Clinical trials: Post Operative Pain
Laparoscopic Inguinal Hernia Repair, Acute Post Operative Pain
Transversalis Fascia Plane Block for Laparoscopic Inguinal Hernia Repair
Transversalis Fascia Plane Block (TFPB) is a trunk block that blocks the T12- L2 spinal nerves by injection of local anesthetic between the transversus abdominis muscle and transversalis fascia on the lateral abdominal wall.
- Trial name
- TFPB (NCT06778629)
- Testing
- Transversalis Fascia Plane Block, Post Operative Pain Management, Port Site Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Post-operative Pain
Ultrasound Guided Erector Spinae Plane Block in Patients Undergoing VATS Lobectomy
This study will compare ESP block plus patient-controlled analgesia (PCA) to intercostal nerve block plus PCA as post-operative pain control for patients having video-assisted thorascopic surgeries.
- Trial name
- NCT03176667
- Testing
- Ultrasound guided erector spinae plane block, Intercostal block
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University
Labor Pain, Anxiety
The Effect of Musıc on Labor Paın, Anxıety and Breastfeedıng Success
The aim of this study is to examine the effects of music played to primiparous women who had a cesarean section on pain, state anxiety and breastfeeding success.
- Conditions
- Labor Pain, Anxiety, Breast Feeding, Post Operative Pain
- Trial name
- NCT06621238
- Testing
- Music
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Analgesia, Pain Management
Ultrasound-Guided Recto-Intercostal Fascial Plane Block in Laparoscopic Cholecystectomy
The aim of the study is to reduce postoperative pain by performing rectointercostal block in L/S cholecystectomy surgeries. Main goal is to provide well managed post-operative analgesia.
- Conditions
- Analgesia, Pain Management, Pain, Acute Post-Operative
- Trial name
- NCT07745972
- Testing
- Rectointercostal facial plane block using bupivacaine 0.25%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Pain Management, TKA
Photobiomodulation Therapy for Pain Control in Post-Operative Total Knee Arthroplasty Patients: A Pilot Study
A pilot study to assess the efficacy and feasibility of PBMT for pain control in patients undergoing a TKA and are discharged the same day from an ambulatory surgery center.
- Conditions
- Pain Management, TKA, Post Operative Analgesia, Low Level Laser Therapy
- Trial name
- NCT07750912
- Testing
- LightForce XLI
- Volunteers
- 15 people
- Sponsor
- Mohammad Burney, MD
Post Operative Pain, Analgesia
Evaluation of Postoperative Pain Control in Ear Surgery
Middle ear surgery is the most popular procedure in ear, nose and throat surgery. Increased sympathetic stimulation after surgery can activate the sympathetic system, causing hypertension and increased heart rate.
- Trial name
- NCT06869967
- Testing
- Auricularis Magnus Nerve Block, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Kocaeli University
Macromastia, Post-operative Pain
Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty
The main question this randomized control trial aims to answer is: Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who undergo bilateral reduction…
- Trial name
- NCT05898087
- Testing
- Marcaine 0.25 % Injectable Solution, Saline
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Post Operative Pain
Assessment of Post-Operative Pain After Using Cryotherapy and Dexamethasone
Evaluation and comparing the effect of cryotherapy and dexamethasone on inflammatory mediators and post-operative pain in symptomatic irreversible pulpitis with acute apical periodontitis.
- Trial name
- NCT07738302
- Testing
- cold NaOCl , dexamethasone, NaOCl, dexamethasone, cold NaOCl and cold saline
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Acute Pain, Post Operative Analgesia
Analgesic Efficacy of Combined PECS II and PIP Block Versus Thoracic Paravertebral Block Post-Mastectomy
Postoperative pain management is crucial for patients undergoing mastectomy for breast cancer. Regional analgesia techniques, such as the Thoracic Paravertebral Block (TPVB), are commonly used to reduce pain and opioid…
- Conditions
- Acute Pain, Post Operative Analgesia, Post Operative Pain, Acute, Breast Cancer
- Trial name
- PECS-TPVB (NCT07738770)
- Testing
- Combined PECS II and Superficial PIP Block, Thoracic paravertebral block (TPVB)
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Dharmais National Cancer Center Hospital
Vitreoretinal Surgery, Ocular Inflammation
Dextenza in the Post-op Management of Vitreoretinal Surgeries
This study will assess the control of inflammation at days 1, 7, 14, and 21 days following the vitreoretinal surgical procedure analyzing two randomized study arms: Intracanalicular dexamethasone insert group or topical steroid…
- Conditions
- Vitreoretinal Surgery, Ocular Inflammation, Post-operative Pain, Post-Operative Inflammation
- Trial name
- NCT04371445
- Testing
- Dexamethasone Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
Anxiety, Pain
Effectiveness of Virtual Reality in Reducing Anxiety and Pain During the First Postoperative Orthopedic Dressing Change in Pediatric Patients
The goal of this randomized clinical trial is to learn whether immersive virtual reality can reduce anxiety and pain in children and adolescents undergoing postoperative orthopedic dressing changes.
