Clinical trials: Post-Catheter Ablation Atrial Arrhythmia Recurrence
Atrial Fibrillation
Efficacy of Dapagliflozin on Recurrence After Catheter Ablation for Atrial Fibrillation
This is a single-center, parallel-group, randomized, open-label trial evaluating the effect of 3-month treatment with dapagliflozin 10mg once daily on the recurrence of atrial fibrillation after catheter ablation for atrial…
- Trial name
- DARE-AF (NCT06433479)
- Testing
- Dapagliflozin 10 mg per day for 3 months after initial catheter ablation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation (AF), Atrial Fibrillation Patients Treated With the FARAPULSE™ PFA System
P-wave Duration and Local Potential as Predictors of AF Recurrence Following Pulmonary Vein Isolation
Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia worldwide and is associated with substantial morbidity, mortality, and healthcare utilization.
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation Patients Treated With the FARAPULSE™ PFA System, Atrial Fibrillation (Paroxysmal), Pulmonary Vein Isolation
- Trial name
- FOLLOW-AF (NCT07471308)
- Testing
- AF Recurrence RIsk Assessment post pulmonary vein isolation
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- CathVision ApS
Atrial Fibrillation
Comparison of Recurrence of Atrial Fibrillation Post Cryoballon Ablation During the 90-day Blanking Period-with and Without Anti-arrhythmic Drug Therapy
This study is being done to find out if patients taking Anti Arrhythmia Drugs (AADs) after cryoballoon ablation for atrial fibrillation, compared to patients who do not take Anti- Arrhythmic Drugs after an ablation affect Atrial…
- Trial name
- NCT02913014
- Testing
- No AAD post Ablation.
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Prisma Health-Midlands
Atrial Fibrillation (AF)
Evaluation of the Effectiveness and Safety of Remote Electrocardiographic Monitoring in Patients with Atrial Fibrillation Following Ablation Therapy
Background: Atrial fibrillation (AF) is the most common arrhythmia, significantly contributing to complications such as stroke, heart failure, dementia, and increased mortality.
- Trial name
- PREEMPT-AF (NCT06751459)
- Testing
- MEMO Patch 2 - 14-day Monitoring, MEMO Patch 2 - 1-day Monitoring, MEMO Link
- Where
- 7 sites in South Korea
- Volunteers
- 270 people
- Sponsor
- HUINNO Co., Ltd
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Reducing Recurrence of Symptomatic Atrial Fibrillation After Catheter Ablation by App-based Mental Training
Atrial fibrillation (AF) is one of the most common heart rhythm disorders and it is associated with a variety of symptoms leading to a considerable deterioration in quality of life.
- Conditions
- Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Meditation
- Trial name
- Mental-AF (NCT04067427)
- Testing
- Mental training
- Where
- Germany
- Volunteers
- 183 people
- Sponsor
- Helios Health Institute GmbH
Arrhythmias, Cardiac, Atrial Fibrillation
Clinical Cohort Study - TRUST
The "Long-term Outcome and Predictors for Recurrence after Medical and Interventional Treatment of Arrhythmias at the University Heart Center Hamburg" (TRUST) study is an investor-initiated, single-center, prospective clinical…
- Conditions
- Arrhythmias, Cardiac, Atrial Fibrillation, Atrial Flutter, Ventricular Tachycardia
- Trial name
- TRUST (NCT05521451)
- Where
- Germany
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Atrial Fibrillation
Effect of Enavogliflozin on Recurrence of Atrial Fibrillation After Catheter Ablation
Objective: The purpose of this study is to determine if there is a difference in the recurrence rate of atrial fibrillation (AF) between a group of patients with AF and heart failure undergoing catheter ablation who are…
- Trial name
- ENAVO-AF (NCT06528262)
- Testing
- Enavogliflozin
- Where
- South Korea
- Volunteers
- 390 people
- Sponsor
- Yonsei University
Pericardial Effusion
Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion
The effects colchicine administration for acute pericardial effusion after radiofrequency catheter ablation (RFCA) of atrial fibrillation on the recurrences of arrhythmia.
- Trial name
- NCT02260206
- Testing
- Colchicine
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yong Seog Oh
Atrial Fibrillation (AF)
Efficacy and Safety of Dapagliflozin in Preventing Atrial Fibrillation Recurrence After Catheter Ablation
Atrial fibrillation (AF) is a common arrhythmia, particularly prevalent in the elderly population. Catheter ablation is a common treatment for AF, but post-ablation recurrence of arrhythmias remains a significant clinical…
- Trial name
- NCT06740786
- Testing
- Dapagliflozin Treatment Group
- Volunteers
- 250 people
- Sponsor
- Xu Liu
Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction (HFpEF)
Tirzepatide on Atrial Fibrillation Recurrence After Catheter Ablation in Patients With Obesity and HFpEF
This multicenter, randomized, open-label, blinded-endpoint trial evaluates whether weekly subcutaneous tirzepatide for 12 months reduces atrial fibrillation (AF) recurrence after catheter ablation in adults with obesity and heart…
- Conditions
- Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction (HFpEF), Tirzepatide
- Trial name
- TEAR-AF-HFpEF (NCT07630454)
- Testing
- Tirzepatide, Structured Lifestyle Intervention
- Where
- China
- Volunteers
- 602 people
- Sponsor
- Yunlong Wang
Atrial Fibrillation (AF)
Acupuncture for Preventing Atrial Arrhythmia Recurrence After Ablation
This study aims to evaluate whether acupuncture can reduce the recurrence of atrial arrhythmias after catheter ablation in patients with persistent atrial fibrillation.
