Clinical trials: Post Operative Nausea and Vomiting
PONV
Granisetron vs Granisetron and Dexamethasone on the Reduction of Postoperative Nausea and Vomiting
Intrathecal morphine (ITM) has proven to be excellent in reducing postoperative pain. However, its use has commonly been associated with the occurrence of postoperative nausea and vomiting (PONV).
- Trial name
- NCT04570592
- Testing
- Granisetron 1 Mg/mL Intravenous Solution And Dexamethasone 4mg, Granisetron 1 Mg/mL Intravenous Solution
- Where
- Malaysia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Chemotherapy-Induced Nausea and Vomiting (CINV), Radiotherapy-induced Nausea and Vomiting (RINV)
A Study to Compare the Bioavailability of Ondansetron Following Nasal (NS003) and IV Administration in Healthy Adults
A Study to Compare the Bioavailability of Ondansetron Following Nasal (NS003) and IV Administration in Healthy Adults
- Conditions
- Chemotherapy-Induced Nausea and Vomiting (CINV), Radiotherapy-induced Nausea and Vomiting (RINV), Postoperative Nausea and Vomiting
- Trial name
- NCT07868861
- Testing
- NS003 Ondansetron HCl microspheres powder for nasal application, Ondansetron Solution for IV infusion 8mg
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nasus Pharma
Emergence Delirium in Pediatric Anesthesia, Pediatric Anesthesia
The Effect of Paedfusor TCI, Eleveld TCI, and Sevoflurane Anesthesia on Postoperative Awakening Agitation in Pediatric Patients
Emergence delirium is a common complication in pediatric patients undergoing general anesthesia. The aim of this study is to investigate the incidence of postoperative awakening delirium and agitation in pediatric patients aged…
- Conditions
- Emergence Delirium in Pediatric Anesthesia, Pediatric Anesthesia, Postoperative Agitations in Pediatric Patients, Postoperative Nausea and Vomiting (PONV)
- Trial name
- NCT07534956
- Testing
- propofol ( Paedfusor Model), propofol (Eleveld Model), Sevofluorane
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Postoperative Pain, Nausea and Vomiting, Postoperative
Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks
The goal of this clinical study is to improve upon the standard practice of utilizing nerve blocks to enhance the satisfaction of patients undergoing shoulder, or foot and ankle surgery regarding their quality of pain control…
- Conditions
- Postoperative Pain, Nausea and Vomiting, Postoperative, Dizziness, Constipation
- Trial name
- Dex-Dex PNB (NCT07099222)
- Testing
- Low, non-weight based dose of Dexamethasone and Dexmedetomidine in peripheral nerve blocks, Ropivacaine with low, non weight based Dexamethasone additive
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Postoperative Nausea and Vomiting
Antiemetic Efficacy and Safety of Dexamethasone in Obstetric Surgical Patients
This is a randomised controlled double blinded clinical trial to determine the antiemetic efficacy and safety of either 8 mg of dexamethasone or normal saline (placebo) given 1 hour before induction of either spinal or general…
- Trial name
- NCT01028547
- Testing
- dexamethasone, normal saline
- Where
- Uganda
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Makerere University
Treatment Complication
Acupuncture for Recovery and Postoperative Nausea and Vomiting After Middle Ear Surgeries
Modern surgery management needs increasing operating room turnover and more ambulatory surgery. In order to come over this challenge, the recovery needs to be optimized.
- Trial name
- NCT04748133
- Testing
- acupuncture needles
- Where
- Egypt
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Ileus, Postoperative Nausea
Assessing Gastric Motility and Distention in Postoperative Gastrointestinal Surgery Using Bedside Gastric Ultrasound: Predicting Risk of Aspiration Pneumonia, Ileus, Return of Bowel Function
Point-of-care gastric ultrasound will be used to measure stomach contents postoperative in patients who underwent colorectal surgery.
- Conditions
- Postoperative Ileus, Postoperative Nausea, Postoperative Complications, Postoperative Nausea and Vomiting
- Trial name
- NCT04747691
- Testing
- Bedside gastric ultrasound
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eric Schwenk
Postoperative Nausea and Vomiting
Use of Baxter Animated Retching Faces (BARF) Scale to Measure Nausea in Children Who Speak Spanish
Pediatric research in the management of nausea has been limited by the absence of a reliable method to quantify the intensity of this subjective symptom.
- Trial name
- NCT02007109
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Postoperative Nausea and Vomiting
Combination Antiemetic Regimen for Prevention of PONV in Breast Surgery Patients
The purpose of this study is to compare the efficacy of the use of oral aprepitant in combination with intravenous ondansetron and dexamethasone with the efficacy provided by the use of oral aprepitant and dexamethasone for…
- Trial name
- NCT00738621
- Testing
- Aprepitant, Dexamethasone, Ondansetron
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Scott and White Hospital & Clinic
Oxygen, Postoperative Nausea and Vomiting
The Effect of Oxygen Given to Patients in the Postoperative Period on Nausea and Vomiting
Carbon dioxide which is insufflated to inflate the abdominal area is absorbed from the peritoneal area and it increases endogenous catecholamines, which may consequently increase nausea and vomiting.
