Clinical trials: Post Prostatectomy
Prostate Cancer
Stereotactic Body Radiotherapy (SBRT) Post Prostatectomy
This phase I study will assess the toxicity profile and efficacy of SBRT (Stereotactic body radiotherapy) in patients with localized prostate cancer who are considered candidates for post-prostatectomy radiation.
- Trial name
- PLUTO-MPC (NCT04848909)
- Testing
- stereotactic body radiotherapy (SBRT)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sunnybrook Health Sciences Centre
Erectile Dysfunction Following Radical Prostatectomy
Low-intensity Shockwave Therapy for Post-radical Prostatectomy Erectile Dysfunction
This research study is trying to determine if Low-Intensity shock wave therapy (LiSWT) is safe and effective in patients with symptoms of erectile dysfunction (ED) after radical prostatectomy.
- Trial name
- NCT06219785
- Testing
- Low-Intensity Shockwave therapy (LiSWT)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The Methodist Hospital Research Institute
Prostate Cancer, Erectile Dysfunction
A Yoga Program for Patients Undergoing Prostate Cancer Surgery
Men with localized prostate cancer (PCa) are often treated with surgery, a treatment that is associated with high rates of side effects such as erectile dysfunction (ED) and urinary incontinence (UI) which impact quality of life.
- Conditions
- Prostate Cancer, Erectile Dysfunction, Urinary Incontinence
- Trial name
- NCT05929300
- Testing
- Yoga, Usual Care
- Where
- United States
- Sponsor
- VA Office of Research and Development
Men Who Have Undergone Prostatectomy
Postural Training for Standing and Sitting in Men Suffering From Post-prostatectomy Urinary Incontinence
Existing research highlights the difficulty of identifying an optimal rehabilitation technique for improving male urinary continence.
- Trial name
- EDULAPRO (NCT06842914)
- Testing
- postural training
- Where
- 2 sites in France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Rouen
Urinary Incontinence
A Study to Assess Efficacy and Safety With Solifenacin Succinate to Improve Urinary Continence After Robotic Assisted Radical Prostatectomy
The purpose of this study is to assess the efficacy and safety of 12 weeks of treatment of solifenacin succinate versus placebo in participants who are incontinent after Robotic Assisted Radical Prostatectomy.
- Trial name
- NCT01371994
- Testing
- solifenacin succinate
- Where
- 60 sites in United States, Canada
- Volunteers
- 640 people
- Sponsor
- Astellas Pharma Inc
Stress Incontinence, Male
Pilates Training and Low Intensity Shock Wave Therapy for Post-prostatectomy Stress Incontinence
120 Patients with urinary incontinence following radical prostatectomy would be randomly assigned to either 4 groups all receive conventional pelvic floor muscle exercises plus group A receive Pilates exercises and Low Intensity…
- Trial name
- Incontinence (NCT06322082)
- Testing
- The DUOLITH SD1-TOP focused shock wave system (STORZ MEDICAL AG)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Khadra Mohamed Ali
Stress Urinary Incontinence
Periurethral Pro-ACTTM Balloons vs Retrourethral AdvanceXP(TM) Male Sling for Post-prostatectomy Incontinence
Background: Periurethral Pro-ACT balloons and retrourethral AdvanceXP(TM) male sling have been presented as efficient treatments for management of stress urinary incontinence (SUI) following radical prostatectomy (RP), but no…
- Trial name
- BALLANCE (NCT01500603)
- Testing
- AdvanceXP Male sling device, Pro-ACT balloon device
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prostatectomy, Cystectomy
Hugo™ RAS Urology Post-Market Clinical Study
The purpose of this study is to collect evidence on the safety and performance of the Medtronic Hugo™ RAS System when used for urologic RAS procedures.
- Conditions
- Prostatectomy, Cystectomy, Nephrectomy, Urologic Cancer
- Trial name
- NCT07901049
- Testing
- Robotic Assisted Urologic Surgery
- Volunteers
- 110 people
- Sponsor
- Medtronic - MITG
Prostate Cancer, Venous Thromboembolism
PREvention of VENous ThromboEmbolism Following Radical Prostatectomy
The PREVENTER Trial aims to compare the use of perioperative pharmacologic prophylaxis (subcutaneous heparin) with intermittent pneumatic compression devices (IPCs) to the use of IPCs alone for the prevention of venous…
- Conditions
- Prostate Cancer, Venous Thromboembolism, Lymphocele After Surgical Procedure, Deep Venous Thrombosis
- Trial name
- PREVENTER (NCT03006562)
- Testing
- Subcutaneous Heparin
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Johns Hopkins University
Recurrent Prostate Cancer After Surgery
This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned.
There is significant, proven use of radiation for recurrent prostate cancer after surgical resection. This treatment typically is delivered over seven and a half weeks of daily treatments, presenting a burden to patients and the…
- Trial name
- DASBRT-RPC (NCT05946824)
- Testing
- Daily-adaptive Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Prostate Cancer
dMD-002 Pilot Study in Patients With Cavernous Nerve Injury Following Radical Prostatectomy
The purpose of this study is to conduct a US Pilot study of dMD-002 as a peripheral nerve repair sheet in patients with cavernous nerve injury following radical prostatectomy.
