Clinical trials: Post-Op Complication
Pain, Post Operative, Quality of Life
Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft
The goal of this randomized clinical trial is to compare patient-reported pain and oral health-related quality of life during the first postoperative week following extraction and bone graft surgery in patients who received…
- Trial name
- NCT05919745
- Testing
- Ibuprofen 600 mg, Acetaminophen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marquette University
Surgical Site Infection
Surgical Site Infection in Caesarean Section Using Alexis O Compared to Metal Retractors
Objective: To investigate if the use of the newly designed Alexis O Retractor leads to improved intra-operative and post-operative surgical outcomes in the setting of planned elective Caesarean Sections.
- Trial name
- NCT02685696
- Testing
- Alexis O Retractor, Metal Retractor
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Breast Cancer
Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies
Perform a comparison of effective pain relief duration between liposomal bupivacaine and dexmedetomidine when added to bupivacaine in a block for mastectomy for cancer surgery.
- Trial name
- NCT06252662
- Testing
- Dexmedetomidine, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Prosthesis Survival
Prosthetic Management of All on Four Versus All on Six to Rehabilitate Completely Edentulous Maxillary Ridge Opposed by Natural Teeth
the aim of the study to compare the anterior maxillary bone index changes for patient rehabilitated with implant supported fixed prosthesis opposed by natural teeth
- Trial name
- NCT06114069
- Testing
- implant supported maxillary fixed prosthesis
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Anesthesia, Nasal Surgery
The Effect of Pharyngeal Packing on Postoperative Gastric Volume in Patients Undergoing Nasal Surgery
Pharyngeal packing is a frequently used application to reduce the incidence and severity of postoperative nausea and vomiting (PONV) in patients who undergo nasal surgery.
- Conditions
- Anesthesia, Nasal Surgery, Pharyngeal Packing, Gastric Volume
- Trial name
- NCT04819659
- Testing
- Pharyngeal packing
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Pain, Acute, Nausea
Enhanced Recovery Strategies in Elective Breast Surgery
Postoperative pain, nausea, and vomiting are frustrating sequelae of elective breast surgery. Poorly managed postoperative pain can lead to increased opioid use, increased postoperative nausea and vomiting (PONV), delayed return…
- Conditions
- Pain, Acute, Nausea, Vomiting, Postoperative, Opioid Use
- Trial name
- NCT03187080
- Testing
- Paravertebral block procedure using either local anesthetic (0.25% bupivacaine) or sterile saline, Enhanced recovery after breast surgery (ERABS) strategies, Paravertebral block using local anesthetic
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Postoperative Pain, Opioid Use
SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A
The suprazygomatic maxillary nerve (SZMN) block is a well-established, safe and effective regional technique for pain management following cleft palate procedures, however, have not been studied for patients undergoing…
- Trial name
- SZMN (NCT04797559)
- Testing
- SZMN Block
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pulp Necrosis, Postoperative Pain
Evaluation of Post-operative Pain and Bacterial Load Reduction After Application of Three Intra-canal Medications (Cocoa Husk Versus Calcium Hydroxide With and Without Cocoa) in Necrotic Mandibular First Molar.
The study will aim to evaluate the postoperative pain and bacterial load after application of two intracanal medications in mandibular first molar teeth with necrotic pulp.
- Trial name
- NCT07790796
- Testing
- Root canal treatment with intracanal medication by calcium hydroxide for one week., Root canal treatment with intracanal medication by cocoa husk for one week, Root canal treatment with intracanal medication by calcium hydroxide with cocoa husk for one week.
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Post-operative Pain, Post-operative Anxiety
Aromatherapy Effect on Pain and Anxiety After C-section
A prospective randomized triple blinded study conducted in the obstetrics gynecology department of Ben Arous hospital over a period of four months and 10 days between April 2023 and August 2023.
