Clinical trials: Post Traumatic Stress Disorders
Posttraumatic Stress Disorder
Examining an Emergency Room Intervention for the Prevention of Post Traumatic Stress Disorder (PTSD)
PTSD is a common and distressing possible outcome following exposure to a traumatic event. Recent studies show that memory processes may be central to the development of the disorder, and interrupting the consolidation of…
- Trial name
- NCT01162044
- Testing
- Computer game
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
PTSD
Can Exercise Improve Therapeutic Learning Among Women With Posttraumatic Stress Disorder
This study aims to test whether aerobic exercise improves the consolidation and subsequent recall of the learned safety memories among adult women with PTSD related to interpersonal violence exposure and whether this effect is…
- Trial name
- PTSD (NCT04417309)
- Testing
- Experimental, Active Control
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thomas Adams
Post Traumatic Stress Disorder
The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With Post Traumatic Stress Disorder (PTSD)
Oxytocin (OT) - a neurohormone and neuromodulator which is mainly synthesized in the hypothalamus - is a key mediator of complex social and affective behaviors, including emotional empathy.
- Trial name
- NCT01325168
- Testing
- syntocinon nasal spray
- Where
- 2 sites in Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Stress Disorders, Post-Traumatic
Evaluation of an Intensive Inpatient Psychotherapy Treatment for Severely and Early Traumatized Children (MOSES)
Evaluation of longitudinal treatment effects applying an intensive psychotherapeutic intervention for inpatients (age of participants: 6-13 years) with a multi-method-approach to address the complex nature of severe childhood…
- Trial name
- MOSES (NCT03894774)
- Testing
- Intensive in-patient psychotherapy treatment, Treatment as usual
- Where
- Germany
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Social Skills, Self-Criticism
Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking
The purpose of this randomized controlled trial is to evaluate an intervention, Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS).
- Conditions
- Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression
- Trial name
- NCT03488927
- Testing
- Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
- Where
- United States
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Posttraumatic Stress Disorder, Depression
The Pitt Center for Emergency Responder Wellness
Emergency responders protect the public despite occupational hazards that threaten their mental health. The Pitt Center for Emergency Responder Wellness will be a clinical innovation hub that: 1) delivers accessible interventions…
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety, Alcohol Use Disorder
- Trial name
- NCT05357586
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Substance Use Disorders, Posttraumatic Stress Disorder
Trauma Screening/Referral and Interpersonal Violence Prevention for Women with Substance Use Disorders
The purpose of this project is to implement a pilot study to investigate the feasibility and preliminary efficacy of a peer support specialist delivered violence prevention program for women in substance use treatment.
- Conditions
- Substance Use Disorders, Posttraumatic Stress Disorder, Opioid Use Disorder, Violence, Sexual
- Trial name
- NCT06608979
- Testing
- Screening/Referral and Prevention
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clemson University
Posttraumatic Stress Disorder
Using Attentional Bias Modification to Address Trauma Symptoms
Threat-related attentional biases have been identified as a possible precursor to the onset and maintenance of posttraumatic stress disorder (PTSD).
- Trial name
- NCT02615717
- Testing
- Attention Bias Modification
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
PTSD, Cardiovascular Disease
Lifestyle and Cardiometabolic Risk in Post-9/11 Veterans
Heart disease and diabetes are leading causes of death and disability in the US, especially among Veterans. Posttraumatic stress disorder (PTSD) is a disabling condition that also affects many Veterans.
- Conditions
- PTSD, Cardiovascular Disease, Metabolic Syndrome
- Trial name
- NCT04911153
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Quality of Life, Stigma, Social
App-based Psychosocial Intervention to Enhance Quality of Life in Arabic-speaking Refugees Residing in Switzerland
The ongoing warfare and economic instability in the Middle East and in North Africa causes many people to leave their home countries.
