Clinical trials: Post-Mastectomy
Breast Cancer, Ductal Carcinoma
Nipple-Areola Complex (NAC) Irradiation After Nipple-Sparing Mastectomy and Reconstruction
The purpose of this research study is to see if a participant's nipple and areola can be safely preserved by adding radiation to these areas after a nipple-sparing mastectomy and immediate breast reconstruction.
- Trial name
- NCT01208974
- Testing
- Nipple-Sparing Mastectomy, Breast Reconstruction, Axillary Surgery
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Miami
Breast Cancer Female, Breast Cancer Prevent
First-in-human, Study of MATTISSE® Tissue Engineering Chamber in Adult Female Patients Undergoing Breast Reconstruction After Mastectomy for Cancer
This study is a first in human, two-stage single arm non-comparative study of safety and performance. The aim of the study is to asses the safety and the clinical performance of a new device : the MATTISSE tissu engineering…
- Conditions
- Breast Cancer Female, Breast Cancer Prevent, Breast Reconstruction
- Trial name
- TIDE (NCT05460780)
- Testing
- MATTISSE TEC
- Where
- 3 sites in France, Georgia
- Volunteers
- 50 people
- Sponsor
- Quanta Medical
Pain, Postoperative
Pecs Block vs Local Infiltration in Mastectomy
Studied the comparison between PECS II block and LIA on pain intensity, opioid requirements, RNL, and postoperative IL-6 levels in MRM patients.
- Trial name
- PBLIM (NCT06451705)
- Testing
- PECS II block, LIA
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Acute Pain, Anxiety
Effect of Aromatherapy Massage on Pain and Anxiety After Mastectomy
This study is an interventional type three-group randomized controlled non-drug clinical trial aimed at targeting the acute pain content and anxiety level of aromatherapy arm treatment with a sesame oil and sesame lavender oil…
- Conditions
- Acute Pain, Anxiety, Mastectomy, Massage Therapy
- Trial name
- NCT05658367
- Testing
- Aromatherapy massage with sesame- lavender oil mixed, Aromatherapy massage with sesame oil, Massage with parraffin oil
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Breast Cancer
Preoperative Evaluation of 3D Reconstruction Tool for Nipple-sparing Mastectomy
The goal of this clinical study is to explore whether preoperative application of 3D reconstruction tool can reduce the occurrence of ischemic complications in the flap and nipple areola complex after surgery.
- Trial name
- NCT06071234
- Testing
- 3D reconstruction technology
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Guangdong Provincial People's Hospital
Breast Cancer
Multidisciplinary Care Pathway With Electronic Patient Reported Outcomes (ePRO) Post-operative Follow-up of Breast Cancer Surgery Complications to Optimize Patient Quality of Life
This project is a follow-on study of the BEAUTIFY-2 study (NCT04957186). The "BEAUTIFY" (BrEast cAncer qUaliTy of lIfe aFter surgerY) program was built by a committee of experts on the basis of reflections carried out within 2…
- Trial name
- BEAUTIFY-3 (NCT05449340)
- Testing
- BEAUTIFY application
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Postmastectomy Lymphedema
Effect of CKC and WS Exercises on Postural Stability in Unilateral Post Mastectomy Lymphedema
Post-mastectomy lymphedema is one of the most common chronic complications that significantly impacts patients' quality of life following breast cancer surgery.
- Trial name
- NCT06977620
- Testing
- Closed kinetic chain exercises, Weight shifting exercises, Complete Decongestive Therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Peripheral Nerve Block Procedure
Prospective Post-market Evaluation of an Echogenic Catheter
Patients scheduled for mastectomy and suitable for paravertebral block will be randomized to one of 2 groups. Group 1 will have the nerve block performed using a standard non-echogenic needle and catheter under ultrasound…
- Trial name
- EchoCath (NCT02136446)
- Testing
- EchoGlo Nerve Block Catheter, Pajunk® Nerve Block Catheter
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Smiths Medical, ASD, Inc.
Analgesia
Regional Block for Post-mastectomy Analgesia
A large number of patients undergoing major surgical procedures for the management of breast cancer complain of acute and chronic postoperative pain.
- Trial name
- NCT07683416
- Testing
- Serratus-intercostal plane block, Erector spinae plane block, Dexmedetomidine Injection
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Zagazig University
Post-mastectomy Pain Syndrome
Comparison of Kinesiotaping and Graded Exposure Therapy on Kinesiophobia in Post-Mastectomy Patients
The aim of this research is to compare the effect of Comparison of Kinesiotaping and Graded exposure therapy on Kinesiophobia in Post-Mastectomy patients. The sample size was 30.
- Trial name
- NCT06658314
- Testing
- Experimental interventional group 1(Kinesiotaping), Experimental interventional group II (Graded exposure therapy)
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Breast Cancer
Dexamethasone Versus Dexmedetomidine as Adjuncts to Serratus Anterior Plane Block
Modified radical mastectomy is the most commonly performed surgical approach for breast cancer. The procedure enables surgeons to remove the main tumor mass, adjacent glandular tissue and regional lymph nodes.
- Trial name
- NCT06300099
- Testing
- Dexamethasone, Dexmedetomidine
- Volunteers
- 126 people
- Sponsor
- Al-Azhar University
Web Based Intervention, Mastectomy
Web-Assisted Interactive Nurse Program in Mastectomy Patients: A Mixed Method Study
This study is planned to examine the levels of bodily value, care dependence and psychosocial cohesion-self-notification of patients in the Web Assisted Interactive Nursing Program (WDIHP) designed according to the Self…
- Conditions
- Web Based Intervention, Mastectomy, Illness Perception, Nursing Caries
- Trial name
- Mastectomy (NCT05222763)
- Testing
- Web-assisted patient education intervention designed according to the self-regulation model, The website where the mastectomy patients handbook
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Breastcancer, Mastectomy
Study Evaluating the Efficacy of Loco-regional Anaesthesia PECS on Chronic Pain of a Mastectomy
A non-randomized, mono-centric, prospective interventional study that will assess the efficacy of the loco-regional anesthesia PECS on the rate of chronic pain, 6 month after a patient will have either received a mastectomy or a…
- Trial name
- PECS (NCT03023007)
- Testing
- Loco-regional anaesthesia
- Where
- France
- Volunteers
- 194 people
- Sponsor
- Centre Oscar Lambret
Breast Carcinoma, Breast Reconstruction
Prepectoral and Subpectoral Implant-based Breast Reconstruction
Breast cancer is one of the main malignant tumors threatening women's lives. In recent years, the increasing demand for reconstruction of breast cancer patients in China has made the proportion of breast reconstruction increase…
- Trial name
- NCT04688697
- Testing
- prepectoral implant-based reconstruction, subpectoral implant-based reconstruction
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Fudan University
Breast Cancer
Mirtazapine for Acute and Chronic Post Mastectomy Pain
Our aim in this study will be to investigate the effect of mirtazapine on acute post-mastectomy pain manifested by total morphine consumption in first 24 hours and VAS score at rest and movement (primary outcomes).
- Trial name
- NCT06499090
- Testing
- Mirtazapine 30 MG
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Locoregional Analgesia in Breast Surgery
Double-blind Study to Assess effectIveness of Pectoral Nerves Block After Breast Surgery on Piritramide Consumption
The aims of this study is to compare the effectiveness of pecs block associated to a general anesthesia in terms of Piritramide consumption compared with a general anaesthesia alone and the chronic pain incidence in patients that…
- Trial name
- DESIGN (NCT02655965)
- Testing
- Ropivacaine, Clonidine, Sodium Chloride
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Jules Bordet Institute
Lymphedema
Underwater Galvanic Stimulation by 4-Cell Bath on Lymphedema.
Sixty female patients with lymphedema post mastectomy, aged 30-55 years, will be selected from Minia Oncology Institute. The participants will be randomly distributed into two equal groups: 1.
- Trial name
- NCT06753175
- Testing
- underwater galvanic stimulation by 4-cell bath, Complete Decongestive Therapy (CDT):
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Breast Reconstruction After Mastectomy
National, Multicenter PMS Study "Patient Reported Outcome" in Breast Reconstruction Following Mastectomy With TiLOOP Bra
This multicentre, non-randomised, observational clinical device investigation will be performed to obtain postmarketing information on the TiLOOP® Bra and in particular on the improvement of the patients' quality of life as well…
- Trial name
- PRO-BRA (NCT01885572)
- Testing
- TiLOOP Bra
- Where
- 8 sites in Germany
- Volunteers
- 267 people
- Sponsor
- Pfm Medical Mepro Gmbh
Mastectomy, Nerve Block
Effect of Pectoralis Block on Analgesia After Simple Mastectomy
The pectoralis block, including pecs I and II block, is a novel technique first described in 2011 as an alternative to paravertebral blockade for analgesia following breast surgery.
- Conditions
- Mastectomy, Nerve Block, Analgesia, Postoperative
- Trial name
- NCT03143530
- Testing
- Pectoralis block, Normal saline injection, Ropivacaine Injection
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Breast Cancer
Can Methylprednisoloneacetate Prevent Seroma After Mastectomy for Primary Breast Cancer
A randomised double-blinded study, in which the patients either get methylprednisoloneacetate or saline solution in the mastectomy cavity to evaluate the efficacy of methylprednisoloneacetate in preventing seroma in patients…
- Trial name
- NCT01380912
- Testing
- methylprednisoloneacetate
- Where
- 2 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital at Herlev