Clinical trials: Post Traumatic Stress Disorders
Post-traumatic Stress Disorder (PTSD), Acute Stress Disorder
EMDR Flash Group Protocol for Earthquake Survivors
This pilot randomized controlled trial evaluated the preliminary effects of the online EMDR Flash Group Protocol among adults affected by the 2023 Kahramanmaraş earthquakes in Türkiye.
- Conditions
- Post-traumatic Stress Disorder (PTSD), Acute Stress Disorder, Anxiety, Depression
- Trial name
- FlashGP-EQ (NCT07672613)
- Testing
- EMDR Flash Group Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Istanbul Galata University
Depression, Anxiety
Exploring the Role of Online Discussion Forums in Internet-Delivered Therapy for Canadian Public Safety Personnel
This study is a randomized trial designed to evaluate unguided (i.e., purely self-help), transdiagnostic internet-delivered cognitive behavioural therapy tailored specifically for public safety personnel both with and without a…
- Conditions
- Depression, Anxiety, Stress Disorders, Post-Traumatic
- Trial name
- NCT05145582
- Testing
- The Self-Guided PSP Wellbeing Course, Online Discussion Forum
- Where
- 2 sites in Canada
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Regina
Burn-Out Syndrome, Work-Related Stress Disorder
A Mindfulness Based Cognitive Therapy (MBCT) Resiliency Program for Critical Care Nurses
Developed over 10 years ago, Mindfulness Based Cognitive Therapy (MBCT) synergistically combines mindfulness training and cognitive behavioral therapy and can increase resiliency.
- Trial name
- NCT03132220
- Testing
- Mindfulness-Based Cognitive Therapy, Book Club Active Control Intervention
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Stress, Physiological, Stress, Psychological
Autonomic Modulation Training for Police Exposed to Post-Traumatic Stress Injuries
Police officers are exposed to hazardous, disturbing events that impose stress and long-term trauma. Upwards of 15-26% of public safety personnel (PSP) report one or more mental health symptoms.
- Trial name
- AMT (NCT05521360)
- Testing
- Autonomic Modulation Training
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Post Traumatic Stress Disorder, Depressive Symptoms
The Feasibility of Cognitive Process Therapy in Earthquake-affected Population With Mental Health Problems in Türkiye
The aim of the study is to test the pilot effectiveness of Cognitive Processing Therapy (CPT) in decreasing psychological distress and post-traumatic stress disorder (PTSD) symptoms and increasing well-being in earthquake…
- Conditions
- Post Traumatic Stress Disorder, Depressive Symptoms, Well-Being, Psychological, Anxiety Disorders and Symptoms
- Trial name
- NCT06136481
- Testing
- Cognitive Processing Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Koç University
Stress Disorders, Post-Traumatic
An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample
Given the high prevalence of post-traumatic stress disorder (PTSD) in veterans and active duty military, the focus of this research study is to test the reliability of two new PTSD assessments, the Clinician Administered PTSD…
- Trial name
- NCT04180930
- Testing
- CAPS-5, PSSI-5, CAPS-IV
- Where
- 3 sites in United States
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Stress Disorders, Post-Traumatic, Stress Related Disorder
Mindfulness-SOS for Refugees
Worldwide, refugees and asylum seekers suffer at high rates from trauma and stress-related mental health problems. The research group therefore developed, and initially piloted in a single-site open trial, a novel mindfulness…
- Trial name
- NCT05616286
- Testing
- Mindfulness-SOS for Refugees
- Where
- Israel
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Depressive; Episode, Major, Depression, Postpartum
Diagnostic Accuracy of the Stepped Screening Protocol and Its Screening Tools in the Perinatal Period.
It is known that 1 in 5 women experience psychological difficulties during their pregnancy or in the first year after giving birth.
- Conditions
- Depressive; Episode, Major, Depression, Postpartum, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- DAS (NCT05961306)
- Testing
- SCID 5
- Where
- 2 sites in Belgium
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
PTSD
Neural Circuits in Women With Abuse and Posttraumatic Stress Disorder
The purpose of this study was to assess the effects of the medication paroxetine on symptoms of posttraumatic stress disorder (PTSD) and the brain in women with a history of PTSD related to childhood abuse.
- Trial name
- NCT01681849
- Testing
- Paroxetine, Positron Emission Tomography (PET) Imaging
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Emory University
PTSD, Rape Sexual Assault
RRT for PTSD Symptoms in Survivors of Sexual Violence
Study to provide evidence of efficacy for Rapid Resolution Therapy in symptoms of PTSD, Anxiety, and Depression in survivors of sexual violence.
- Trial name
- NCT04073004
- Testing
- Rapid Resolution Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Depression, Stress Disorders, Post-traumatic
Cornerstone Program for Transition-Age Youth Study Protocol for a Randomized Controlled Trial
The purpose of this study is exploring a theoretically guided intervention, Cornerstone, which provides system 'boundary-spanning' services, including therapeutic services and mentorship, to transition-age youth with mental…
- Conditions
- Depression, Stress Disorders, Post-traumatic, Bipolar Disorder
- Trial name
- NCT02696109
- Testing
- Treatment As Usual, Cornerstone
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- New York University
Fear Anxiety, PTSD
Neuroimaging Memories of Fear and Safety in the Human Brain
The purpose of this research is to use functional magnetic resonance imaging (fMRI) to investigate how the brain forms associations between neutral and negative stimuli.
- Trial name
- NCT04975009
- Testing
- Fear conditioning
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Post Traumatic Stress Disorder
Efficacy of Single Dose IV Hydrocortisone in Post Traumatic Stress Disorder (PTSD) Prevention
This study is designed to test the hypothesis that a single Hydrocortisone intra venous injection within 6 hours post-trauma facilitates physiological recovery thereby preventing the development of Post Traumatic Stress Disorder…
- Trial name
- NCT00855270
- Testing
- Hydrocortisone
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Moral Injury
Moral Injury Study Among Healthcare Professionals in Psychiatric Facilities in the PACA Region
Healthcare professionals working in psychiatric settings face demanding working conditions characterized by high rates of burnout and specific constraints, such as the deprivation of patients' liberty.
- Trial name
- MI-PSY (NCT07631741)
- Testing
- Self-Questionnaires for Healthcare Workers
- Where
- France
- Volunteers
- 2,688 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Stress Disorders, Post Traumatic, Brain Injuries
Mind-Body Skills Groups for the Treatment of War Zone Stress in Military and Veteran Populations
The purpose of this study is to determine whether participation in mind-body skills groups by veterans who have experienced a stressful war-related situation and have symptoms of posttraumatic stress disorder (PTSD), will improve…
- Conditions
- Stress Disorders, Post Traumatic, Brain Injuries, Depressive Disorder, Anxiety Disorders
- Trial name
- NCT01093053
- Testing
- Mind-Body Skills Groups, Standard Treatment
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Center for Mind-Body Medicine
Intrusive Memories
The Effect of Oxytocin on the Acquisition and Consolidation of Trauma-Associated Memories
The purpose of the study is to examine whether oxytocin and oxytocin receptor gene polymorphism affect the development of intrusive memories, a cardinal symptom of PTSD.
- Trial name
- NCT03031405
- Testing
- Oxytocin nasal spray
- Where
- Germany
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Depression, Posttraumatic Stress Disorder
Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa
Pregnant women in South Africa (SA) are at high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP) use during pregnancy is both safe and effective in preventing HIV.
- Conditions
- Depression, Posttraumatic Stress Disorder, Pregnancy Related, Medication Adherence
- Trial name
- NCT05624931
- Testing
- Brief CBT-Based Intervention, Enhanced Treatment as Usual
- Where
- 2 sites in United States, South Africa
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Post-Traumatic Stress Disorder in Adolescence, Post Traumatic Stress Disorder
Adaptation of the PCIP for Spanish Speaking Adolescents and Families
This study will implement a brief Post-traumatic Stress Disorder (PTSD) intervention for children, the Primary Care Intervention for PTSD (PCIP) delivered through telehealth (computer or smart phone delivery), to 10 Spanish…
- Trial name
- NCT05899322
- Testing
- Primary Care Intervention for PTSD Spanish Speaking Adolescents, Waitlist Treatment as Usual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Anxiety Disorder, PTSD
Peer-led Group Intervention for Coping With Disaster
The present project partners with leading faith communities in Houston to provide expert-led educational workshops to a diverse sample of adults on normative and concerning response to disaster.
- Conditions
- Anxiety Disorder, PTSD, Depressive Symptoms, Anger
- Trial name
- NCT03907995
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Post-traumatic Stress Disorder, Post-Traumatic Stress Disorder, Chronic
PTSD Affect Labeling Study
The overall goal of this study is to use fMRI and psychophysiological measures to investigate a novel strategy involving "Affect Labeling" for improving emotion regulation in PTSD that could lead to a new treatment regimen for…
- Trial name
- NCT05924399
- Testing
- Affect Labeling Training
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles