Clinical trials: Post-Operative Atrial Fibrillation
Atrial Fibrillation, Arrhythmias, Cardiac
Low Workload Concept for the Detection of Silent Atrial Fibrillation (AF) and Atrial Fibrillation Burden in Patients At High Risk of AF and Stroke
Patient-centered novel e-health technology and services will lay the foundation for future healthcare systems and services to support health and welfare promotion.
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases
- Trial name
- CARE-DETECT (NCT05351775)
- Testing
- Smartphone application, Bed sensor, Wrist-worn photoplethysmography (PPG) and accelerometer data logger.
- Where
- Finland
- Volunteers
- 150 people
- Sponsor
- University of Turku
Post Operative Atrial Fibrillation
The Impact of Oral Vitamin C in Prevention for Post Operative Atrial Fibrillation (POAF) in Coronary Artery Bypass Surgery (CABG) Patients
Post operative atrial fibrillation (POAF) is one of the most common complications that takes place worldwide after coronary artery bypass surgeries (CABG).
- Trial name
- NCT06074367
- Testing
- Vitamin C 500 MG Oral Capsule(High dose 2g daily), Vitamin C 500 MG Oral Capsule(Low-dose 1g daily)
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Helwan University
Atrial Fibrillation, Acute Kidney Injury
Autonomic State, Cardiovascular Control and Outcomes in Coronary Surgery
Characterization of the perioperative autonomic nervous system state, cardiovascular and cerebrovascular control and microcirculation in order to predict postoperative atrial fibrillation and acute kidney injury in patients…
- Trial name
- NCT03169608
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Policlinico S. Donato
Atrial Fibrillation, Atrial Flutter
Pericardiotomy in Cardiac Surgery
PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Cardiac Events
- Trial name
- PRINCE (NCT06486636)
- Testing
- Left Posterior Pericardiotomy
- Where
- 19 sites in United States, Austria and 3 more
- Volunteers
- 1,400 people
- Sponsor
- Population Health Research Institute
Atrial Fibrillation, Myocardium; Injury
Statin Therapy In Cardiac Surgery
The purpose of STICS trial (Statin Therapy In Cardiac Surgery) is to test whether perioperative treatment with Rosuvastatin 20 mg once daily prevents post-operative atrial fibrillation and reduces perioperative irreversible…
- Trial name
- STICS (NCT01573143)
- Testing
- Rosuvastatin
- Where
- China
- Volunteers
- 1,922 people
- Sponsor
- University of Oxford
Atrial Fibrillation
The Effect of Posterior Pericardiotomy on the Incidence of Atrial Fibrillation After Cardiac Surgery
The purpose of this study is to determine if preforming a posterior left pericardiotomy prevents atrial fibrillation after cardiac surgery.
- Trial name
- PALACS (NCT02875405)
- Testing
- Posterior left pericardiotomy
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Weill Medical College of Cornell University
Postoperative Atrial Fibrillation, Lung Surgery
Perioperative Statins to Prevent AFib After Lung Surgery
The goal of this clinical trial is to learn whether short-term treatment with atorvastatin can prevent new abnormal rapid heart rhythms after lung surgery in adults aged 60 years or older who are scheduled to have a lung segment…
- Trial name
- STAT-LUNG (NCT07727681)
- Testing
- Atorvastatin
- Where
- 2 sites in China
- Volunteers
- 540 people
- Sponsor
- Peking Union Medical College Hospital
Coronary Arterial Disease (CAD), Valve Replacement
Prolonged Chest Tube Treatment to Reduce Rates of Atrial Fibrillation Following Cardiac Surgery
Evacuation of pericardial blood by posterior pericardiotomy or use of a posterior pericardial chest tube lowers postoperative atrial fibrillation (POAF) rates after cardiac surgery by 45-68%.
- Conditions
- Coronary Arterial Disease (CAD), Valve Replacement, Aortic Surgery
- Trial name
- PROPER (NCT06800781)
- Testing
- Prolonged treatment with posterior pericardial chest tube plus standard care
- Where
- Sweden
- Volunteers
- 624 people
- Sponsor
- Region Skane
Post-operative Atrial Fibrillation, Cardiovascular Diseases
Association Between GalectiN-3 and pOSt-operative atrIal Fibrillation After Coronary Artery bypaSs Graft
The goal of this observational study is to test the association between high levels of Galectin-3 and the occurrence of post-operative atrial fibrillation after isolated coronary artery bypass grafting (CABG).
- Conditions
- Post-operative Atrial Fibrillation, Cardiovascular Diseases, Post-pericardiotomy Syndrome
- Trial name
- GNOSIS (NCT06768528)
- Testing
- Galectin-3 dosage
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Atrial Fibrillation New Onset
Stellate Ganglion to Prevent Atrial Fibrillation
New onset atrial fibrillation is a common problem after cardiac surgery. The reported incidence after coronary artery bypass grafting (CABG) is 15-40%, 37-50% after valve surgery, and up to 60% after CABG and valve surgery.
- Trial name
- NCT05656170
- Testing
- Stellate ganglion block, Bupivacain, Saline
- Sponsor
- Rush University Medical Center
AKI, Neurocognitive Disorders
El DORADO STUDY (Evaluation of Delivery of Oxygen on Renal, Arrhythmia and Delirium Outcomes Study)
The study aims to develop a novel perioperative noninvasive delivery of oxygen (DO2) and hemodynamic index in the prediction of postoperative outcomes including post-operative acute kidney injury (POAKI), perioperative…
- Conditions
- AKI, Neurocognitive Disorders, Atrial Fibrillation
- Trial name
- NCT04895384
- Testing
- Edwards ClearSight and Masimo SET
- Where
- 2 sites in Singapore
- Volunteers
- 600 people
- Sponsor
- National University Hospital, Singapore
Post Operative Atrial Fibrillation
Post Operative Atrial Fibrillation Post Cardiac Surgery ( CABG and VALVE REPLACEMENT )
This study aims to assess the percent and risk factors of postoperative atrial fibrillation in patients undergoing cardiac surgery in Assiut university heart hospital
- Trial name
- NCT06763120
- Where
- Egypt
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Assiut University
Coronary Artery Disease, Stroke
Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass
Surgical occlusion of the left atrial appendage (LAAO) is sometimes performed during the cardiac surgery to reduce long-term risk of stroke.A previous study found that LAAO may be associated with increased risk of postoperative…
- Conditions
- Coronary Artery Disease, Stroke, Atrial Fibrillation
- Trial name
- NCT04220047
- Testing
- Left Atrial Appendage Resection and Marshall Ligament Amputation
- Where
- China
- Volunteers
- 400 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Bypass Grafting, Postoperative Atrial Fibrillation
Once Versus Twice Bisoprolol Dosage Regimen in Prevention of Atrial Fibrillation Post Coronary Artery Bypass Graft Surgery
The goal of this interventional clinical trial is compare between two different dose regimens of bisoprolol (beta-blocker) in CABG patients in terms of efficacy and safety.
- Conditions
- Coronary Artery Bypass Grafting, Postoperative Atrial Fibrillation, Coronary Artery Disease
- Trial name
- NCT05730413
- Testing
- Bisoprolol
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Cairo University
Atrial Fibrillation (AF), Hypomagnesemia
Postoperative Incidence of Atrial Fibrillation Following Cardiac Surgery
Introduction: Postoperative atrial fibrillation is one of the most frequent complications in cardiac surgery, with an expected incidence of more than 50% following valve surgery.
- Conditions
- Atrial Fibrillation (AF), Hypomagnesemia, Cardiac Surgery
- Trial name
- NCT06855550
- Where
- Colombia
- Volunteers
- 435 people
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Postoperative Atrial Fibrillation
Prevention of Postoperative Atrial Fibrillation
The primary aim of this study is to determine the safest and most effective therapeutic strategy to decrease the incidence of postoperative atrial fibrillation following cardiac surgery in an era with shorter ICU and hospital…
- Trial name
- NCT01742039
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- George Washington University
Atrial Fibrillation
Treatment of Postoperative Atrial Fibrillation - Comparison of Amiodarone and Placebo.
Post-operative atrial fibrillation (POAF) is the most common complication encountered after cardiac surgery; reports show POAF to occur in ~ 35% of patients after CABG.
- Trial name
- NCT02715687
- Testing
- Amiodarone
- Volunteers
- 400 people
- Sponsor
- Rambam Health Care Campus
Cardiac Surgery, Peri Operative Medicine
Risk Factors of Atrial Fibrillation After Cardiac Surgery
Supraventricular arrhythmias complicate more than 40% of cardiac surgeries and are associated with an increased risk of bleeding, stroke, heart failure, and death.
- Conditions
- Cardiac Surgery, Peri Operative Medicine, Thoracic Surgery, Cardiopulmonary Bypass
- Trial name
- PFAS (NCT07625033)
- Where
- France
- Volunteers
- 918 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Post Cardiac Surgery Atrial Fibrillation
The Outcomes of Sympathetic Cardiac Denervation on Postoperative Atrial Fibrillation After Cardiac Surgery, Randomized Controlled Trial
we compare the effect of cutting heart nerves in one group of patients with open heart surgery and other group without cutting oh development of disturbance of heart beat after surgery
- Trial name
- NCT07811817
- Testing
- cardiac sympathetic denervation, Standard open-heart surgery without additional epicardial or fat pad dissection.
- Where
- Egypt
- Volunteers
- 560 people
- Sponsor
- Zagazig University
Postoperative Atrial Fibrillation
Post-Operative Atrial Fibrillation After Surgical Aortic Valve Replacement and the Influence of Statins
Statins have rapid and significant actions that have potentially important (but not yet proven) implications for postoperative atrial fibrillation and cardiac protection in patients undergoing cardiac surgery.
- Trial name
- NCT05062239
- Testing
- Discontinuance of treatment with statins 7 to 14 days prior to surgery until 30 days postoperative, No-intervention.
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Lars Peter Riber