Clinical trials: Post Operative Wound Infection
Post-operative Infections
Reduction in IV Associated Contamination
The purpose of this study is to investigate whether implementing a novel syringe and IV stopcock cap system impregnated with alcohol will reduce IV catheter bacterial contamination and infections in patients.
- Trial name
- NCT01426217
- Testing
- Passive Bundle PSI (Problem Solving Innovations) Medical HubScrub, PSI Medical DocIt
- Where
- United States
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Surgical Site Infection, Wound Complication
VAC Dressings for Colorectal Resections
Surgical Site Infections (SSIs) and wound complications are common occurrences following colorectal resection surgery. Incisional Negative Pressure Wound Therapy (iNPWT) has developing evidence for improving wound complication…
- Conditions
- Surgical Site Infection, Wound Complication, Wound Dehiscence, Seroma
- Trial name
- VACCRR (NCT02967627)
- Testing
- Incisional Negative Pressure Wound Therapy (iNPWT), Sterile Gauze Dressing
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Abdominal Wall Wound
Impact of Timing of Wound Dressing Removal After Cesarean Section
The purpose of this study is to assess wound healing at 24 vs 48 hours post cesarean delivery with a modified 1-day ASEPSIS score.
- Trial name
- NCT02445729
- Testing
- Dressing removal at 24 hours, Dressing removal at 48 hours
- Where
- 3 sites in United States, Turkey (Türkiye)
- Volunteers
- 869 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Surgical Site Infection
Local Subcutaneous Gentamicin for Prevention of Surgical Site Infection After Elective Cesarean Section
The goal of this clinical trial is to evaluate whether local subcutaneous administration of gentamicin reduces the incidence of surgical site infection (SSI) following elective cesarean section.
- Trial name
- NCT07311395
- Testing
- Gentamicin, Standard antibiotic prophylaxis
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Surgical Wound Infection, Cesarean Section
Preventing Adverse Incisional Outcomes at Cesarean Multicenter Trial
The Prophylactic Negative Pressure Wound Therapy in Obese Women at Cesarean Trial is a large pragmatic multi-center randomized clinical trial designed to evaluate the effectiveness, safety and cost-effectiveness of prophylactic…
- Trial name
- Prevena-C (NCT03009110)
- Testing
- Prophylactic NPWT, Standard Dressing
- Where
- 6 sites in United States
- Volunteers
- 1,624 people, healthy volunteers welcome
- Sponsor
- Indiana University
Surgical Site Infection, Gynecologic Cancer
Effectiveness of Wound Drains for the Prevention Of Surgical sITe infectION
The aim of the present randomized trial is to assess the efficacy of wound drains in terms of reducing the rates of surgical site infection in obese patients with gynecological cancer.
- Conditions
- Surgical Site Infection, Gynecologic Cancer, Wound Drain
- Trial name
- POSITION (NCT05179122)
- Testing
- Surgical drain
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Bacterial Infection, Anti-infective Agents
Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction
Antibiotics are used routinely in postoperative tissue expander based breast reconstruction (TE) and autologous flap (AF) breast reconstruction procedures.
- Conditions
- Bacterial Infection, Anti-infective Agents, Breast Implantation
- Trial name
- NCT01244698
- Testing
- Cefadroxil discontinued early, Cefadroxil until drain removal
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Surgical Scrubbing, Surgical Site Infection
Surgical Hand Scrubbing Methods and the Duration of Scrubbing Time
Surgical hand scrubbing is the removal of transient flora and reduction of permanent flora as much as possible before any sterile gloves are worn before any surgical intervention.
- Trial name
- NCT04579705
- Testing
- Using a brush
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Prevention of Surgical Site Infections
Tumescent Antibiotic Delivery Pharmacokinetics
Tumescent Antibiotic Delivery (TAD) is a technique for improving the prevention of surgical site infections (SSI). TAD involves the subcutaneous infiltration of tumescent local anesthesia (TLA) containing water soluble…
- Trial name
- NCT01046981
- Testing
- Tumescent Antibiotic Delivery of cefazolin with or without metronidazole, Intravenous Antibiotic Delivery
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Klein, Jeffrey A., M.D.
Colostomy Stoma, Ileostomy - Stoma
Needle-Aspirated Compression Dressing Following Ostomy Reversal
Negative pressure wound dressings have been studied and shown to have applications in decreasing rates of surgical wound infections.
- Conditions
- Colostomy Stoma, Ileostomy - Stoma, Surgical Site Infection, Wound Complication
- Trial name
- NCT03703661
- Testing
- Needle-Aspirated Negative Pressure Dressing, Control
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Surgical Wound, Surgical Wound Infection
Caesarean Wound Dressing Removal Study
An open labelled randomised trial on the timing of wound dressing removal for emergency caesarean delivery in labour.
