Clinical trials: Post Operative Pain, completed
Impacted Mandibular Third Molar, Postoperative Pain
Effect of Platelet-Rich Fibrin on Postoperative Pain, Trismus, and Edema After Mandibular Third Molar Surgery
Impacted mandibular third molars are among the most commonly encountered conditions in oral and maxillofacial surgery. Surgical removal of these teeth is frequently associated with postoperative complications such as pain, facial…
- Conditions
- Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Edema Face
- Trial name
- PRF-M3M (NCT07672951)
- Testing
- Platelet-rich fibrin (PRF), Sterile Absorbable Gelatin Sponge
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- PAEC General Hospital, Islamabad
Postoperative Pain, Inguinal Hernia
The Effect of Erector Spinae Plane Block on Quality of Recovery and Postoperative Analgesia After Inguinal Hernia Repair
Inguinal hernia repair (IHR) is one of the most commonly performed operations in general surgery practice. Different pharmacological approaches and interfascial plane blocks are used to control postoperative pain.
- Conditions
- Postoperative Pain, Inguinal Hernia, Acute Pain
- Trial name
- NCT04300153
- Testing
- ESP Block, Global Quality of Recovery-15 score, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Başak Altıparmak
Postsurgical Pain
Efficacy and Safety Study of Ketorolac / Pitofenone / Fenpiverinium for the Treatment of Patients With Pain After Surgical Abdominal and Pelvic Operations
Neospastil (ketorolac tromethamine / pitofenone hydrochloride / fenpiverinium bromide fixed-dose combination) in a form of solution for injections and film-coated tablets has been studied as a treatment for pain after surgical…
- Trial name
- NCT05607641
- Testing
- Ketorolac tromethamine, solution for injection then Neospastil, film-coated tablets, Ketorolac tromethamine, solution for injection then Ketorolac tromethamine, coated tablets, Neospastil, solution for injection then Neospastil, film-coated tablets
- Where
- 14 sites in Ukraine
- Volunteers
- 424 people
- Sponsor
- Darnitsa Pharmaceutical Company
Pain, Postoperative, Arthroplasty, Replacement, Knee
Intrathecal Morphine in Knee Arthroplasty
This study is designed to explore the efficacy lower doses of intra-spinal morphine for pain relief and side effect profiles of same in the setting of Total Knee Replacement.We hypothesized that a dose greater than that used in…
- Trial name
- NCT00695045
- Testing
- intra thecal morphine
- Volunteers
- 60 people
- Sponsor
- University College Hospital Galway
Total Knee Anthroplasty, Genicular Nerves Block
Efficacy of Genicular Block on Total Knee Arthroplasty Surgery
This prospective, randomized, double-blind, placebo-controlled trial evaluated the analgesic efficacy of preoperative ultrasound-guided genicular nerve block (GNB) in patients undergoing total knee arthroplasty.
- Trial name
- NCT06942702
- Testing
- Genicular blocks (bupivakain), Paracetamol (acetaminophen)+diclofenac, Patient Control Analgesia (PCA) Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Mersin University
Pain, Postoperative
Magnesium Sulfate Improves Postoperative Analgesia in Laparoscopic Gynecologic Surgeries
Magnesium sulfate has been reported to improve postoperative pain, but evidence is still controversial. Some studies demonstrated benefits while others concluded that there is no efficacy.
- Trial name
- Magnesium (NCT02508857)
- Testing
- Ketorolac, Magnesium, Saline solution
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Pain, Postoperative, Postoperative Nausea and Vomiting
Dexamethasone for Post-cesarean Delivery Pain
The purpose of this study is to compare post-cesarean section consumption of pain medication between two groups of patients undergoing scheduled cesarean section at term gestation who receive a single-dose of intraoperative…
- Trial name
- NCT01812057
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Duke University
Post Operative Pain, Inflammation
Postoperative Pain Assessment After Canal Preparation by Different NiTi File Systems
The participants were divided into two groups : group one ( Trunatomy file group)(n=10) was mechanically prepared the canals by Trunatomy file and group two ( Edgeendo x7 file group) ( n=10) was prepared the canals by Edgeendo x7…
- Trial name
- NCT06286995
- Testing
- Chemomechanical preparation for root canals
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Fractured Neck of Femur, Postoperative Pain
Postoperative Analgesia for Fractured Neck of Femur With Periarticular Infiltration of Local Anaesthetic
The purpose of this study is to determine that periarticular levobupivacaine infiltration after surgical fixation of fractured neck of femur will improve the early postoperative pain sensation.
- Trial name
- NCT02057601
- Testing
- Levobupivacaine infiltration group
- Where
- Ireland
- Volunteers
- 37 people
- Sponsor
- Cork University Hospital
Lower Extremity Surgery, Upper Extremity Surgery
Perineural Catheter Insertion Distance for Continuous Peripheral Nerve Blocks
This is a research study to determine if the effects of continuous peripheral nerve blocks are influenced by the distance of insertion past the needle tip of the perineural catheter.
