Clinical trials: Post Traumatic Stress Disorder
Posttraumatic Stress Disorder
A Retrospective And Multicenter Survey To Investigate The Dosage, Efficacy And Safety Of Sertraline In Posttraumatic Stress Disorder Patients
This is a multicenter retrospective study to investigate the dosage regimens of sertraline in the treatment of Posttraumatic Stress Disorder (PTSD) under current medical practice and the efficacy and safety of this drug in…
- Trial name
- NCT01607593
- Testing
- sertraline (Zoloft)
- Where
- 4 sites in Japan
- Volunteers
- 123 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Stress Disorders, Post-Traumatic, Combat Disorders
NightWare Randomized Trial 02
This study will provide preliminary estimates of safety and efficacy of the NightWare digital therapeutic system (iPhone + Apple watch + proprietary application) for the treatment of nightmare disorder associated with…
- Conditions
- Stress Disorders, Post-Traumatic, Combat Disorders, Ptsd, Nightmare
- Trial name
- TNT/NW (NCT04040387)
- Testing
- NightWare Therapeutic System
- Where
- 4 sites in United States
- Volunteers
- 270 people
- Sponsor
- NightWare
Stress Disorders, Post-Traumatic
A Ten-Week Study Evaluating The Effectiveness And Safety Of Zoloft In Children And Adolescents With A Diagnosis Of PTSD
To evaluate the safety and efficacy of sertraline compared to placebo in children and adolescents (6 to 17 years of age) who are outpatients with Posttraumatic Stress Disorder.
- Trial name
- NCT00150306
- Testing
- Zoloft (Sertraline)
- Where
- 23 sites in United States
- Volunteers
- 160 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
PTSD, Post Traumatic Stress Disorder
Feasibility of a Digital Therapeutic for Adults With Posttraumatic Stress Disorder (PTSD)
This study is exploring the efficacy of a digital therapeutic app in reducing symptoms of posttraumatic stress disorder (PTSD) in adults.
- Trial name
- NCT06868446
- Testing
- OTX-601 Digital Therapeutic - Version 1, OTX-601 Digital Therapeutic - Version 2, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oui Therapeutics, Inc.
Post-Traumatic Stress Disorder
Carvedilol Versus Placebo for Treatment in Post Traumatic Stress Disorder (PTSD)
The investigators hypothesize that carvedilol, at less then therapeutic doses for cardiac effect, will reduce symptoms of Post Traumatic Stress Disorder.
- Trial name
- NCT01221792
- Testing
- Carvedilol
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Columbia Northwest Pharmaceuticals
Post-Traumatic Stress Disorder, Stress Disorders, Post-Traumatic
Clinical Evaluation of BRL29060A (Paroxetine Hydrochloride Hydrate) in Posttraumatic Stress Disorder (PTSD)
This is a single-blind, placebo-controlled, parallel group study to evaluate the efficacy of BRL29060A (paroxetine hydrochloride hydrate, hereafter paroxetine) administered orally over the dose range of 20 mg to 50 mg once daily…
- Trial name
- NCT00557622
- Testing
- paroxetine
- Where
- 9 sites in Japan
- Volunteers
- 5 people
- Sponsor
- GlaxoSmithKline
PTSD
Study of Feasibility and Safety of MDMA-Assisted Group Therapy for the Treatment of PTSD in Veterans
The goal of this clinical trial is to learn if MDMA-assisted group therapy is safe and effective in in people with at least moderate PTSD.
- Trial name
- MPG1 (NCT05173831)
- Testing
- Midomafetamine, Therapy
- Sponsor
- Resilient Pharmaceuticals
PTSD
Safety and Efficacy Study of TNX-102 SL in Participants With PTSD
This is a 12-week, multicenter, randomized, double-blind, placebo-controlled, fixed-dose study that will investigate the efficacy and safety of 5.6 mg TNX-102 SL (2 x 2.8 mg tablets)-a sublingual formulation of cyclobenzaprine.
- Trial name
- NCT05372887
- Testing
- TNX-102 SL
- Where
- 3 sites in Kenya
- Sponsor
- Tonix Pharmaceuticals, Inc.
Post-Intensive Care Syndrome, Sedation
A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol
This pooled analysis will assess Cognitive, Mental Health, Functioning, and Quality of Life Assessments data from the Phase 3 registration studies INSPiRE-ICU 1 (NCT05312385) and INSPiRE-ICU 2 (NCT05327296) to explore potential…
- Trial name
- NCT06809218
- Testing
- Inhaled isoflurane administered by Sedaconda ACD-S, Intravenous infusion of propofol
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- Sedana Medical
Stress Disorders, Post-Traumatic
Sustaining Remission From PTSD Using Tuned Vibroacoustic Stimulation (TVS) Following MDMA-Assisted Psychotherapy
The purpose of this research is to examine a wearable device called Apollo that emits gentle vibrations found to benefit mood, energy, and focus.
