Clinical trials: Post Thoracotomy Pain
Post-thoracotomy Pain Syndrome
Effects of Dexmedetomidine Used in Continuous Thoracic Paravertebral Blocks
The purpose of this study is to explore the effectiveness of dexmedetomidine as an adjunctive analgesic, used in ultrasound-guided continuous thoracic paravertebral blocks for Post-thoracotomy Pain Syndrome(PTPS).
- Trial name
- NCT02619513
- Testing
- Dexmedetomidine, Ropivacaine, Mindray M7 series
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Weifeng Tu
Post Operative Pain
Comparison of Ultrasound-Guided Continuous Erector Spinae Plane Block Versus Thoracic Epidural Analgesia
There are limited studies comparing these two modalities ( thoracic epidural and erector spine block) for relieving the pain after thoracic surgeries .this study aim to investigate this purpose
- Trial name
- TEAVSESPB (NCT06571188)
- Testing
- THORACIC EPIDURAL BLOCK, ERECTOER SPINE BLOCK
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Menoufia University
Thoracotomy, Erector Spinae Plane Block
Efficacy of Ipsilateral High Thoracic Ultrasound-guided Erector Spinae Plane Block in Thoracic Cancer Surgeries
To evaluate the effectiveness of ultrasound guided Erector Spinae Plane Block (ESPB) in controlling post thoracotomy ipsilateral shoulder pain.
- Conditions
- Thoracotomy, Erector Spinae Plane Block, Thoracic Cancer, Shoulder Pain
- Trial name
- NCT05238688
- Testing
- Thoracic Epidural Analgesia (TEA) group, Thoracic Epidural Analgesia and Erector Spinae Plane Block (ESPB) group
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Cairo University
Postthoracotomy Pain
Comparison of Serratus Posterior Superior Intercostal Plane Block and Paravertebral Block for Post-Thoracotomy Pain Management
Patients undergoing thoracic surgery via thoracotomy are required to remain in the lateral decubitus position for prolonged periods due to surgical access requirements.
- Trial name
- NCT07768826
- Testing
- Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Paravertebral Block (PVB)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara City Hospital Bilkent
Thoracotomy Surgery, Anesthesia
Ultrasound-guided PVB
Thoracotomy, is a surgical procedure performed routinely in connection with pulmonary surgery. Pain induced by thoracotomy is considered as the most severe post-operative pain.
- Conditions
- Thoracotomy Surgery, Anesthesia, Ultrasound-guided PVB, Post-operative Pain
- Trial name
- BPV échoguidé (NCT01842698)
- Testing
- ultrasoundguided paravertebral catheter
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Jean Perrin
Acute Postthoracotomy Pain, Chronic Postthoracotomy Pain
The Effect of Paravertebral Block Using a Multi-orifice Catheter on Preventing Acute and Chronic Post-thoracotomy Pain
This study aims to evaluate the effect of the paravertebral block using a multi-lumen catheter on the incidence and severity of acute and chronic postthoracotomy pain compared to the thoracic epidural block.
- Conditions
- Acute Postthoracotomy Pain, Chronic Postthoracotomy Pain, Hypotension After Bolus Dose
- Trial name
- NCT01039870
- Testing
- paravertebral block, thoracic epidural analgesia
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Congenital Cystic Adenomatoid Malformation
Effects of Additional Fentanyl to Epidural Bupivacaine for Post-Thoracotomy Pain in Neonates
The study exams whether adding an opioid to the epidural infusion of a local anesthetic in neonates will significantly improve the quality of the postoperative analgesia.
- Trial name
- NCT00286143
- Testing
- Fentanyl
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Children's Hospital of Philadelphia
Thoracic Neuritis
Ultrasound-guided Serratus Block and the Emergence of Post-thoracotomy Pain Syndrome
The aim of this prospective, single blinded, comparative pilot study is to evaluate U/S guided serratus anterior plane catheter block (SAPB) versus patient-controlled analgesia (PCA) on the emergence of post - thoracotomy pain…
- Trial name
- NCT03533426
- Testing
- Serratus anterior plane catheter block, Patient controlled analgesia
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Chronic Pain, Thoracic
Chronic Pain After Cardiothoracic Surgery
This is a prospective cohort study to estimate prevalence of chronic pain after cardiothoracic surgery
- Conditions
- Chronic Pain, Thoracic, Chronic Pain Syndrome
- Trial name
- NCT05702125
- Volunteers
- 96 people
- Sponsor
- Universitas Indonesia
Pain, Postoperative
Flexibility of Cognition And Persistent Pain
This observational study aims to determine the association between preoperative cognitive flexibility and the risk of developing PPSP by preoperative administration of cognitive tests.
