Clinical trials: Post-Intensive Care Syndrome
Post-Intensive Care Syndrome (PICS), Critical Illness Recovery
I-WEAR: Evaluating Wearables and Health Summaries in ICU Survivors
This pilot study investigates the use of wearable health technology and bi-weekly digital health summaries in patients recovering from intensive care.
- Conditions
- Post-Intensive Care Syndrome (PICS), Critical Illness Recovery, Coronary Artery Disease
- Trial name
- I-WEAR (NCT07035106)
- Testing
- Wearable Health Monitoring, Digital Health Summary and Lifestyle Counseling
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Ludwig Boltzmann Gesellschaft
Post-Intensive Care Syndrome, Quality of Life
Post-ICU Syndrome Over Time in Patients With Respiratory Failure
Intensive Care Units (ICU) stabilize and maintain vital functions in critically ill patients, optimizing their survival. However, patients with prolonged stays may develop Post-ICU syndrome , characterized by physical, cognitive…
- Trial name
- PICUS2 (NCT06857513)
- Testing
- Questionnaire and Physical Exam, EuroQol 5-Dimension 3-Level, EuroQol Visual Analogue Scale (EQ-VAS)
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Post-Intensive Care Syndrome
Application of Large Language Models Techniques to Post-ICU Syndrome Management in Critically Ill Patients: A Fully Longitudinal Mixed Study
The goal of this clinical trial is to evaluate whether Large Language Models (LLMs) combined with an optimized care program can effectively manage Post-Intensive Care Syndrome (PICS) in adult ICU survivors (aged ≥18 years)…
- Trial name
- NCT07141420
- Testing
- Routine Care, Health Promotion Model-Based Optimized Program, LLM-Enhanced Optimized Program
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Affiliated Hospital Of Guizhou Medical University
Delirium, Anxiety
Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study
Background: In the intensive care unit (ICU), delirium in patients and long-term mental health challenges in both patients and their family members are highly prevalent.
- Conditions
- Delirium, Anxiety, Post Intensive Care Unit Syndrome, Post Intensive Care Unit Syndrome Family
- Trial name
- FAM-ICU (NCT06974214)
- Testing
- FAM-ICU
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Post Intensive Care Unit Syndrome, Psychological Trauma
Positive Suggestions Via MP3 Messages
The purpose of this study is to assess the use of an audio recording containing positive suggestion as a means to provide needed psychological support to critically ill patients in a feasible and reliable manner.
- Conditions
- Post Intensive Care Unit Syndrome, Psychological Trauma, Anxiety, Depression
- Trial name
- NCT04437095
- Testing
- Psychological Support Based on Positive Suggestion delivered via pre-recorded MP3 message
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Mayo Clinic
Post Intensive Care Syndrome
Impact of Frailty and ICU-AW on Post-ICU Fatigue Self-reported
After a prolonged stay in Intensive Care Unit (ICU), fatigue is the most common symptom reported by patients in the Post Intensive Care Syndrome (PICS).
- Trial name
- FICUF (NCT05984069)
- Testing
- observational prospective data collection
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Post Intensive Care Syndrome (PICS), PTSD - Post Traumatic Stress Disorder
ICU-VR Prior to ICU Admission
Rationale: A substantial proportion of the Intensive Care Unit (ICU) survivors develop psychological impairments due to their ICU admission.
- Trial name
- NCT06642636
- Testing
- Intensive Care Unit-specific Virtual Reality
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Denzel Drop
Post-Intensive Care Syndrome, Sedation
A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol
This pooled analysis will assess Cognitive, Mental Health, Functioning, and Quality of Life Assessments data from the Phase 3 registration studies INSPiRE-ICU 1 (NCT05312385) and INSPiRE-ICU 2 (NCT05327296) to explore potential…
- Trial name
- NCT06809218
- Testing
- Inhaled isoflurane administered by Sedaconda ACD-S, Intravenous infusion of propofol
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- Sedana Medical
Delirium, Intensive Care Unit Delirium
Partnering With Family Members to Prevent, Detect and Manage Delirium in Critically Ill Patients.
Almost half of critically ill patients experience delirium. Delirium is associated with impaired cognition, mortality, and increased healthcare costs.
- Conditions
- Delirium, Intensive Care Unit Delirium, Post Intensive Care Unit Syndrome, Post Intensive Care Unit Syndrome Family
- Trial name
- NCT04099472
- Testing
- Delirium Education, Prevention, and Management, Standard Care
- Where
- 4 sites in Canada
- Volunteers
- 128 people
- Sponsor
- University of Calgary
Post Intensive Care Syndrome (PICS), Polypharmacy
The Critical Care Recovery Program: Use of a Structured Clinic Visit to Reduce Adverse Drug Events in ICU Survivors
Background and Objective: Intensive Care Units (ICUs) save lives, but many ICU survivors face ongoing health issues, including adverse drug events (ADEs) from medications started during their hospital stay.
