Clinical trials: Post Operative Pain, completed
Pain, Postoperative, Opioid Use
Influence of Aging on Perioperative Methadone Dosing
Increasingly, elderly patients undergo anesthesia and surgery. Methadone is a great opioid for perioperative pain management, however, to date there are no pharmacokinetic or pharmacodynamic studies that asses a methadone dose…
- Conditions
- Pain, Postoperative, Opioid Use, Methadone Overdose of Undetermined Intent
- Trial name
- NCT04526236
- Testing
- Methadone Injectable Product
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Breast Cancer, Breast Cancer Female
PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery
In this double blinded randomized placebo-controlled trial, 160 subjects scheduled for breast surgery involving the axilla will be administered a multimodal pain regimen including acetaminophen, dexamethasone, celecoxib, and…
- Conditions
- Breast Cancer, Breast Cancer Female, Cancer of Breast
- Trial name
- NCT03084536
- Testing
- Bupivacaine, Gabapentin, Celecoxib
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Washington University School of Medicine
Colectomy
Evaluation of the Benefit of Non-opioid General Anaesthesia on Postoperative Pain in Laparoscopic Colonic Surgery
Evaluation of the benefit of non-opioid general anaesthesia on postoperative pain in laparoscopic colonic surgery
- Trial name
- AGORA (NCT05031234)
- Testing
- anaesthesia without opiates, anaesthesia with morphine
- Where
- France
- Volunteers
- 160 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Breast Neoplasms, Analgesia
Analgesic Efficacy of U/S Retrolaminar Block and Erector Spinae Plane Block in MRM
Modified radical mastectomy (MRM) is the most commonly performed surgical procedure in breast cancer patients and is usually associated with severe postoperative pain.
- Trial name
- NCT06322316
- Testing
- The Ultrasound-guided Retrolaminar Block Group, The Ultrasound-guided Erector Spinae Plane Block Group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Pain, Postoperative, Surgery
Pain Relief in Laparoscopic Surgery
Pain relief after laparoscopic surgery with the use of an altered gas.
- Trial name
- NCT03867552
- Testing
- Altered gas (86% CO2, 10% N2O, 4% O2), Standardized gas (100% CO2)
- Where
- Belgium
- Volunteers
- 74 people
- Sponsor
- Jessa Hospital
Symptomatic Periapical Periodontitis
Effect of Preoperative Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain
The aim of this prospective, randomized, placebo controlled study is to evaluate the effect of a single preoperative dose of amoxicillin/clavulanic acid combination on post-operative pain and swelling in adult patient with…
- Trial name
- NCT03033147
- Testing
- Amoxicillin/Clavulanate Potassium 875 mg-125 mg oral tablet
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Osteoarthritis,Knee
Efficacy of Multimodal Perioperative Analgesia With Periarticular Drug Injection in Total Knee Arthroplasty(TKA)
The purpose of this study is to compare different medication combinations used in a periarticular injection after total knee replacement surgery(TKR).
- Trial name
- NCT01042093
- Testing
- Ropivacaine, Toradol, Clonidine
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Towson Orthopaedic Associates
Pain Management, Analgesia
Comparison of a Comfort Scale and a Numerical Pain Scale on Opioid Consumption After Surgery
The objective is to show that the use of therapeutic communication tools, in this case a comfort scale, a low cost and simple to implement method, can reduce pain and therefore the consumption of opioids in the postoperative care…
- Trial name
- COMFORT (NCT05234216)
- Testing
- Informed consent, Surgery, Comfort scale
- Where
- 29 sites in France, Lebanon
- Volunteers
- 885 people
- Sponsor
- Rennes University Hospital
Postoperative Pain Relief
Transdermal Nicotine and Melatonin Patches for Postoperative Pain Relief
Sixty female non-smoker patients, aged 18-50 years and ASA I and II undergoing elective laparoscopic cholecystectomy under general anesthesia were included in this randomized controlled double-blind study.
- Trial name
- NCT02747628
- Testing
- transdermal therapeutic system- nicotine., transdermal therapeutic system- melatonin.
