Clinical trials: Post Prostatectomy
Prostatectomy, Prostate Cancer
Physical Activity Intervention in African American Men After Radical Prostatectomy
The purpose of this pilot study is to evaluate the feasibility of recruiting African American prostate cancer survivors to a 12 week physical activity intervention study of three arms (aerobics, resistance training, and usual…
- Trial name
- NCT02621684
- Testing
- Community Health Activities Model Program for Seniors (CHAMPS), Lifetime Total Physical Activity Questionnaire, Expanded Prostate Cancer Index Composite (EPIC)
- Sponsor
- Washington University School of Medicine
Prostate Cancer, Quality of Life
Functional Outcomes and QoL in Patients With High Versus Low and Intermediate Risk Prostate Cancer Treated by RARP
The Be-RALP database is Belgian prospective multicenter database governed by the Belgian cancer registry. This database investigates the status after robot assisted laparoscopic prostatectomy (RALP) in prostate cancer patients.
- Conditions
- Prostate Cancer, Quality of Life, Erectile Function, Urinary Function
- Trial name
- NCT03790995
- Testing
- Robot assisted laparoscopic prostatectomy
- Where
- 25 sites in Belgium
- Volunteers
- 9,235 people
- Sponsor
- KU Leuven
Prostate Cancer
Impact of Hormonal Therapy on Prostate Cancer Recurrence After Radical Prostatectomy
Prostate cancer is the most common cancer in men and radical prostatectomy is the most frequent treatment for this disease. Unfortunately, approximately 40% of patients will develop recurrence after surgery, requiring additional…
- Trial name
- NCT05169112
- Testing
- Lupron Depot
- Where
- 3 sites in Canada
- Volunteers
- 72 people
- Sponsor
- Ottawa Hospital Research Institute
Prostate Cancer (Post Prostatectomy)
Adjuvant Rezvilutamide Monotherapy for High-Risk Prostate Cancer After Radical Prostatectomy
Prostate cancer patients with high-risk features who undergo radical prostatectomy (RP) are at a significant risk of biochemical recurrence (BCR) and disease progression.
- Trial name
- ARMOR (NCT07711314)
- Testing
- Rezvilutamide Tablets
- Where
- China
- Volunteers
- 48 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Pain, Catheter Complications
Study Comparing Urinary Diversion (Transurethral/Suprapubic) After Radical Prostatectomy
The study aims to show the technical feasibility of the suprapubic urinary diversion after endoscopic extraperitoneal radical prostatectomy (EERPE) and has a greater comfort for the patients with at least the same catheter…
- Trial name
- NCT01465594
- Testing
- transurethral catheter after EERPE/ RALP, suprapubic catheter after EERPE /RALP
- Where
- Germany
- Volunteers
- 106 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Prostate Adenocarcinoma, Stage IIB Prostate Cancer AJCC v8
Hypofractionated Radiation Therapy for Treating Prostate Cancer High-Risk Features Following Radical Prostatectomy
This phase II trial studies how well hypofractionated radiation therapy works in treating participants with prostate cancer high-risk features following radical prostatectomy.
- Conditions
- Prostate Adenocarcinoma, Stage IIB Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8
- Trial name
- NCT03570827
- Testing
- Androgen Suppression, Hypofractionated Radiation Therapy, Quality-of-Life Assessment
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Mayo Clinic
Prostate Cancer (CRPC), Peak Expiratory Flow
Comparison of Peak Expiratory Flow Changes After Robot-Assisted Versus Open Radical Prostatectomy
This prospective, randomized controlled trial aims to compare perioperative respiratory changes in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALRP) and open radical prostatectomy (ORP).
- Trial name
- NCT07262073
- Testing
- Surgical procedure: Robot-assisted laparoscopic radical prostatectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Prostate Cancer
Radiation Therapy After Prostatectomy in Treating Patients With Stage III Prostate Cancer
Randomized phase III trial to compare treatment with or without adjuvant radiation therapy in men with stage III prostate cancer who have had radical prostatectomy and lymphadenectomy recently.
- Trial name
- NCT00394511
- Testing
- low-LET photon therapy
- Volunteers
- 408 people
- Sponsor
- National Cancer Institute (NCI)
Erectile Dysfunction Following Radical Prostatectomy, Incontinence
Penile Vibratory Stimulation in the Prevention of Sexual Dysfunction and Urinary Incontinence After Radical Prostatectomy
To investigate if post-operative penile vibration stimulation kan be used to reduce or prevent sexual dysfunction and urinary incontinence after radical prostatectomy.
- Trial name
- NCT06200987
- Testing
- Penile vibrator
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev and Gentofte Hospital
Prostatic Hyperplasia
Storage Symptom After Laser Prostatectomy
Recent literature indicated that postoperative storage symptoms after Photoselective vaporization of the prostate (PVP) or holmium laser enucleation of the prostate (HoLEP) were often reported and generally more common than after…
- Trial name
- NCT02073799
- Testing
- Laser prostatectomy (Photoselective vaporization of the prostate or Holmium laser enucleation of the prostate)
- Where
- South Korea
- Volunteers
- 486 people
- Sponsor
- Seoul National University Hospital
Prostate Cancer
Oncological and Functional Outcomes After Radical Prostatectomy for Prostate Cancer: Comparing Open With Robot-assisted Surgery
For primary surgical treatment of prostate cancer the investigators compare the classic open surgery (radical retropubic prostatectomy, RRP) versus robot-assisted laparoscopic surgery (RALP).
- Trial name
- NCT01578356
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Erectile Dysfunction
Research Evaluating an Investigational Medication for Erectile Dysfunction - Post-Prostatectomy
The objectives of this study are to evaluate the safety and efficacy of two doses of avanafil in the treatment of adult males for erectile dysfunction following bilateral nerve-sparing radical prostatectomy.
- Trial name
- NCT00895011
- Testing
- Avanafil
- Where
- 51 sites in United States
- Volunteers
- 298 people
- Sponsor
- VIVUS LLC
Genitourinary Cancer
Discharge Medication Use Post-Operatively in GU Cancer Patients
The main purpose of this research study is to determine the amount of opioids that are taken after discharge following a cystectomy, nephrectomy (partial or total), or prostatectomy surgeries via a 30-day post- discharge opioid…
- Trial name
- NCT06795087
- Testing
- Opioid Medication Disposal Education
- Where
- United States
- Volunteers
- 684 people
- Sponsor
- Wake Forest University Health Sciences
Urinary Incontinence
The Effects of Neuromuscular Electrical Stimulation in Individuals With Urinary Incontinence After Prostatectomy
The aim of this study is to investigate the effects of neuromuscular electric stimulation on urinary symptoms, quality of life, sexual function, perception of improvement and patient satisfaction in individuals with…
- Trial name
- NCT05236088
- Testing
- Neuromuscular electrical stimulation application
- Volunteers
- 50 people
- Sponsor
- Ankara Yildirim Beyazıt University
Urinary Incontinence
Trial to Assess the Efficacy of the Comfort Plug™in Preventing Urinary Incontinence (COMFORT STUDY)
Validation Study: A Prospective, Non-Randomized, Single Arm Trial to Assess the Efficacy of the Comfort Plug™ in Preventing Urinary Incontinence in Male Subjects with Post Prostatectomy Urinary Incontinence (COMFORT STUDY)
- Trial name
- NCT03605459
- Testing
- Comfort Plug™
- Where
- 4 sites in Canada
- Volunteers
- 30 people
- Sponsor
- CMX Research
Prostate Cancer
Combined Apalutamide, Radiotherapy, and LHRH Agonist in Prostate Cancer Patients After Prostatectomy
This is a multicenter, randomized, open label, phase III study comparing the efficacy and safety of apatulamide combined with concomitant prostate-bed salvage radiotherapy (SRT) and androgen deprivation therapy (ADT) versus…
- Trial name
- CARLHA-2 (NCT04181203)
- Testing
- Apalutamide, Salvage radiotherapy (SRT), Luteinising Hormone Releasing Hormone agonist (LHRHa)
- Where
- 15 sites in France
- Volunteers
- 490 people
- Sponsor
- UNICANCER
Urinary Incontinence
Effects of Action Observation Training (AOT) in the Achievement of Urinary Continence in Men After Robot-assisted Laparoscopic Prostatectomy (RALP)
Urinary incontinence (UI) is one of the most common side effects of radical prostatectomy (RP) and compromises men's quality of life.
- Trial name
- NCT05311267
- Testing
- Action observation training
- Where
- Italy
- Volunteers
- 92 people
- Sponsor
- Istituto Clinico Humanitas
Prostate Cancer
Archive Prostate. Observational Study of Patients Who Underwent Radical Prostatectomy Surgery
This is a single-center, observational, prospective study on quality of life and disease status of patients who underwent radical prostatectomy.
- Trial name
- NCT06154499
- Testing
- Radical prostatectomy
- Where
- Italy
- Volunteers
- 1,784 people
- Sponsor
- IRCCS San Raffaele
Prostate Cancer
Early Salvage Therapy for Patients With Advanced Features for Biochemical Relapse After Radical Prostatectomy for Localized Prostate Carcinoma In Correlation With Supposed Molecular-genetic Parameters of Higher Aggressiveness
The primary objective of the trial is to compare the impact and safety of delayed salvage therapy (dSRT, i.e., SRT initiated at PSA values of 0.4-0.5 ng/ml) to those of early salvage therapy (eSRT, i.e., at PSA levels of 0.2…
- Trial name
- ESTABLISH (NCT05232578)
- Testing
- Early salvage radiotherapy (eSRT), Delayed Salvage radiotherapy (dSRT)
- Volunteers
- 380 people
- Sponsor
- General University Hospital, Prague
Prostate Cancer
Early DVC Ligation and Urinary Continence Recovery After RARP
The aim of the study is to evaluate the impact of early deep venous complex ligation (eDVCL) in patients affected by clinically localized prostate cancer (PCa) undergoing robot-assisted radical prostatectomy with or without…
- Trial name
- NCT03368378
- Testing
- Early DVC ligation
- Where
- Italy
- Volunteers
- 312 people
- Sponsor
- IRCCS San Raffaele