Clinical trials: Post Stroke Upper Limb Spasticity
Muscle Spasticity
Meditoxin® Treatment in Patients With Post Stroke Upper Limb Spasticity
Botulinum Toxin for the Treatment of Post Stroke Upper Limb Spasticity.
- Trial name
- NCT02757404
- Testing
- Ultrasonography guidance injection of Meditoxin®., Electrical stimulation guidance injection of Meditoxin®., Manual needle placement injection of Meditoxin®.
- Volunteers
- 59 people
- Sponsor
- Medy-Tox
Spasticity, Post-Stroke
A Phase III Study to Evaluate the Efficacy and Safety of GSK1358820 in Subjects With Post-stroke Upper Limb Spasticity
Botulinum toxin A (GSK1358820) is a sterile, purified type A botulinum neurotoxin complex. In Japan, 240 units of botulinum toxin A are approved as a maximum dose per administration for upper limb spasticity.
- Trial name
- NCT03261167
- Testing
- Botulinum toxin A (GSK1358820)
- Where
- 38 sites in Japan
- Volunteers
- 124 people
- Sponsor
- GlaxoSmithKline
Stroke
Morphological Characteristics of the Upper and Lower Extremities Using Ultrasound Examination After Stroke.
Introduction A large number of stroke patients develop spasticity in the upper and lower extremities, which is one of the clinical signs of damage to motor neuron 1, causing abnormal postures and movement patterns due to motor…
- Trial name
- Spasticity (NCT07156760)
- Testing
- Ultrasound diagnostics
- Where
- 2 sites in Chile
- Volunteers
- 80 people
- Sponsor
- Universidad de La Frontera
Stroke
Electrical Stimulation After Botulinum Toxin Injections to the Upper Extremity
The purpose of this study is to investigate the effectiveness of using electrical stimulation to improve upper extremity function in stroke survivors who receive botulinum toxin injections for spasticity.
- Trial name
- NCT04217187
- Testing
- Neuromuscular Electrical Stimulation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Texas Woman's University
Spasticity
MEDITOXIN® Versus BOTOX® in the Treatment of Post-stroke Spasticity of the Upper Limb Spasticity
This study is a randomized, double blind, multi-center, active drug controlled, phase III clinical trial to compare the efficacy and safety of MEDITOXIN® versus BOTOX® in treatment of post stroke upper limb(wrist, finger, thumb)…
- Trial name
- NCT01313767
- Testing
- Botulinum toxin type A
- Where
- South Korea
- Volunteers
- 196 people
- Sponsor
- Medy-Tox
Spasticity, Post-Stroke
A Multicenter, Open-label, Single Dose Study of the Safety and Efficacy of GSK1358820 (Botulinum Toxin Type A) in Chinese Subjects With Post-stroke Focal Upper Limb Spasticity
This trial is a multicenter, open-label study to evaluate the safety and efficacy of GSK1358820 for treatment in post-stroke subjects with focal wrist, finger and in some cases, thumb spasticity.
- Trial name
- NCT01205451
- Testing
- Botulinum toxin type A
- Where
- 13 sites in China
- Volunteers
- 109 people
- Sponsor
- GlaxoSmithKline
Chronic Stroke
Repetitive Transcranial Magnetic Stimulation Associated With Physical Therapy to Reduce Upper Limb Spasticity in Post Stroke Patients
In this study, it is being investigated if the association between high frequency repetitive transcranial magnetic stimulation associated with motor physical therapy reduces spasticity, increases upper limb motor function, and…
- Trial name
- NCT03481179
- Testing
- TMS, Physical therapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Stroke, Spasticity as Sequela of Stroke
Radial Extracorporeal Shock Wave Therapy as an Adjunct to Botulinum Toxin Type A for Post-Stroke Lower Limb Spasticity (SOLUTION)
The goal of this pilot clinical trial is to determine whether radial extracorporeal shock wave therapy (rESWT), when used as an adjunct to ultrasound-guided botulinum toxin type A (BoNT-A) injections, can enhance the therapeutic…
- Conditions
- Stroke, Spasticity as Sequela of Stroke, Lower Limb Spasticity, Upper Motor Neuron Syndrome
- Trial name
- SOLUTION (NCT07875868)
- Testing
- Radial shock Wave therapy (3000 pulses, 5 Hz, 2.5 bar)., Ultrasound-guided abobotulinumtoxin A
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Parc de Salut Mar
Stroke, Upper Limb Spasticity
Study to Assess Impact of Dysport Injections Early After Stroke on Upper Limb Spasticity Progression
The purpose of this study is to investigate if early administration (i.e. within 12 weeks after stroke) of Dysport® 500 U injections may delay the appearance or the progression of upper limb symptomatic spasticity.
- Trial name
- ONTIME Pilot (NCT02321436)
- Testing
- Botulinum toxin type A
- Where
- 4 sites in Malaysia, Philippines and 2 more
- Volunteers
- 42 people
- Sponsor
- Ipsen
Stroke
Evaluation of the Effect of Repetitive Peripheral Magnetic Stimulation on Upper Extremity Spasticity After Stroke
Spasticity is a frequent problem in post-stroke patients. It can negatively affect the functional recovery of patients and impair their quality of life.
