Clinical trials: Post Operative Nausea and Vomiting (PONV)
Post Operative Nausea and Vomiting (PONV)
Efficacy of Adding Oral Amisulpride to Dual Prophylaxis for Postoperative Nausea and Vomiting in Patients at High Risk for Nausea and Vomiting Undergoing Gynecological Surgery
Amisulpride is a potent antagonist of dopamine D2 and D3 receptors, both implicated in the emetic response when activated. It is currently used intravenously for the prevention of chemotherapy-induced and postoperative nausea and…
- Trial name
- NCT06887621
- Testing
- Encapsulated amisulpride 50 mg (matched for color, weight, smell and size)
- Where
- Brazil
- Volunteers
- 276 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Post Operative Recovery, Post Operative Nausea and Vomiting (PONV)
A COMPARATIVE STUDY BETWEEN OPIOID-FREE GENERAL ANAESTHESIA AND OPIOID-BASED GENERAL ANAESTHESIA ON THE QUALITY OF RECOVERY IN PATIENTS UNDERGOING ELECTIVE LAPAROSCOPIC HYSTRECTOMY: A Randomized Trial
the intent of this study To compare the efficacy of opioid free general anaesthesia versus opioid based general anaesthesia to achieve enhanced recovery regarding post-operative pain and post-operative nausea and vomiting…
- Conditions
- Post Operative Recovery, Post Operative Nausea and Vomiting (PONV), Post Operative Analgesia
- Trial name
- NCT07739641
- Testing
- Fentanyl-Based Anesthesia, Opioid-Free Anaesthesia (Dexmedetomidine, Ketamine, and Lidocaine)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Tonsillitis, Post-operative Nausea and Vomiting (PONV)
Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
This is a prospective, randomized, controlled, non-inferiority study of patients undergoing tonsil surgeries at Boston Children's Hospital Waltham.
- Conditions
- Tonsillitis, Post-operative Nausea and Vomiting (PONV), Emergence Delirium, Opioid Analgesic Adverse Reaction
- Trial name
- NCT06326983
- Testing
- Dexmedetomidine, Acetaminophen, Ketorolac
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Boston Children's Hospital
Post Operative Pain Control, PONV
Effectiveness of Unilateral Transversus Abdominis Plane (TAP) Block vs Bilateral TAP Block in Patients Undergoing Laparoscopic Cholecystectomy.
In this study, patients undergoing laparoscopic cholecystectomy will be randomly divided into 2 groups after consent. Group A patients will be administered a one-sided (right unilateral) regional TAP block and group B patients…
- Trial name
- NCT07513012
- Testing
- Unilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine, Bilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- King Edward Medical University
APFEL RİSK SCORE, Post Operative Nausea and Vomiting (PONV)
Role of Apfel's Score in Predicting Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
The goal of this observational study is to assess the role of Apfel's score in predicting postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy in patients with symptomatic cholelithiasis.
- Trial name
- NCT06669325
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- National Medical College Birgunj
Post-operative Nausea and Vomiting (PONV)
Efficacy and Safety Study of Aprepitant Injection for Prevention of Post-operative Nausea and Vomiting
A randomized, double-blind, placebo-controlled, multi-center phase III study to compare the efficacy and safety of aprepitant injection and placebo in the prevention of post-operative nausea and vomiting (PONV).,
- Trial name
- NCT06543966
- Testing
- Aprepitant Injection
- Volunteers
- 486 people
- Sponsor
- CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
Artificial Abortion, PONV(Post Operative Nausea and Vomiting)
The Time Point of Carboprost Methylate Administration and Perioperative Complications
Artificial abortion is the most widely used procedure in termination of first-trimester pregnancy. Cervical ripening before the operation guarantees operative convenience and decreases complications.
- Trial name
- NCT05834361
- Testing
- early vaginal administration of carboprost methylate, delayed vaginal administration of carboprost methylate
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Post Operative Nausea and Vomiting (PONV), Adenotonsillectomy
Gabapentin Premedication and Adenotonsillectomy in Pediatric Patients
The frequent incidence of postoperative vomiting and severe pain in children undergoing adenotonsillectomy, may delay postoperative oral intake and increase the risk of dehydration.
- Trial name
- NCT02384187
- Testing
- Gabapentin as premedication
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Cairo University
Post-Operative Nausea and Vomiting (PONV)
Single Dose Safety Study for Compound to Treat Post-Operative Nausea and Vomiting (PONV)
The purpose of this study is to describe the safety and tolerability and pharmacokinetics of a single intravenous administration of the new, Sulfobutyl Ether-7-Beta-Cyclodextrin (Captisol™) based, formulation in Healthy Adult…
- Trial name
- NCT01290133
- Testing
- GW597599
- Where
- Australia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Accenture