- Conditions
- Anxiety, Pain, Post Operative
- Trial name
- VR OrthoPed (NCT07729020)
- Testing
- Immersive Virtual Reality Distraction, Standard Postoperative Dressing Care
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Gianluca Catania
Transversus Thoracic Plane Block, Cardiac Surgery
Transversus Thoracic Plane Block for Perioperative Analgesia in Cardiac Surgery
The goal of this clinical trial is to learn if perioperative Transversus Thoracic Plane Block (TTPB) decrease perioperative pain after cardiac surgery. The main questions it aims to answer are: 1.
- Conditions
- Transversus Thoracic Plane Block, Cardiac Surgery, Post Operative Pain
- Trial name
- NCT06546722
- Testing
- Transversus Thoracic Plane Block
- Where
- Lebanon
- Volunteers
- 150 people
- Sponsor
- Saint-Joseph University
Video Assisted Thoracoscopic Surgery, Lobectomy
SERRATHOR TRIAL : Interest of the Novel Serratus Plane Block in Post Operative Analgesia After Video-Assisted Thoracoscopic Lobectomy
Pain after thoracic surgery remains a challenge for anesthetists. Although VATS for lobectomy is associated with fewer complications compared to thoracotomy, pain after VATS needs to be treated with opioids.
- Conditions
- Video Assisted Thoracoscopic Surgery, Lobectomy, Pain Post Operative, Regional Anesthesia
- Trial name
- SERRATHOR (NCT03867695)
- Testing
- Ropivacaine, sterile saline
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Post-operative Pain, Opioid Use
QL vs LAI for Palatoplasty
This study will consist of patients ages 6-18 who are undergoing a surgery on the hard or soft palate of the mouth (palatoplasty), with removal of bone from the front of the hip (anterior iliac bone graft harvesting).
- Conditions
- Post-operative Pain, Opioid Use, Cleft Palate
- Trial name
- NCT06420336
- Testing
- Quadratus lumborum block, Local anesthetic infiltration
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Medical University of South Carolina
Post Operative Pain
Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy
The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two extended local anesthesia strategies currently approved by…
- Trial name
- NCT06349772
- Testing
- Zynrelef, Exparel
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Post Operative Pain, Chronic Pain
Performance and Safety of the ANTALGEEK® Thess Monitoring Medical Device in the Outpatient Management of Acute Pain and Postoperative Recovery
Acute postoperative pain (APOP) is a major public health problem, affecting nearly 10 million patients in France each year. Effective analgesic therapy in the first postoperative week is a key factor in reducing early…
- Trial name
- TRACE (NCT07680998)
- Testing
- Post-operative follow-up using the Thess Telemonitoring device in conjunction with the ANTALGEEK® protocol
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Acute Post Operative Pain
Acute Postoperative Pain in Outpatient UKA
This study determined or observe the acute postoperative between outpatient UKA and inpatient UKA. We observe the acute post op. at at 0,1, and 2. The acute post op pain compeared between two groups.
- Trial name
- Outpatient UKA (NCT07686523)
- Where
- 2 sites in Thailand
- Volunteers
- 244 people
- Sponsor
- Thammasat University
Cardiac Surgery, Post Operative Pain, Acute
Serratus Posterior Superior Plane Block for Postoperative Pain in Cardiac Surgery
The aim of this study is to investigate the efficacy of bilateral serratus posterior superior intercostal plane (SPSIP) block on postoperative acute pain and opioid consumption in patients undergoing on-pump open-heart surgery.
- Trial name
- NCT07164677
- Testing
- Bilateral ultrasound guided Serratus Posterior Superior Plane Block, IV morphine patient-controlled analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ondokuz Mayıs University
Post Operative Pain, Acute
A Study of Combogesic® 325 in Adolescent Patients With Moderate to Severe Postoperative Pain Associated With Orthopedic Surgery
Combogesic® 325 contains a combination of ibuprofen and acetaminophen. The purpose of this study is to compare the pain relief effects of Combogesic® 325mg and acetaminophen and to evaluate the safety of Combogesic® 325mg in…
- Trial name
- NCT07225140
- Testing
- Combogesic® tablets, Acetaminophen 500mg
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- AFT Pharmaceuticals, Ltd.
Post Operative Pain, Acute, Laparoscopic Appendectomy
Intraoperative Intravenous Lidocaine for Pain After Laparoscopic Appendectomy
This randomized, double-blind, placebo-controlled clinical trial evaluated whether intraoperative intravenous lidocaine infusion improves postoperative analgesia and recovery in patients undergoing laparoscopic appendectomy.
- Trial name
- LIDO-APP (NCT07678385)
- Testing
- Lidocaine (drug)
- Where
- Venezuela
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Caracas