Clinical trials: Post Stroke
Aphasia, Stroke
Brain-based Understanding of Individual Language Differences After Stroke
Strokes often cause a loss of communication ability, referred to as aphasia, as well as cognitive difficulties. Each stroke survivor has a unique pattern of strengths and weaknesses in communication and cognition, and a unique…
- Conditions
- Aphasia, Stroke, Alexia
- Trial name
- BUILD (NCT04991519)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Motor Activity
Variability of Healthy People and People After Stroke Results in the Box and Block Test
Main aim of the study is to find out how many attempts of each subtest in the Box and Block Test should be done in clinical practice during testing people after stroke who are 20-64 years old.
- Trial name
- NCT05925231
- Testing
- Box and Block Test
- Where
- 2 sites in Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Traumatic Brain Injury, Stroke
Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury
Background: Previous research has shown that certain parts of the brain are involved in voluntarily stopping an ongoing motor response (movement); however, it is not known whether this same network is also involved in suppressing…
- Conditions
- Traumatic Brain Injury, Stroke, Headache, PTSD
- Trial name
- NCT01194661
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Perceptual-motor Interaction to Improve Bimanual Coordination After Stroke
Significant difficulty in incorporating the weaker arm in daily activities after stroke is, in part, driven by difficulty in engaging both arms interactively in a coordinated manner.
- Trial name
- Bimanual (NCT03755076)
- Testing
- Perceptual cuing
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Ischemic Stroke, Stroke
A Functional MRI Study: Assessing Brain Function in Post Stoke Patients
This is a prospective, single center, observational clinical study containing two cohorts the healthy cohort and post stroke cohort. A total of 13 subjects will be enrolled.
- Conditions
- Ischemic Stroke, Stroke, Acute Ischemic Stroke
- Trial name
- NCT06573840
- Testing
- NeuroGlove
- Volunteers
- healthy volunteers welcome
- Sponsor
- NeuroGlove LLC
Stroke
Stroke Patients Receiving Chiropractic Care Post-rehabilitation
The Life University Center for Chiropractic Research is conducting a research study to better understand how 12-weeks of chiropractic care differentially affects the post-rehabilitation brain electrical patterns and body movement…
- Trial name
- NCT05027178
- Testing
- Chiropractic Care
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Life University
Ischemic Stroke
Safety, Tolerability and Pharmacokinetic Characteristics Evaluation on DA414
The purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK) and Food Effects of DA414 Granules in Chinese healthy subjects with single and multiple doses.
- Trial name
- DA414 (NCT06525168)
- Testing
- DA414 Granules
- Where
- China
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Chendu DIAO Nine Hong Pharmaceutical Factory
Stroke
Efficacy of an Interactive Web-Based Home Therapy Program After Stroke
This is an online study that involves assessment and training of arm function at home. Stroke is the leading cause of disability worldwide.
- Trial name
- STRONG (NCT03484182)
- Testing
- Web-based Home Exercise Program, Standard Home Exercise Program
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Oropharyngeal Dysphagia, Stroke
The Utility of Cerebellar Transcranial Magnetic Stimulation in the Neurorehabilitation of Dysphagia After Stroke
The study is designed to explore the effectiveness of non-invasive cerebellar stimulation to enhance motor plasticity in the cortex after stroke.
- Trial name
- NCT03274947
- Testing
- Cerebellar TMS
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Acute Ischemic Stroke
The Effect and Mechanism of wCST-LL Based Precision Rehabilitation Nursing on Motor Dysfunction After Acute Stroke
Ischemic stroke is the main cause of disability in the world. More than 70% of stroke patients show various degrees of neural function impairment.
- Trial name
- NCT03702452
- Testing
- functional rehabilitation nursing program, control group
- Where
- China
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke
Efficacy of Robot-Assisted Rehabilitation of Hand Paralysis After Stroke
Among robotic devices, Gloreha, with its compliant mechanical transmission, may represent an easily applied innovative solution to rehabilitation, because the hand can perform grasp and release activities wearing the device by…
- Trial name
- NCT02711787
- Testing
- Experimental group, Control group, traditional rehabilitation
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Cerebral Infarction
TSK (Tryptophan - Serotonin - Kynurenine) Biomarkers Assessment in Stroke
Single-center, prospective, descriptive and biomedical research with controls, without health product. Depression is the second risk factor for stroke as tobacco smoking following hypertension.
- Trial name
- NCT02963545
- Testing
- Usual care patients in neurology department, blood and urines sampling, Psychiatric evaluation
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Versailles Hospital
Stroke, Acute, Neuroprotection
Effectiveness and Biological Mechanism of Direct Ischemic Post-conditioning for Acute Stroke Patients Due to Large Vessel Occlusion
The goal of this clinical trial is to determine if direct ischemic post-conditioning (IPostC) can alleviate ischemic-reperfusion injury (I/R) in patients who have undergone endovascular thrombectomy (EVT).
- Conditions
- Stroke, Acute, Neuroprotection, Ischemic Conditioning
- Trial name
- NCT06545734
- Testing
- Direct Ischemic Post-conditioning, Endovascular therapy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tianjin Huanhu Hospital
Stroke
Brain Plasticity Mapping Post-stroke
The investigators believe that the initial cerebral connectivity as well as its evolution immediate post-stroke could be correlated to the amount of motor recovery.
- Trial name
- MAPPY (NCT03223571)
- Testing
- Motor rehabilitation training
- Where
- France
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Stroke
Effects of Aerobic Exercise on the Cerebral Arterial System, Cognitive, and Motor Function in Post-stroke Patients.
Background: Stroke is the second leading cause of death and disability worldwide and in Hong Kong, 6.2% of all registered deaths in 2020 were due to cerebrovascular disease.
- Trial name
- NCT05706168
- Testing
- treadmill exercise, Cycle ergometer exercise
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Walking, Difficulty
Turning Dysfunction After Stroke: Assessment and Intervention
The study aims to investigate the 1) differences between stroke patients and healthy controls in time, steps, angular velocity, stepping patterns, electromyographic responses during turning, and the association of turning to…
- Conditions
- Stroke, Walking, Difficulty, Balancing Interference
- Trial name
- NCT04668573
- Testing
- Trunk exercise
- Where
- Taiwan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Stroke
The Changes of Masticatory / Swallowing Functions and Oropharyngeal Muscle Mass on Sonography After Comprehensive Swallowing Training and Tongue - Pressure Resistance Training in Stroke Patients With Dysphagia
The aims of this study are: 1. Comparing the ultrasound imaging performance of swallowing and chewing function, tongue pressure and oropharyngeal muscle thickness in stroke patients with different levels of swallowing function 2.
- Trial name
- NCT06269718
- Testing
- swallowing therapy, IOPI therapy
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Exploring New Approaches in Reaching Behavior Post Stroke
After 4 weeks of training the hypothesis that the more natural training program would yield greater functional changes was proven correct.
- Trial name
- NCT00844870
- Testing
- stabilization training, auditory training group
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of the Sciences in Philadelphia
Stroke
Mechanisms of Neuromuscular Fatigue Post Stroke
While baseline weakness is clearly an important factor that contributes to disability post stroke, neuromuscular fatigue (the acute reduction in force production) of the paretic musculature likely compounds strength deficits and…
- Trial name
- NCT01688570
- Testing
- duloxetine, Cyproheptadine
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Stroke
Relationship of Proprioception, Reaction Time and the Gait and Balance Parameters After Stroke
The aim of this observational study is to analyze how impaired proprioception affects the gait, reaction time, balance and functioning of stroke patients.
- Trial name
- NCT06187974
- Testing
- observation
- Where
- Poland
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Rzeszow