Clinical trials: Post Prostatectomy
Prostatic Neoplasm
Early Salvage Stereotactic Radiotherapy for Biochemical Failure After RP
After radical prostatectomy, 30-60% of patients will develop recurrent disease. Salvage radiotherapy, usually at 2 Gy per fraction, is the main treatment option for these patients.
- Trial name
- esSBRT (NCT05667636)
- Testing
- salvage SBRT
- Where
- Italy
- Volunteers
- 103 people
- Sponsor
- Regina Elena Cancer Institute
Prostate Cancer
Qudratus Lumborum Block for Postoperative Pain After Endoscopic Prostatectomy.
Laparoscopic prostatectomy (LP) is characterized by substantial tissue trauma, despite its minimally -invasive approach. Although postoperative pain intensity is lower when compared to open procedures, the use of opioids is…
- Trial name
- NCT03600129
- Testing
- Qadratus Lumborum Block, 30 milliliters of 0.375% Ropivacaine, 30 milliliters of 0.9% NaCl
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Centre of Postgraduate Medical Education
Localized Prostate Cancer
Hypofractionated Post-prostatectomy Radiotherapy (HYPORT)for Localized Prostate Cancer
The aim of this trial is to compare the safety outcomes of Hypofractionated postprostatectomy radiotherapy (HYPORT) and Conventionally fractionated postprostatectomy radiotherapy(COPORT) in treating patients with localized…
- Trial name
- NCT06325995
- Testing
- Conventional radiation therapy, Hypofractionated radiation therapy
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Changhai Hospital
Prostate Adenocarcinoma
A Study of Effects of Fesoterodine in Men at High Risk for Overactive Bladder/Detrusor Overactivity Post Robotic-Assisted Lap. Prostatectomy
The investigators will assess the incidence of Overactive Bladder/Detrusor Overactivity (OAB/DO) post-operatively in patients post robotic assisted radical prostatectomy (RARP) and to investigate whether fesoterodine will alter…
- Trial name
- NCT01661166
- Testing
- Fesoterodine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Prostate Cancer, Lymphocele After Surgical Procedure
Effect of Peritoneal Fixation on Lymphocele Formation
The PerFix Trial aims to compare the use of peritoneal fixation technique to standard of care (no fixation) during robot-assisted radical prostatectomy with extended pelvic lymph node dissection (RARP + eLND) for the prevention…
- Trial name
- PerFix (NCT04853095)
- Testing
- Peritoneal fixation (PerFix), Standard of care
- Where
- Czechia
- Volunteers
- 260 people
- Sponsor
- University Hospital Olomouc
Prostate Adenocarcinoma, Recurrent Prostate Carcinoma
Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer
This phase II trial studies how well finite androgen ablation with or without abiraterone acetate and prednisone work in treating patients with prostate cancer that has come back.
- Trial name
- NCT01786265
- Testing
- Abiraterone Acetate, Bicalutamide, Degarelix
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- M.D. Anderson Cancer Center
Impotence, Prostatic Neoplasms
Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer
The purpose of this study is to determine if adding hyperbaric oxygen therapy, a therapy that delivers oxygen under slight pressure, to a drug treatment of PDE5I (such as Viagra, Levitra, Cialis)for men following surgery for…
- Trial name
- HBOT (NCT00906269)
- Testing
- Sildenafil therapy plus post-NSRRP HBO2T
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hartford Hospital
Prostate Cancer (Post Prostatectomy)
Comparative Performance of 64Copper [64Cu]-SAR-bis-PSMA vs 68Ga PSMA-11 PET CT for the Detection of Prostate Cancer Recurrence in the Setting of Biochemical Failure Following Radical Prostatectomy
The goal of this clinical trial is to compare 64Cu-SAR-bisPSMA PET/CT and 68Ga PSMA-11 PET/CT in men with biochemical failure following radical prostatectomy.
- Trial name
- Co-PSMA (NCT06907641)
- Testing
- 64Cu-SAR-bisPSMA
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- St Vincent's Hospital, Sydney
Pain
Does the TAP Block Work Better Than the TFP Block for Relieving Pain
Regional anesthetics, nerve blocks, and interfascial blocks are becoming more common in many types of surgery to help with pain after surgery.
- Trial name
- Tapblock (NCT06975735)
- Testing
- TAP Plane Block, TFP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
PROSTATECTOMY, URINARY INCONTINENCE
EFFECT ON QUALITY OF LIFE AFTER PROSTATECTOMY
Aim: This study was conducted to determine the effect of pelvic floor exercises (PTE) on urinary incontinence and quality of life (QOL) after radical prostatectomy (RP).
- Trial name
- NCT05700487
- Testing
- PELVIC FLOOR EXERCISES
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Prostate Cancer
11C Acetate Imaging Post Prostatectomy
This research is being conducted to test an imaging technique that may be able to detect small amounts of prostate cancer that can not be detected by standard imaging.
- Trial name
- NCT01602783
- Testing
- 11C Acetate Imaging
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital
Prostate Cancer
Shorter Duration Radiotherapy to Treat Prostate Cancer After Removal of the Prostate
Radiation therapy is one of the standard treatments for men with prostate cancer who have detectable levels of prostate specific antigen (PSA, a prostate cancer specific marker) after surgery.
- Trial name
- HypoFX (NCT01868386)
- Testing
- Hypofractionated therapy
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Timothy Showalter, MD
Prostate Cancer
FACBC Outcomes for Post Prostatectomy
Investigators will perform a study with 162 patients in whom there is a strong suspicion of prostate cancer that has returned to the body after having a prostatectomy.
- Trial name
- NCT01666808
- Testing
- FACBC, Radiation therapy
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Emory University
Prostate Carcinoma
Prostate Resection After Microwave Ablation (PRAMA)
This phase I trial tests the safety of magnetic resonance imaging (MRI)/ ultrasound (US) fusion guided transperineal targeted microwave ablation (TMA) before a radical prostatectomy (RP) and how well it works in treating patients…
- Trial name
- NCT06128525
- Testing
- Biospecimen Collection, Microwave Ablation, Multiparametric Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Southern California
Impaired Cognition, Quality of Life
The Assessment of the Feasibility of a Home Based Exercise Programme in the Older Patient Following Major Surgery
The primary aim of this study is to establish if it is possible for patients who have undergone major body surgery to complete a home based exercise training program and complete the assessments required to measure physical and…
- Conditions
- Impaired Cognition, Quality of Life, Surgery, Delirium
- Trial name
- POETold (NCT03064308)
- Testing
- Exercise Programme
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- University of Nottingham
Lymphocele After Surgical Procedure
Peritoneal Iliac Flap and Lymphocele Formation After Robotic Radical Prostatectomy
Lymphoceles are a potentially serious complication of radical prostatectomy (RP) with pelvic lymph node dissection. They are associated with abdominal pain, urinary tract symptoms, fever, lower extremity swelling and deep vein…
- Trial name
- NCT03567525
- Testing
- lymph node dissection using the peritoneal iliac flap approach to seal lymphatic vessels, Standard surgical approach
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Hartford Hospital
Prostate Cancer
Trial to Evaluate Radiotherapy Followed by Endocrine Therapy Vs Endocrine Therapy Alone for PSA Failure After Radical Prostatectomy
The purpose of this study is to evaluate radiotherapy followed by endocrine therapy in comparison with endocrine therapy alone for PSA failure after radical prostatectomy.
- Trial name
- NCT00138008
- Testing
- endocrine therapy, radiotherapy
- Where
- 34 sites in Japan
- Volunteers
- 200 people
- Sponsor
- Haruhiko Fukuda
Prostate Cancer
Postoperative Pain Control for Prostatectomy
The researchers propose to investigate a relatively new anesthetic procedure, in order to maximize patient comfort and minimize the use of narcotics after a radical prostatectomy.
- Trial name
- TAP (NCT00913068)
- Testing
- Transverse Abdominal Plan (TAP), standard post op pain control
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Nova Scotia Health Authority
Prostate Cancer
Radiation Therapy, Androgen Suppression, and Docetaxel in Treating Patients With High-Risk Prostate Cancer Who Have Undergone Radical Prostatectomy
RATIONALE: Specialized radiation therapy that delivers a high-dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Androgens can cause the growth of prostate cancer cells.
- Trial name
- NCT00528866
- Testing
- bicalutamide, docetaxel, flutamide
- Where
- 70 sites in United States, Canada
- Volunteers
- 80 people
- Sponsor
- Radiation Therapy Oncology Group
Prostatic Neoplasms
Genomics and Efficacy of Post-prostatectomy Salvage Radiotherapy With 'Extreme' Hypofractionation
The study aims to validate the Decipher® genomic test, in which patients with biochemical recurrence after radical prostatectomy are treated with salvage radiotherapy with extreme hypofractionation (5+ Gy/fraction).
- Trial name
- NCT06894628
- Where
- Italy
- Volunteers
- 103 people
- Sponsor
- Regina Elena Cancer Institute