- Trial name
- FlexCAPP (NCT02579538)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Pain Following Thoracotomy Surgery
Study of Exparel Versus Epidural for Pain Control After Thoracotomy
Unilateral intercostal nerve blocks provide pain control as effectively as a continuous thoracic epidural, and will a lower incidence of side effects.
- Trial name
- NCT02178553
- Testing
- Epidural, Intercostal Bupivicaine (Exparel)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Mayo Clinic
Pain, Postoperative, Opioid Use
Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain
The goal of this pilot study is to describe and compare Ultrasound-Guided Erector Spinae Plane (ESP) Blocks using Exparel® (bupivacaine liposome injectable suspension) to Marcaine® (bupivacaine hydrochloride) for pain management…
- Conditions
- Pain, Postoperative, Opioid Use, Perioperative Complication, Heart Diseases
- Trial name
- NCT06077422
- Testing
- bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Rutgers, The State University of New Jersey
Chronic Pain
Efficacy of Compound Betamethasone Injection Combined With Ropivacaine in Ultrasound-guided Thoracic Paravertebral Nerve Block for Chronic Post-thoracotomy Pain
Chronic post-thoracotomy pain（CPTP）will not only have a negative impact on patients' physiology and psychology, but also affect postoperative recovery.A number of researches have demonstrated that Injury to the intercostal nerve…
- Trial name
- NCT05175001
- Testing
- Diprospan, Ropivacaine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Affiliated Hospital of Nantong University
Postoperative Pain, Postoperative Pain, Acute
Incidence of Chronic Pain After Thoracotomy
Thoracotomy is frequently performed in thoracic surgery. It is widely accepted that thoracotomy causes severe acute pain. Many factors such as postoperative analgesia treatment plan, operation time, number of chest tubes, and…
- Conditions
- Postoperative Pain, Postoperative Pain, Acute, Postoperative Pain, Chronic, Thoracotomy
- Trial name
- NCT05177575
- Testing
- Thoracotomy application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Persistent Pain, Postoperative Hyperalgesia
Prevention of Persistent Postsurgical Pain After Thoracotomy
Postthoracotomy acute pain is followed by persistent postsurgical pain in 20-30% of the patients, defined as pain that lasts more than 3-6 months after surgery.
- Trial name
- NCT01243801
- Testing
- Ketamine
- Where
- 2 sites in Spain
- Volunteers
- 104 people
- Sponsor
- Hospital Clinic of Barcelona
Post-thoracotomy Pain Syndrome
Erector Spinae Plane Block for Post-thoracotomy Pain Control
The thoracic epidural block (TEB) and thoracic paravertebral block (TPVB) are the most commonly used techniques for analgesia after thoracic surgery.Recently, erector spinae plane block (ESPB) was reported as a treatment for…
- Trial name
- NCT04531553
- Testing
- Thoracic epidural analgesia, ESPB with levobupivacaine and dexmedetomedine, ESPB with levobupivacaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Postoperative Pain
Evaluating Transcutaneous Electrical Nerve Stimulation for Postoperative Pain After Video-Assisted Thoracotomy Surgery
We propose to evaluate the use of Transcutaneous Electrical Nerve Stimulation (TENS) in patients having undergone Video-Assisted Thoracotomy Surgery (VATS) with the aim to determine if: Nurses will be able to apply TENS…
- Trial name
- NCT01046695
- Testing
- TENS Unit
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Mayo Clinic
Post-thoracotomy Pain
Duloxetine Role in Reducing Opioid Consumption After Thoracotomy
A total of 60 patients scheduled for thoracotomy with the aim of excision of pleural or lung cancer, will be randomized by the use of a computer-generated table of random numbers to receive duloxetine 60 mg orally 2 hours before…
- Trial name
- NCT03618225
- Testing
- Oral Duloxetine 60mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Thoracotomy Analgesia, Intrathecal Morphine
Intrathecal Morphine and Opioid Consumption After Thoracotomy
Thoracotomy is associated with some of the most severe postoperative pain of any surgical procedure. Inadequate analgesia restricts inspiratory effort and impairs the ability to cough, predisposing patients to atelectasis…
- Conditions
- Thoracotomy Analgesia, Intrathecal Morphine, Quality of Recovery (QoR-15), Opioid Consumption, Postoperative
- Trial name
- NCT07790250
- Testing
- İntercostal nerve block, Intrathecal Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Hypotension
Pilot Study: Paravertebral Analgesia vs Epidural Analgesia After Thoracotomy
Paravertebral analgesia is non-inferior to epidural analgesia for pain control and superior to epidural analgesia in terms of the main complication of hypotension.
- Trial name
- ParaEpi (NCT01700491)
- Testing
- Epidural Catheter 0.2% ropivacaine, Paravertebral Catheter 0.4% ropivacaine
- Where
- 2 sites in Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Manitoba