus
Use of Beetroot Juice to Protect Against Postoperative Ileus Following Colorectal Surgery: BEET IT Study
The goal of the BEET IT study is to examine if preoperative intake of beetroot juice can ameliorate gastrointestinal (GI) recovery after colorectal surgery and thereby help to reduce the duration of postoperative ileus (POI) and…
- Trial name
- BEET IT (NCT05133024)
- Testing
- concentrated beetroot juice
- Where
- 6 sites in Belgium
- Volunteers
- 170 people
- Sponsor
- University Hospital, Ghent
Postoperative Ileus, Colorectal Cancer Control and Prevention
Implementation of an Efferent Loop Stimulation Protocol Prior to Ileostomy Closure at La Paz University Hospital
Stoma creation is a common surgical procedure, employed in certain contexts within general surgery, particularly in colorectal and emergency surgery.
- Conditions
- Postoperative Ileus, Colorectal Cancer Control and Prevention, Stoma - Ileostomy
- Trial name
- NCT06974500
- Testing
- Daily efferent limb stimulation for at least two weeks prior to surgery using saline solution and a thickering agent
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Hospital Universitario La Paz