Clinical trials: Post-Mastectomy
Breast Cancer, Mastectomy; Lymphedema
Myofascial Massage for Pain and Immobility Following Breast Cancer Surgery
About 25-50% of women who undergo breast cancer surgery develop persistent chest wall pain and shoulder mobility limitations following surgery.
- Conditions
- Breast Cancer, Mastectomy; Lymphedema, Pain, Shoulder, Mobility Limitation
- Trial name
- NCT04233385
- Testing
- Myofascial Massage, Light Touch
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- MetroHealth Medical Center
Lymphedema Arm
Immersive Virtual Reality Based Exersice in Post-mastectomy Lymphedema Patients
To determine the effect of immersive virtual reality on shoulder proprioception and ROM of post-mastectomy lymphedema patients.
- Trial name
- NCT06553183
- Testing
- immersive virtual reality, traditional physicaltherapy
- Volunteers
- 60 people
- Sponsor
- Cairo University
Breast Neoplasms
Intra-operative Radiotherapy For Breast Cancer Women After NSM
The role of NSM is still controversial, mainly because of concern about the oncologic safety of the nipple-areola complex (NAC).INTRABEAM (Carl Zeiss, Oberkochen, Germany) is the most widely used mobile intraoperative…
- Trial name
- NCT02389686
- Testing
- INTRABEAM (Carl Zeiss, Oberkochen, Germany)
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Liao Ning
Breast Cancer, Pain
Pain After Tumescent Mastectomy or Standard Mastectomy in Women With Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: New surgery techniques may lessen pain after breast surgery. It is not yet known whether tumescent mastectomy or standard mastectomy results in less pain in women with breast cancer.
- Conditions
- Breast Cancer, Pain, Perioperative/Postoperative Complications
- Trial name
- NCT00859157
- Testing
- therapeutic conventional surgery
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of California, Davis
Breast Cancer Surgery, Transcutaneous Electric Nerve Stimulation
Effects of Transcutaneous Electrical Nerve Stimulation on Breast Surgery
The aim of this randomized controlled trial was to evaluate the effects of transcutaneous electrical nerve stimulation (TENS) on postoperative pain, lymphedema development, shoulder range of motion, and quality of life in women…
- Trial name
- NCT06973265
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Seda Akutay
Breast Cancer
Delayed-Delayed Breast Reconstruction
The goal of this clinical research study is to learn if delayed-delayed breast reconstruction in women who require post-mastectomy radiation therapy will improve cosmetic outcomes and result in fewer complications compared to the…
- Trial name
- NCT01256528
- Testing
- Delayed Breast Reconstruction
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Postoperative Pain After Breast Reconstruction With Abdominal Flap
Postoperative Pain Control With Fentanyl Patch in Patients Undergoing Mastectomy and TRAM or DIEP Flap Reconstruction
The aim of this randomized, double-blind controlled trial is to determine the efficacy of transdermal fentanyl for the management of early postoperative pain in women undergoing mastectomy followed by immediate TRAM or DIEP flap…
- Trial name
- Fentanyl Patch (NCT01258296)
- Testing
- Fentanyl, Inactive patch
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Breast Cancer, Postoperative Pain
Ultrasound-Guided SPSIP Versus ESPB for Postoperative Pain After Modified Radical Mastectomy
Breast cancer is the most common cancer affecting women worldwide. Modified radical mastectomy is one of the main surgical treatments for breast cancer.
- Conditions
- Breast Cancer, Postoperative Pain, Acute Post-surgical Pain
- Trial name
- SPSIP-ESPB (NCT07446868)
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Chronic Pain
Intraoperative Ketamine on Chronic Pain After Mastectomy
Preventive analgesia is when an administered analgesic drug provides reduction in pain beyond its duration of action. This can be used to reduce acute postoperative pain and prevent occurrence of chronic post-surgical pain.
- Trial name
- NCT02729805
- Testing
- Saline, Ketamine 0.5mg/kg, Ketamine 0.75mg/kg
- Where
- Hong Kong
- Volunteers
- 135 people
- Sponsor
- The University of Hong Kong
Drug Effect
Comparison of Duloxetine Versus Pregabalin
Chronic post mastectomy pain syndrome (PMPS) is a chronic post-surgical neuropathic pain following breast cancer surgeries and lasting more than three months after surgeries.
- Trial name
- NCT04727502
- Testing
- Duloxetine, Pregablin
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- National Cancer Institute, Egypt
Post-mastectomy Pain Syndrome
Adding Magnesium Sulphate to Combined Pectointercostal Plane and Erector Spinae Plane Blocks for Acute and Chronic Post-Mastectomy Pain
Given the burden of chronic postmastectomy pain and the need for effective, opioid-sparing analgesia, the propose of the randomized controlled trial is to evaluate the safety and efficacy of adding magnesium sulphate to the…
- Trial name
- NCT07438366
- Testing
- Pectointercostal Plane Block (PIPB), Erector Spinae Plane Block (ESPB), Magnesium sulfate
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Breast Cancer
Dead Space Closure With Quilting Suture Versus Conventional Closure With Drainage
The objective of this study is to compare quilting suture of the "dead space" without drainage of the pectoral area to conventional closure with drainage to prevent post-operative seroma requiring intervention (aspiration or…
- Trial name
- QUISERMAS (NCT02263651)
- Testing
- Quilting suture without drainage, Conventional closure with drainage
- Where
- 6 sites in France
- Volunteers
- 320 people
- Sponsor
- University Hospital, Tours
Postoperative Pain
Effect of Postoperative Single Dose of Ketamine on Pain After Mastectomy
This is a randomized, single blinded, placebo-controlled trial to study the effectiveness of a subanesthetic dose (0.6mg/kg) of ketamine versus placebo (saline) on postoperative pain on adult women undergoing mastectomy.
- Trial name
- NCT04831736
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- NYU Langone Health
Breast Cancer, Radiation Toxicity
Hypofractionated Versus Conventional Fractionation Radiotherapy
This study was designed to evaluate the acute toxicity and quality of life of hypofractionated radiation versus conventional when regional node irradiation is indicated after breast-conserving surgery or mastectomy.
- Trial name
- NCT04015531
- Testing
- Conventional radiotherapy, Hypofractionated radiotherapy
- Volunteers
- 80 people
- Sponsor
- Hospital da Baleia
Pain After Mastectomy
ROPI Study : Ropivacaine Interest in Postsurgical Pain After Mastectomy
After surgery for breast cancer, the prevalence of chronic pain is estimated between 20 and 68%. They begin after surgery and may persist until more than 6 months.
- Trial name
- ROPI (NCT01855529)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Jean Perrin
Breast Cancer
Immediate Implant Breast Reconstruction
The purpose of this study is to study the impact of the immediate implant breast reconstruction for patients with mastectomy and postoperative chest wall radiotherapy
- Trial name
- ISIS (NCT02055937)
- Testing
- immediate implant breast reconstruction
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Breast Cancer
Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control
The purpose of this study is to compare using FDA-approved bupivacaine (a numbing medicine), along with the usual medications for post-operative pain control to using the usual medications for postoperative pain control alone.
- Trial name
- NCT03351348
- Testing
- Bupivacaine, patient-reported pain scores, saline
- Where
- 7 sites in United States
- Volunteers
- 165 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
Implant-based Breast Reconstruction and Mastectomy With Fat Grafting After Breast Conserving Surgery and Radiotherapy
Higher rates of complications and poorer cosmetic outcomes have been reported after salvage mastectomy and implant-based versus autologous reconstruction in patients previously exposed to radiation therapy (i) on the breast as…
- Trial name
- NCT06119633
- Testing
- Immediate tissue expander and lipofilling after mastectomy
- Where
- 2 sites in Italy
- Volunteers
- 163 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Pain, Acute, Erector Spinae Plane Block
Effect of Ultrasound Guided Thoracic Interfascial Plane Block Versus Erector Spinae Plane Block After Mastectomy
This study will be conducted to compare the efficacy of ultrasound guided thoracic interfascial plane block versus ultrasound guided erector spinae plane block on acute and chronic pain after modified radical mastectomy surgery.
- Conditions
- Pain, Acute, Erector Spinae Plane Block, Mastectomy, Modified Radical, Thoracic Interfascial Plane Block
- Trial name
- NCT05176938
- Testing
- Ultrasound guided Thoracic Interfascial plane Block (TIFB), Ultrasound guided Erector Spinae plane Block (ESPB)
- Volunteers
- 90 people
- Sponsor
- Tanta University
Chronic Pain Syndrome
The Analgesic Efficacy Supra-scapular Nerve RF After Breast Surgery
Eighty patients with chronic shoulder pain after breast surgery were allocated randomly into 2 groups; forty patients received fluoroscopically guided supra-scapular nerve pulsed radiofrequency (PRF) followed by injection of…
- Trial name
- NCT03247842
- Testing
- suprascapular nerve block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University