Clinical trials: Post-COVID19 Condition
Long Covid
The Effect of Acupuncture Treatment on Cognitive Functions and Brain Networks for Long COVID
Background of study: Long COVID(LC) is a prevalent sequalae of SARS-CoV-2 infection and can affect multiple organ systems. Cognitive dysfunction is one of the most common symptoms in LC with 22% prevalence.
- Trial name
- NCT07355751
- Testing
- Acupuncture
- Where
- 2 sites in China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Tingting Luo
Anxiety, Depression
Difficulties in Emotion-regulation and Interpersonal Problems During and After the COVID-19 Pandemic
Central indicators of psychological functioning such as difficulties in emotion regulation and habitual problems in one's relating to others are likely to have been substantially impacted by the COVID-19 amelioration measures of…
- Conditions
- Anxiety, Depression, Interpersonal Problem, Emotion Regulation
- Trial name
- NCT04442282
- Volunteers
- 5,041 people
- Sponsor
- University of Oslo
COVID-19; and High Infection Risk of SARS-CoV-2
Tolerability,Safety,Pharmacokinetic Profile and Immunogenicity of a Recombinant Humanized Anti-SARS-CoV-2 Monoclonal Antibody (JS016) for Injection in Chinese Health Subjects
This is a randomized, double-blind, placebo-controlled, phase I clinical study to evaluate the tolerability, safety, pharmacokinetic profile and immunogenicity of JS016 (anti-SARS-CoV-2 monoclonal antibody) injection in Chinese…
- Trial name
- NCT04441918
- Testing
- JS016 (anti-SARS-CoV-2 monoclonal antibody)
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Junshi Bioscience Co., Ltd.
COVID 19
Impact of Cryopreservation Methods on Post-Thaw SARS-CoV-2 in Semen Samples
Cryopreservation of seminal fluid or spermatozoa from epididymary and testicular retrieval represents a crucial tool in managing conditions of permanent or temporary infertility, as well as in cases of secretory and excretory…
- Trial name
- SEM-COV-19 (NCT06703723)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Reproductive Disorder, Neurodegeneration
Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease
The objective of this protocol is to use a case-control paradigm to compare the response to an intravenous administration of kisspeptin in individuals with and without post-covid-19 syndrome.
- Conditions
- Reproductive Disorder, Neurodegeneration, SARS-CoV 2, Long COVID
- Trial name
- NCT07224490
- Testing
- Kisspeptin 112-121
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stephanie B. Seminara, MD
Sars-CoV-2 Infection, Long Covid19
Long Term Outcomes in COVID-19 Patients Recruited in the CORIST Project
Months after seemingly recovering from COVID-19, many patients continue to suffer from major long-term effects. Interestingly, the existence of direct link between the severity of the disease in its acute phase and the severity…
- Trial name
- CORIST-2 (NCT04907890)
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Insomnia, Metacognitive Beliefs
Insomnia After the COVID-19 Pandemic
The aim of this study is to investigate the levels of insomnia 3 months after (T2) the strict physical distancing government initiated physical distancing protocols related to the COVID-19 pandemic (T1).
- Conditions
- Insomnia, Metacognitive Beliefs, Anxiety, Depression
- Trial name
- NCT04443361
- Volunteers
- 5,000 people
- Sponsor
- University of Oslo
COVID-19, SARS-CoV-2 Infection
PET/CT Imaging in COVID-19 Patients
This is a PET/CT study using the 18F-αvβ6-binding-peptide.The goal of this study is to evaluate this peptide in patients after infection with SARS CoV2.
- Trial name
- NCT04376593
- Testing
- 18F-αvβ6-BP
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, Davis
Sarcopenia
Low Versus High-intensity Exercises in Sarcopenia
this study aims to compare the effect of high-intensity resistance exercises measured using the 10-repetition maximum versus low-intensity aerobic exercises on muscle performance, physical function and quality of life in chronic…
- Trial name
- NCT05593471
- Testing
- high intensity exercises, low intensity aerobic exercises
- Where
- Saudi Arabia
- Volunteers
- 82 people
- Sponsor
- University of Hail
Long COVID
Biomarkers of LONG COVID (LONG COVID_LCM)
This observational prospective study is aimed to investigate noncoding RNAs (ncRNAs) such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) as potential peripheral blood biomarkers of severity and poor prognosis in COVID-19…
- Trial name
- LONG COVID_LCM (NCT05672602)
- Testing
- Measurement of ncRNAs and cytokines
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Parosmia
Vitamin D Nasal Drops in Post COVID-19 Parosmia
The current study will be a pilot study for a randomized controlled trial conducted on patients recruited from the outpatient clinic of the Otorhinolaryngology Department, Menoufia Faculty of Medicine To evaluate the effect of…
- Trial name
- NCT05269017
- Testing
- Vitamin D3, Budesonide nasal spray
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Long COVID, Post-COVID Conditions
Transcranial Direct Current Stimulation for Long COVID Brain Fog and Fatigue
Long COVID can cause persistent symptoms such as fatigue, cognitive difficulties commonly described as brain fog, reduced exercise tolerance, and impaired quality of life.
