Clinical trials: Post-Operative Condition
Post-operative Pain, Acute
Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Post-operative Pain Relief and Decrease Opioid Consumption: a Prospective Randomized Controlled Trial
The purpose of this study is to determine whether the addition of magnesium to bupivacaine for the post-operative adductor canal blocks (ACB) can decrease opioid consumption and improve pain management for patients after same-day…
- Trial name
- NCT05004636
- Testing
- Adding Magnesium as an adjuvant to the adductor canal Block (ACB) for same-day discharge total knee arthroplasty
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Wayne State University
Surgical Site Infection
Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™
The purpose of this pilot study is to evaluate antimicrobial properties of a single test product, a vehicle product and a reference product applied in two different areas when used as a patient preoperative skin preparation.
- Trial name
- ZX-ZP-0035 (NCT02221232)
- Testing
- Chloraprep, ZuraPrep, ZuraPrep Vehicle
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Atrial Fibrillation
Safety and Efficacy Study of Amniotic Membrane Patch to Treat Postoperative Atrial Fibrillation
The purpose of this study is to to evaluate the rate of new onset postoperative atrial fibrillation in subjects receiving the amniotic membrane patch placed on the epicardial surface as compared to subjects who did not undergo…
- Trial name
- NCT02193321
- Testing
- Amniotic Membrane Patch
- Where
- United States
- Sponsor
- University of Arizona
Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction
Effect of Coughing Exercises Versus Incentive Spirometry on Respiratory Function and Recovery in Children After Cardiac Surgery.
This study examines the effects of coughing exercises and incentive spirometry (IS) on lung function and recovery in children who undergo heart surgery.
- Conditions
- Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction, Postoperative Recovery After Cardiac Surgery
- Trial name
- CEXIS (NCT07405333)
- Testing
- Coughing Exercises, Incentive Spirometry, Standard Postoperative Care
- Where
- 4 sites in Iraq
- Volunteers
- 99 people
- Sponsor
- University of Baghdad
Pain, Postoperative
Effective Postoperative Pain Relief After Laparoscopic Cholecystectomy With TENS
The study evaluates the effect of TENS (transcutaneous electrical nerve stimulation) treatment for first line of treatment compared with conventional treatment with opioids on pain relief and time spent time in the…
- Trial name
- NCT04114149
- Testing
- TENS (transcutaneous electrical nerve stimulation), iv opioid
- Where
- Sweden
- Volunteers
- 166 people
- Sponsor
- Göteborg University
Postoperative Nausea and Vomiting
Paracetamol on Postoperative Nausea and Vomiting
The drugs with both high potency and low side effects are preferred in the prevention of postoperative nausea and vomiting (PONV) which is a common problem.
- Trial name
- NCT03588338
- Testing
- Perfalgan, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Shoulder Pain
Post Laparoscopy Shoulder Pain and Postoperative Trendelenburg Position
Laparoscopic surgery has become a standard of care for many gynecological surgeries due to its lower morbidity, pain and cost compared to open techniques.
- Trial name
- NCT04129385
- Testing
- 20 degree Trendelenburg position
- Where
- Lebanon
- Volunteers
- 108 people
- Sponsor
- American University of Beirut Medical Center
Postoperative Delirium
The Effect of Bupivacaine Liposome Preemptive Analgesia on Postoperative Pain and Delirium in Elderly Patients Undergoing Hip Fracture Surgery
To explore the effects of bupivacaine liposomes in preemptive analgesia for iliofascial block on postoperative pain and postoperative delirium in elderly patients with hip fractures, to optimize perioperative analgesia…
- Trial name
- NCT07066111
- Testing
- Tramadol, bupivacaine liposome (ultrasound-guided high iliofascial space block)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Dexmedetomidine, Lidocaine
Intravenous Lidocaine Plus Intratracheal Dexmedetomidine on Postoperative Sore Throat
Objective: The present study was to investigate the effect of intravenous lidocaine combined with intratracheal dexmedetomidine on postoperative sore throat in patients undergoing thyroid cancer surgery.
- Conditions
- Dexmedetomidine, Lidocaine, Sore Throat
- Trial name
- NCT06952309
- Testing
- Intracheal dexmedetomidine, Intravenous lidocaine, Intravenous lidocaine combined with intracheal dexmedetomidine
- Volunteers
- 144 people
- Sponsor
- Anqing Municipal Hospital
Hip Osteoarthritis, Hip Injuries
Positioning for Hip Arthroscopic Surgery to Reduce Postoperative Numbness
Compared to the knee and shoulder, the hip joint leaves relatively little space to maneuver arthroscopic instruments and camera.
- Conditions
- Hip Osteoarthritis, Hip Injuries, Hip Sprain, Hip Strain
- Trial name
- NCT05038709
- Testing
- The Pink Pad Hip Kit
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Head and Neck Cancer
A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Locally Advanced Head and Neck Cancer Receiving Postoperative Radiotherapy
The purpose of this study is to evaluate the efficacy, safety and tolerability of palifermin on the incidence of oral mucositis in subjects with locally advanced head and neck cancer receiving postoperative radiotherapy.