- Conditions
- Quality of Life, Stigma, Social, Depression, PTSD
- Trial name
- Sui (NCT05651737)
- Testing
- Sui App (SRK)
- Where
- Switzerland
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Bern
Posttraumatic Stress Disorder
Testing of a Mobile Web App to Decrease Posttraumatic Stress Symptoms in Women After Sexual Assault
Interventions are available to all adult women sexual assault survivors to reduce the risk of pregnancy and sexually transmitted infection, yet no interventions are provided to reduce posttraumatic stress.
- Trial name
- NCT04334356
- Testing
- Mobile Web App
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Borderline Personality Disorder
NEUROIMAGING OF ADOLESCENT BORDERLINE PERSONALITY DISORDER WITH AND WITHOUT POST-TRAUMATIC STRESS DISORDER
Borderline personality disorder (BPD) is a common mental disorder in adolescents with significant individual and societal repercussions, characterized over the long term by emotional hyperresponsiveness, relational instability…
- Trial name
- BorderStress (NCT04852744)
- Testing
- Brain MRI
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Preterm Delivery
Factors Associated With Post-Traumatic Stress Disorder in Patients With After Preterm Delivery
Each year in France, between 50,000 and 60,000 children are born prematurely (< 37 weeks of amenorrhea). Literature has shown that preterm deliveries can be associated with the development of PTSD (Post-Traumatic Stress Disorder)…
- Trial name
- PTSD-preterm (NCT03344471)
- Testing
- Passation of questionnaires
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Eco-anxiety, PTSD - Post Traumatic Stress Disorder
Assessing the Effects of Cool Roofs on Mental Health in Ahmedabad, India
Ambient air temperatures in India have broken record highs. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Eco-anxiety, PTSD - Post Traumatic Stress Disorder, Resilience, Anxiety
- Trial name
- REFLECT (NCT07251218)
- Testing
- Cool roof
- Where
- India
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Posttraumatic Stress Disorder, Anxiety Disorder
Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders
The aim of this project is to create fear conditioning paradigm within which the relative strengths of various novel pharmacological and behavioral interventions can be tested.
- Trial name
- NCT01631682
- Testing
- Propranolol, Reactivation, Mifepristone
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Post Traumatic Stress Disorder
Sleep and Emotion Processing in Adolescent Post-traumatic Stress Disorder
The goal of this clinical trial is to characterize the role of sleep, emotion processing, and daily affect in post-traumatic stress disorder (PTSD) and whether improving sleep quality using slow wave activity enhancement will…
- Trial name
- NCT06341413
- Testing
- SmartSleep device
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Psychological Trauma
A Couples' Intervention Protocol for PTSD
Posttraumatic stress disorder (PTSD) is a multifaceted disorder resulting from intense and/or life-threatening trauma. PTSD sequelae often have a ripple effect on close others, including spouses and children.
- Trial name
- NCT05045859
- Testing
- CBCT for PTSD
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Stress Disorders, Post-Traumatic
Gene Expression Correlates of Post-Traumatic Stress Disorder (PTSD) Symptom Change After EFT (Emotional Freedom Techniques)
The purpose of the study is to measure the change in psychological symptoms and gene expression in war veterans after a series of 10 EFT coaching sessions.
- Trial name
- NCT01250431
- Testing
- EFT (Emotional Freedom Techniques)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Soul Medicine Institute
Post-Traumatic Stress Disorder
Role of Substance P in Post-Traumatic Stress Disorder
This study will examine the role of substance P, a chemical messenger in the brain, in post-traumatic stress disorder (PTSD), a chronic anxiety disorder.
- Trial name
- NCT00102102
- Testing
- [18F]SPA-RQ
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Posttraumatic Stress Disorder, Stress
An Early Intervention to Increase Maternal Self-efficacy After Preterm Birth
This study aims to investigate the effects of an early intervention (joint observation and video feedback) on maternal parenting self-efficacy following a premature birth.
- Conditions
- Posttraumatic Stress Disorder, Stress, Anxiety, Depression
- Trial name
- JOIN (NCT02736136)
- Testing
- joint observation and video feedback
- Where
- Switzerland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois