Clinical trials: Post Prostatectomy
Prostate Cancer
The Role of Levator Ani Muscle Reconstruction Technology in Urinary Incontinence Recovery
This study is a single center, single blind, prospective randomized controlled trial. Patients undergoing robot assisted laparoscopic radical prostatectomy for prostate cancer were randomly divided into 1:1:1 groups, using…
- Trial name
- NCT06543420
- Testing
- lateral reconstruction, posterior reconstruction
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Peking University First Hospital
Prostate Cancer
Shorter Duration Radiotherapy to Treat Prostate Cancer After Removal of the Prostate
Radiation therapy is one of the standard treatments for men with prostate cancer who have detectable levels of prostate specific antigen (PSA, a prostate cancer specific marker) after surgery.
- Trial name
- HypoFX (NCT01868386)
- Testing
- Hypofractionated therapy
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Timothy Showalter, MD
Prostate Cancer
Soy Protein in Preventing Recurrent Cancer in Patients Who Have Undergone Surgery for Stage II Prostate Cancer
RATIONALE: Soy protein may help prevent prostate cancer recurrence in patients who have undergone surgery for prostate cancer. PURPOSE: This randomized phase II/III trial is studying how well soy protein works and compares it to…
- Trial name
- NCT00765479
- Testing
- soy protein isolate
- Where
- United States
- Volunteers
- 284 people
- Sponsor
- University of Illinois Chicago
Prostate Cancer
11C Acetate Imaging Post Prostatectomy
This research is being conducted to test an imaging technique that may be able to detect small amounts of prostate cancer that can not be detected by standard imaging.
- Trial name
- NCT01602783
- Testing
- 11C Acetate Imaging
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital
Urinary Incontinence (UI)
Urinary Incontinence After Endoscopic Prostatectomy
This is a prospective cohort study aiming to identify the preoperative and intraoperative predictors of urinary incontinence after endoscopic transurethral bipolar prostatectomy
- Trial name
- NCT06939140
- Testing
- Bipolar prostatectomy
- Where
- Egypt
- Volunteers
- 133 people
- Sponsor
- Assiut University
Erectile Dysfunction
Clinical Trial of Low Intensity Shockwaves Therapy for Erectile Dysfunction Post-Radical Prostatectomy
Research study designed to learn about and compare Shockwave therapy (SWT) vs placebo (no shockwaves) treatment in men with moderate to severe erectile dysfunction (ED) after Radical Prostatectomy
- Trial name
- NCT06152146
- Testing
- Shockwave Therapy
- Where
- United States
- Sponsor
- University of Miami
Prostate Cancer
Decision Impact Study to Measure the Influence of DECIPHER on Treatment Recommendations
This clinical utility study pilot is based on a review of real but de-identified and randomized patient cases and aims to evaluate Urologists' treatment recommendations before and after reviewing the results provided by the…
- Trial name
- DECIDE (NCT02020876)
- Testing
- DECIPHER Questionnaire
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- GenomeDx Biosciences Corp
Neuromuscular Blockade
Deep Neuromuscular Blockade During Robotic Radical Prostatectomy
Basic requirement for safe performance of the robotic intra-abdominal surgery is a calm and clear surgical field after the introduction of a capnoperitoneum. That can be enabled by a neuromuscular blockade.
- Trial name
- NCT02513693
- Testing
- Standard neuromuscular blockade, Deep neuromuscular blockade
- Where
- 2 sites in Czechia
- Volunteers
- 80 people
- Sponsor
- Palacky University
Prostate Cancer, Urinary Incontinence
Pre-Operative Nurse-Led Education With Direct Physiotherapy Referral to Reduce Post-Prostatectomy Incontinence
Urinary incontinence is a common complication following radical prostatectomy and can significantly impact quality of life. Pelvic floor physiotherapy is recommended to reduce post-operative incontinence; however, referral…
- Conditions
- Prostate Cancer, Urinary Incontinence, Postoperative Complications, Radical Prostatectomy
- Trial name
- PRO-ACT (NCT07426861)
- Testing
- Standard Pre-Operative Education and Physiotherapy Recommendation, Pre-Operative Nurse-Led Education with Direct Physiotherapy Referral
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- Royal College of Surgeons, Ireland
Post Spinal Anaesthesia Hypotension, Transurethral Resection of the Prostate (TURP)
Ultrasound Assessment of Femoral Vein and Inferior Vena Cava Collapsibility to Predict Spinal Anesthesia-Induced Hypotension
Spinal anesthesia is commonly used in transurethral prostate resection (TUR-P) surgeries; however, post-spinal hypotension remains a frequent and clinically significant complication, particularly in elderly patients.
- Trial name
- NCT07497295
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Antalya Training and Research Hospital
Prostatic Cancer, Pain, Postoperative
Quadratus Lumborum Block vs Transversus Abdominis Plane Block for Post-prostatectomy Analgesia
Recently, the uses of peripheral axial blocks that deliver local anesthetic into the transversus abdominis fascial plane have become popular for operations that involve incision(s) of the abdominal wall.
- Conditions
- Prostatic Cancer, Pain, Postoperative, Pain, Anesthetics, Local
- Trial name
- NCT03606889
- Testing
- Quadratus Lumborum block, Tranversus Abdominis plane block, Bupivacaine
- Where
- Poland
- Volunteers
- 12 people
- Sponsor
- Jagiellonian University
Prostatic Neoplasms
Exisulind Versus Placebo After Surgical Removal of the Prostate
This is a study in which patients with prostate cancer treated by surgical removal of the prostate and considered to be at risk for prostate cancer recurrence will receive Exisulind 250 mg twice a day or placebo twice a day for…
- Trial name
- NCT00166426
- Testing
- Exisulind
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Mayo Clinic
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy
Improving Erectile Function and Quality of Life After Prostate Cancer Treatment
This is a research study of erectile dysfunction (ED) in men diagnosed with prostate cancer. 144 patients and partners will participate in the study.
- Conditions
- Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Following Simple Prostatectomy, Erectile Dysfunction
- Trial name
- NCT01996852
- Testing
- Cognitive-behavioral Meetings, sildenafil citrate, Vacuum Constriction Device
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Case Comprehensive Cancer Center
Prostatectomy, Opioid-Related Disorders
Pre-operative Education Modalities to Decrease Opioid Use
This is a triple-armed, randomized, controlled, non-blinded trial to study the effect of preoperative patient education in conjunction with a limited opioid peri-operative analgesia program on post-operative opioid use following…
- Trial name
- NCT04933084
- Testing
- Pre-operative Opioid Education
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Pain, Postoperative
Spinal Morphine for Postoperative Analgesia in Urology
The study was performed in urology patients elicited for open prostatectomy or open nephrectomy. Comparison of analgesic effect between group (M) with spinal morphine before general anaesthesia and group without this intervention…
- Trial name
- NCT03675646
- Testing
- Morphine
- Where
- Czechia
- Volunteers
- 98 people
- Sponsor
- Charles University, Czech Republic
Urinary Incontinence, Prostate Cancer
Evaluation of a Postural Rehabilitation Program Based on Sensory-motor Control in Men With Urinary Incontinence After Prostatectomy
Urinary incontinence (UI) is defined by the International Continence Society as "any involuntary loss of urine complained by the patient".
- Trial name
- PROTOMEN (NCT03027986)
- Testing
- postural rehabilitation program
- Where
- France
- Sponsor
- University Hospital, Rouen
Prostate Cancer (Post Prostatectomy), Perioperative Anesthetic
Effects of Rectal Indomethacin Suppository on Postoperative CRBD in Patients Undergoing LRP
The postoperative incidence of catheter-related bladder discomfort (CRBD) ranges from 47% to 95%. It increases postoperative pain and agitation, thus requiring early intervention.
- Conditions
- Prostate Cancer (Post Prostatectomy), Perioperative Anesthetic, Catheter-related Bladder Discomfort (CRBD)
- Trial name
- NCT07607990
- Testing
- Indomethacin suppository
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Zhejiang University
Prostate Cancer, Urinary Incontinence
A Prospective Evaluation of Early Acupuncture for Immediate Continence Enhancement After Prostatectomy
This study is being done to see if early acupuncture treatment can help men control their urination better right after their urinary catheter is removed following prostate cancer surgery (radical prostatectomy).
- Trial name
- PEACE (NCT07239518)
- Testing
- Electroacupuncture
- Volunteers
- 144 people
- Sponsor
- Bin Xu
Anesthesia, Surgery
Low Dose Versus Normal Dose Ketorolac for Postoperative Pain After Prostatectomy and Hysterectomy
A monocenter, prospective, double-blind, randomized controlled non-inferiority trial will be designed to investigate if ketorolac 10 mg is as effective for pain relief as the standard dose of 30 mg in patients undergoing robot…
- Trial name
- NCT05206110
- Testing
- 10 mg IV ketorolac, 30 mg IV ketorolac
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Jessa Hospital
Erectile Dysfunction
A Study of Tadalafil After Radical Prostatectomy
The study will include patients with localized prostate cancer who experience erectile dysfunction following bilateral nerve-sparing radical prostatectomy.
- Trial name
- REACTT (NCT01026818)
- Testing
- Tadalafil
- Where
- 52 sites in Belgium, Canada and 8 more
- Volunteers
- 583 people
- Sponsor
- Eli Lilly and Company