Clinical trials: Post Operative Nausea and Vomiting
Postoperative Nausea, Postoperative Vomiting
The Impact of Nasogastric Tube Gastric Decompression on Postoperative Nausea and Vomiting in Orthognathic Surgery
This study will compare the incidence of postoperative nausea and vomiting during the first 24 hours following corrective jaw surgery (orthognathic surgery) in patients with and without nasogastric tube gastric decompression.
- Trial name
- NCT06422793
- Testing
- No NG tube gastric decompression
- Where
- Canada
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Emesis, Postoperative, Maxillofacial Abnormalities
Effects of Antiemetic Agents in Orthognathic Surgery Patients
In an effort to prevent or treat consistently high rates of PONV following maxillofacial operations, several medications, techniques and multimodal protocols have been studied.
- Trial name
- NCT06454825
- Testing
- Intravenous drug
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Postoperative Nausea and Vomiting
Effects of Fluid Infusion on Postoperative Vomiting in Pediatric Patients Undergoing Otorhinolaryngological Surgery
Otorhinolaryngological surgery is one of the commonly applied procedures surgical treatments of children in the world. Postoperative vomiting (POV) is an important part of the management of pediatric anesthesia in this surgery…
- Trial name
- FLUIDVOMIT (NCT03485443)
- Testing
- %0.9 NaCl 10ml/kg, %0.9 NaCl 20ml/kg
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Motion Sickness, Postoperative Nausea and Vomiting
Gynecologic Endoscopic Surgery of Female Motion Sickness Patients
The goal of this clinical trial is to compare the analgesic effect of sufentanil and ibuprofen and the incidence of vomiting, and to choose better postoperative analgesic drugs for motion sickness patients.in describe participant…
- Conditions
- Motion Sickness, Postoperative Nausea and Vomiting, Ibuprofen
- Trial name
- NCT06232785
- Testing
- Ibuprofen, sufentanil
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Jilin University
Nausea, Postoperative
Effects of Aromatherapy on Nausea Levels
Aromatherapy is the therapeutic use of essential oils from plants for the improvement of physical, emotional, and spiritual well-being. Healthcare providers play an important role in improving the care of patients with nausea.
- Trial name
- NCT04882501
- Testing
- QUEASEEase aromatherapy quick tab
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Postoperative Nausea, Vomiting
Postoperative Nausea and Vomiting in Laparoscopic Abdominal Surgery
The goal of this clinical trial is to compare frequency with postoperative nausea and vomiting in ASA( American Society of Anesthesiologists) I, II patients undergoing laparoscopic surgery.
- Trial name
- PONV (NCT05632224)
- Testing
- Aprepitant, Granisetron
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baskent University
Postoperative Nausea and Vomiting
Intranasal Lidocaine for Prevention of Postoperative Nausea and Vomiting.
Postoperative nausea and vomiting (PONV) are common and continue to be persistent problems following general anesthesia. Intranasal lidocaine has been used for the treatment of migraine.
- Trial name
- NCT04810494
- Testing
- 2% Lidocaine HCl topical solution, 0.9% Sodium chloride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Postoperative Nausea and Vomiting
Dexamethasone Dose for Postoperative Nausea and Vomiting Prophylaxis in Obese Patients
compare the effectiveness of different doses of dexamethasone used for postoperative nausea and vomiting prophylaxis in obese patients and in normal weight patients.
- Trial name
- NCT04538820
- Testing
- Dexamethasone 4 mg IV-control, Dexamethasone 4 mg IV, Dexamethasone 8 mg IV
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Laparoscopic Surgery, Breathing Exercise
The Effect of Respiratory Exercise After Laparoscopic Surgery
Laparoscopic surgery (LS) enables the patient to experience the desired result with smaller incisions in the postoperative period, more aesthetically, stress-free and less painful.
- Trial name
- NCT05624346
- Testing
- Deep-Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Neurocognitive Disorders, Post Operative Delirium
Safe Brain Initiative, Operationalizing Precision Anaesthesia
Perioperatively, patients experience an unnecessarily high level of side effects associated with their treatment. These side effects include nausea, severe pain, anxiety, and stress.
