Clinical trials: Post Stroke, open to volunteers
Stroke
Correlation Between Clinical Neurological Biomarkers and Rehabilitation Outcome
Our study purpose is to evaluate the predictive power of various clinical, neurophysiological, and neuroimaging biomarkers-acquired and analyzed using advanced and integrated techniques-on motor functional recovery and disability…
- Trial name
- PREVICTUS (NCT06805929)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS San Raffaele Roma
Stroke, Stroke Sequelae
Efficacy of Rehabilitation Using Action Observation and Muscle Stimulation in Post-stroke Patients.
Stroke is the third most common cause of disability worldwide and leads to upper limb motor disease in more than half of people affected.
- Trial name
- OTHELLO (NCT06055569)
- Testing
- Rehabilitation protocol: AOT+NMES, Rehabilitation protocol: Action Observation Therapy (AOT), Observation of motor-neutral stimuli (MNO)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Cerebrovascular Accident, Post-polio Syndrome
Nomad P-KAFO Study
The goal of this clinical trial is to evaluate the impact of using the Nomad powered KAFO in people who have had a musculoskeletal or neurological injury that has affected their ability to walk.
- Conditions
- Cerebrovascular Accident, Post-polio Syndrome, Spinal Cord Injuries, Multiple Sclerosis
- Trial name
- NCT05644522
- Testing
- Indego Nomad® Powered Knee-Ankle-Foot Orthosis (P-KAFO) (Parker Hannifin Corp., Cleveland, OH)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Stroke Rehabilitation
Comparison Between LL Sesorimotor Training and WBB Therapy on PS, DB and FOF in Post Stroke Patients
Stroke is a neurological disorder causing 70-80 percent deaths in the low income and developing countries. Patients commonly present with common impairments associated with balance, proprioception, poor gait, speech impairment…
- Trial name
- NCT07642154
- Testing
- Sensorimotor Training, Whole Body Vibration Training
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Cerebral Infarction, Thrombolysis
Early Low-dose ASpirin Use After Intravenous Thrombolysis for Acute Ischemic Cerebral Infarction（ELASTIC）
This study evaluates whether early administration of low-dose aspirin (100mg) at 2 hours post-intravenous thrombolysis, compared to the standard timing of 24 hours, improves functional outcomes in patients with acute ischemic…
- Trial name
- ELASTIC (NCT07563673)
- Testing
- Aspirin (Early, 2h), Aspirin (Standard, 24h)
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Beijing Chao Yang Hospital
Stroke, Dementia
Taiwan Post-Stroke Disability Study
Stroke remains a major health issue in Taiwan, being the fourth leading cause of death and the top cause of disability. While past research has focused on functional outcomes at three months post-stroke, stroke can cause a range…
- Conditions
- Stroke, Dementia, Epilepsy, Depression
- Trial name
- T-PODS (NCT06772194)
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
Stroke Not Otherwise Specified
More Steps Towards an Active Life After Stroke - ActForStroke
The main goal of this quasi-experimental study is to prevent the negative consequences of mobility impairments after stroke. These include recurrent strokes, general deconditioning, and overweight on the physical side, and…
- Trial name
- ActForStroke (NCT06715566)
- Testing
- ActForStroke, Standard care
- Where
- 10 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Ischemic Stroke, Diabete Mellitus
DPP4 Inhibitor Intervention on Post-stroke Cognitive Impairment in Ischemic Stroke Patients With Type 2 Diabetes
Post-stroke cognitive impairment (PSCI) increases the risk of disability and mortality in stroke patients, thereby exacerbating the disease burden of stroke.
- Trial name
- NCT07241897
- Testing
- Sentagliptin Phosphate - single dose
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Acquired Brain Injury (Including Stroke)
Testing a Group Memory Training Program for People With Brain Injuries
The purpose of this study is to assess the feasibility, acceptability, and effectiveness of a 6-week group-based memory training program for individuals experiencing memory problems after acquired brain injury (ABI).
- Trial name
- NCT06800040
- Testing
- Memory training
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- University Hospital of North Norway
Stroke, Muscle Spasticity
SIRS-ESWT Trial: Shoulder Internal Rotator Spasticity Trial Treated With Extracorporeal Shock Wave Therapy Trial
Extracorporeal shock wave therapy (ESWT) has shown potential in reducing post-stroke limb spasticity. This study aims to evaluate the efficacy of focused ESWT on shoulder internal rotator spasticity in post-stroke patients.