- Conditions
- Lower Extremity Surgery, Upper Extremity Surgery, Post-operative Pain
- Trial name
- NCT00997867
- Testing
- Sciatic catheter left 0-1cm past needle tip vs. 5-6cm past needle tip
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of California, San Diego
Arrythmia, Pain, Acute
Stellate Ganglion Block in Control of Arrhythmia in Laparoscopic Cholecystectomy
During Laparoscopic cholecystectomy, carbon dioxide (CO2) pneumoperitoneal laparoscopic surgery, CO2-pneumoperitoneum activates the sympathoadrenomedullary system to increase the release of catecholamines such as epinephrine (E)…
- Trial name
- NCT04837495
- Testing
- right stellate ganglion block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Postoperative Pain, Video-assisted Thoracoscopic Surgery
ESP Block, CNP and QoL After VATS
The Erector Spinae Plane Block (ESPB) is an adequate alternative for pain management after video-assisted thoracoscopy surgery (VATS).
- Trial name
- NCT04737902
- Testing
- Erector spinae plane block
- Where
- Colombia
- Volunteers
- 42 people
- Sponsor
- Hospital Universitario San Ignacio
Postoperative Pain, vNOTES
Does Intraperitoneal Washout Further Reduce Pain After Low-Pressure vNOTES Hysterectomy?
The evolution of minimally invasive gynecology has transitioned from traditional laparotomy to laparoscopy, and most recently, to vNOTES (Vaginal Natural Orifice Transluminal Endoscopic Surgery).
- Trial name
- Low-Pressure (NCT07467577)
- Testing
- warm saline
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Post Operative Pain, Acute
Comparison Between the Analgesic Effect of Fascia Transversalis Block vs Caudal Block
Despite the growing interest in interfascial blocks and their successful use in pediatric surgeries, no previous randomized clinical trials have directly compared the analgesic efficacy, opioid-sparing effect, and safety profile…
- Trial name
- NCT07235475
- Testing
- Caudal Block Anesthesia, Fascia Transversalis Block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Postoperative;Pain Management
Effects of Serratus Posterior Superior Intercostal Plane Block and Pectoralis Nerve Block in Coronary Artery Surgery
Postoperative analgesia is a critical risk factor for the development of pulmonary and cardiovascular complications in all types of chest surgery, particularly coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT06242431
- Testing
- Group serratus posterior superior intercostal plane block (SPSIPB), Group pectoralis nerve block (PECS-II)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Hitit University
Postsurgical Pain
Study Evaluating the Safety, Efficacy and Pharmacokinetics of CA-008 (Vocacapsaicin)
In the pilot (Part A) of this study, multiple doses of CA-008 (vocacapsaicin) were evaluated for safety, tolerability, and PK. Doses were then selected for the expanded part (Part B) of the study, where CA-008 was compared to…
- Trial name
- NCT04203537
- Testing
- CA-008
- Where
- 4 sites in United States
- Volunteers
- 193 people
- Sponsor
- Concentric Analgesics
Cesarean Section, Postoperative Pain
Ketamine for Analgesia After Cesarean Section
In this prospective randomized trial, investigators compared the analgesic effect of subanesthetic dose of ketamine versus placebo in parturients undergoing cesarean section under spinal anesthesia.
- Trial name
- NCT04545801
- Testing
- 0.25 mg/kg of Ketamine, 20ml of normal saline solution
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- Mongi Slim Hospital
Pain, Postoperative, Opioid Consumption, Postoperative
Intravenous Lidocaine and Acute Rehabilitation
Background: Intravenous infusion of lidocaine may decrease postoperative pain and speed return of bowel function. The investigators therefore tested the hypothesis that including perioperative lidocaine infusion improves recovery…
- Conditions
- Pain, Postoperative, Opioid Consumption, Postoperative, Postoperative Fatigue
- Trial name
- NCT00330941
- Testing
- lidocaine
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Pain Postoperative
Foraminal Enlargement and Postoperative Pain.
The purpose of this study is to determine whether enlarging the apical foramen causes postoperative pain in teeth with necrotic pulp and apical periodontitis.
- Trial name
- NCT02770053
- Testing
- Foraminal enlargement
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Isparta Military Hospital
Burns
Amniotic Membrane for Donor Site Healing
The purpose of this study is to compare the effectiveness of applying amniotic membrane dressings compared to gentamicin and xeroform dressings to donor sites for skin grafts.
- Trial name
- NCT02947737
- Testing
- Amniotic membrane dressing, Gentamicin and xeroform dressing
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Emory University
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