Clinical trials: Post Prostatectomy
Prostate Cancer
Ability of Cardio Q for Prediction of Hypotension
Evaluation the ability of each indicator of Cardio Q in predicting hypotension after position changes in robot-assisted laparoscopic radical prostatectomy
- Trial name
- NCT03882697
- Where
- 2 sites in South Korea
- Volunteers
- 125 people
- Sponsor
- Severance Hospital
Prostate Cancer, Biochemical Recurrence
Salvage Radiotherapy Combined With Androgen Deprivation Therapy (ADT) With or Without Rezvilutamide in the Treatment of Biochemical Recurrence After Radical Prostatectomy for Prostate Cancer
To evaluate the efficacy and safety of rezvilutamide in combination with androgen deprivation therapy(ADT) and standard salvage radiation therapy(SRT) or SRT combination with ADT in prostate cancer patients with biochemical…
- Trial name
- NCT06305832
- Testing
- Rezvilutamide, Androgen deprivation therapy (ADT), SRT
- Where
- 2 sites in China
- Volunteers
- 102 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Prostate Cancer, Biochemical Relapse Fo Malignant Neoplasm of Prostate
PSMA Guided Approach for bIoCHEmical Relapse After Prostatectomy-PSICHE
This observational study was designed to evaluate progression free survival after PSMA-PET/CT based salvage approach for patients affected by biochemical relapse after radical prostatectomy.
- Conditions
- Prostate Cancer, Biochemical Relapse Fo Malignant Neoplasm of Prostate, Prostate Adenocarcinoma, Prostate Cancer Recurrent
- Trial name
- PSICHE (NCT05022914)
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Prostate Adenocarcinoma
The Use of Ultrasound in Assessing Post-prostatectomy Erectile Dysfunction
Researchers are trying to determine whether there is additional utility to using vibroelastography, a noninvasive ultrasound technique to evaluate for the presence of tissue fibrosis, in conjunction with standard penile duplex…
- Trial name
- NCT05109208
- Testing
- Ulrasound Vibroelastography (UVE)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Prostate Cancer
Decision Impact Study to Measure the Influence of DECIPHER on Treatment Recommendations for Radiation Oncologists
This clinical utility study is based on a review of real but de-identified and randomized patient cases and aims to evaluate radiation oncologist's treatment recommendations before and after reviewing the results provided by the…
- Trial name
- DECIDE3 (NCT02034812)
- Testing
- Decipher Questionnaire
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GenomeDx Biosciences Corp
Prostate Cancer
PSMA-PET Guided De-escalation of Salvage Radiation Treatment in Recurrent Prostate Cancer
Purpose: Prospective, single-site Phase II study testing whether PSMA-PET/MRI-guided, de-escalated salvage radiation reduces acute Grade ≥2 toxicity versus a 44% historical rate, while maintaining cancer control after…
- Trial name
- NCT07234981
- Testing
- PSMA-guided Salvage Radiation
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Nebraska
Erectile Dysfunction
Low Frequency Shock Wave Therapy for Improving Post-prostatectomy Erectile Dysfunction: a Prospective Pilot Study
The primary objective of this study is to evaluate changes in erectile function (EF) before versus after 8 bi-weekly treatments of Low-Intensity Extracorporeal Shock Wave Therapy (LIESWT) via IIEF-EF (the Erectile Function domain…
- Trial name
- ProstaChoc 1 (NCT02746094)
- Testing
- 8 bi-weekly LIESWT sessions
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Prostate Cancer Recurrent
Salvage Lymph Node Dissection in Prostate Cancer Patients With Recurrence After Radical Prostatectomy
Despite continuous technical improvements in urologic surgery, up to 40% of prostate cancer patients will develop biochemical recurrence after radical prostatectomy (RP), potentially because of micro metastasis at the time of the…
- Trial name
- NCT02974075
- Testing
- Salvage lymph node dissection
- Where
- Austria
- Volunteers
- 65 people
- Sponsor
- Medical University of Vienna
Prostate Cancer
Does Postoperative Gabapentin Reduce Pain, Opioid Consumption and Anxiety and Have a Positive Effect on Health Related Quality of Life After Radical Prostatectomy?
The Acute Pain Service (APS) at Sunnybrook has been using Gabapentin 200 mg three times a day (TID) resulting in anecdotal benefits in terms of analgesia and opioid sparing effects.
- Trial name
- NCT00982800
- Testing
- Gabapentin
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Prostate Cancer (CRPC), Peak Expiratory Flow
Comparison of Peak Expiratory Flow Changes After Robot-Assisted Versus Open Radical Prostatectomy
This prospective, randomized controlled trial aims to compare perioperative respiratory changes in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALRP) and open radical prostatectomy (ORP).
