Clinical trials: Post-Concussion Syndrome
Brain Concussion, Post-Concussion Syndrome
Feasibility Testing of Cognitive Strategy Training in Post-Concussive Syndrome
This study will evaluate the practicality (i.e. acceptability to stakeholders; outcome battery feasibility; recruitment, retention, and adherence rates) and the preliminary effect of a cognitive strategy training intervention in…
- Trial name
- NCT04681742
- Testing
- CO-OP Group
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Missouri-Columbia
Brain Concussion, Mild Traumatic Brain Injury
Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches
This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI).
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Headache, Post-Concussion Symptoms
- Trial name
- NCT06112093
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Traumatic Brain Injury, Post-Concussion Syndrome
Fundamental and Applied Concussion Recovery Modality Research and Development: Applications for the Enhanced Recovery
This research is being done to understand the role of different recovery methods in healing time after athletic or sports related concussion.
- Conditions
- Traumatic Brain Injury, Post-Concussion Syndrome, Concussion, Brain
- Trial name
- NCT05062148
- Testing
- Float-REST, Photobiomodulation
- Where
- United States
- Sponsor
- West Virginia University
Post Concussion Syndrome, Head Injury
Evaluation of Two Treatments for Chronic Post Concussion Syndrome
This study is designed to investigate factors that are associated with prolonged recovery from mild head injury. The investigators are particularly interested in defining the impact of anxiety related variables, such as health…
- Trial name
- NCT00871884
- Testing
- Psychoeducation, Relaxation Training, Interoceptive Exposure
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Traumatic Brain Injury With Brief Loss of Consciousness, Post-Concussion Syndrome
mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms
Purpose of this study is to investigate the mechanisms of action of hyperbaric oxygen therapy for persistent post-concussive symptoms after mild tramatic brain injury
- Trial name
- BIMA (NCT01611194)
- Testing
- Hyperbaric oxygen (HBO2) at 1.5 atms
- Where
- 5 sites in United States
- Volunteers
- 71 people
- Sponsor
- U.S. Army Medical Research and Development Command
Post-Concussion Symptoms, Post-Traumatic Stress Disorder
Eye-Movement Desensitization and Post-Traumatic Syndroms
Millions people, all over the world, are admitted in the Emergency Department after a trauma or simply to receive medical cares. In France, it represents 10 million patients.
- Trial name
- SOFTER3 (NCT03400813)
- Testing
- R-TEP EMDR
- Where
- 2 sites in France
- Volunteers
- 314 people
- Sponsor
- University Hospital, Bordeaux
Brain Concussion, Post-Concussion Syndrome
Investigating the Physiological, Cognitive, and Psychological Effects of a Cognitive-Based Intervention
The primary purpose of this study is to investigate the effectiveness of a brief mindfulness-based intervention for targeting chronic physiological underarousal and post-concussive symptoms following a mild head injury (MHI), as…
- Trial name
- IPCPE-Mind (NCT02906449)
- Testing
- Meditation Technique
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Brock University
Concussion; Syndrome
Feasibility of a Purpose in Life Renewal Intervention for Adults With Persistent Symptoms After Concussion
A group of clinicians and researchers developed an 8-session group intervention that integrates education, support, self-reflection, and action-expectation to help people reaffirm or reconstruct self-grounded purpose after…
- Trial name
- PSC (NCT05780658)
- Testing
- Compass Course
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Mary Radomski
Post Concussion Symptoms
Effects of Anesthesia on Pediatric Surgical Patients With a History of Concussion - Phase I
The purpose of this research study is to determine the number of children who have symptoms of a concussion at the time they are scheduled for orthopedic surgery at Boston Children's Hospital.
- Trial name
- NCT02118220
- Testing
- Concussion Questionnaire
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Boston Children's Hospital
Concussion Post Syndrome, Headaches Posttraumatic
Pediatric Concussion Outcomes
This is a randomized, placebo-controlled, double-blinded trial in which subjects with a post concussive headache meeting inclusion criterion will be assigned to one of two treatment groups: placebo or nortriptyline.
- Conditions
- Concussion Post Syndrome, Headaches Posttraumatic, Mild Traumatic Brain Injury
- Trial name
- PeCon (NCT04226365)
- Testing
- Nortriptyline
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lancaster General Hospital
Traumatic Brain Injury, Post-concussion Syndrome
Measure of Cerebrovascular Dysfunction After TBI With fNIRS
The goal of this project is to determine if it is possible to assess Cerebrovascular Reactivity (CVR) to hypercapnia with functional Near Infrared Spectroscopy (fNIRS).
