Clinical trials: Post Operative Pain, completed
Postoperative Pain
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-181)(COMPLETED)
The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.
- Trial name
- NCT00092300
- Testing
- MK0966, rofecoxib, Comparator: valdecoxib
- Volunteers
- 450 people
- Sponsor
- Merck Sharp & Dohme LLC
Amputation, Phantom Limb
Ambulatory Continuous Peripheral Nerve Blocks for Treatment of Post-Amputation Phantom Limb and Stump Pain
Research study to determine if putting local anesthetic-or numbing medication-through one or two tiny tube(s) placed next to the nerves that go to an amputated limb will decrease phantom limb and/or stump pain.
- Conditions
- Amputation, Phantom Limb, Stump Pain
- Trial name
- NCT00667264
- Testing
- perineural ropivacaine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of California, San Diego
Cholelithiasis, Cholecystectomy, Laparoscopic
Unilateral Laparoscopic TAP Block vs. Local Infiltration in Post-Cholecystectomy Analgesia
This study compared different methods of pain control after laparoscopic gallbladder removal. A total of 160 patients were randomly assigned to receive either a unilateral laparoscopic TAP block, local anesthetic infiltration, a…
- Conditions
- Cholelithiasis, Cholecystectomy, Laparoscopic, Pain, Postoperative, Anesthesia, Local
- Trial name
- TAP vs LAI (NCT07176299)
- Testing
- Unilateral laparoscopic TAP block (0.25% bupivacaine), Local anesthetic infiltration (0.25% bupivacaine), Combined TAP block and local anesthetic infiltration (0.25% bupivacaine)
- Where
- Poland
- Volunteers
- 160 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Pain
Drug Interactions Between Morphine and Orally or IV Administered Acetaminophen
Morphine is the opioid used to treat pain after surgery. Acetaminophen (called APAP) can reduce the amount of opioids needed for this. The problem is that morphine slows down digestion. That can delay pain relief from APAP pills.
- Trial name
- NCT02848729
- Testing
- Oral Acetaminophen, IV Acetaminophen, IV Morphine
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mallinckrodt
Pain, Postoperative, Hip Osteoarthritis
The Effect of Wrist Ankle Acupuncture on Post-Total Hip Arthroplasty Pain
Total hip arthroplasty is one of the most cost-effective orthopedic surgical procedures which can restore hip function and improve the patient's quality of life.
- Conditions
- Pain, Postoperative, Hip Osteoarthritis, Hip Fractures, Hip Injuries
- Trial name
- NCT06380439
- Testing
- wrist ankle acupuncture
- Where
- 3 sites in Indonesia
- Volunteers
- 32 people
- Sponsor
- Universitas Indonesia
Postoperative Pain After Ambulatory Surgery
Controlled-Release Oxycodone Versus Naproxen at Home After Ambulatory Surgery: A Randomized Controlled Trial
the primary objective of this study is to assess and compare the efficacy, safety and benefits of Controlled Release (CR) oxycodone/paracetamol with our current pain protocol (paracetamol/naproxen) in the treatment of acute…
- Trial name
- NCT02152592
- Testing
- PCM/Oxy1, PCM/Oxy2
- Where
- Netherlands
- Volunteers
- 105 people
- Sponsor
- Maastricht University Medical Center
Pain, Postoperative, Pain, Acute
Parecoxib in Total Knee Arthroplasty
Early mobilization and rehabilitation can be difficult after total knee arthroplasty (TKA) due to a high incidence of moderate to severe postoperative pain.
- Conditions
- Pain, Postoperative, Pain, Acute, Analgesia, Analgesic Nephropathy
- Trial name
- NCT05924412
- Testing
- Intravenous study drug, Intravenous saline solution
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- University of Chile
Pain, Postoperative, Anesthesia, Conduction
Effect of a Lateral Nerve of the Thigh Block on Postoperative Pain After Total Hip Replacement Surgery
The purpose of this study was to evaluate the analgesic efficacy of the nervus cutaneous femoral lateralis (NCFL) blockade on postoperative pain after total hip replacement surgery. The NCFL-block is a pure sensory block.
- Conditions
- Pain, Postoperative, Anesthesia, Conduction, Arthroplasty, Replacement, Hip
- Trial name
- NCT02289937
- Testing
- Ropivacaine, An ultrasound-guided Nervus cutaneous femoral lateralis blockade will be given postoperatively
- Volunteers
- 100 people
- Sponsor
- Daniel Hägi-Pedersen
Heal Wound, VAS Will be Used to Assess Pain Postoperative
Evaluation of the Effect of Different Biomaterials on Palatal Wound Healing.
