Clinical trials: Post Prostatectomy
Prostate Cancer
Darolutamide+ADT Post-RP w/o ePLND in hrPC: Briganti 2019
The goal of this clinical trial is to evaluate whether adjuvant darolutamide plus androgen-deprivation therapy (ADT) can reduce post-operative recurrence and improve disease control in high-risk prostate cancer patients-defined…
- Trial name
- NCT07282197
- Testing
- Darolutamide (BAY 1841788)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University First Hospital
Prostate Cancer
Safety and Efficacy of Irreversible Electroporation in Ablation of Prostate Cancer in Humans
Up to 16 patients with confirmed low- or intermediate risk prostate cancer scheduled for a radical prostatectomy will be asked to have the Irreversible Electroporation (IRE) procedure approximately 30 days prior to the…
- Trial name
- NCT01790451
- Testing
- Irreversible Electroporation
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- Clinical Research Office of the Endourological Society
Prostate Cancer
Stereotactic Body Radiotherapy (SBRT) Post Prostatectomy
This phase I study will assess the toxicity profile and efficacy of SBRT (Stereotactic body radiotherapy) in patients with localized prostate cancer who are considered candidates for post-prostatectomy radiation.
- Trial name
- PLUTO-MPC (NCT04848909)
- Testing
- stereotactic body radiotherapy (SBRT)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cancer of Prostate
Radiotherapy Combined With a LHRH (Ant)Agonist Versus Apalutamide in Patients With Biochemical Recurrence After RP
This is a phase II randomized, open-label study comparing salvage radiotherapy in combination with 6 months of androgen-deprivation therapy (ADT) with LHRH agonist or antagonist (arm A) versus anti-androgen therapy (AAT) with…
- Trial name
- SAVE (NCT03899077)
- Testing
- Apalutamide, Leuprorelin Acetate 45Mg Powder for Injection Suspension Vial, Goserelin Acetate 10.8 MG Subcutaneous Implant
- Where
- 9 sites in Belgium
- Volunteers
- 202 people
- Sponsor
- Cancer Research Antwerp
Prostate Cancer
Combined Apalutamide, Radiotherapy, and LHRH Agonist in Prostate Cancer Patients After Prostatectomy
This is a multicenter, randomized, open label, phase III study comparing the efficacy and safety of apatulamide combined with concomitant prostate-bed salvage radiotherapy (SRT) and androgen deprivation therapy (ADT) versus…
- Trial name
- CARLHA-2 (NCT04181203)
- Testing
- Apalutamide, Salvage radiotherapy (SRT), Luteinising Hormone Releasing Hormone agonist (LHRHa)
- Where
- 15 sites in France
- Volunteers
- 490 people
- Sponsor
- UNICANCER
Prostate Cancer, Penile Diseases
Penile Length Maintenance Post-Prostatectomy
The objective of the current study is to evaluate the efficacy of a novel, class I (ie. lowest risk, clinical studies not required) medical penile traction device in preventing loss of penile length in men undergoing…
- Trial name
- NCT03500419
- Testing
- RestoreX, No treatment
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Mayo Clinic
Pain
Effects of Perioperative B&O Suppositories on Post-op Pain and Morphine Use After Laparoscopic Prostatectomy
This study is evaluating the effect of a Belladonna and Opium suppository administered intraoperatively on post operative pain after laparoscopic radical prostatectomy for prostate cancer. This is a blinded randomized study.
- Trial name
- NCT00863928
- Testing
- belladonna 16.2 mg and opium 60 mg suppository
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Benaroya Research Institute
Prostate Cancer (Post Prostatectomy)
Effect of Education to be Provided to Patients to Undergo TURP With Mobile Application on Patient Outcomes
The aim of this study was to determine the effect of mobile application training on patient outcomes (preoperative anxiety, surgical fear, postoperative pain, hemodynamic parameters, satisfaction level and length of hospital…
- Trial name
- NCT06687538
- Testing
- Mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Prostate Cancer
FACBC Outcomes for Post Prostatectomy
Investigators will perform a study with 162 patients in whom there is a strong suspicion of prostate cancer that has returned to the body after having a prostatectomy.
- Trial name
- NCT01666808
- Testing
- FACBC, Radiation therapy
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Emory University
Recurrent Prostate Carcinoma
Multicenter Randomized Trial of 68Ga-PSMA-11 PET/CT Based SRT After Radical Prostatectomy
This phase III trial studies how well Gallium Ga 68-labeled PSMA-11 (68Ga-PSMA-11) positron emission tomography (PET)/computed tomography (CT) works in diagnosing participants with prostate cancer that has come back after…
- Trial name
- PSMA SRT (NCT03582774)
- Testing
- Best Practice, Computed Tomography, Gallium Ga 68-labeled PSMA-11
- Where
- 2 sites in United States
- Volunteers
- 193 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer
Investigation of Early Hormonotherapy Efficacy of Prostate Cancer
The purpose of this study is to determine whether early hormonotherapy is effective in the treatment of high risk prostate cancer patients after radical prostatectomy.