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Chronic Pain Following Surgical Procedure for Cancer
A Comparison of Gabapentin and Ketamine in Acute and Chronic Pain After Inguinal Hernia Repair
Patients were randomized into two groups: Group Gabapentine ( G group) received 600 mg of Gabapentin (two tablets) two hours prior to surgery and saline solution before induction of spinal anesthesia and group Ketamine ( K group)…
- Trial name
- NCT04700592
- Testing
- Gabapentin versus Ketamine
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Cheilitis, Angular, Postoperative Complications
Using Dexpanthenol Cream to Prevent Lip Corner Cracks in Children After Tonsil/Adenoid Surgery
Soreness and cracking at the corners of the mouth, a condition called angular cheilitis, can be an uncomfortable problem for children after they have surgery to remove their tonsils and adenoids.
- Conditions
- Cheilitis, Angular, Postoperative Complications, Adenotonsillar Hypertrophy
- Trial name
- PrevAC-PedAT (NCT07002632)
- Testing
- Dexpanthenol 5 % Topical Ointment
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Postoperative Pain
Abdominal Binder Study to Decrease Postoperative Pain
We conducted a controlled randomized trial examining the ability of the Mott abdominal Compression Binder to decrease postoperative pain in gynecologic abdominal laparotomy patients
- Trial name
- NCT01685593
- Testing
- abdominal binder, no binder
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Brooke Army Medical Center
Pain, Postoperative
Sublingual Sufentanil Tablet System (SSTS) Versus Intravenous Patient Controlled Analgesia After Back Surgery.
In this study, numeric rating scale (NRS) and side effects are measured after usage of a sublingual sufentanil tablet system (SSTS) in comparison to intravenous patient controlled analgesia (PCIA).
- Trial name
- NCT03036514
- Testing
- Sublingual sufentanil tablet system, Patient-controlled intravenous analgesia
- Where
- Belgium
- Volunteers
- 27 people
- Sponsor
- University Hospital, Antwerp
Opioid-use Disorder, Pain, Postoperative
BRIDGE Percutaneous Nerve Stimulation for Cesarean Delivery Pain Control
This is a randomized, placebo controlled and natural-history controlled trial to investigate the effectiveness of NSS-2 BRIDGE® for postpartum women with AND without opioid use disorder (OUD).
- Trial name
- NCT04365465
- Testing
- NSS-2 Bridge, Inactive NSS-2 Bridge, Active control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Post Operative Pain
Transversalis Fascia Plane Block Versus Erector Spinae Plane Block for Analgesia in Inguinal Hernia Repair
Uncontrolled postoperative pain after inguinal hernia repair increases the incidence of postoperative complications.
- Trial name
- NCT05565365
- Testing
- Transversalis fascia plane (TFP) block, Erector Spinae Plane (ESP) Block
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Assiut University
Pain, Postoperative, Cesarean Section
Bilateral Ultrasound-Guided Transversus Abdominis Plane (Tap) Block and Erector Spinal Plane (Esp) Block
Transversus Abdominis Plane Block (TAPB) is frequently used for the management of postoperative pain in patients undergoing cesarean section.
- Conditions
- Pain, Postoperative, Cesarean Section, Erector Spinae Plane Block, Transversus Abdominis Plane Block
- Trial name
- NCT05625009
- Testing
- Procedure/Surgery: Transversus Abdominis Plane Block (TAPB), Procedure/Surgery: Erector Spinae Plane Block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Chronic Postsurgical Pain
Clinical Prediction Model and External Validation of Chronic Postsurgical Pain in Elders
This study will collect perioperative pain-related data of elderly patients in multi-centers. Analyzing these collected data to find the high-risk factors of chronic postsurgical pain in elderly patients and to establish an…
- Trial name
- NCT05372406
- Testing
- • no intervention
- Where
- China
- Volunteers
- 7,770 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Pain, Trismus
Effect of CGF on Short Term Clinical Outcomes After Partially Impacted Mandibular Third Molar Surgery
The aim of this study was to evaluate the effectiveness of concentrated growth factor (CGF) on soft tissue healing and postoperative side effects following third molar surgery.
- Conditions
- Postoperative Pain, Trismus, Edema
- Trial name
- CGF (NCT03913884)
- Testing
- Concentrated growth factor, Non-Concentrated growth factor Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Rotator Cuff Tear
Post-Op Rotator Cuff Pain Study With Subacromial Bupivacaine Infusion
Subacromial pain catheters have been used with uncertain efficacy for many years after rotator cuff repair to aid in postoperative pain control.
- Trial name
- NCT01126593
- Testing
- 0.5% bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Orlando Health, Inc.
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