- Trial name
- NCT04597723
- Testing
- oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Postoperative Nausea and Vomiting
Impact of Timing of Midazolam Administration on Incidence of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV), defined as nausea and/or vomiting occurring within 24 hours after surgery, affects between 20% and 30% of patients, As many as 70% to 80% of patients at high risk may be affected.
- Trial name
- NCT05057767
- Testing
- Midazolam injection
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Benha University
Hemodynamics Instability, Pain After Surgery
Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients
The goal of this triple blinded randomized control trial is to compare the effect of magnesium sulphate on the hemodynamic response during pneumoperitoneum creation, along with its impact on postoperative pain, opioid…
- Conditions
- Hemodynamics Instability, Pain After Surgery, PONV in Laparoscopic Cholocystectomies
- Trial name
- NCT07079514
- Testing
- Magnesium
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Bispectral Index, Transcutaneous Carbon Dioxide
Compare the Side Effects and Difference Awake Level of Three TCI Propofol Formula in TVOR Patients
This study is to find the fewer side effects formula of anesthesia for TVOR patients, to compare the BIS level during emergence and to find the correlation between BIS and transcutaneous carbon dioxide concentration.
- Conditions
- Bispectral Index, Transcutaneous Carbon Dioxide, PONV, Blood Pressure
- Trial name
- NCT00760253
- Where
- Taiwan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Postoperative Nausea and Vomiting
Utility of Acupuncture in the Treatment of Postoperative Nausea and Vomiting in Ambulatory Surgery
To evaluate the Utility of Acupuncture in the Treatment of Postoperative Nausea and Vomiting (PONV) in Ambulatory Surgery.
- Trial name
- PUCTURE-NVPO (NCT01442012)
- Testing
- Ear seeds
- Where
- Spain
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Group G-6
Fasting
The Effects of Carbohydrate-electrolyte Solution on Metabolic Responses in Paediatric Patients
The aim of this study is to evaluate the effects of oral administration of carbohydrate-electrolyte-containing fluid, compared to standard clear fluid during preoperative fasting on metabolic responses, preoperative anxiety and…
- Trial name
- NCT05729100
- Testing
- Oral carbohydrate-electrolyte solution, Control
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Quality of Life, Breastfeeding
Quality of Recovery in Parturients Consumed Preoperative Carbohydrate Fluid for Elective Cesarean Delivery
The establishment of the Enhanced Recovery After Cesarean protocols resulted in to the production of specific care pathways with the aim of optimizing recovery after cesarean delivery (CD) and to reduce the costs to the health…
- Conditions
- Quality of Life, Breastfeeding, Postoperative Pain, Postoperative Nausea
- Trial name
- QoR-10 (NCT05841693)
- Testing
- Carbohydrate
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Surgery
The Effect of Oral Carbohydrate Inhalation Given to Patients Before Coronary Artery Bypass Graft Operation on Recovery
The aim of this study was to investigate the effect of oral carbohydrate solution given to patients before coronary artery bypass graft surgery on nausea-vomiting, hunger, thirst, physiologic parameters and recovery.
- Trial name
- NCT06788951
- Testing
- administration of oral carbohydrate solution to patients before coronary artery bypass graft surgery, giving flavored water to patients before coronary artery bypass graft surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Yasemin Bozkurt
Postoperative Nausea and Vomiting
Efficacy of PC6 Electroacupuncture in the Prevention of Nausea Vomiting in Caesarean Patient Under Spinal Anaesthesia
To determine the ability of electroacupuncture on PC6 versus sham acupuncture in reducing incidence of intraoperative and postoperative nausea vomiting in parturients who underwent Caesarean delivery under spinal anaesthesia
- Trial name
- NCT04801277
- Where
- Malaysia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Clinical Research Centre, Malaysia
PACU Length of Stay, Postoperative Nausea
Evaluation of Providing Coffee to Patients Postoperatively to Decrease Length of Stay in the PACU
The purpose of the study is to determine if providing coffee to patients who self-identify as coffee drinkers postoperatively will decrease the length of stay in the post-anesthesia care unit (PACU).
- Conditions
- PACU Length of Stay, Postoperative Nausea, Postoperative Vomiting, Patient Satisfaction
- Trial name
- NCT03712891
- Testing
- Coffee
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Bariatric Surgery Candidate, Perioperative Complication
Effects of Ondansetron, Metoclopramide and Granisetron on Perioperative Nausea and Vomiting in Patients Undergone Bariatric Surgery
Post-operative nausea and vomiting (PONV) is one of the leading causes of patient morbidity after laparoscopic bariatric surgeries.
- Conditions
- Bariatric Surgery Candidate, Perioperative Complication, Nausea, Vomiting, Postoperative
- Trial name
- PONV (NCT05087615)
- Testing
- Metoclopramide, Ondansetron, Metoclopramide and Ondanteron
- Where
- Iran
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences