Clinical trials: Post Operative Pain, completed
Postoperative Pain
Postoperative Pain and Polyamines-poor Diet (DOLAMINE)
Animal studies have shown that the level of pain sensitivity is highly dependent on the amount of polyamines in food. This fundamental observation of a nutritional approach to pain led the authors to develop diets completely…
- Trial name
- DOLAMINE (NCT02592460)
- Testing
- poor-polyamines diet, high polyamines diet
- Where
- France
- Volunteers
- 542 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Blepharoptosis
Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid
Conjunctival Mullerectomy is a well known procedure used to correct upper lid ptosis via a posterior approach. Patients who undergo this procedure are often given local anesthesia to alleviate intraoperative and postoperative…
- Trial name
- NCT01350024
- Testing
- Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine, Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Miami
Pain, Postoperative
Study of Buprenorphine Sublingual Spray Versus Standard of Care Narcotic Therapy for the Treatment of Post-Operative Pain
This study will evaluate the safety and tolerability based on the incidence of adverse experiences of buprenorphine sublingual spray (0.5 milligrams [mg] three times daily [TID]) compared with standard post-operative narcotic…
- Trial name
- NCT03254459
- Testing
- Buprenorphine Sublingual Spray, Morphine, Oxycodone Hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- INSYS Therapeutics Inc
Post-surgical Pain
Hydromorphone Hydrochloride Epidural Preemptive Analgesia for Postoperative Pain After Cesarean Section
Acute pain often occurs after cesarean section, which can lead to stress and inflammatory response in the body, which will not only affect the postpartum recovery speed of the puerpera, but also inhibit the secretion of prolactin…
- Trial name
- HHEPA (NCT06823180)
- Testing
- Hydromorphone hydrochloride low dose, Hydromorphone hydrochloride high dose, 0.9% sodium chloride
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Liquan Liang
Anterior Cruciate Ligament Reconstruction
Study of Pain Management Techniques Following Anterior Cruciate Ligament Repair Surgery
Patients scheduled to undergo knee arthroscopy with anterior cruciate ligament repair with graft from the ipsilateral hamstrings and gracilis will be randomized to one of three groups.
- Trial name
- NCT01868282
- Testing
- Hamstrings block, Obturator block, Control group
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pain
Injectable Diclofenac for the Prevention of Post-operative Dental Pain
This is a prospective, randomised, double-blind, placebo-controlled, parallel group study in approximately 75 patients undergoing surgical removal of an impacted lower third molar.
- Trial name
- DP4 (NCT01706588)
- Testing
- Diclofenac sodium
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- IBSA Institut Biochimique SA
Post-operative Pain
Electronic Visual Analogue Scale in Acute Postoperative Pain
When assessing acute post-operative pain, the validity, reproducibility and reliability of Visual Analogue Scale (VAS) and verbal Numerical Rating Scale (NRS) have been investigated extensively.
- Trial name
- NCT01878903
- Testing
- Electronic VAS
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Cheung Chi Wai
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Pain, Postoperative
Rhomboid Intercostal Block Compared With Thoracic Paravertebral Block in Breast Cancer Surgeries
Postoperative pain is a significant problem following breast surgery . If not treated in time, it may lead to delayed wound healing, respiratory depression, hemodynamic disorders, anxiety,other complications, and finally lead to…
- Trial name
- NCT06781346
- Testing
- Rhomboid Intercostal Block, Thoracic Paravertebral Block
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Hypothermia
Study to Determine the Effects of Pre-warming on OR Patient Temperatures and Surgical Outcomes
The application of active warming to patients whether awake or under general anesthesia has been proven safe in numerous studies and it is common practice to use warmers.
- Trial name
- NCT02177903
- Testing
- Bair Paws Patient Adjustable Warming System
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Solventum US LLC
Postoperative Pain, Post Operative Analgesia
Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy
Dexamethasone has been recognized as an antiemetic agent after surgeries, and the combination of dexamethasone and tramadol remained stable in solution up to 5 days. In addition, i.v.
- Conditions
- Postoperative Pain, Post Operative Analgesia, Patient-Controlled Analgesia, Abdominal Surgeries
- Trial name
- DTMPCA (NCT00564603)
- Testing
- Dexamethasone Sodium Phosphate Injection, 0.9% Saline
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Nanjing Medical University
Pain, Postoperative
Pericapsular Nerve Group Block vs Supra Inguinal Fascia Iliaca Compartment Block
This study aims to assess the efficacy of PENG block performed with LFCN block in controlling postoperative pain and promoting motor function recovery and to compare its effectiveness with S-FICB.
- Trial name
- NCT06321718
- Testing
- PENG + LFCN block versus S-FICB
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Assiut University
Pain, Postoperative
Randomized Study Comparing the Use of Epidural Analgesia to Intravenous Narcotics for Laparoscopic Colorectal Resection.
Laparoscopic colorectal surgery (LCS) has gained wide acceptance in the treatment of various pathology from diverticular disease to colon cancer.
- Trial name
- NCT02086123
- Testing
- Epidural Analgesia, Parenteral Analgesia (Intravenous)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of California, Irvine
Postoperative Pain
REGIONAL ANALGESIA TECHNIQUES FOR EFFECTIVE RECOVERY TO CORONARY ARTERY BYPASS SURGERIES: A RETROSPECTİVE STUDY IN A SINGLE CENTER EXPERIENCE
Background Pain after cardiac surgery is both multifocal and multifactorial. Sternotomy, sternal retraction, internal mammary dissection, posterior rib dislocation or fracture, possible brachial plexus injury, and mediastinal and…
- Trial name
- NCT05282303
- Testing
- CABG operation
- Where
- Turkey (Türkiye)
- Volunteers
- 221 people
- Sponsor
- V.K.V. American Hospital, Istanbul
Pain, Postoperative
Spinal Morphine for Postoperative Analgesia in Urology
The study was performed in urology patients elicited for open prostatectomy or open nephrectomy. Comparison of analgesic effect between group (M) with spinal morphine before general anaesthesia and group without this intervention…
- Trial name
- NCT03675646
- Testing
- Morphine
- Where
- Czechia
- Volunteers
- 98 people
- Sponsor
- Charles University, Czech Republic
Postoperative Pain, Satisfaction with Care
Thoracic Spinal Versus Thoracic Epidural Anesthesia for Patients with Chronic Obstructive Pulmonary Disease Undergoing Supine Percutaneous Nephrolithotomy for Management of Renal Stones.
Owing to the elevated risk of perioperative comorbidities, chronic obstructive and restrictive pulmonary disorders can be a challenging task for the anesthetist.
- Trial name
- NCT06663488
- Testing
- Thoracic epidural anesthesia, Thoracic spinal anesthesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Postoperative Analgesia, Laparoscopic Hysterectomy
Preemptive Analgesia in Laparoscopic Hysterectomy
The aim of this study is to evaluate the effects of ibuprofen and paracetamol administered for pre-emptive analgesia to patients undergoing laparoscopic hysterectomy on pain scores during the first 24 hours postoperatively, the…
- Trial name
- NCT07401927
- Testing
- Ibuprofen, Parasetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Giresun University
Osteoarthritis Knees Both
Reparel Knee Sleeve vs. TED Hose for Post-op Swelling, Pain and Range of Motion After Total Knee Replacement
This prospective study will evaluate pain, swelling, ROM as well as narcotic use in post-operative total knee arthroplasty patients using novel Non-Compressive Bioactive Garment (NCBG) versus current standard of care gradient…
- Trial name
- NCT04751942
- Testing
- Non-compressive Bioactive Garment, thrombo-embolic deterrent
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Hysterectomy, Myoma
Morphine vs. Oxycodone for Postoperative Pain Management
The purpose of this study is to determine whether oxycodone provides better analgesia compared to morphine after laparoscopic hysterectomy or myomectomy.
- Conditions
- Hysterectomy, Myoma, Postoperative Pain, Opioids
- Trial name
- NCT00528177
- Testing
- Morphine and oxycodone
- Where
- Norway
- Volunteers
- 90 people
- Sponsor
- Ullevaal University Hospital
Dysphagia, Pain
Dexamethasone in Reducing Oral Pain and Dry Mouth After Surgery in Patients With Oropharyngeal Cancer
This randomized pilot clinical trial studies dexamethasone in reducing oral pain and dry mouth after surgery in patients with oropharyngeal cancer. Dexamethasone may help lower pain and dry mouth caused by surgery.
- Conditions
- Dysphagia, Pain, Stage I Oropharyngeal Squamous Cell Carcinoma, Stage II Oropharyngeal Squamous Cell Carcinoma
- Trial name
- NCT01748942
- Testing
- Dexamethasone, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- OHSU Knight Cancer Institute
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