- Conditions
- Surgical Wound, Surgical Wound Infection, Cesarean Section Complications
- Trial name
- Cesarean (NCT05458518)
- Testing
- Cesarean wound dressing removal
- Where
- Malaysia
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Hospital Kemaman
Surgical Site Infection
Application of Powdered Vancomycin in the Surgical Wound in Haiti
Vancomycin, a tricyclic glycopeptide antibiotic, was originally indicated for the treatment of penicillin-resistant S. Aureus. It has a bactericidal action, inhibiting the biosynthesis of the cell wall of Gram-positive bacteria.
- Trial name
- NCT05535725
- Testing
- application of powdered vancomycin in the surgical wound as prophylaxis against the occurrence of surgical site infection
- Where
- Haiti
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Clinique Ortos
Intraabdominal Abscess After Procedure, Leakage
Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation
Despite advances in laparoscopic surgery for perforated peptic ulcer (PPU), intra-abdominal abscess (IAA) is recognized as one of the commonly reported complications with relation to the extent of infectious abdominal…
- Conditions
- Intraabdominal Abscess After Procedure, Leakage, Pneumonia, Operation Wound; Infection
- Trial name
- NCT05147870
- Testing
- Peritoneal irrigation, Suction only
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Wei-Jung
Cardiac Surgery, Bone Wax, NU-KNIT, Median Sternotomy, Deep Sternal Wound Infection, Surgical Site Infection
Surgicel NU-KNIT Vs Bone Wax on Median Sternotomy
Bone wax is traditionally used as part of surgical procedures to prevent bleeding from exposed spongy bone. It is an effective hemostatic device which creates a physical barrier.
- Trial name
- NBCS (NCT06869772)
- Testing
- Closure of sternotomy
- Where
- Qatar
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Sternal Fracture, Sternal Wound Infection
Sternal Wound Infection in Patients Undergone Sternal Fixation Using Locking Compression Plates
Sternal Wound Infection (SWI) in open heart surgery is one of the most annoying and avoidable complications that one encounters during work.
- Conditions
- Sternal Fracture, Sternal Wound Infection, Surgical Site Infection
- Trial name
- NCT05040399
- Testing
- Locking Compression Plates, Sternal Wires
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Assiut University
Surgical Wound Infection, Cesarean Wound; Dehiscence
Sucrose as a Standard in Cesarean Section Surgical Wound Healing to Reduce Hospital Time
It is a randomized, single-blind clinical trial, whose population to be studied will be randomized patients with a diagnosis of dehiscence and infection of a cesarean surgical wound who meet the inclusion and exclusion criteria.
- Trial name
- SAGRA (NCT06477770)
- Testing
- Clorhexidine soap, Sucrose
- Where
- Honduras
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Surgical Site Infection
Topical Treatment and Prevalence of P. Acnes
This study is about preventing surgical site infections of the shoulder. We hope to learn if clindamycin alone, benzoyl peroxide alone, or clindamycin and benzoyl peroxide together can affect growth of Propionibacterium acnes in…
- Trial name
- NCT03257202
- Testing
- Clindamycin 1% Gel, Benzoyl peroxide 5% gel, BenzaClin 5%-1% Topical Gel
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Surgical Site Infection
Pilot Clinical Evaluation to Characterize in Vivo Effects of Topically Applied ZuraPrep & ZuraPrep Vehicle
ZuraPrep is being evaluated for efficacy as a preoperative skin preparation solution to demonstrate its immediate and persistent antimicrobial properties.
- Trial name
- NCT02578771
- Testing
- ZuraPrep with 70% IPA, ZuraPrep without 70% IPA, ChloraPrep CHG/IPA Teal Tint
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Knee Prosthesis
Effect of Normothermia Care Bundle in Knee Replacement Surgery
Osteoarthritis is a disease characterized by disruption of the integrity of articular cartilage as a result of erosion of articular cartilage.
- Trial name
- NCT06454877
- Testing
- active heating, pasive heating
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Surgical Incision, Surgery--Complications
Zinc Oxide Versus Petrolatum Following Skin Surgery
Patients undergoing routine surgery in the Department of Dermatology for any indication on non-scalp skin and closed in linear fashion with scar greater than or equal to 4.5cm in length will be invited to participate in this…
- Conditions
- Surgical Incision, Surgery--Complications, Surgical Wound, Surgical Site Infection
- Trial name
- NCT03561376
- Testing
- Topical zinc oxide vs. petrolatum post-surgical scars
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Melissa Pugliano-Mauro