- Trial name
- NCT01789164
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Traumatic Brain Injury, Post-Concussion Symptoms
Brain Stimulation for Mild Traumatic Brain Injury
The purpose of this study is to determine the early effects of transcranial direct current stimulation (tDCS) in patients with mild traumatic brain injury and persistent post concussion syndrome(PPCS) with cognitive deficits in…
- Trial name
- tDCS/PPCS (NCT02292589)
- Testing
- Frontal Stimulation, Temporal Stimulation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo General Hospital
Congenital Heart Defect, Chronic Pain
Impacting Children's Physical and Mental Health Through Kinesiology Support in Clinical Care
Over the past four decades, it has become clear that childhood physical activity carries with it a myriad of beneficial effects.
- Conditions
- Congenital Heart Defect, Chronic Pain, Concussion Post Syndrome, Cerebral Palsy
- Trial name
- NCT04106154
- Testing
- Kinesiology Support
- Where
- Canada
- Volunteers
- 111 people
- Sponsor
- Children's Hospital of Eastern Ontario
Concussion Post Syndrome, Concussion
Effect of Vestibular Rehabilitation on Gait, Balance, and Coordination in Post Concussion Combat Athletes
This randomized controlled trial aims to evaluate the effectiveness of vestibular rehabilitation in improving gait and balance among post-concussion combat athletes aged 18-25 years.
- Trial name
- NCT07717528
- Testing
- Vestibular Rehabilitation Program, Conventional Post-Concussion Rehabilitation
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Concussion
Care for Post-Concussive Symptoms
The proposed study is a pilot randomized trial of a stepped collaborative care intervention designed to decrease post-concussive symptoms and improve post-injury functioning among sports-injured youth aged 11-17.
- Trial name
- CARE4PCS (NCT02268240)
- Testing
- Stepped Care
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Seattle Children's Hospital
Persistent Post-concussive Symptoms, Convergence Insufficiency
Persistent Post-Concussion Symptoms With Convergence Insufficiency
Our successful R01 discovered 1) the neural mechanistic difference between typically occurring convergence insufficiency (TYP-CI) and binocularly normal controls and 2) the underlying mechanism of office-based vergence and…
- Conditions
- Persistent Post-concussive Symptoms, Convergence Insufficiency, Mild Traumatic Brain Injury, Concussion, Mild
- Trial name
- PPCS-CI (NCT05262361)
- Testing
- Office-based Vergence and Accommodative Therapy
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- New Jersey Institute of Technology
Brain Concussion, Reflex, Pupillary
Utility of Pupillary Metrics in Diagnosis and Management of Concussion in Children
The purpose of this study is to gather information and compare the potential use of pupillometry to identify concussions and post concussive syndrome with standard age appropriate assessments.
- Conditions
- Brain Concussion, Reflex, Pupillary, Post-Concussion Syndrome, Brain Injuries, Traumatic
- Trial name
- NCT04540445
- Testing
- Pupillary Assessment
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Orange County
Post-concussion Syndrome, Post-concussive Symptoms
PLAY GAME: Post-concussion Syndrome in Youth - Assessing the GABAergic Effects of Melatonin
PURPOSE: The long-term goal of this line of research is to develop rational, biologically based evidence for the treatment of post-concussion syndrome (PCS) in children.
- Conditions
- Post-concussion Syndrome, Post-concussive Symptoms, Traumatic Brain Injury, Concussion
- Trial name
- PLAYGAME (NCT01874847)
- Testing
- Melatonin, Sugar pill
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Post-Traumatic Headache, Mild Traumatic Brain Injury
Efficacy and Tolerability of Erenumab in the Prophylactic Treatment of Persistent Post-Traumatic Headache
An exploratory open-label study of PPTH patients to study the efficacy and tolerability of erenumab in the prophylactic treatment of persistent headache attributed to mild traumatic injury to the head.
- Conditions
- Post-Traumatic Headache, Mild Traumatic Brain Injury, Post-Concussion Syndrome
- Trial name
- NCT03974360
- Testing
- AMG 334
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Danish Headache Center
Post-Concussion Syndrome, Post-Traumatic Headache
Digital Solutions for Concussion
The objective of this study is to develop new digital solutions for patients with prolonged postconcussion symptoms, and investigate its usability, feasibility, and safety.
- Trial name
- DiSCo (NCT05635656)
- Testing
- Digital symptom mapping and biofeedback treatment
- Where
- Norway
- Volunteers
- 23 people
- Sponsor
- St. Olavs Hospital