- Trial name
- NCT00540332
- Testing
- palifermin
- Sponsor
- Swedish Orphan Biovitrum
Postoperative Pain, Knee Arthroplasty
The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Revision Knee Arthroplasty
The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing pain and morphine consumption after revision knee arthroplasty.
- Trial name
- NCT01191593
- Testing
- Adductor-Canal-Blockade with Ropivacaine, Adductor-Canal-blockade with saline
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postoperative Pain
Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management
The ability to predict pain and then apply modified treatment protocols has been limited. Current practice is for physicians to select standard post-operative pain treatment protocols without patient consultation.
- Trial name
- NCT02605187
- Testing
- No choice given, Choice given, Ibuprofen
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Stanford University
Postoperative Complications
Intraoperative Fluid Management Guided by Internal Jugular Vein on Postoperative Complications in Abdominal Surgeries
This study investigates the role of respiratory variation in the internal jugular vein as a tool for intraoperative fluid management during abdominal surgeries under general anesthesia.
- Trial name
- NCT07041021
- Testing
- Respiratory variation of the Internal Jugular Vein (IJV)
- Where
- 2 sites in Egypt
- Volunteers
- 84 people
- Sponsor
- Suez Canal University
Opioid-Free Anesthesia, Laparoscopic Sleeve Gastrectomy
Effect of Opioid-free Analgesia and Anesthesia on the Quality of Postoperative Recovery and Nausea Vomit in Patients Receiving Laparoscopic Sleeve Gastrectomy
The purpose of the intraoperative use of opioids is to reduce the amount of sedative medication and to ensure effective analgesia.
- Conditions
- Opioid-Free Anesthesia, Laparoscopic Sleeve Gastrectomy, Postoperative Vomiting, Postoperative Recovery
- Trial name
- NCT06305221
- Testing
- Opioid-free Analgesics (esketamine, dexmedetomidine), Opioid Anesthetics (sufentanil and remifentanil)
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Beijing Friendship Hospital
Inflammation, Cataract
Study of Dexycu in Treating Intraocular Inflammation
This is a phase III, prospective, randomised, double-masked, placebo-controlled, parallel-design, multicenter study of the efficacy, safety and pharmacokinetics of 9% dexamethasone intraocular injection for the treatment of…
- Trial name
- NCT06429306
- Testing
- Dexycu
- Where
- China
- Volunteers
- 285 people
- Sponsor
- Ocumension Therapeutics (Shanghai) Co., Ltd
Chronic Low-back Pain, Herniated Disc
LISA Post Market Clinical Follow-Up Study: Documentation of Clinical Outcomes After Surgery With LISA Implant
The study is a post-market surveillance study of the Lumbar Implant for Stiffness Augmentation (LISA), a medical device, which is used to treat low-back pain that accompanies degenerative lesions of grades II, III, and IV…
- Conditions
- Chronic Low-back Pain, Herniated Disc, Degenerative Disc Disease, Lumbar Canal Stenosis
- Trial name
- LISA-PMCF (NCT04631133)
- Testing
- Lumbar Implant for Stiffness Augmentation (LISA)
- Where
- 5 sites in Denmark, France and 1 more
- Volunteers
- 136 people
- Sponsor
- BACKBONE
Hernias, Diaphragmatic, Congenital
Resistance Exercise in Children With Post-operative Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a life-threatening condition with long-term complications including respiratory tract infections, respiratory muscle weakness, and abnormal lung functions.
- Trial name
- hernia (NCT04900649)
- Testing
- chest resistance exercise, chest expansion exercises
- Where
- Saudi Arabia
- Volunteers
- 32 people
- Sponsor
- Qassim University
Cardiac Infarct, Cardiac Valve Disease
Frailty, Physical Capacity and Lung Function in Postoperative Cardiac Surgery Patients
The goal of this observational and prospective study is to investigate changes in physical performance, lung function, and respiratory and peripheral muscle strength in patients during the postoperative period following coronary…
- Conditions
- Cardiac Infarct, Cardiac Valve Disease, Fragility, Physical Disability
- Trial name
- NCT06247358
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo General Hospital
Intravenous Drug Usage, Ibuprofen
Postoperative Analgesic Effects of Ibuprofen Versus Ketorolac in Patients Undergoing in Orthopedic Surgery
Objectives: To compare the postoperative analgesic effects of ibuprofen versus ketorolac in patients undergoing orthopedic surgery at Combined Military Hospital, Rawalpindi.
- Conditions
- Intravenous Drug Usage, Ibuprofen, Ketorolac, Knee Arthroscopy
- Trial name
- NCT05695664
- Testing
- Ibuprofen 800 mg, Ketorolac Injection
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Benazir Bhutto Hospital, Rawalpindi
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