- Trial name
- NCT07262073
- Testing
- Surgical procedure: Robot-assisted laparoscopic radical prostatectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Prostatic Cancer, Surgical Procedure, Unspecified
Early Urinary Continence After Radical Prostatectomy: Surgical Procedure and Anatomic Landmarks
This study describes how to perform a correct prostatic apex and membranous urethra in order to preserve all anatomical elements that are necessary to achieve a very fast urinary continence after open/laparoscopic/robotic radical…
- Conditions
- Prostatic Cancer, Surgical Procedure, Unspecified, Urinary Incontinence
- Trial name
- NCT04043637
- Volunteers
- 120 people
- Sponsor
- Consorci Sanitari Integral
Urinary Incontinence, Stress
A Pre-Market Study of the American Medical Systems (AMS) Transobturator Male Sling System for the Treatment of Male Stress Urinary Incontinence
The purpose of this study is to obtain surgical technique data for use in physician education and training and to collect early clinical outcomes data for future publication.
- Trial name
- AMS051 (NCT00904969)
- Testing
- The AMS Male Transobturator Sling System, AdVance Male Sling
- Where
- 11 sites in United States, Canada
- Volunteers
- 55 people
- Sponsor
- American Medical Systems
Prostate Cancer
Brassica Vegetables or Indole-3-Carbinol in Treating Patients With PSA Recurrence After Surgery for Prostate Cancer
RATIONALE: Eating a diet high in vegetables may lower the risk of some types of cancer. Brassica vegetables (such as cabbages, kale, broccoli, Brussels sprouts, and cauliflower) and indole-3-carbinol (a substance found in…
- Trial name
- NCT00607932
- Testing
- behavioral dietary intervention, Brassica vegetable, indole-3-carbinol
- Volunteers
- 66 people
- Sponsor
- Vanderbilt University
Urinary Incontinence
Prevention of Urinary Incontinence After Prostatectomy
Urinary incontinence is a frequent complication after radical prostatectomy. Rehabilitative treatments are frequently utilized to reduce incontinence. However, their efficacy has not been completely investigated.
- Trial name
- NCT00982098
- Testing
- BioFeedback; Functional Electrical Stimulation; Pelvic Floor Muscle training exercises
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Prostatic Neoplasms, ctDNA
Prognostic Study of Via Dynamic Change of dT-DNA in Drainage Fluid After Radical Prostatectomy
This study investigates the prognostic value of dynamic changes in Drainage Tumor DNA(dT-DNA) levels found in the peritoneal drainage fluid after radical prostatectomy.
- Trial name
- NCT06707974
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Post-Prostatectomy Incontinence, Urinary Stress Incontinence
Prospective Pilot ATOMS vs AUS
Post-Prostatectomy Incontinence (PPI) is a common complication affecting 1% to 40% of patients after surgery. When conservative treatments fail, the installation of an artificial urinary sphincter (AUS) has been the treatment of…
- Conditions
- Post-Prostatectomy Incontinence, Urinary Stress Incontinence, Urinary Incontinence, Stress Incontinence, Male
- Trial name
- NCT05464316
- Testing
- Adjustable Transobturator Male System, Artificial Urinary Sphincter
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Université de Sherbrooke
Urinary Incontinence Following Surgical Procedure
A PSM Analysis to Evaluate Electrical Pudendal Nerve Stimulation for PPI
The goal of this propensity score matching study is to compare the posttreatment outcomes of post-radical prostatectomy Incontinence patients undergoing either electrical pudendal nerve stimulation or pelvic floor muscle training…
- Trial name
- NCT06130306
- Testing
- electrical pudendal nerve stimulation, pelvic floor muscle training combined with transanal electrical stimulation
- Where
- China
- Volunteers
- 389 people
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Incontinence, Urinary, Radical Prostatectomy
Urinary Incontinence After Radical Prostatectomy
The aims of this project are; 1) To examine the efficacy of ultrasound-guided pelvic floor muscle training compared to standard care on urinary incontinence in patients undergoing robot assisted radical prostatectomy and 2) To…
- Trial name
- NCT05625048
- Testing
- Transperinal ultrasound guided instruction in pelvic floor muscle training
- Where
- Denmark
- Volunteers
- 66 people
- Sponsor
- Regional Hospital West Jutland
Prostate Cancer, Biochemical Recurrence
Predictors of BCR After RARP for Localized Prostate Cancer: A Retrospective Analysis
This retrospective study aims to identify predictive factors for biochemical recurrence (BCR) in patients with localized prostate cancer who underwent robot-assisted radical prostatectomy (RARP).
- Trial name
- NCT07682584
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Prostate Cancer (Post Prostatectomy), Prostate Cancer
RIsk aDapted Stereotactic Radiotherapy vs. standarD of Care Radiotherapy in Patients With Prostate Cancer in the Adjuvant or saLvage sEtting With or Without Lymph Node Irradiation (RIDDLELN) - A Phase III Trial
The goal of this clinical trial is to determine whether stereotactic body radiotherapy (SBRT) delivered in five fractions is non-inferior to standard-of-care mildly hypofractionated radiotherapy in terms of patient-reported…
- Conditions
- Prostate Cancer (Post Prostatectomy), Prostate Cancer, SBRT
- Trial name
- RIDDLELN (NCT07830511)
- Testing
- Stereotactic body radiotherapy (SBRT) to the prostate bed, Standard-of-care radiotherapy (SOC) to the prostate bed
- Volunteers
- 206 people
- Sponsor
- Robert Förster