Clinical trials: Post Stroke
Aphasia Following Cerebral Infarction
Intensive Comprehensive Aphasia Programme for People With Post-Stroke Aphasia
Research question Does participation in an Intensive Comprehensive Aphasia Programme produce a meaningful change in the communication of people with aphasia, their quality of life and that of their carers? Background Aphasia is a…
- Trial name
- RCT of an ICAP (NCT07386652)
- Testing
- ICAP, Standard Care (in control arm)
- Where
- United Kingdom
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University College, London
Stroke, Aphasia
Links Between Motor Abilities and Language Ability Deficits in Patients With Post-stroke Aphasia
Aphasia is a language disorder that affects oral and written expression and/or comprehension. It's one of the most disabling consequence of stroke.
- Trial name
- MOTOLANG-AVC (NCT05776368)
- Testing
- Syntactic comprehension battery (BCS), Montreal Cognitive Assessment (MOCA), Purdue Pegboard Test
- Where
- 3 sites in France
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Stroke Gait Rehabilitation
Optimizing Gait Rehabilitation After Stroke
Following a cerebrovascular accident (CVA, also known as a stroke), hemiparesis occurs on the side opposite to the brain injury. This can lead to problems with walking and balance, as well as with arm movements whilst walking.
- Trial name
- NMC (NCT07798388)
- Testing
- VR-feedback application
- Where
- 3 sites in Belgium
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Stroke
Cortical Ischemic Stroke and Serotonin
In this study the investigators want to test the hypotheses that, serotonergic neuromodulation increases perilesional neuroplasticity, leading to improved behavioural outcomes through a more efficient allocation of functional…
- Trial name
- CISS (NCT02865642)
- Testing
- Serotonin Uptake Inhibitors
- Where
- 2 sites in Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Stroke
Multisite Transcranial Direct Current Stimulation to Promote Hand Function Recovery After Stroke
A novel multisite high definition tDCS (HD-tDCS) in healthy people showed that such network-targeted stimulation could enhance motor excitability beyond traditional stimulation which targeting only one region.
- Trial name
- NCT05638464
- Testing
- multisite HD-tDCS EMG-driven robot hand
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Chronic Stroke Patients
Effect of Transcutaneous Auricular Stimulation of the Vagus Nerve on Functional Connectivity in the Brain at Rest
The goal of this clinical trial is to study the effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on resting-state brain functional connectivity.
- Trial name
- COVAGNIRS (NCT07282106)
- Testing
- Active taVNS arm
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Clinique Les Trois Soleils
Stroke
Upper Limb Function and Visuospatial Exploration After Stroke
This project is a cross-sectional, observational mono-center study with prospective data collecting. This study aims to further explore quality of upper limb movement in relation to characteristics of visuospatial exploration in…
- Trial name
- NCT03135093
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Zurich
HR Vaiability, Aerobic Physical Fitness,Blood Pressure, Blood Sugar Level, Blood HDL, LDL
Aerobic Exercise Training & the Autonomic System In Patients After Myocardial Infarction or Stroke
The purpose of this study is to examine the effect of Aerobic Physical Activity on the function of the Autonomic System in patients after Myocardial Infarction or Stroke.
- Trial name
- NCT00259948
- Testing
- Aerobic exercise training
- Where
- Israel
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Stroke
Characterizing the Neural Bases of Motivational Disorders After Stroke
The aim of the study is to quantify elementary mechanisms of motivation, with innovative tools adapted to clinical settings, in healthy subjects, and in stroke patients.
- Trial name
- MOTI-stroke (NCT03741140)
- Testing
- Motivation tests
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Stroke
Increasing the Repertoire of Intermuscular Co-ordination Post Stroke Through EMG-Guided Human-Machine Interaction
The purposes of this study include: 1. - To identify whether features of aberrant intermuscular coordination patterns can be used to predict motor impairment after stroke. 2.
- Trial name
- NICE (NCT06523335)
- Testing
- Neuromuscular coordination-guided rehabilitative training, Force strengthening-guided rehabilitative training
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Houston
Motor Learning, Aging
OPTIMAL Motor Learning in Table Tennis: A fNIRS Study
This study investigates how OPTIMAL theory influences table tennis backhand learning in young, healthy older, and mild cognitively impaired older adults.
- Conditions
- Motor Learning, Aging, Coginitive Dysfunction
- Trial name
- NCT07914608
- Testing
- OPTIMAL theory-based Instruction, Conventional Instruction (Control)
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Post-stroke Dementia, Vascular Mild Cognitive Impairment
The Aging Brain and Cognition: Contribution of Vascular Injury, Amyloid Plaque and Tau Protein to Cognitive Dysfunction After Stroke
Stroke can lead to signficiant neurological deficits, and about one-third of stroke patients will be diagnosed of vascular mild cognitive impairment or post-stroke dementia.
- Trial name
- NCT04588649
- Testing
- THK-5351, AV-45
- Where
- Taiwan
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Stroke, Ischemic
Efficacy of REMO Training for Hand Motor Recovery After Stroke
Upper limb motor impairment is one of the most common sequelae after stroke. Indeed, the recovery of upper limb sensory-motor functions remains one of the most important goals in stroke rehabilitation.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke Sequelae
- Trial name
- REMO (NCT05815368)
- Testing
- REMO, Task-Oriented Training
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Depression, Stroke
Feasibility of the Post-Stroke Depression-toolkit
Rationale: Depression is a frequent complication after a stroke. In stroke guidelines several recommendations focus on early screening, and treatment off depression after stroke.
- Trial name
- NCT03500250
- Testing
- Post-Stroke Depression toolkit
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences Utrecht
Stroke, Acute
VNS-supplemented Motor Retraining After Stroke
The goal of this study is to learn more about the connections between the brain, spinal cord, and muscles and how these connections can be strengthened after neurological injury.
- Trial name
- NCT04088578
- Testing
- Training, Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Stroke, Quality of Life
Effectiveness of a Home-based Ergonomic Intervention Program in Caregivers of Chronic Post-stroke Patients
The objective of the present study is to evaluate the effectiveness of two home-based ergonomic intervention programs compared to a control group on the quality of life of caregivers of post-stroke patients
- Trial name
- NCT03284580
- Testing
- Ergonomic intervention, Postural plus kinesiotherapy intervention program, Control or conservative intervention
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Healthy, Stroke
The Influence of Cortical Lateralization on Selective Motor Control of the Arm Swing During Independent Walking After Stroke.
The upper limbs play an essential role for safe and efficient walking in healthy persons and persons post-stroke. Nevertheless, in current post-stroke gait rehabilitation (research) the upper limbs are barely targeted.
- Trial name
- NCT06442579
- Testing
- Walking on a treadmill
- Where
- 2 sites in Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Stroke
Operant Conditioning for Rehabilitation After Stroke
The purposes of this study include: 1. To test if multiple upper extremity muscles represented within a discrete primary motor cortex site reflect existing muscle synergies after stroke. 2.
- Trial name
- NCT05020080
- Testing
- Operant conditioning of motor evoked potentials
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Houston
Multiple Sclerosis, Stroke
An Assistive Powered Wheelchair: Stage 2 Trial
Preliminary evaluation of an obstacle alerting system to enhance the user's independent mobility by improving their confidence to drive and their safety in driving a powered wheelchair.
- Conditions
- Multiple Sclerosis, Stroke, Cystic Fibrosis, Motor Neurone Disease
- Trial name
- EDUCAT (NCT05292690)
- Testing
- Powered Wheelchair Obstacle Alerting System
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Stroke, Control Condition
Vision and Proprioception Evaluation With Robotics After Stroke
Stroke is highly prevalent in Canada and can lead to profound upper limb impairments in motor and sensory function, as well and vision.
- Trial name
- VIPERS (NCT07254949)
- Where
- 2 sites in Canada
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Dr. Sean Dukelow