- Trial name
- NCT00375687
- Testing
- Triptorelin
- Where
- Lithuania
- Volunteers
- 61 people
- Sponsor
- Kaunas University of Medicine
Prostate Cancer
Radiation Therapy After Prostatectomy in Treating Patients With Stage III Prostate Cancer
Randomized phase III trial to compare treatment with or without adjuvant radiation therapy in men with stage III prostate cancer who have had radical prostatectomy and lymphadenectomy recently.
- Trial name
- NCT00394511
- Testing
- low-LET photon therapy
- Volunteers
- 408 people
- Sponsor
- National Cancer Institute (NCI)
Post-Operative in-Patients
Use of Robotic Telerounding After Operative Procedures
This research is being done to test a two-way video system mounted on top of a robot. After surgery the act of seeing and evaluating patients in the hospital is called standard "rounding".
- Trial name
- NCT00261157
- Testing
- InTouch Telerounding Robot
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of California, Davis
Post Prostatectomy Incontinence, Erectile Dysfunction Following Radical Prostatectomy
Pelvic Floor Muscle Training With Aerobic Exercise and Relaxation After Radical Prostatectomy
Post-prostatectomy urinary incontinence (PP-UI) and erectile dysfunction (ED) are common complications after radical prostatectomy, negatively affecting quality of life.
- Trial name
- PFMTinPPUI (NCT07172854)
- Testing
- Pelvic Floor Muscle Training, Aerobic Exercise, Relaxation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Hacettepe University
Prostate Adenocarcinoma
A Study of Effects of Fesoterodine in Men at High Risk for Overactive Bladder/Detrusor Overactivity Post Robotic-Assisted Lap. Prostatectomy
The investigators will assess the incidence of Overactive Bladder/Detrusor Overactivity (OAB/DO) post-operatively in patients post robotic assisted radical prostatectomy (RARP) and to investigate whether fesoterodine will alter…
- Trial name
- NCT01661166
- Testing
- Fesoterodine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Pelvic Floor Disorders, Urinary Incontinence
Pelvic Floor Muscles Training After Radical Prostatectomy.
Prostate cancer (PCa) is a malignant tumor commonly diagnosed among men in the USA and Europe. About 81% of cases of prostate cancer are detected early on, which allows patients to receive effective treatment.
- Conditions
- Pelvic Floor Disorders, Urinary Incontinence, Prostatectomy
- Trial name
- NCT04172519
- Testing
- Pre- and post prostatectomy supervised PMFT, Unsupervised PMFT, Supervised PMFT
- Where
- 2 sites in Poland
- Volunteers
- 76 people
- Sponsor
- Nicolaus Copernicus University
Prostate Cancer (Post Prostatectomy)
The Application of Somatosensory Interactive Pelvic Floor Muscle Training for Stress Urinary Incontinence in Men Underwent Radical Prostatectomy
The study aims to compare the efficacy of different pelvic floor muscle training (PFMT) modes on improving urinary incontinence (UI) recovery in prostate cancer (PCa) patients after radical prostatectomy (RP).
- Trial name
- NCT06740071
- Testing
- somatosensory interactive pelvic floor muscle training, pelvic floor magnetic stimulation therapy, standard pelvic floor muscle training
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Adenocarcinoma of the Prostate, Recurrent Prostate Cancer
Hormone Therapy and Temsirolimus in Treating Patients With Relapsed Prostate Cancer
This phase I trial is studying the side effects and best dose of temsirolimus when given together with hormone therapy in treating patients with relapsed prostate cancer. Androgens can cause the growth of prostate cancer cells.
- Trial name
- NCT00512668
- Testing
- leuprolide acetate, goserelin acetate, bicalutamide
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Cancer Institute (NCI)
Prostate Neoplasm, Prostatectomy
Efficacy of Extracorporeal Biofeedback Device for Post-prostatectomy Incontinence
To evaluate the efficacy of postoperative pelvic floor muscle training using personalized extracorporeal biofeedback device among patients with post-prostatectomy incontinence
- Conditions
- Prostate Neoplasm, Prostatectomy, Surgical Procedures, Robotic, Urinary Incontinence
- Trial name
- NCT02485665
- Testing
- Extracorporeal biofeedback device (Any Kegel)
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Seoul National University Hospital
Urinary Incontinence
Predictor of Early Recovery on Urinary Continence After Laparoscopic Radical Prostatectomy
To investigate the relationship between post-operative bladder neck levels and urodynamic parameters and their effect on urinary incontinence after laparoscopic radical prostatectomy (LRP).
- Trial name
- NCT03097367
- Testing
- bladder neck level on cystography
- Volunteers
- 48 people
- Sponsor
- Buddhist Tzu Chi General Hospital