All study subjects will sign written informal consent form before enrolment. They will be divided into four groups, 10 patients each: Group I: Palatal wound will be left to heal spontaneously, Group II: Palatal wound will be…
- Trial name
- NCT07072182
- Testing
- Palatal wound will be covered with Ora-aid patch, Palatal wound will be covered with Composite stent, Palatal wound will be covered with PRF
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fatma saad saad mahmoud elsherbini
Pain
Evaluation of Dexmedetomidine on Post-operative Narcotic Requirements and Pain Scores in Bariatric Patients
The purpose of the study is to determine whether a single bolus dose of dexmedetomidine administered during bariatric surgery has any effect on the amount of narcotic pain medications required by an individual after surgery.
- Trial name
- NCT02604940
- Testing
- Dexmedetomidine, Normal Saline
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- West Virginia University
Post Operative Pain, Analgesia
Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years
During general anesthesia, objective monitoring for analgesia is still lacking. The administration of opioids relies on the experience of the anesthesiologist.
- Conditions
- Post Operative Pain, Analgesia, Children, Only, Narcotic Use
- Trial name
- NCT05758090
- Testing
- NIPE monitor, Control
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Khon Kaen University
Opioid Use, Postoperative Pain
Comparing Intrathecal Morphine With Modified Thoracoabdominal Nerve Block Through Perichondral Approach in Major Abdominal Surgery
Abdominal surgery causes severe postoperative pain due to retraction of the abdominal wall and direct manipulation of visceral organs. It leads to delayed postoperative recovery, increased postoperative morbidity and mortality.
- Trial name
- NCT06346860
- Testing
- Regional Block Comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Marmara University
Diabetic Foot Ulcer, Lower Extremity Amputation
Comparison of Anesthetic Modalities on Hemodynamic Stability and Postoperative Pain in Diabetic Foot Patients Undergoing Minor Lower Extremity Amputation
Diabetic foot ulcer is the most common cause of non traumatic lower extremity amputations (LEA) associated with diabetes. Traditionally general and spinal anesthesia were the preferred modality of anesthesia.
- Trial name
- NCT02440282
- Volunteers
- 86 people
- Sponsor
- Yonsei University
Appendicitis Acute
Low vs Medium Pressure Pneumoperitoneum
The purpose of this study is to asses whether the pressure used for the pneumoperitoneum during laparoscopic surgery in children affects their postoperative pain levels.
- Trial name
- LoMePneu (NCT04949659)
- Testing
- Laparoscopic appendectomy
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- University Children's Hospital, Zurich
Cholecystitis, Pain
The Effect of Hyoscine-n-butylbromide on Nausea and Pain in Laparoscopic Cholecystectomy
The goal of this randomized double blind study is to compare the effects of hyoscine-n-butylbromide, and ondansetron on postoperative nausea-vomiting, and pain in patients who underwent laparoscopic cholecystectomy.The main…
- Conditions
- Cholecystitis, Pain, Nausea
- Trial name
- NCT06927817
- Testing
- hyoscine-n-butylbromide, ondansetron, • hyoscine-n-butylbromide • ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Postoperative Pain, Opioid Consumption
Lidocaine and Analgesia After Laparoscopic Cholecystectomy
The purpose of this study is to evaluate how effective is the intraoperative use of lidocaine to attenuate postoperative pain and opioids consumption after laparoscopic cholecystectomy
- Trial name
- NCT03620591
- Testing
- Lidocaine
- Where
- Greece
- Volunteers
- 98 people
- Sponsor
- Larissa University Hospital
Postoperative Pain
Comparison Between 3 Solutions of Bupivacaine of Adductor Canal Block for Anterior Cruciate Ligament Reconstruction
Adductor canal block (ACB) is a new technique gaining acceptance as an alternative analgesic method of femoral nerve block (FNB) following knee surgery. The advantage of ACB is its dominant sensory nerve block effect.
- Trial name
- NCT02805920
- Testing
- Bupivacaine
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Procare Riaya Hospital
Chronic Pain, Postoperative Pain
Epidemiological Study of Post-operative Chronic Pediatric Pain.
This study aims to estimate prevalence and determine risk factors for chronic pain at 3 months post-operative in pediatric surgery.
- Trial name
- PEDIACHRO (NCT04068350)
- Testing
- Pain questionnaire
- Volunteers
- 582 people
- Sponsor
- University Hospital, Bordeaux
Pain, Postoperative, Nerve Block
Application of Celiac Plexus Block in Postoperative Analgesia of Whipple Surgery
This subject intends to explore the value of intraoperative celiac plexus block in postoperative acute pain management and its promoting effect on patients' rapid recovery during Whipple surgery through a randomized controlled…
- Trial name
- NCT05205720
- Testing
- Celiac plexus block, Ropivacaine
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Knee Arthroplasty, Total, Peripheral Nerve Block
Postoperative Analgesia in Bilateral Knee Arthroplasties
To observationally compare the analgesic efficacy of LIA and S-FICB techniques and to record the pain scores of patients who underwent bilateral knee operations in the postoperative period.
- Conditions
- Knee Arthroplasty, Total, Peripheral Nerve Block, Pain, Postoperative
- Trial name
- NCT06357013
- Testing
- Bilateral Suprainguinal fascia iliaca compartment block, Local infiltration analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
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