- Conditions
- Long COVID, Post-COVID Conditions, Fatigue, Cognitive Dysfunction
- Trial name
- NEUROSTIM-LC (NCT07709234)
- Testing
- Transcranial Direct Current Stimulation
- Volunteers
- 20 people
- Sponsor
- University of Las Palmas de Gran Canaria
COVID-19
Pulmonary Rehabilitation Program With Pulsed Electromagnetic Field Therapy in Patients With Post-covid Sequelae.
Coronavirus 2019 disease can cause important sequelae in the patient, being one of the main affectations of the respiratory system due to bilateral pneumonia and frequently presenting loss of strength, dyspnea, polyneuropathies…
- Trial name
- NCT05379517
- Testing
- Pulsed ectromagnetid field therapy, Pulmonary rehabilitation program (PRP)
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- University of Malaga
Covid19, Environmental Exposure
Study on Kidney Disease and EnviromenTal Chemical
1. Purpose: To confirm the changes in lifestyle due to differences in perceptions of infectious disease risk after the COVID-19 pandemic, decrease in exposure levels of environmentally hazardous chemicals and changes in…
- Conditions
- Covid19, Environmental Exposure, Chronic Kidney Diseases
- Trial name
- NCT04679168
- Where
- South Korea
- Volunteers
- 310 people
- Sponsor
- Seoul National University Hospital
COVID-19
Immunogenicity and Safety of Booster Immunization of ZF2001 After Inoculation With Two Doses of CoronaVac
Study objectives: To evaluate the immunogenicity and immunity persistence and safety of recombinant novel coronavirus vaccine (CHO cells) after booster immunization in populations vaccinated with two doses of marketed novel…
- Trial name
- NCT05205096
- Testing
- Recombinant novel coronavirus vaccine (CHO cells)
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Long COVID-19, Post-COVID-19 Syndrome
Long Term Impact of COVID-19
COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, has a devastating effect on human lives, including over 6.6 million death as of November 2022.
- Conditions
- Long COVID-19, Post-COVID-19 Syndrome, COVID-19
- Trial name
- NCT05813574
- Testing
- Observational patient reported outcomes
- Where
- Netherlands
- Volunteers
- 835 people
- Sponsor
- Medisch Spectrum Twente
Smell Dysfunction, Taste Dysfunction
Post-Covid-19 Patients Follow-up Study
Taste, smell, trigeminal and salivary function is impacted in post-COVID-19 patients
- Conditions
- Smell Dysfunction, Taste Dysfunction, Trigeminal Dysfunction, Salivary Dysfunction
- Trial name
- COVID-19 (NCT07571382)
- Testing
- Smell training
- Where
- Norway
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University of Oslo
COVID-19
Efficacy and Safety of hzVSFv13 in Patients With COVID-19 Pneumonia
To explore the efficacy and confirm the safety of the concomitant administration of the standard of care and hzVSF-v13 in patients with COVID-19 infection
- Trial name
- NCT04679350
- Testing
- hzVSF-v13
- Where
- 3 sites in South Korea
- Volunteers
- 1 people
- Sponsor
- ImmuneMed, Inc.
COVID-19, Cytokine Storm
Fluoxetine to Reduce Intubation and Death After COVID19 Infection
This project will test the efficacy of fluoxetine to prevent serious consequences of COVID-19 infection, especially death. Becoming sick with COVID-19 virus or any other serious respiratory condition is not fun.
- Trial name
- NCT04377308
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toledo Health Science Campus
Long COVID, Chronic Fatigue Syndrome
Telerehabilitation for Post COVID-19 Condition
Telerehabilitation is a great alternative to offering care during a global pandemic. 85% of patients with COVID-19 report persistent symptoms up to 8 months after the infection.
- Trial name
- Telecovie (NCT05973136)
- Testing
- Telerehabilitation program based on cardiorespiratory principles
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Université de Sherbrooke