Clinical trials: Post-COVID / Long-COVID
Post-COVID-19 Syndrome
Biomarker Analysis in Post-COVID Patients
Headache is one of the most common neurological manifestations of COVID-19. However, it is unclear whether chronic headache after the initial diagnosis, is associated with ongoing damage of the central nervous system.
- Trial name
- NCT05836428
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Post-acute Sequelae of SARS-COV-2 Infection
Effect of Apollo Wearable on Long COVID-19 Symptoms.
The purpose of this study is to examine how Apollo wearable use impacts symptoms and quality of life following long COVID.
- Trial name
- NCT06097442
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Board of Medicine
Long Covid, Depression
Development of an Accessible Cognitive Behavioral Therapy Digital Therapeutic for Individuals With Long COVID
This study will evaluate Toivoa-004 as an experimental digital therapeutic for persons with Long COVID suffering from anxiety or depression.
- Conditions
- Long Covid, Depression, Anxiety
- Trial name
- NCT07714889
- Testing
- Rauha® Digital Therapeutic Platform (Toivoa-004)
- Sponsor
- Toivoa Inc
Long COVID, Post COVID Condition
RECLAIM: Recovering From COVID-19 Lingering Symptoms Adaptive Integrative Medicine
The researchers propose to develop a Canada-wide, adaptive randomized clinical platform trial to assess the effectiveness of various interventions in patients with lingering symptoms of COVID-19 ("Long COVID").
- Conditions
- Long COVID, Post COVID Condition, Post Acute Sequelae of COVID-19
- Trial name
- RECLAIM (NCT05513560)
- Testing
- Ibudilast, Pentoxifylline
- Where
- 3 sites in Canada
- Volunteers
- 460 people
- Sponsor
- University Health Network, Toronto
Post-COVID19
Automatic Oxygen Titration in Patients After SARS-CoV-2 Infection
With the progression of the SARS-CoV-2 pandemic there's an increasing number of patients recovering from COVID19. Some of these patients still experience hypoxemia and therefore are still in need of a long-term oxygen therapy…
- Trial name
- NCT04849598
- Testing
- Oxygen therapy
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Schön Klinik Berchtesgadener Land
COVID-19
A Study to Understand How the Use of Paxlovid Affected Healthcare Use in People With Pre-existing Conditions.
This is a cohort study that will include Paxlovid (nirmatrelvir-ritonavir) treatment eligible for people with a positive SARS-CoV-2 diagnostic test and at least one COVID-19 symptom.
- Trial name
- NCT07090486
- Testing
- nirmatrelvir-ritonavir
- Where
- United States
- Volunteers
- 14,000 people
- Sponsor
- Pfizer
Conscripts, Military Induction Board
Prevalence of ENT Diseseas
The aim of the present study will be to evaluate in conscripts at the military induction board the prevalence of rhinosinusitis, the prevalence of HPV vaccinations, the prevalence of hearing impairments and the prevalence of…
- Conditions
- Conscripts, Military Induction Board, ENT Disease, Rhinosinusitis Chronic
- Trial name
- PrENT (NCT06105346)
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
COVID-19
Fascial Tissue Response to Manual Therapy: Implications in Long COVID-19
According to the World Health Organization (WHO), as of mid-September 2022, more than 21 million Brazilians have recovered from COVID-19.
- Trial name
- NCT06348186
- Testing
- Guidebook, Guidebook and Myofascial Reorganization® (RMF).
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of the State of Santa Catarina
COVID-19
Mechanisms Underlying Long-term Fatigue and Exercise Intolerance Following COVID-19
The MEXICO study is an observational study that aims to identify underlying mechanisms contributing to exercise intolerance in the presence of persistent COVID-19 symptoms (Long COVID).
- Trial name
- MEXICO (NCT04914754)
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- University College, London
Long COVID, Long COVID Syndrome
Evaluation of MicroRNAs and Vitamin B12 Expression in Subjects with Neurologic Symptoms of Depression, Anxiety and Fatigue in Long COVID-19
At the moment, the number of people with long COVID is unkown because there is still no effective diagnosis. This is why is very important to analyze the most common symptoms, which are: depression, anxiety and fatigue.
- Trial name
- NCT06864156
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Rehabilitacion
Parosmia
Stellate Ganglion Block With Lidocaine for the Treatment of COVID-19-Induced Parosmia
Chronic olfactory dysfunction, both hyposmia and parosmia, from the COVID-19 pandemic is a growing public health crisis, affecting up to 1.2 million people in the United States.
- Trial name
- Stella (NCT06055270)
- Testing
- Stellate Ganglion Block
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cognitive Dysfunction, Acquired Brain Injury
Fareon Open Label Device Clinical Trial
The purpose of this study is to assess the safety and feasibility of an at-home MMT treatment in patients with cognitive dysfunction related to acquired brain injury, Long COVID, traumatic brain injury, myalgic encephalomyelitis…
- Conditions
- Cognitive Dysfunction, Acquired Brain Injury, Traumatic Brain Injury
- Trial name
- NCT07600320
- Testing
- Fareon device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Long COVID, Long COVID Syndrome
Magnetic Resonance Analysis of Neural Inflammatory Factors and External Stimulation
The goal of this clinical trial is to test whether a type of rapid outpatient brain stimulation that uses magnetic fields, called accelerated intermittent theta burst stimulation (iTBS), can treat symptoms such as brain fog…
- Conditions
- Long COVID, Long COVID Syndrome, Long COVID-19 Syndrome, PASC
- Trial name
- MANIFEST (NCT06940609)
- Testing
- accelerated intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of New Mexico
Patients Post-COVID-19, Controls
Sequelae of COVID-19 With Focus on Exercise Capacity and Underlying Mechanisms
The project is designed as a cross-sectional study and aims to examine long-term consequences of coronavirus disease 2019 (COVID-19) for selected bio-behavioural parameters while taking the disease course severity into account.
- Trial name
- COR-PHYS (NCT05118711)
- Testing
- Cardiorespiratory fitness, Lung function, Muscular strength and balance tests
- Where
- Switzerland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Arno Schmidt-Trucksäss
Long COVID
DAOIB for the Treatment of Brain Fog
This is a 24-week open trial. We will enroll long-COVID patients with cognitive impairments. All patients will receive DAOIB for 24 weeks.
- Trial name
- NCT05764538
- Testing
- DAOIB
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Cognitive Impairment, Post-Acute Sequelae of SARS-CoV-2 Infection
Treatment of COVID-19 Post-acute Cognitive Impairment Sequelae With tDCS
After almost 2 years of pandemic, the consequences of the post-COVID syndrome, or PASC (Post Acute-Sequelae of Sars-CoV-2), have become a major challenge in the management of affected patients, generating costs for health…
- Conditions
- Cognitive Impairment, Post-Acute Sequelae of SARS-CoV-2 Infection, COVID-19
- Trial name
- PASC (NCT05389592)
- Testing
- Active tDCS and cognitive training
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Long COVID, Post COVID-19 Condition
Investigating the Effectiveness of Vimida
This randomized controlled trial (RCT) with 160 patients suffering from fatigue after COVID-19 infection aims to investigate the effectiveness of the unguided digital therapeutic vimida for reducing post-COVID-19 fatigue.
- Trial name
- InvidiCO (NCT06251518)
- Testing
- vimida
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Gaia AG
Vagus Nerve Diseases, Long COVID
Vagus Stimulation in Female Long COVID Patients.
The aim of the present pilot study is to investigate the acceptance, feasibility and implementation of the vagus nerv stimulation in Long COVID patients.
- Conditions
- Vagus Nerve Diseases, Long COVID, Long Covid19, Post-COVID-19 Syndrome
- Trial name
- Vagus (NCT05918965)
- Testing
- transcutaneous electrical vagal neurostimulation
- Where
- Austria
- Volunteers
- 45 people
- Sponsor
- Medical University of Vienna
Long Covid-19, PASC Post Acute Sequelae of COVID 19
A Pilot rTMS Trial for Neuropsychiatric Symptoms of Long-COVID
This is a pilot randomized trial of rTMS for symptoms of fatigue and brain fog, and other neuropsychiatric symptoms of Long-COVID (Post-COVID, post-acute sequelae of COVID-19 infection, PASC).
- Conditions
- Long Covid-19, PASC Post Acute Sequelae of COVID 19, Brain Fog, Fatigue
- Trial name
- NCT06586398
- Testing
- rTMS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Los Angeles
Post-Acute COVID-19 Syndrome, Long COVID
QEEG-NEUROFEEDBACK FOR COGNITIVE REHABILITATION IN LONG COVID-19 SURVIVORS WITH BRAIN FOG
The pandemic has highlighted social, economic, educational, and political issues that have affected the health and quality of life of millions of Brazilians.
- Conditions
- Post-Acute COVID-19 Syndrome, Long COVID, Brain Fog
- Trial name
- QEEG-NFT (NCT07005921)
- Testing
- qEEG-neurofeedback
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jade Carvalho Da Silva