- Trial name
- NCT07487532
- Testing
- Electroacupuncture, Standard Medical Therapy
- Volunteers
- 120 people
- Sponsor
- Shanghai Zhongshan Hospital
Atrial Fibrillation
Effect of Hydroxychloroquine on Atrial Fibrillation Recurrence
Atrial fibrillation is the most common arrhythmia in clinic. It can lead to heart failure or stroke, and has a high disability rate and mortality rate.
- Trial name
- NCT03592823
- Testing
- Hydroxychloroquine Sulfate 200 Mg Tablet
- Where
- China
- Volunteers
- 240 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Atrial Fibrillation, Continuous Positive Airway Pressure
Clinical Study on the Effect of CPAP on AF Recurrence After Catheter Ablation in Patients with AF and OSA
Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice, significantly increasing the risks of death, stroke, heart failure, cognitive impairment, and dementia, thus severely impacting patients'…
- Conditions
- Atrial Fibrillation, Continuous Positive Airway Pressure, Obstructive Sleep Apnea, Recurrence
- Trial name
- NCT06542263
- Testing
- CPAP
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Atrial Fibrillation, Paroxysmal or Persistent
The SAFE Prospective Registry
Secretoneurin (SN) is a neuropeptide from the chromogranin family that influences intracellular calcium handling. SN suppresses calcium leakage from the sarcoplasmic reticulum through the ryanodine receptor.
- Trial name
- NCT05794464
- Testing
- Catheter ablation and/or electrical cardioversion
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Ostrava
Atrial Fibrillation
Usefulness of Markers to Predict Recurrence of Atrial Fibrillation After Radiofrequency Catheter Ablation
Catheter ablation using radiofrequency is a new therapeutic tool to treat atrial fibrillation with a higher success rate than medical therapy (80% versus less than 50% respectively).
- Trial name
- NCT00315068
- Where
- Switzerland
- Volunteers
- 180 people
- Sponsor
- University Hospital, Geneva
Atrial Fibrillation (AF)
Discontinuation of Anticoagulations After Successful Catheter Ablation of Atrial Fibrillation
The DESTINATION Study investigates whether anticoagulation therapy is necessary after successful catheter ablation (CA) for atrial fibrillation (AF).
- Trial name
- DESTINATION (NCT06615596)
- Testing
- discontinue anticoagulation therapy, Anticoagulant drugs, Catheter Ablation
- Where
- 12 sites in United States, China
- Volunteers
- 3,160 people
- Sponsor
- China National Center for Cardiovascular Diseases
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Inflammatory and Endothelial Function Response, and Arrhythmia Recurrence Following Catheter Ablation for Atrial Fibrillation
Current international guidelines recommend a three-month blanking period after pulmonary vein isolation (PVI) for atrial fibrillation (AF).
- Trial name
- NCT04269785
- Testing
- Cryoballoon ablation, Radiofrequency ablation
- Sponsor
- Karan Saraf
Atrium; Fibrillation, Atrium; Flutter
Refralon in Patients With Recurrence Paroxysmal and Persistent Forms of Atrial Fibrillation Who Underwent Catheter Ablation
It is planned to evaluate the efficacy and safety of the class III antiarrhythmic drug refralon as a drug for pharmacological cardioversion in patients with recurrent atrial fibrillation (AF) and atrial flutter (AFL) after…
- Trial name
- NCT05456204
- Testing
- Pharmacological cardioversion with Refralon
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Atrial Fibrillation
Pre Procedural Biomarkers Might Predict Recurrent Atrial Fibrillation After Catheter Ablation
Evaluation of the predictive value of serum levels of adipocytokines and primary phase reactant for recurrent atrial fibrillation (RAF) after catheter ablation in 26 patients had persistent and 91 patients had paroxysmal AF.
- Trial name
- NCT05114772
- Testing
- Measuring Serum bio-markers
- Where
- Egypt
- Volunteers
- 117 people
- Sponsor
- Tanta University
Atrial Fibrillation (AF)
The Modified "Pills-in-the-Pocket" Strategy
This is a multicentre, prospective, randomised controlled study of 328 patients with non-paroxysmal AF (within 5 years of first diagnosis of AF) with recurrent atrial arrhythmias after first catheter ablation, randomly divided in…
- Trial name
- ABD-AF (NCT06657404)
- Testing
- use Amiodarone, Bisoprolol and Digoxin
- Where
- China
- Volunteers
- 328 people
- Sponsor
- Yumei Xue