- Trial name
- NCT05141695
- Testing
- therapeutic repetitive peripheral magnetic stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ankara University
Hemiplegia
HEMITOX : Effect of Botulinum Toxin Injections on Motor and Functional Ability of Upper Limb in Adults at Earlier Phases of Spastic Hemiplegia After Stroke
Botulinum toxin produced beneficial effects in spasticity in the hemiplegic upper limb. This study will test if botulinum toxin injections at earlier phases (<or = 3 months) in spasticity improve functional and motor tests…
- Trial name
- NCT00276185
- Testing
- Time delay treatment of botulinum toxin
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Clermont-Ferrand
Stroke, Hemiplegia
Functional Outcome of Hemiplegic Upper Extremity in Patients With Subacute Stroke After Kinesiotaping and Rehabilitation
1. To explore the role of sonoelastography with shear wave velocity to assess poststroke spasticity of affected arm and forearm muscles in patients with stroke. 2.
- Trial name
- NCT04027985
- Testing
- Kinesiotaping, Hand rehabilitation program
- Where
- Taiwan
- Volunteers
- 41 people
- Sponsor
- Chang Gung Memorial Hospital
Cerebrovascular Accident
A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GSK1358820 (Botulinum Toxin Type A) in Chinese Subjects With Post-stroke Upper Limb Spasticity
This trial is a multicenter, double-blind, randomized, placebo-controlled study to compare GSK1358820 (Botulinum Toxin Type A, also known as "OnabotulinumtoxinA" or "Botox") with placebo on the efficacy and safety of treatment in…
- Trial name
- NCT01153815
- Testing
- GSK1358820(Botulinum toxin type A)
- Where
- 13 sites in China
- Volunteers
- 170 people
- Sponsor
- GlaxoSmithKline
Stroke, Upper Extremity Dysfunction
REHABOTICS: Physiotherapy for Hand Spasticity After Stroke Using Robotics and AR Serious Games
Rehabotics is a comprehensive rehabilitation system designed to deliver individualized upper-limb therapy for patients with motor impairments, particularly after stroke.
- Conditions
- Stroke, Upper Extremity Dysfunction, Spasticity Post Stroke
- Trial name
- NCT07468149
- Testing
- Rehabotics Physiotherapy
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Pantelis Syringas
Post-stroke Upper Limb Spasticity
Comprehensive Protocol for Treatment of Upper Limb Spasticity in Post-stroke Hemiplegic Patients
The general objective of this study was to evaluate the efficacy of the comprehensive protocol in improving post-stroke upper limb spasticity.
- Trial name
- NCT05940805
- Testing
- Low-frequency transcranial electrical stimulation; Paraspinous block; Dry needling of spastic upper limb muscles; Muscular functional electrical stimulation (FES)
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo General Hospital
Post Stroke Arm Spasticity
Study to Document the Effectiveness of Dysport in Patients Suffering From Upper Limb Spasticity (ULS) After Stroke
The objective of this non-interventional study is to evaluate clinical effectiveness and cost effectiveness of Dysport within the reimbursement scheme called "drug programme" funded by Polish National Health Fund (NHF) for…
- Trial name
- PSAS REGISTRY (NCT02444494)
- Where
- 6 sites in Poland
- Volunteers
- 108 people
- Sponsor
- Ipsen
Stroke, Acute, Stroke, Ischemic
Prognosis and Diagnosis of Spasticity in Acute-post Stroke Patients
Spasticity, or greater muscle resistance, is a major disabling condition following stroke. Recovery of lost motor function in patients with stroke may be affected by spasticity, which most commonly develops in elbow and ankle…
- Conditions
- Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic, Spasticity as Sequela of Stroke
- Trial name
- NCT05179473
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- McGill University
Post Stroke Upper Limb Spasticity
To Evaluate HU-014 in the Treatment of Post Stroke Upper Limb
Investigational Product: LIZTOX inj 100unit(HU-014) Title : Multi Center, Phase III Clinical Trial to Evaluate the efficacy and Safety of LIZTOX Inj in the Treatment of Post Stroke Upper Limb Spasticity Sites and investigators …
- Trial name
- HU-014 (NCT05289921)
- Testing
- HU-014 Inj
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- Huons Co., Ltd.
Spasticity as Sequela of Stroke, Spastic Hemiplegia
Modulation of Upper Limb Spasticity Post-Stroke
Stroke is one of the commonest causes of severe disability in adults. Stroke often results in spasticity and motor impairments in the upper limb.
- Conditions
- Spasticity as Sequela of Stroke, Spastic Hemiplegia, Upper Extremity Dysfunction
- Trial name
- NCT05069480
- Testing
- Virtual reality-based training equipment., Traditional physical therapy program
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Umm Al-Qura University
Upper Limb Spasticity
Study of Intramuscular Injections of ABBV-950 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Spasticity
Spasticity is often observed as muscle tightness and stiffness in the upper and/or lower limbs. Upper limb spasticity can interfere with joint movement and its severity can range from mild to severe.
- Trial name
- NCT05956509
- Testing
- ABBV-950, BOTOX
- Where
- 9 sites in United States
- Volunteers
- 1 people
- Sponsor
- AbbVie