Clinical trials: Post-Acute COVID19 Syndrome
Post-Acute COVID-19 Syndrome, Biofeedback, Psychology
Prevention of Long Covid Syndrome
Biofeedback equipment is classified by the Food and Drug Administration (FDA) as medical device class II and this type of equipment/treatment has shown evidence regarding stress management in post-Covid-19 syndrome.
- Conditions
- Post-Acute COVID-19 Syndrome, Biofeedback, Psychology, Quality of Life, Depressive Symptoms
- Trial name
- NCT05793736
- Testing
- Biofeedback training, Treatment as usual
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- University of Cagliari
Long COVID, Long COVID-19
RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)
The platform protocol is designed to be flexible so that it is suitable for a range of study settings and intervention types. Therefore, the platform protocol provides a general protocol structure that can be shared by multiple…
- Conditions
- Long COVID, Long COVID-19, Sleep Disturbance
- Trial name
- NCT06404112
- Testing
- Melatonin, Tailored lighting (TL) Active
- Where
- United States
- Volunteers
- 469 people
- Sponsor
- Duke University
COVID Long-Haul
Covid-19 Long Immunité IMagerie (CLIIM)
Covid-long pathology affects a large number of patients, and represents a major medical, economic and societal challenge. To date, we have no objective criterion for a definitive diagnosis, nor any predictive tool for monitoring…
- Trial name
- CLIIM (NCT06528171)
- Testing
- Brain MRI, Specific blood samples
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Long COVID, Postural Orthostatic Tachycardia Syndrome
The Long COVID-19 Wearable Device Study
To further characterize Long COVID-19 by collecting data from individuals who already own wearable devices or are provided with a wearable device along with basic and enhanced educational materials to determine if both can…
- Conditions
- Long COVID, Postural Orthostatic Tachycardia Syndrome, Dysautonomia, Myalgic Encephalomyelitis
- Trial name
- NCT05741112
- Testing
- Wearable device
- Where
- United States
- Volunteers
- 100,500 people
- Sponsor
- Scripps Translational Science Institute
Post-Acute COVID-19 Syndrome
A Study of Positive Emotions With Long COVID-19
This study is testing a new brief mindfulness practice for people suffering from long COVID-19 symptoms. People suffering from long COVID are particularly vulnerable to negative emotions, as they must also cope with the long-term…
- Trial name
- NCT05676008
- Testing
- Microdosing of mindfulness
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of California, Davis
Post-acute COVID-19 Syndrome
SENSING-AI Cohort for Long COVID Patients
The prospective study will focus on the collection of biometric and psychometric data from a limited population for 1 month with the aim of complementing the SENSING-AI retrospective cohort.
- Trial name
- SENSING-AI (NCT05204615)
- Testing
- Collection of clinical, psychometric and biometric data
- Where
- 2 sites in Spain
- Volunteers
- 10 people
- Sponsor
- Adhera Health, Inc.
Long Covid-19, PASC Post Acute Sequelae of COVID 19
A Pilot rTMS Trial for Neuropsychiatric Symptoms of Long-COVID
This is a pilot randomized trial of rTMS for symptoms of fatigue and brain fog, and other neuropsychiatric symptoms of Long-COVID (Post-COVID, post-acute sequelae of COVID-19 infection, PASC).
- Conditions
- Long Covid-19, PASC Post Acute Sequelae of COVID 19, Brain Fog, Fatigue
- Trial name
- NCT06586398
- Testing
- rTMS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Los Angeles
Long COVID Fatigue
Exploring the Therapeutic Effects of Creatine Supplementation for Long COVID-19
Individuals living with Long COVID often experiencing a degree of undue fatigue after physical or cognitive exertion secondary to the condition, timed post-exertional malaise 9PEM).
- Trial name
- NCT06992414
- Testing
- Creatine monohydrate
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Long COVID
Development of Voice Biomarkers of Frequent COVID-19 and Long Covid-related Symptoms Based on Data From Users of the Long COVID Companion App
The LIH DDP research team focuses its research topics on vocal biomarkers and Long COVID, among others. Voice is indeed a promising tool to monitor health, as it contains many information on our health and is easy to collect.
- Trial name
- EVO-LC (NCT07156994)
- Testing
- No Intervention: Observational Cohort
- Where
- Luxembourg
- Volunteers
- 300 people
- Sponsor
- Luxembourg Institute of Health
Long COVID, Post Acute Sequelae of COVID-19
Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine Trial - Effect of Hyperbaric Oxygen Therapy for the Treatment of Post COVID Condition
The RECLAIM study platform will be used to explore whether the use of Hyperbaric Oxygen therapy (HBOT) improves the symptoms of post covid cognitive dysfunction. Hyperbaric oxygen therapy is a well-established medical treatment.
- Conditions
- Long COVID, Post Acute Sequelae of COVID-19, Post-COVID-19 Condition
- Trial name
- RECLAIM-HBOT (NCT06452095)
- Testing
- Hyperbaric Oxygen therapy
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Long COVID
Long Covid (LC)-REVITALIZE - A Long Covid Repurposed Drug Study
The Long-Covid (LC)-Revitalize clinical study is testing repurposed drug treatments for Long Covid, involving adult participants from Brazil, Canada, Italy, South Africa, Uganda, the United States, and Zambia.
- Trial name
- NCT06928272
- Testing
- Pirfenidone, Upadacitinib
- Where
- 10 sites in United States, Brazil and 5 more
- Volunteers
- 348 people
- Sponsor
- Douglas D. Fraser
Covid19, Post-acute COVID-19 Syndrome
Effects of Respiratory Muscle Training in Individuals With Long-term Post-COVID-19 Symptoms
The main objective of the present study is to observe the short-term effects of respiratory muscle training combined with an exercise training program on quality of life and exercise tolerance in individuals with long-term…
- Trial name
- NCT05597774
- Testing
- Inspiratory + expiratory muscle training group, Exercise training program
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Universidad Complutense de Madrid
Long COVID, Long COVID Syndrome
Immunoadsorption in Autoimmune Long COVID
Some people continue to have serious symptoms long after COVID-19, such as extreme fatigue and feeling worse after activity. In some patients, this may happen because the immune system is attacking the body by mistake.
- Conditions
- Long COVID, Long COVID Syndrome, Long COVID-19 Syndrome, Post COVID Syndrome
- Trial name
- TURNLongCOVID (NCT07316127)
- Testing
- Immunoadsorption
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
COVID-19, Diabetes Mellitus
Incidence of Diabetes After a COVID-19 Infection
Prospective observational study of the POINTED consortium to evaluate whether new diagnoses of diabetes mellitus, occur significantly more frequently in the post-acute phase of a laboratory-confirmed SARS-CoV-2 infection than in…
- Trial name
- POINTED_Diab (NCT05524792)
- Testing
- no interventional study
- Where
- Germany
- Volunteers
- 157,134 people
- Sponsor
- InGef - Institute for Applied Health Research Berlin GmbH
Long COVID Fatigue, Brain Fog
Intensive Home-based Transcranial Direct Current Stimulation for Long COVID
The goal of this clinical trial is to learn if home-based transcranial direct current stimulation (tDCS) works to treat fatigue and other symptoms in adults with Long COVID.
- Conditions
- Long COVID Fatigue, Brain Fog, Chronic Pain, Depression Anxiety Disorder
- Trial name
- NCT07880171
- Testing
- Transcranial Direct Current Stimulation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital de Basurto
Long Covid
To Investigate Efficacy, Pharmacodynamics, and Safety of BC 007 in Participants With Long COVID
This study is an interventional, randomized, multinational, multicenter, double-blind, phase 2 study with a follow-up period of 90 days.
- Trial name
- BLOC (NCT05911009)
- Where
- 16 sites in Austria, Finland and 3 more
- Volunteers
- 119 people
- Sponsor
- Berlin Cures GmbH
Covid19, Functional Capacity
Functional Capacity in Survivors of COVID-19 Related ARDS
Acute respiratory distress syndrome survivors frequently develop impaired physical function, muscle weakness and quality of life.
- Conditions
- Covid19, Functional Capacity, Post-intensive Care Syndrome
- Trial name
- NCT04952844
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Koç University
Covid19, SARS (Disease)
Efficacy of Montelukast in Mild-moderate Respiratory Symptoms in Patients With Long-COVID-19:
Recently, a new clinical presentation called "long covid" has been reported, for patients with symptoms lasting for more than 4 weeks from the onset of the disease.
- Trial name
- E-SPERANZA (NCT04695704)
- Testing
- Montelukast
- Where
- 8 sites in Spain
- Volunteers
- 86 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Long Covid, Depression
Development of an Accessible Cognitive Behavioral Therapy Digital Therapeutic for Individuals With Long COVID
This study will evaluate Toivoa-004 as an experimental digital therapeutic for persons with Long COVID suffering from anxiety or depression.
- Conditions
- Long Covid, Depression, Anxiety
- Trial name
- NCT07714889
- Testing
- Rauha® Digital Therapeutic Platform (Toivoa-004)
- Sponsor
- Toivoa Inc
Post COVID-19 Condition, Post COVID-19 Condition (PCC)
Effects of Kneipp Hydrotherapy in Post-COVID-19 Patients
This randomized controlled study evaluates the effects of cold water hydrotherapy in patients with Post-COVID Syndrome. The primary aim is to assess changes in quality of life compared to an usual care setting without…
- Conditions
- Post COVID-19 Condition, Post COVID-19 Condition (PCC), Post COVID-19, Post COVID-19 Syndrome
- Trial name
- HydroCoVitalB (NCT07110714)
- Testing
- Cold water hydrotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Eggensberger OHG