Clinical trials: Post Pulmonary Resection
Pleural Effusion Recurrence, Pulmonary Resection
Evaluation of Fluid Output Threshold for Safe Chest Tube Removal - A Potential Way to Decrease Length of Stay in Hospital and to Improve Postoperative Care After Lung Surgery?
Previous studies have shown that the removal of the chest tube after lung surgery significantly improves pain symptoms and lung function.
- Conditions
- Pleural Effusion Recurrence, Pulmonary Resection, Chest Tube Management
- Trial name
- NCT03093610
- Testing
- Traditional, Test
- Where
- Switzerland
- Volunteers
- 337 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Video-assisted Thoracic Surgery, Postoperative Atelectasis
Optimal Level of PEEP in Protective One-lung Ventilation
Protective ventilation strategy has been widely applied in the field of thoracic surgery requiring one-lung ventilation to reduce postoperative pulmonary complications.
- Conditions
- Video-assisted Thoracic Surgery, Postoperative Atelectasis, Positive End-expiratory Pressure
- Trial name
- NCT03856918
- Testing
- PEEP 3 cm of water, PEEP 6 cm of water, PEEP 9 cm of water
- Where
- South Korea
- Volunteers
- 142 people
- Sponsor
- Seoul National University Hospital
Lung Cancer, Lung Diseases
Outcomes Following Omission of Daily Routine Chest Radiographs Following Pulmonary Resection
Currently, it is the standard of care practice to perform daily routine CXR when a chest tube is in situ following pulmonary resection.
- Conditions
- Lung Cancer, Lung Diseases, Lung Cancer, Nonsmall Cell, Surgery
- Trial name
- NCT03704870
- Testing
- Chest Xray, No daily chest xray
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Atrial Fibrillation, Lung Cancer
Study of Amiodarone Given Before Lung Surgery to Prevent Atrial Fibrillation After Lung Resection
Atrial fibrillation is a very common complication of pulmonary resection. Patients who develop atrial fibrillation require additional treatment and are more likely to stay in the hospital for longer period of time increasing the…
- Trial name
- NCT00300495
- Testing
- Amiodarone, Control arm, standard care
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Beth Israel Deaconess Medical Center
Air Leak From Lung
Hemopatch Compared to TachoSil in Postoperative Air Leak Duration After Pulmonary Resection
This study is a randomized, controlled study, with the primary objective to demonstrate non-inferiority of Hemopatch compared to TachoSil in postoperative air leak duration after pulmonary resection, and with the secondary…
- Trial name
- NCT03450265
- Testing
- Hemopatch, Tachosil
- Where
- 14 sites in Italy, Spain
- Volunteers
- 279 people
- Sponsor
- Baxter Healthcare Corporation
Lobectomy
Tegileridine Combined With Intercostal Nerve Block After Thoracoscopic Lung Resection
Combining tegileridine PCIA with ICNB targeting peripheral nerves, may constitute an ideal analgesic model with complementary advantages.
- Trial name
- NCT07386626
- Testing
- Tegileridine, Intercostal Nerve Block, Sufentanil
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Tongji Hospital
LUNG DISEASES
SEALLS (Sealing Evaluation of Air Leaks After Lung Surgery) Trial Using HEMOPATCH
The primary objective is to assess the efficacy and safety of HEMOPATCH™ Sealing Hemostat in reducing the incidence and duration of air leaks after lung resection compared to standard techniques.
- Trial name
- NCT02668978
- Testing
- Hemopatch™ Sealing Hemostat, Standard surgical technique
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- Quirón Madrid University Hospital
Urinary Retention
Post-operative Urinary Retention (POUR) Following Thoracic Surgery
Inability to urinate a common complication that happens to many patients after a surgery, especially in men over 60 years of age who undergo surgery on their chest.
- Trial name
- POUR (NCT03609580)
- Testing
- Tamsulosin - 1 week, Tamsulosin - 3 days
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health
Right Ventricular Dysfunction, Pneumonectomy; Status
Right Ventricle Function After Major Right Lung Resection
Major lung resection is associated with high post-operative morbidity and mortality and significant long-term decreased functional capacity, especially due to cardiorespiratory complications.
- Trial name
- RIVER (NCT04167241)
- Testing
- Echocardiography
- Volunteers
- 50 people
- Sponsor
- Humanitas Clinical and Research Center
Tele-pulmonary Rehabilitation, Lung Cancer
The Effectiveness of Tele-Pulmonary Rehabilitation After Lung Resection
As a result of the review in the literature, no study was found in which tele-pulmonary rehabilitation was applied after physiotherapist-supervised lung resection via video conferencing.
- Conditions
- Tele-pulmonary Rehabilitation, Lung Cancer, Lung Resection
- Trial name
- NCT05794607
- Testing
- Rehabilitation group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Halime Sinem Barutçu
Lung Cancer (NSCLC)
Snakehead Fish Extract and Curcumin Co-Supplementation in Advanced Lung Cancer on Inflammation, Nutritional Status, and Quality of Life
Background: Patients with advanced lung cancer receiving systemic therapy often experience nutritional decline, systemic inflammation, and impaired quality of life.
- Trial name
- BMI (NCT07906626)
- Testing
- Snakehead Fish Extract and Curcumin
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Sumatera Utara
Adults Patients Undergoing Major Lung Resection in the Context of Lung Cancer
Predictive Value of a Preliminary Swallowing Test Compared to Postoperative Nasofibroscopy to Identify Vocal Cord Paralysis After Pulmonary Resection
The literature describes recurrent nerve damage during thoracic surgery as a fairly complication (5 to 31% of patients). This nerve damage leads to paresis or paralysis of the ipsilateral vocal cord.
- Trial name
- SwaLO (NCT05193240)
- Testing
- preliminary swallowing test
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Rouen
Lung Cancer, Thoracic Surgery
Epidural Anesthesia-analgesia and Long-term Survival After Lung Cancer Surgery
Available studies suggest that regional anesthesia-analgesia may decrease the occurrence of recurrence/metastasis in patients after cancer surgery. However, evidences from prospective studies are still lacking.
- Conditions
- Lung Cancer, Thoracic Surgery, Anesthesia, Epidural, Neoplasm Recurrence, Local
- Trial name
- NCT02801409
- Testing
- General anesthesia alone, Combined epidural-general anesthesia
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University First Hospital
Elective, Lung Resection
Cerebral Oxygenation After Lung Resection
The investigators hypothesize that the lung resection would be associated with lower jugular bulb oxygen saturation in patients with severe pulmonary dysfunction than in patients with healthy lung functions.
- Conditions
- Elective, Lung Resection, Surgery
- Trial name
- NCT01183871
- Testing
- Monitoring of cerebral oxygenation
- Where
- Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- King Faisal University
Nonsmall Cell Lung Cancer
Study of Durvalumab + Tremelimumab in NSCLC Patients After Adjuvant Treatment
The purpose of this study is to determine whether it is feasible and safe to give research participants investigational treatment with durvalumab and tremelimumab after they have completed standard treatment for NSCLC and once…
- Trial name
- NCT04625699
- Testing
- Durvalumab, Tremelimumab
- Sponsor
- Catherine Shu
Resectable Lung Non-Small Cell Carcinoma
Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer
This clinical trial tests proton beam radiation therapy in patients with non-small cell lung cancer who have undergone surgical resection and have lymph nodes involving the middle of the chest.
- Trial name
- NCT06008730
- Testing
- Biospecimen Collection, Proton Beam Radiation Therapy, Radiology, Treatment Planning
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Lung Neoplasm, Lung Cancer
Lung Ultrasound to Assess Aeration Loss After Lung Resection Surgery
The purpose of this prospective observational study is to assess perioperative changes in lung aeration after lung resection surgery using lung ultrasound, and to explore their relationship with oxygenation, inflammatory…
- Conditions
- Lung Neoplasm, Lung Cancer, Lung Resection Surgery, Thoracic Surgery
- Trial name
- THORUS (NCT04677309)
- Testing
- Perioperative lung ultrasound assessment
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Ana Broseta Lleó
Lung Cancer
Osimertinib to Suppress the Progression of GGN(EGFR Mutation-positive)
This study designed to assess the efficacy of osimertinib (80 mg, orally, once daily) to suppress the progression of remaining GGN(s) in other lobes following surgical resection for actionable EGFR mutation-positive stage I lung…
- Trial name
- NCT04591002
- Testing
- Osimertinib 80 MG
- Where
- 2 sites in South Korea
- Volunteers
- 43 people
- Sponsor
- Samsung Medical Center
Non-small Cell Lung Cancer, Lung Cancer
3D Virtual Resection for Predicting Lung Function in VATS
This study aims to validate a novel preoperative assessment strategy using three-dimensional (3-D) computed tomography (CT) reconstruction and virtual resection simulation.
- Conditions
- Non-small Cell Lung Cancer, Lung Cancer, Lung Neoplasms
- Trial name
- NCT07436598
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Lung Cancer
Removal of Lung Nodules After Being Marked With a Microcoil
The objective of this study is to determine if subcentimetre pulmonary nodules can be accurately and safely excised by endoscopic stapling devices after they have been localized using CT and marked with a microcoil device.
- Trial name
- NCT00323089
- Testing
- microcoil insertion and excision
- Where
- Canada
- Volunteers
- 151 people
- Sponsor
- University of British Columbia