Clinical trials: Post Prostatectomy
Erectile Dysfunction, Prostate Cancer
A Safety and Efficacy Study of Prograf in the Prevention of Erectile Dysfunction After Radical Prostatectomy
The purpose of the study is to compare the safety and effectiveness of Prograf in the prevention of erectile dysfunction in men after a radical prostatectomy.
- Trial name
- NCT00106392
- Testing
- Tacrolimus
- Where
- 6 sites in United States
- Volunteers
- 131 people
- Sponsor
- Astellas Pharma Inc
Prostate Cancer, Venous Thromboembolism
PREvention of VENous ThromboEmbolism Following Radical Prostatectomy
The PREVENTER Trial aims to compare the use of perioperative pharmacologic prophylaxis (subcutaneous heparin) with intermittent pneumatic compression devices (IPCs) to the use of IPCs alone for the prevention of venous…
- Conditions
- Prostate Cancer, Venous Thromboembolism, Lymphocele After Surgical Procedure, Deep Venous Thrombosis
- Trial name
- PREVENTER (NCT03006562)
- Testing
- Subcutaneous Heparin
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Johns Hopkins University
Urinary Incontinence
The Effects of Neuromuscular Electrical Stimulation in Individuals With Urinary Incontinence After Prostatectomy
The aim of this study is to investigate the effects of neuromuscular electric stimulation on urinary symptoms, quality of life, sexual function, perception of improvement and patient satisfaction in individuals with…
- Trial name
- NCT05236088
- Testing
- Neuromuscular electrical stimulation application
- Volunteers
- 50 people
- Sponsor
- Ankara Yildirim Beyazıt University
Metastatic Prostate Cancer, Prostate Cancer (Adenocarcinoma)
CONVERT-HB1: Radical Prostatectomy After Systemic Therapy for High-volume Metastatic Hormone-sensitive Prostate Cancer
This is a prospective, randomized, open-label, phase II multicenter clinical trial evaluating the efficacy and safety of radical prostatectomy in patients with high-volume metastatic hormone-sensitive prostate cancer (mHSPC) who…
- Conditions
- Metastatic Prostate Cancer, Prostate Cancer (Adenocarcinoma), Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
- Trial name
- CONVERT-HB1 (NCT07268794)
- Testing
- Androgen Deprivation Therapy (ADT), Docetaxel, PARP Inhibitors and Other Systemic Agents
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Fudan University
Delayed Graft Function
Can Fat Derived Stem Cells (SVF) be Used in the Treatment of Erectile Dysfunction After Prostatectomy
Prostate cancer is the most common cancer among Danish men, and the incidence is increasing. Studies have shown a high number needed to treat for each saved prostate cancer related death.
- Trial name
- NCT02240823
- Testing
- adipose derived stem cells
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Martha Haahr M.D
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy
This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate…
- Trial name
- NCT07863388
- Testing
- Autologous Platelet Rich Plasma
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev and Gentofte Hospital
Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy
MENDiP: Measurements of Overnight Penile Temperature to Evaluate Nocturnal Erection Detection in Patients With Absence of Erectile Functioning After Robot-assisted Radical Prostatectomy
Nocturnal erection detection with the outdated RigiScan is the golden standard for erectile dysfunction (ED) nature differentiation.
- Trial name
- MENDiP (NCT05578157)
- Testing
- Feeling Hot sensor
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- St. Antonius Hospital
Urinary Incontinence
ProACT Therapy for the Treatment of Stress Urinary Incontinence in Males
The purpose of the study is to evaluate the safety and effectiveness of a minimally invasive surgical procedure in up to 109 male patients.
- Trial name
- ProACT (NCT00277095)
- Testing
- ProACT (Adjustable Continence Therapy)
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Uromedica
Stress Urinary Incontinence, Radical Prostatectomy
Data Collection Post Radical Prostatectomy
The study is designed to collect information on patients undergoing radical prostatectomy (RP), with a primary focus on the occurrence, duration, and severity of post-prostatectomy incontinence.
- Conditions
- Stress Urinary Incontinence, Radical Prostatectomy, BPH
- Trial name
- ALTO (NCT06351579)
- Testing
- Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Levee Medical, Inc.
Prostate Cancer With Radical Prostatectomy
The Efficacy and Safety of Udenafil in Patients With Erectile Dysfunction After Bilateral Nerve-sparing Radical Prostatectomy
This study evaluates the efficacy and safety of Udenafil dosed once a day in patients with erectile dysfunction after bilateral nerve-sparing radical prostatectomy.
- Trial name
- DA8159_EDP_IIT (NCT03142542)
- Testing
- ZYDENA TAB.75mg(Udenafil 75mg)
- Volunteers
- 99 people
- Sponsor
- Samsung Medical Center
Prostate Cancer
Study of Peri-Operative Docetaxel Plus Laparoscopic Radical Prostatectomy in Prostate Cancer Patients
This is a prospective phase II study of peri-operative docetaxel plus laparoscopic radical prostatectomy in patients with localized Gleason 7 pT2a-pT2b adenocarcinoma of the prostate and a risk of relapse after radical…
- Trial name
- NCT00127088
- Testing
- docetaxel, laparoscopic radical prostatectomy
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Postoperative Pain
Rectus Sheath Block: Postoperative Analgesia and Proinflammatory Cytokines
Good quality of postoperative analgesia would lead to attenuate or prevent the adverse effects on the common functions of the immune system.
- Trial name
- NCT03074097
- Testing
- Bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Prostate Cancer
Phase II Study of DCVAC/PCa Added After Radical Primary Prostatectomy for Patients With Localized Prostate Cancer
The purpose of this study is to determine whether DCVAC/PCa added after radical primary prostatectomy can improve PSA doubling times for patients with localized Prostate Cancer.
- Trial name
- NCT02107404
- Testing
- Dendritic Cells DCVAC/PCa
- Where
- 11 sites in Czechia
- Volunteers
- 150 people
- Sponsor
- SOTIO a.s.
Prostate Cancer Patients Undergoing Radical Prostatectomy
Prehabilitation for Prostate Cancer Surgery
Radical prostatectomy is the most common and effective treatment for localized prostate cancer. Unfortunately, radical prostatectomy is associated with significant adverse effects, such as urinary incontinence, sexual…
- Trial name
- NCT02036684
- Testing
- Prehabilitation (PREHAB)
- Where
- 2 sites in Canada
- Volunteers
- 86 people
- Sponsor
- University of Guelph-Humber
Lymphocele After Surgical Procedure
MICHL-trial: Impact of Peritoneal Bladder Flap in RARP Patients on Lymphoceles
A two-armed prospective randomised, controlled, single-centre trial on 1080 patients with prostate cancer who underwent robot-assisted radical prostatectomy with bilateral pelvic lymph node dissection was carried out.
- Trial name
- NCT06284135
- Testing
- Michl-stitch
- Where
- Germany
- Volunteers
- 1,080 people
- Sponsor
- Martini-Klinik am UKE GmbH
Prostate Cancer
Postoperative Pain Control for Prostatectomy
The researchers propose to investigate a relatively new anesthetic procedure, in order to maximize patient comfort and minimize the use of narcotics after a radical prostatectomy.
- Trial name
- TAP (NCT00913068)
- Testing
- Transverse Abdominal Plan (TAP), standard post op pain control
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Nova Scotia Health Authority