- Trial name
- NCT06387849
- Testing
- Aromatherapy
- Where
- Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Quality of Recovery, Anesthesia
Improving ObsQoR-11 With Continuous Wound Infusion Versus Intrathecal Morphine After Elective Cesarean Delivery
The purpose of this prospective randomized double-blinded and controlled study is to evaluate the quality of recovery after elective cesarean delivery using the Obstetric Quality-of-Recovery-11 (ObsQoR-11) score at 24 hours…
- Conditions
- Quality of Recovery, Anesthesia, Postoperative Pain, Cesarean Section
- Trial name
- CIVIMEC (NCT05696678)
- Testing
- Intrathecal Morphine, Ropivacaine 0.2%
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Postoperative Pain
Comparative Study of the Analgesic Effect of Spinal Anesthesia or Infiltration Anesthesia for Hemorrhoidectomy
Background and Objectives: Postoperative analgesia and early recovery are relevant for hospital discharge after hemorrhoidectomy.
- Trial name
- NCT02839538
- Testing
- Local Infiltration, Subarachnoidal block
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Hysteroscopic Surgery, Pain, Postoperative
A Trial for Peroperative Procedure and Postoperative Pain After Rectal Misoprostol or Rectal Hyoscine Administration
Dilatation of the cervix is necessary before operative hysteroscopic procedures. This dilatation with Hegar dilators has certain difficulties and is associated with pain.
- Trial name
- NCT03359655
- Testing
- Misoprostol, Hyoscine butyl bromide
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Anesthesia, Local, Postoperative Pain
Comparison of Supraclavicular and Costoclavicular Brachial Plexus Blocks in Pediatrics
In upper extremity surgeries, the brachial plexus block can be performed with different techniques at various levels depending on the proximal and distal level of the surgery.
- Trial name
- NCT04782778
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Pain, Postoperative, Pain, Chronic
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).
- Conditions
- Pain, Postoperative, Pain, Chronic, Pain, Acute, Surgical Injury
- Trial name
- NCT04439552
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Postoperative Nausea and Vomiting
Risk Factors for Postoperative Nausea, Vomiting and Pruritus
In this study we would like to identify demographic and individual risk factors that place parturients at a higher risk for postoperative nausea and vomiting (PONV) and itching following administered neuraxial morphine for…
- Trial name
- NCT03178058
- Testing
- Questionaire
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Postoperative Pain, Postoperative Complications
Comparison of the Efficacy of Peripheral Nerve Blocks in Major Open Gynaecological Cancer Surgery
The aim of this prospective randomized study was to compare the effectiveness of subcostal transversus abdominis plane block or rectus sheath block applied in addition to posterior transversus abdominis plane block for…
- Conditions
- Postoperative Pain, Postoperative Complications, Analgesia, Regional Anesthesia Morbidity
- Trial name
- NCT06342076
- Testing
- Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block, Patients undergoing rectus sheat block and posterior transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Pain, Postoperative, Palate; Wound
Use of Tilapia Skin for Palate Repair and Protection After Graft Removal
Randomised Clinical Study to evaluate the efficacy of tilapia skin as an occlusive biological dressing on palatal wound healing after free gingival graft harvesting.
- Conditions
- Pain, Postoperative, Palate; Wound, Cicatrization
- Trial name
- NCT04168125
- Testing
- Tilapia skin, Surgical Wound Dressing
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Nursing Caries, Pain, Postoperative
Effect of Foot Bath on Postoperative Sleep Quality and Pain
One of the most common problems in patients in the postoperative period is pain and the associated deterioration in sleep quality. Deterioration in sleep quality can cause pain to be perceived more severely.
- Conditions
- Nursing Caries, Pain, Postoperative, Sleep Deprivation
- Trial name
- NCT05705908
- Testing
- Hot Foot Bath 1, Hot Foot Bath 2
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Cardiac Surgery, Postoperative Cognitive Dysfunction
The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart Surgery
To assess the impact of Dexmedetomidine on postoperative cognitive function and serum Neuron Specific Enolase levels as an indicator of neuronal injury in patients undergoing open heart surgery
- Conditions
- Cardiac Surgery, Postoperative Cognitive Dysfunction, Neurologic Manifestations
- Trial name
- NCT06655025
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sohag University
Analgesia, Post-Operative Pain
A Prospective Pilot Study of a Non-Narcotic Post-Operative Course After Colectomy
With this pilot investigation, the investigators aim to challenge the reliance on opiate analgesia following colon and rectal surgery.
- Conditions
- Analgesia, Post-Operative Pain, Breakthrough Pain, Colectomy
- Trial name
- NCT05200806
- Testing
- Non-Narcotic ERAS Post-Operative Pain Management
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Vermont
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