- Trial name
- NCT06674785
- Testing
- focused extracorporeal shock wave therapy (ESWT)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Basilar Artery Occlusion
Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke
Patients presenting to the emergency department with an acute ischemic stroke due to basilar artery occlusion within 24 hours of stroke onset will be assessed to determine their eligibility for randomization into the trial.
- Trial name
- POST-ETERNAL (NCT05105633)
- Testing
- Tenecteplase, Standard Care (which may include intravenous Alteplase)
- Where
- 17 sites in Australia, Brazil and 1 more
- Volunteers
- 688 people
- Sponsor
- University of Melbourne
Acute Ischemic Stroke
Hyperbaric Oxygen After Stroke Thrombectomy: A Multicenter Randomized Trial on Safety and Efficacy
1. The goal of this clinical trial is to evaluate the efficacy and safety of hyperbaric oxygen (HBO)in stroke patients after endovascular treatment 2.
- Trial name
- NOTICE-1 (NCT07049692)
- Testing
- Hyperbaric Oxygen Therapy, Conventional therapy group
- Where
- 2 sites in China
- Volunteers
- 424 people
- Sponsor
- Beijing Chao Yang Hospital
Stroke
Safety and Efficacy of NeuroTechR3 System for Upper Extremity Recovery After Stroke
This research aims to understand the feasibility and effectiveness of using the NeuroTechR3 System to improve upper extremity function after stroke.
- Trial name
- R3 (NCT07769281)
- Testing
- NeuroTechR3 Computer Rehabilitation System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brooks Rehabilitation
Stroke
Home-Based Functional Electrical Stimulation for Lower Limb Rehabilitation in Stroke Patients.
This assessor-blinded, randomized, parallel-group feasibility trial will evaluate the feasibility and preliminary effectiveness of a home-based Functional Electrical Stimulation (FES) system for lower-limb rehabilitation in…
- Trial name
- FES (NCT07785700)
- Testing
- Functional Electrical Stimulation (FES), Standard Rehabilitation
- Where
- 3 sites in India
- Volunteers
- 70 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Stroke, CVA (Cerebrovascular Accident)
Cognition and Motor Learning Post-stroke
This project seeks to determine how post-stroke cognitive impairment moderates motor learning during walking in older adults with chronic stroke and identify brain structural markers that mediate this relationship.
- Trial name
- NCT04829071
- Testing
- Explicit motor learning, Implicit motor learning
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Southern California
Stroke, Cognition
Magnesium and Cognition After Stroke
Cognitive impairments such as memory impairments, word-finding difficulties, compromised orientation and perception are often observed in stroke patients.
- Conditions
- Stroke, Cognition, Magnesium, Neurologic Disorder
- Trial name
- NCT05132517
- Testing
- Kölner Neuropsychologische Screening für Schlaganfall-Patienten
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Stroke, Stroke, Acute
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage.
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- VERIFY (NCT05338697)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- 45 sites in United States
- Volunteers
- 657 people
- Sponsor
- Yale University
Ischemic Stroke, Post-stroke Dysphagia
EEG Feedback-Based Vagus Nerve Stimulation for Post-Stroke Dysphagia
The goal of this clinical trial is to learn if electroencephalogram (EEG) biofeedback-guided transcutaneous auricular vagus nerve stimulation (taVNS) works to treat swallowing difficulties (dysphagia) in adults after a stroke.
- Conditions
- Ischemic Stroke, Post-stroke Dysphagia, Swallowing Disorders
- Trial name
- NCT07894315
- Testing
- EEG Biofeedback-Guided taVNS, Conventional taVNS
- Where
- 6 sites in China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Stroke, Dysphagia
Effects of CTAR and a Swallowing Pressure Ball in Older Stroke Adults
This study aims to investigate the effectiveness of resistance swallowing rehabilitation using Chin Tuck Against Resistance (CTAR) exercises combined with an innovative swallowing pressure ball in improving swallowing function…
- Conditions
- Stroke, Dysphagia, Post-Stroke Dysphagia
- Trial name
- NCT07620210
- Testing
- Innovative Swallowing Pressure Measurement Ball Combined With CTAR Training, Conventional Swallowing Rehabilitation
- Where
- Taiwan
- Volunteers
- 132 people
- Sponsor
- Chimei Medical Center
Ischemic Stroke
Transcranial Focused Ultrasound Neuromodulation for Post-Stroke Motor Dysfunction
This study aims to evaluate how transcranial focused ultrasound (tFUS) technology can promote neural network remodeling and functional recovery after stroke.
- Trial name
- NCT07637825
- Testing
- Transcranial Focused Ultrasound Neuromodulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jiangsu Taizhou People's Hospital