- Trial name
- NCT07564102
- Testing
- dMD-002, Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mochida Medical USA, Inc.
Prostate Cancer
Samarium Sm 153 Lexidronam Pentasodium and 3-Dimensional Conformal Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Rising Prostate-Specific Antigen Levels After Radical Prostatectomy for Prostate Cancer
RATIONALE: Giving samarium Sm 153 lexidronam pentasodium and 3-dimensional (3-D) conformal radiation therapy or intensity-modulated radiation therapy may keep prostate cancer from growing in patients with rising prostate-specific…
- Trial name
- NCT00551525
- Testing
- Radiotherapy, Samarium 153
- Where
- 29 sites in United States
- Volunteers
- 67 people
- Sponsor
- Radiation Therapy Oncology Group
Biochemically Recurrent Prostate Carcinoma, Prostate Adenocarcinoma
Radioligand Therapy After PSMA PET Guided External Beam Radiotherapy for Treating Post-Prostatectomy Patients With Biochemically Recurrent Prostate Cancer
This phase I trial tests the safety, side effects and best dose of radioligand therapy (lutetium Lu 177 PSMA-10.1 [177Lu-rhPSMA-10.1]) after prostate specific membrane antigen (PSMA) positron emission tomography (PET)-guided…
- Trial name
- NCT06105918
- Testing
- Biospecimen Collection, Computed Tomography, External Beam Radiation Therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Emory University
Recurrent Prostate Cancer
Trial of Ultrahypofractionated Focal Salvage Radiotherapy for Isolated Prostate Bed Recurrence After Radical Prostatectomy
The main objective of the trial is to explore the efficacy and safety of combining short-term androgen deprivation therapy (ADT) over 6 months to focal ultrahypofractionated salvage radiotherapy (SRT) delivered in 5 fractions to…
- Trial name
- HypoFocal SRT (NCT05746806)
- Testing
- Ultrahypofractionated salvage radiotherapy to a local recurrence after radical prostatectomy, Androgen deprivation therapy
- Where
- 5 sites in Switzerland
- Volunteers
- 36 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Erectile Dysfunction
Clinical Trial of Low Intensity Shockwaves Therapy for Erectile Dysfunction Post-Radical Prostatectomy
Research study designed to learn about and compare Shockwave therapy (SWT) vs placebo (no shockwaves) treatment in men with moderate to severe erectile dysfunction (ED) after Radical Prostatectomy
- Trial name
- NCT06152146
- Testing
- Shockwave Therapy
- Where
- United States
- Sponsor
- University of Miami
Localized Prostate Cancer, Postoperative Urinary Incontinence
Oxybutynin ER to Promote Early Continence Recovery After Robotic Prostatectomy: A Randomized Controlled Trial
The goal of this double-blind, randomized, placebo-controlled study is to evaluate whether oxybutynin chloride extended-release tablets can improve early continence recovery after robot-assisted radical prostatectomy (RARP) in…
- Trial name
- NCT06966778
- Testing
- Oxybutynin chloride extended-release tablets 5mg/tab, 2 tab, PO, qd.
- Where
- Taiwan
- Volunteers
- 135 people
- Sponsor
- National Taiwan University Hospital
Prostate Cancer
Urodynamic Evaluation in Post-radiation Salvage Prostatectomy Patients
Objectives: The primary objective of this study is to determine whether bladder compliance is significantly lower in men who undergo prostatectomy for recurrence following primary radiation therapy than in men who undergo…
- Trial name
- NCT00901420
- Testing
- Urodynamics Test, Questionnaire
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- M.D. Anderson Cancer Center
Prostatic Neoplasms, Prostatectomy
Impact of Tamsulosin on Voiding Patterns Following Early Catheter Removal After Robot-assisted Laparoscopic Radical Prostatectomy
To date, there is a lack of consensus concerning the optimal timing for removal of the urethral catheter, its related complications, the effectiveness in prophylactic drug use to reduce complication, and the patient reported…
- Trial name
- NCT01209988
- Testing
- tamsulosin 0.4mg, No medication
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Asan Medical Center
Prostatic Adenocarcinoma
Prediction of the Risk of Biochemical Relapse After Radical Prostatectomy for Prostate Cancer Using Radomics on Pre-therapeutic MRI
With 50% of post-operative biochemical failure, efficient predictive models are needed to guide post-operative management. Radiomic features are quantitative features extracted from medical imaging, supposed to be correlated with…
- Trial name
- PREBOP (NCT04063800)
- Where
- 2 sites in France
- Volunteers
- 195 people
- Sponsor
- University Hospital, Brest
Urinary Incontinence, Post Prostatectomy
Radiofrequency in the Treatment of Urinary Incontinence After Radical Prostatectomy
Post-prostatectomy urinary incontinence (IUPP) is a difficult to treat complication that causes a profound negative impact on the individual's quality of life, as well as seriously disrupts the physician-patient relationship and…
- Trial name
- NCT03048799
- Testing
- Radiofrequency
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Centro de Atenção ao Assoalho Pélvico