- Conditions
- Neurocognitive Disorders, Post Operative Delirium, Pain, Nausea
- Trial name
- SBI (NCT05765162)
- Testing
- Patient reported ourcomes
- Where
- Denmark
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Post-operative Nausea and Vomiting
Mass-balance Study of [14C]-APD421 in Healthy Volunteers
Open-label, non-randomised, single dose study in 6 healthy male subjects to assess the mass balance recovery, metabolite profile, metabolite identification and pharmacokinetics of 14C-labelled APD421
- Trial name
- NCT02881840
- Testing
- 14C-APD421
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Acacia Pharma Ltd
Neuromuscular Block, Residual, Pain
Methylprednisolone vs Dexamethasone: Effects on Sugammadex Reversal, Pain, and Nausea in Adults
This randomized controlled trial aims to compare the effects of intravenous methylprednisolone and dexamethasone on the reversal time of rocuronium by sugammadex in adult patients undergoing elective septoplasty or rhinoplasty.
- Conditions
- Neuromuscular Block, Residual, Pain, Postoperative Nausea
- Trial name
- NCT07187037
- Testing
- Methylprednisolone (MP), Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting (PONV) in Surgical Patients
This study will compare two different drug regimens (oral dronabinol versus intravenous ondanseteron) for the prevention of post-operative nausea and vomiting (PONV).
- Trial name
- PONV (NCT00757822)
- Testing
- Dronabinol, Ondansetron
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Postoperative Nausea and Vomiting
Study of APD421 With and Without Ondansetron
Collection of pharmacokinetic and electrocardiograph data from healthy volunteers given APD421 +/- ondansetron
- Trial name
- NCT03583489
- Testing
- APD421, Ondansetron
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Acacia Pharma Ltd
Shoulder Injuries, Anesthesia
The Effects of Preloading Before Beach Chair Position
The main objective of this study is whether preloading before positioning would be effective for less hemodynamic instability. The study also analyzes that patients with preloading will decrease postoperative nausea and vomiting…
- Conditions
- Shoulder Injuries, Anesthesia, Hemodynamic Instability
- Trial name
- NCT04671537
- Testing
- Preloading with crystalloid fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postoperative Nausea and Vomiting
Prophylactic Antiemetic Efficacy of Palonosetron Versus Ondansetron for the Prophylaxis of Postoperative Nausea and Vomiting (PONV) in Women Over 60 Years Undergoing Laparoscopic Cholecystectomy
Despite the development of new drugs, nausea and vomiting after surgery (PONV) are still frequent. Antagonists 5HT3 receptors, such as ondansetron and palanosetron, are among the main characterized prophylactic agents in patients…
- Trial name
- NCT02541019
- Testing
- Ondansetron, Palonosetron
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital Federal de Bonsucesso
Postoperative Nausea and Vomiting
Post-operative Nausea Vomiting in Laparoscopic Cholecystectomy
To study the efficacy and side effects of ondansetron with dexamethasone in patients undergoing standard laparoscopic cholecystectomy (control group).
- Trial name
- PONV (NCT02803788)
- Testing
- ramosetron, ondansetron, dexamethasone
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
PONV, Propacetamol
The Opioid-sparing Effect and Reduced PONV Using Propacetamol in PCA Among Patients With High Risk of PONV
While Patient-controlled analgesia (PCA) has the advantage of effectively reducing the degree of postoperative pain, it can also affect the patient's outcome by several adverse effects such as postoperative nausea and vomiting…
- Trial name
- NCT02116257
- Testing
- Propacetamol, PCA regimen
- Where
- South Korea
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postoperative Nausea and Vomiting
Dexamethasone Versus Local Infiltration Technique for Tonsillectomy in Children
Tonsillectomy is one of the most frequent surgical operations performed in children [1-4]. It is usually associated with postoperative nausea and vomiting (PONV) with an incidence ranging from 23% to 73% [2].
- Trial name
- NCT02355678
- Testing
- dexamethasone, Local anesthetic infiltration, General anesthesia
- Where
- Lebanon
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Artificial Abortion, PONV(Post Operative Nausea and Vomiting)
The Time Point of Carboprost Methylate Administration and Perioperative Complications
Artificial abortion is the most widely used procedure in termination of first-trimester pregnancy. Cervical ripening before the operation guarantees operative convenience and decreases complications.
- Trial name
- NCT05834361
- Testing
- early vaginal administration of carboprost methylate, delayed vaginal administration of carboprost methylate
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital