Clinical trials: Post-Mastectomy
Breast Carcinoma
Testing the Application of Mepitel Film During Radiation Therapy to Reduce Radiation Related Redness and Peeling in Breast Cancer Patients Following Mastectomy
This phase III trial studies how well Mepitel Film works in reducing radiation dermatitis (redness and peeling) in patients with breast cancer during radiation therapy after a mastectomy.
- Trial name
- NCT04989504
- Testing
- Best Practice, Wound Dressing Material, Quality-of-Life Assessment
- Where
- 49 sites in United States
- Volunteers
- 216 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Modified Radical Mastectomy, Breast Cancer
Comparison Between Erector Spinae Plane Block Versus Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy
The goal of this clinical trial is to compare Ultrasound Guided Erector Spinae and Ultrasound Guided Serratus Anterior Plane Block post Modified Radical Mastectomy in adult females.
- Trial name
- FMASUMD66/2025 (NCT06947330)
- Testing
- Unilateral Erector Spinae group, Unilateral Serratus Anterior group
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kholoud Usama
Nonmalignant Breast Conditions, Breast Cancer
Trial of Drain Antisepsis After Tissue Expander Breast Reconstruction
Surgical site infection (SSI) after breast and axillary surgery occurs more often than for other clean surgical procedures. Infection in the setting of a tissue expander can be devastating and can lead to early implant loss and…
- Trial name
- NCT01286168
- Testing
- Sodium hypochlorite (Dakin's Solution), Chlorhexidine gluconate disk, Control
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Chronic Pain
Prediction of Persistent Post-Mastectomy Pain
Chronic pain is devastating both to individuals and society. In an aging population, surgery is an increasing cause of chronic pain, with rates of persistent post-operative pain ranging from 10-65%.In particular, Persistent…
- Trial name
- NCT02329574
- Where
- United States
- Volunteers
- 259 people
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
Localization of Intercostal Perforating Vessels Reduces Wound Complications From Nipple Sparing Mastectomy
Approximately 100 women scheduled for NSM will be consented pre-operatively to participate in the study. US will be performed after induction of general anesthesia, prior to surgery using Sonosite™ portable US, 5-12mHz transducer…
- Trial name
- NCT02938390
- Testing
- Ultrasound for localizing intercostal perforating vessels
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Amita Health
Mastectomy, Breast Cancer
Post-Mastectomy Analgesia Using Exparel (Liposomal) Versus Standard Bupivacaine or Placebo
This is a randomized, single-blinded placebo-controlled trial. Patients will be randomized to one of three arms: (1) injection of liposomal bupivacaine at the end of the operation, (2) injection of standard bupivacaine at the end…
- Trial name
- NCT03504865
- Testing
- Liposomal bupivacaine, Standard bupivacaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Georgetown University
Analgesia
Open Versus Ultrasound Approach for Serratus Anterior Block
Ultrasound-guided Serratus anterior plane (SAP) block is an interventional technique that recently gained popularity in the context of postoperative analgesia after breast surgery.
- Trial name
- NCT04841564
- Testing
- ultrasound approach of serratus anterior block, open approach of serratus anterior block
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Mansoura University
Shoulder Dysfunction, Breast Cancer
Effects of Exercise Training at Different Timeline on Shoulder Dysfunction After Breast Cancer Modified Radical Mastectomy
Patients who underwent modified radical mastectomy were enrolled in the study. 200 subjects were randomly divided into 4 groups: 7 days postoperative shoulder isotonic training + 4 weeks postoperative progressive resistance…
- Conditions
- Shoulder Dysfunction, Breast Cancer, Modified Radical Mastectomy
- Trial name
- NCT03658265
- Testing
- 7 days SIE plus 4 weeks PRE, 7 days SIE plus 3 weeks PRE, 3 days SIE plus 4 weeks PRE
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Wuhan University
Post Mastectomy Lymphedema
Effect of Resisted Deep Breathing and Myofascial Release in Postmastectomy
This study aims to determine the combined effect of resisted deep breathing and Myofascial release on pain, respiratory efficiency, chest mobility and lymph edema in Postmastectomy.
- Trial name
- NCT07576270
- Testing
- Resisted Deep Breathing, Myofascial release
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Postoperative Pain
Analgesic Strategies After Mastectomy: RIB vs RIB + DPIPB
This retrospective observational study evaluates postoperative pain outcomes in patients undergoing elective mastectomy who received systemic analgesia, rhomboid intercostal block (RIB), or combined rhomboid intercostal block…
- Trial name
- NCT07401602
- Testing
- Analgesic Strategy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istinye University
Horner's Syndrome
Horner's SD After Thoracic Epidural Block
This study prospectively evaluates the incidence of Horner's syndrome after thoracic epidural anesthesia following continuous thoracic epidural analgesia for mastectomy.
- Trial name
- NCT02130739
- Testing
- thoracic epidural anesthesia, mastectomy, Ropivacaine
- Where
- South Korea
- Volunteers
- 450 people
- Sponsor
- Soonchunhyang University Hospital
Post-Mastectomy Chronic Pain Syndrome (Disorder)
Treatment of Postmastectomy Pain Syndrome With Fat Grafting
This study evaluates the possible beneficial effect of fat grafting for post mastectomy pain syndrome. Half of patients will receive fat grafting and the other half of patients will receive sham.
- Trial name
- NCT03081286
- Testing
- Liposuction, Fat graft
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Breast Cancer Female
Efficacy of Transdermal Fentanyl Patches in Relief of Acute Postoperative Pain After Mastectomy
to determine the safety, efficacy and tolerability of transdermal fentanyl in patients undergoing mastectomy, as well as the postoperative consumption of analgesic.
- Trial name
- NCT03051503
- Testing
- The Transdermal Therapeutic System-Fentanyl (TTS-F), Intravenous patient-controlled analgesia (PCA) morphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Post-mastectomy Pain Syndrome
Effects of Intraoperative Esmolol on Post-mastectomy Pain Syndrome
Chronic postoperative pain is an entity that is usually neglected by anesthetists, but several studies show that the choice of anesthetic technique may interfere with this prevalence.
- Trial name
- NCT03965442
- Testing
- Control, Esmolol
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Hospital de Base
Breast Carcinoma
Myofascial Release or Trigger Point Injections for the Reduction of Post-Mastectomy Pain Syndrome
This clinical trial studies the effect of myofascial release in decreasing post-mastectomy pain compared to standard of care trigger point injections in patients with post-mastectomy pain syndrome.
- Trial name
- NCT05041751
- Testing
- Acupuncture Point Injection, Massage Therapy, Quality-of-Life Assessment
- Sponsor
- M.D. Anderson Cancer Center
Postoperative Pain
Efficacy of Dexmedetomidine on Postoperative Analgesia
This prospective, randomized, double-blind study is designed to evaluate the postoperative analgesic efficacy of dexmedetomidine as an adjunct to ropivacaine in erector spinae block in patients undergoing radical mastectomy.
- Trial name
- EDPARMRCT (NCT05110339)
- Testing
- Ropivacaine plus dexmedetomidine, Ropivacaine
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- Universidad Autónoma de Tamaulipas
Scar Improvement, Cosmetic Outcome
Tape Application Protocol for Enhanced Scars
What is the purpose of this study? The Investigators want to find out whether applying Micropore surgical tape to the medial half of the mastectomy scar for 3 months helps improve its appearance after 12 months, compared to no…
- Trial name
- TAPES (NCT07144046)
- Testing
- Micropore covering of the medial half of the scar
- Volunteers
- 90 people
- Sponsor
- Herlev Hospital
Neuropathic Pain Induced by Mastectomy
Lidocaine IV Injection With Different Doses for Patients With Neuropathic Pain After Mastectomy
cancer has become the most common malignancy affecting women worldwide, and its incidence is increasing annually. According to the Global Cancer Observatory (GLOBOCAN) 2020 published by the International Agency for Research on…
- Trial name
- NCT07475520
- Testing
- Lidocaine 2%, Lidocaine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Sentinel Lymph Node Biopsy, Mastectomy, Subcutaneous
SLNB After Nipple Sparing Mastectomy
Sentinel Lymph Node Biopsy (SLNB) after nipple sparing mastectomy (NSM) is controversial. This study aims to investigate feasibility of SLNB with radioisotope method.
- Trial name
- NCT04140188
- Testing
- Senti-Scint (99mTc- pertechnetate combined with human albumin)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Ductal Breast Carcinoma, Invasive Breast Carcinoma
Hypofractionated Radiation Therapy After Mastectomy in Preventing Recurrence in Patients With Stage IIa-IIIa Breast Cancer
This randomized phase III trial studies how well hypofractionated radiation therapy works in preventing recurrence in patients with stage IIa-IIIa cancer who have undergone mastectomy.
- Conditions
- Ductal Breast Carcinoma, Invasive Breast Carcinoma, Lobular Breast Carcinoma, Medullary Breast Carcinoma
- Trial name
- NCT03414970
- Testing
- Radiation Therapy, Questionnaire Administration, Quality-of-Life Assessment
- Where
- 859 sites in United States, Canada
- Volunteers
- 898 people
- Sponsor
- Alliance for Clinical Trials in Oncology