Clinical trials: Post-Concussive Syndrome
Post Concussive Symptoms
Chasing Biomarkers in Post-concussion Syndrome
The goal of this study was to investigate the biomarkers, neurofilament light chain, inflammatory markers, calcitonin-gene-related peptide, and metabolites from the kynurenine pathway in patients with severe post-concussive…
- Trial name
- NCT05812742
- Testing
- Early intervention programme, Enhanced usual care
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Persistent Post-Concussive Syndrome
Evaluation of a Physical Intervention for Persistent Post-Concussive Symptoms
A concussion occurs when a person receives an impact to the head. The most common persistent symptoms that generate from a concussion are headaches, depression, lack of balance and dizziness.
- Trial name
- NCT03357042
- Testing
- Aerobic exercise and balance retraining, Standard of care
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lakehead University
Post-Concussion Syndrome, Post-Traumatic Headache
Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology
The purpose of this study is to compare a 4-week, moderately intensive, lab and home-based aerobic exercise program versus exercise plus cognitive training.
- Conditions
- Post-Concussion Syndrome, Post-Traumatic Headache, Post-Concussive Syndrome, Chronic, Head Injury
- Trial name
- NCT03674398
- Testing
- Exercise+CT, Exercise only
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Traumatic Brain Injury, Post-concussive Symptoms
MEG and DTI of Neural Function and Connectivity in Traumatic Brain Injury
The overall hypothesis is that the long-term cognitive and behavioral sequelae of traumatic brain injury (TBI) are due to selective disruption of the long association white matter tracts of the cerebral hemispheres, with…
- Trial name
- Dana-REAC (NCT01298557)
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Post-concussion Syndrome, Post-concussive Symptoms
PLAY GAME: Post-concussion Syndrome in Youth - Assessing the GABAergic Effects of Melatonin
PURPOSE: The long-term goal of this line of research is to develop rational, biologically based evidence for the treatment of post-concussion syndrome (PCS) in children.
- Conditions
- Post-concussion Syndrome, Post-concussive Symptoms, Traumatic Brain Injury, Concussion
- Trial name
- PLAYGAME (NCT01874847)
- Testing
- Melatonin, Sugar pill
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Post Concussive Syndrome
An fMRI Study of Attention and Effort After Concussion
Approximately 1.1 million people a year suffer a mild traumatic brain injury (MTBI), or concussion, in the United States. Although most MTBI patients fully recover, as many as 28% have physical, cognitive, and/or emotional…
- Trial name
- NCT00653029
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Mild Traumatic Brain Injury, Post-Concussive Symptoms
Consistency of Automated Neuropsychological Assessment Metrics (ANAM) Performance in Those With Deployment Acquired Mild Traumatic Brain Injury (TBI)
The purpose of this project is to explore the degree to which performance consistency on neuropsychological measures varies in a sample of Operation Iraqi Freedom (OIF)/Operation Enduring Freedom (OEF) Veterans with a history of…
- Trial name
- ANAM (NCT01334528)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Traumatic Brain Injury, Post-concussive Syndrome
Sildenafil for Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury.
The purpose of this study is to determine whether sildenafil (Viagra®) is effective in improving cerebral blood flow and cerebrovascular reactivity inpatients who have persistent symptoms at least 6 months after a traumatic brain…
- Trial name
- NCT01762475
- Testing
- Sildenafil
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Post Concussive Syndrome, Chronic
Eye-Tracking Rapid Attention Computation
The purpose of this study is to validate and refine a diagnostic device that can detect attention and memory deficits that result from mild traumatic brain injury (mTBI).
- Trial name
- Eye-TRAC (NCT00743821)
- Where
- United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Brain Trauma Foundation