- Conditions
- Post Intensive Care Syndrome (PICS), Polypharmacy, Adverse Drug Events, Critical Care, Intensive Care
- Trial name
- CCRP (NCT06723860)
- Volunteers
- 3,000 people
- Sponsor
- University of British Columbia
Post Intensive Care Unit Syndrome, Malnutrition
Micronutrient Levels and Nutritional Status in Critical Illness
Rationale: A significant proportion of patients admitted to the Intensive Care Unit (ICU) is unable to fully recover, even when the initial cause of their illness has been treated.
- Trial name
- NUTRI-ICU (NCT06119711)
- Testing
- No intervention
- Where
- Netherlands
- Volunteers
- 79 people
- Sponsor
- Frisius Medisch Centrum
Pediatric ALL, Critical Illness
Singapore's Health Outcomes After Critical Illness in Kids
What is the problem? Every year about 2.5 million children are affected by critical illness and require admission to the pediatric intensive care unit (PICU).
- Conditions
- Pediatric ALL, Critical Illness, Post Intensive Care Unit Syndrome
- Trial name
- SHACK (NCT04637113)
- Testing
- This is a non-interventional study
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Post Intensive Care Syndrome
Post-Resuscitation Interdisciplinary Consultation System: a Randomized, Multicenter, Interventional Study to Assess Quality of Life After a Stay in the COPRéa Intensive Care Unit
A patient's stay in the ICU is not without consequences and can cause various physical and/or psychological sequelae such as anxiety, depression, post-traumatic stress disorder (PTSD), physical weakness and memory problems.
- Trial name
- COPRéa (NCT05625867)
- Testing
- Psychological and quality of life questionnaires, Interdisciplinary consultation at 4/5 months
- Where
- France
- Volunteers
- 404 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Post-Intensive Care Syndrome (PICS)
ICU Biobank: Understanding Post-Intensive Care Syndrome (PICS)
The goal of this observational study is to explore the development and progression of Post-Intensive Care Syndrome (PICS) in adult ICU patients by establishing a biobank of biological samples and outcome data.
- Trial name
- NCT06671795
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Intensive Care Unit Delirium, Covid19
Delirium in Covid-19: Germany-wide Covid-19 Intensive Register
The global pandemic caused by the SARS-CoV-2 virus is confronting the German health system with a novel pathogen. This means that a timely evaluation of all available results is required.
- Conditions
- Intensive Care Unit Delirium, Covid19, Post Intensive Care Unit Syndrome
- Trial name
- NCT04775017
- Where
- Germany
- Volunteers
- 2,398 people
- Sponsor
- Charite University, Berlin, Germany
Post Intensive Care Syndrome
Risk Factors for the Occurrence of Post Intensive Care Syndrome (PICS)
Monocentric, observational, descriptive RIPH3 study with prospective data collection.
- Trial name
- PICS3 (NCT05534828)
- Testing
- A consultation
- Where
- France
- Volunteers
- 97 people
- Sponsor
- University Hospital, Toulouse
Acute Respiratory Distress Syndrome, Post Intensive Care Syndrome
The ICU LIBERATION Study
Acute respiratory distress syndrome (ARDS) is a condition associated with hypoxemia due to noncardiogenic causes and results in high mortality.
- Conditions
- Acute Respiratory Distress Syndrome, Post Intensive Care Syndrome, Treatment Compliance, Quality of Life
- Trial name
- LIBERATION (NCT05844579)
- Where
- Japan
- Volunteers
- 1,000 people
- Sponsor
- Japanese Society for Early Mobilization
Post Intensive Care Syndrome, Narrative Medicine
Effect of Pediatric Intensive Care Unit Diaries on PICS-p
When children become very sick and need to stay in a Pediatric Intensive Care Unit (PICU), it can have a big impact on their recovery and their family's well-being.
- Conditions
- Post Intensive Care Syndrome, Narrative Medicine, Post Traumatic Stress Disorder, Anxiety
- Trial name
- PICS-p (NCT06310109)
- Testing
- PICU diary
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Bambino Gesù Children's Hospital IRCCS
Ischemic Stroke, Post Intensive Care Unit Syndrome
Cytoflavin in the Rehabilitation of Post-intensive Care Syndrome in Stroke Survivors
Objective - to assess the effect of Cytoflavin® and its tolerability within the integrated program of rehabilitation of patients who underwent ischemic stroke
- Trial name
- NCT04194229
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
Acute Respiratory Failure, Post-Intensive Care Syndrome
Mobile Critical Care Recovery Program for Acute Respiratory Failure Survivors
The m-CCRP randomized controlled trial will evaluate the efficacy of a collaborative critical care recovery program from acute respiratory failure (ARF) survivors in accomplishing the Institute of Healthcare Improvement's triple…
- Trial name
- m-CCRP (NCT03053245)
- Testing
- Mobile Critical Care Program, Attention Control
- Where
- 3 sites in United States
- Volunteers
- 503 people
- Sponsor
- Indiana University