- Trial name
- NCT05274230
- Testing
- Apollo Wearable
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Apollo Neuroscience, Inc.
Posttraumatic Stress Disorder (PTSD), Sleep Disturbances and Insomnia
A Study to Evaluate Effects on Sleep and Safety of RE03 in PTSD Patients With Sleep Disturbances
Post-traumatic stress disorder (PTSD) affects many people who have experienced traumatic events. A common issue with PTSD is severe sleep disturbances, such as nightmares.
- Trial name
- PTSD-PoC (NCT06685965)
- Testing
- RE03
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Reconnect Labs
Stress Disorder, Post Traumatic
EEG-based Personalized Transcranial Magnetic Stimulation (eTMS) to Treat Post-Traumatic Stress Disorder
This is a randomized, sham controlled study of the Electroencephalogram (EEG) based Transcranial Magnetic Stimulation (eTMS) treatment for Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT06892028
- Testing
- EEG-based personalized TMS
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- Wave Neuroscience
Posttraumatic Stress Disorder
MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD
The goal of this clinical trial is to learn if cognitive-behavioral conjoint therapy (CBCT) in combination with MDMA-assisted therapy is safe and effective in people with chronic PTSD and their partners.
- Trial name
- NCT02876172
- Testing
- MDMA, CBCT, Therapy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Resilient Pharmaceuticals
PTSD
7-Keto DHEA for the Treatment of PTSD
The purpose of this research study is to test the effectiveness of 7-Keto DHEA in reducing symptoms of Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT01861847
- Testing
- 7-Keto Dehydroepiandrosterone
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Humanetics Corporation
Post-traumatic Stress Disorder
Effectiveness of a Blended Care Parenting Intervention for Parents With PTSD (KopOpOuders-PTSD)
KopOpOuders-PTSD is a new preventive blended care intervention for parents with PTSD. The purpose of this study is to evaluate its effectiveness in improving parenting and preventing child mental health problems.
- Trial name
- NCT05237999
- Testing
- KopOpOuders-PTSD
- Where
- Netherlands
- Volunteers
- 142 people
- Sponsor
- Arkin
PTSD - Post Traumatic Stress Disorder
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool
The goal of the REVEAL PTSD study is to test how well the Senseye DT works as a diagnostic test for Post-traumatic Stress Disorder (PTSD) in adults 18 and older who are experiencing one or more symptoms that might be related to…
- Trial name
- NCT07280065
- Testing
- Senseye Diagnostic Tool (DT), Clinician Administered PTSD Scale for DSM-5, Revised Version
- Where
- 6 sites in United States, Australia
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- Senseye, Inc.
Post-Traumatic Stress Disorders, Posttraumatic Stress Disorders
Trial of Oral SNC-102 in Subjects With Combat-Related Posttraumatic Stress Disorder
This is a randomized, double-blind, placebo-controlled study of SNC-102 in adult subjects with cPTSD, added to pre-existing treatment that includes prazosin with or without other psychotropic drugs.
- Conditions
- Post-Traumatic Stress Disorders, Posttraumatic Stress Disorders, Stress Disorders, Post-Traumatic, Post-Traumatic Stress Disorders, Combat-related
- Trial name
- PTSD (NCT02384369)
- Testing
- SNC-102 sustained release tablet
- Sponsor
- Synchroneuron Inc.
PTSD
Safety and Efficacy Study of TNX-102 SL in Patients With Military-related PTSD
This is a 12-week, multicenter, randomized, double-blind, placebo-controlled, fixed-dose study that will investigate the efficacy and safety of 5.6 mg TNX-102 SL (2 x 2.8 mg tablets)-a sublingual formulation of cyclobenzaprine.
- Trial name
- HONOR (NCT03062540)
- Testing
- TNX-102 SL
- Where
- 44 sites in United States
- Volunteers
- 358 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Posttraumatic Stress Disorder
Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder
The goal of this clinical trial is to learn if MDMA-assisted therapy is safe and effective and reducing PTSD symptoms in veterans with chronic PTSD.
- Trial name
- NCT01211405
- Testing
- Low dose MDMA-assisted therapy, Medium dose MDMA-assisted therapy, Full dose MDMA-assisted therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Resilient Pharmaceuticals
Major Depressive Disorder (MDD, Anxiety Disorder, Generalized
Serotonin Variants & Gut Microbiota in Mental Health
This observational pilot study investigates whether a broad panel of genetic variants relevant to the serotonin pathway (including serotonergic system, methylation cycle, intestinal barrier integrity, and inflammatory response…
- Conditions
- Major Depressive Disorder (MDD, Anxiety Disorder, Generalized, Stress Disorders, Post-Traumatic, Panic Disorder
- Trial name
- NCT07634458
- Testing
- SNP Genotyping and Gut Metagenomics
- Volunteers
- 30 people
- Sponsor
- Neurobiologix